IMP

Process View

Homo sapiens

15 genes annotated in human

Multi-species View

regulation of lymphocyte apoptotic process

GO:0070228

Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of lymphocyte apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of lymphocyte apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.981	Mouse
BIRC3	baculoviral IAP repeat containing 3	0.933	Human
BIRC2	baculoviral IAP repeat containing 2	0.875	Human
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.736
CCR5	chemokine (C-C motif) receptor 5	0.734
BID	BH3 interacting domain death agonist	0.643
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.489
FAS	Fas (TNF receptor superfamily, member 6)	0.475
BMPR1A	bone morphogenetic protein receptor, type IA	0.434
NOXA1	NADPH oxidase activator 1	0.429
XIAP	X-linked inhibitor of apoptosis	0.388	Human
TRAF1	TNF receptor-associated factor 1	0.351
LCK	lymphocyte-specific protein tyrosine kinase	0.341
INSR	insulin receptor	0.283
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.244
CD247	CD247 molecule	0.235
BCL2	B-cell CLL/lymphoma 2	0.234
CFLAR	CASP8 and FADD-like apoptosis regulator	0.218
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.207
RIPK2	receptor-interacting serine-threonine kinase 2	0.179
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.168
CD2	CD2 molecule	0.161
TGIF1	TGFB-induced factor homeobox 1	0.149
IL22RA2	interleukin 22 receptor, alpha 2	0.146
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.145
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.136
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.130
FADD	Fas (TNFRSF6)-associated via death domain	0.126	Mouse
CXCL9	chemokine (C-X-C motif) ligand 9	0.123
MSN	moesin	0.120
SH3RF1	SH3 domain containing ring finger 1	0.117
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.115
CCL4	chemokine (C-C motif) ligand 4	0.114	Human
BCL2L1	BCL2-like 1	0.112
IL10RA	interleukin 10 receptor, alpha	0.109
CCL5	chemokine (C-C motif) ligand 5	0.098
CXCR4	chemokine (C-X-C motif) receptor 4	0.093
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.089	Mouse
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.088
CARD11	caspase recruitment domain family, member 11	0.083
CCR7	chemokine (C-C motif) receptor 7	0.083
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.081
TRAF3	TNF receptor-associated factor 3	0.080
IDE	insulin-degrading enzyme	0.074
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.065
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.061	Human
C9orf89	chromosome 9 open reading frame 89	0.060
PRKCZ	protein kinase C, zeta	0.056	Human
BAK1	BCL2-antagonist/killer 1	0.055
TRAF6	TNF receptor-associated factor 6	0.050
IL22RA1	interleukin 22 receptor, alpha 1	0.047
ICAM1	intercellular adhesion molecule 1	0.042
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.041
CD6	CD6 molecule	0.041
CTSW	cathepsin W	0.041
CD5	CD5 molecule	0.039
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.039
CALCOCO2	calcium binding and coiled-coil domain 2	0.039
TNF	tumor necrosis factor	0.038
PDPK1	3-phosphoinositide dependent protein kinase-1	0.038
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.037
SQSTM1	sequestosome 1	0.036
CD8A	CD8a molecule	0.035
RNR2	l-rRNA	0.034
BIRC5	baculoviral IAP repeat containing 5	0.033
CXCL10	chemokine (C-X-C motif) ligand 10	0.033
TRAF2	TNF receptor-associated factor 2	0.033
APAF1	apoptotic peptidase activating factor 1	0.033
VHL	von Hippel-Lindau tumor suppressor	0.033	Mouse
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.033
FSTL1	follistatin-like 1	0.032
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.032
VCAM1	vascular cell adhesion molecule 1	0.032
CDCP1	CUB domain containing protein 1	0.031
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.031
CXCL11	chemokine (C-X-C motif) ligand 11	0.030
BRCA1	breast cancer 1, early onset	0.030
IL10	interleukin 10	0.029
IL32	interleukin 32	0.029
CA12	carbonic anhydrase XII	0.028
MICA	MHC class I polypeptide-related sequence A	0.027
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.026
TRADD	TNFRSF1A-associated via death domain	0.026
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.025
ANXA2	annexin A2	0.025
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.024
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.024
CCL3	chemokine (C-C motif) ligand 3	0.024	Human
HPCAL4	hippocalcin like 4	0.024
S100A10	S100 calcium binding protein A10	0.024
ZHX1	zinc fingers and homeoboxes 1	0.024
EZR	ezrin	0.023
CCR4	chemokine (C-C motif) receptor 4	0.023
USP15	ubiquitin specific peptidase 15	0.022
ARRB1	arrestin, beta 1	0.022
CYBA	cytochrome b-245, alpha polypeptide	0.022
ANXA5	annexin A5	0.021
ATM	ataxia telangiectasia mutated	0.021
RIPK3	receptor-interacting serine-threonine kinase 3	0.020	Mouse
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.020
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.019
DPP4	dipeptidyl-peptidase 4	0.019
DIABLO	diablo, IAP-binding mitochondrial protein	0.019
TMSB10	thymosin beta 10	0.018
RNF144B	ring finger protein 144B	0.018
CREBBP	CREB binding protein	0.018
GRB10	growth factor receptor-bound protein 10	0.018
CXCL13	chemokine (C-X-C motif) ligand 13	0.018
RGS1	regulator of G-protein signaling 1	0.017
IRS1	insulin receptor substrate 1	0.017
WRN	Werner syndrome, RecQ helicase-like	0.017
IL8	interleukin 8	0.017
PML	promyelocytic leukemia	0.017
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.017
BAD	BCL2-associated agonist of cell death	0.017
GLRX3	glutaredoxin 3	0.017
IL2RG	interleukin 2 receptor, gamma	0.017
EGLN1	egl nine homolog 1 (C. elegans)	0.016
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.016
CCL13	chemokine (C-C motif) ligand 13	0.016	Human
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.015
CRLF3	cytokine receptor-like factor 3	0.015
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.015
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.015
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.015
SYK	spleen tyrosine kinase	0.014
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.014
CCL20	chemokine (C-C motif) ligand 20	0.014	Human
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.014
INCENP	inner centromere protein antigens 135/155kDa	0.014
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.014	Human
CCL2	chemokine (C-C motif) ligand 2	0.014	Human
IL6	interleukin 6 (interferon, beta 2)	0.013
RIPK4	receptor-interacting serine-threonine kinase 4	0.013
IFNG	interferon, gamma	0.013
CD83	CD83 molecule	0.013
SOCS3	suppressor of cytokine signaling 3	0.013
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.013
CDCA8	cell division cycle associated 8	0.013
RB1	retinoblastoma 1	0.013
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.013
CUL2	cullin 2	0.012
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.012	Human
C1QB	complement component 1, q subcomponent, B chain	0.012
ANXA1	annexin A1	0.012
CD40	CD40 molecule, TNF receptor superfamily member 5	0.012
FASLG	Fas ligand (TNF superfamily, member 6)	0.012
CD28	CD28 molecule	0.012
EGLN3	egl nine homolog 3 (C. elegans)	0.012
UBD	ubiquitin D	0.011
CCR1	chemokine (C-C motif) receptor 1	0.011
SGOL1	shugoshin-like 1 (S. pombe)	0.011
GSTO1	glutathione S-transferase omega 1	0.011
IL2RB	interleukin 2 receptor, beta	0.011
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.011
GNLY	granulysin	0.011
CD40LG	CD40 ligand	0.011
BAX	BCL2-associated X protein	0.011	Mouse
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.011
EMP3	epithelial membrane protein 3	0.011
CD52	CD52 molecule	0.011
FZD1	frizzled homolog 1 (Drosophila)	0.011
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.011
IL7R	interleukin 7 receptor	0.011
ZBP1	Z-DNA binding protein 1	0.011
FPR3	formyl peptide receptor 3	0.010
CCL22	chemokine (C-C motif) ligand 22	0.010