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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cytokine mediated signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cytokine mediated signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
ZNF43	zinc finger protein 43	1.000
GHR	growth hormone receptor	0.999
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.995	Human
ZNF253	zinc finger protein 253	0.986
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.984
C1QA	complement component 1, q subcomponent, A chain	0.965	Human
IL1R1	interleukin 1 receptor, type I	0.963
CCR5	chemokine (C-C motif) receptor 5	0.961
JAK2	Janus kinase 2	0.947
ZNF273	zinc finger protein 273	0.946	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.941
SOCS3	suppressor of cytokine signaling 3	0.939
ZNF675	zinc finger protein 675	0.920
CCL4	chemokine (C-C motif) ligand 4	0.895	Human
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.858
NCOR2	nuclear receptor corepressor 2	0.841
TRAF6	TNF receptor-associated factor 6	0.833
CAV2	caveolin 2	0.821
CXCL9	chemokine (C-X-C motif) ligand 9	0.790
ESR1	estrogen receptor 1	0.730
STAT1	signal transducer and activator of transcription 1, 91kDa	0.681
ZNF85	zinc finger protein 85	0.642	Human
C1QC	complement component 1, q subcomponent, C chain	0.626	Human
ZNF708	zinc finger protein 708	0.620	Human
RXRA	retinoid X receptor, alpha	0.574
IL1B	interleukin 1, beta	0.567	Human
ZNF93	zinc finger protein 93	0.562
ZNF117	zinc finger protein 117	0.542	Human
EGFR	epidermal growth factor receptor	0.530
ZNF430	zinc finger protein 430	0.516	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.508
CAV1	caveolin 1, caveolae protein, 22kDa	0.502	Mouse
ZNF680	zinc finger protein 680	0.502	Human
C19orf50	chromosome 19 open reading frame 50	0.453
IL1RN	interleukin 1 receptor antagonist	0.440
APOC1	apolipoprotein C-I	0.436
CCL2	chemokine (C-C motif) ligand 2	0.421	Human
AXL	AXL receptor tyrosine kinase	0.415
STAT4	signal transducer and activator of transcription 4	0.413
A2M	alpha-2-macroglobulin	0.412
ZNF254	zinc finger protein 254	0.412	Human
HNF4A	hepatocyte nuclear factor 4, alpha	0.390
HP	haptoglobin	0.377
PTPRB	protein tyrosine phosphatase, receptor type, B	0.351
IRAK2	interleukin-1 receptor-associated kinase 2	0.303
CCL8	chemokine (C-C motif) ligand 8	0.302	Human
ZNF91	zinc finger protein 91	0.277
CCL5	chemokine (C-C motif) ligand 5	0.272
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.261
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.226
CXCL10	chemokine (C-X-C motif) ligand 10	0.222
ZNF92	zinc finger protein 92	0.212	Human
CCL7	chemokine (C-C motif) ligand 7	0.210	Human
RARA	retinoic acid receptor, alpha	0.202
CCL13	chemokine (C-C motif) ligand 13	0.195	Human
IDE	insulin-degrading enzyme	0.195
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.190	Human
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.190
LAT	linker for activation of T cells	0.174
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.174
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.161
SH2B1	SH2B adaptor protein 1	0.154
IL1R2	interleukin 1 receptor, type II	0.152
FAS	Fas (TNF receptor superfamily, member 6)	0.145
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.144
PRKCDBP	protein kinase C, delta binding protein	0.130
JAK1	Janus kinase 1	0.126
IL2RB	interleukin 2 receptor, beta	0.121
PTEN	phosphatase and tensin homolog	0.118
F2R	coagulation factor II (thrombin) receptor	0.117	Human
CCL19	chemokine (C-C motif) ligand 19	0.116	Human
CCR7	chemokine (C-C motif) receptor 7	0.110
HR	hairless homolog (mouse)	0.109
CCR1	chemokine (C-C motif) receptor 1	0.105
STAT5A	signal transducer and activator of transcription 5A	0.101
ZNF107	zinc finger protein 107	0.101
C1QB	complement component 1, q subcomponent, B chain	0.101	Human
CCL3	chemokine (C-C motif) ligand 3	0.095	Human
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.086
CCL22	chemokine (C-C motif) ligand 22	0.085
CXCL11	chemokine (C-X-C motif) ligand 11	0.083
CPE	carboxypeptidase E	0.078
PPARA	peroxisome proliferator-activated receptor alpha	0.078	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.077
CXCL2	chemokine (C-X-C motif) ligand 2	0.077
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.076
IGF1R	insulin-like growth factor 1 receptor	0.074
IFNG	interferon, gamma	0.072
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.063
ZNF682	zinc finger protein 682	0.062	Human
IL6	interleukin 6 (interferon, beta 2)	0.061
IL7R	interleukin 7 receptor	0.055
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.054
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.053
SOCS2	suppressor of cytokine signaling 2	0.051
TXNRD1	thioredoxin reductase 1	0.049
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.049
ICAM1	intercellular adhesion molecule 1	0.049
SLAMF8	SLAM family member 8	0.049
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.047
CNTF	ciliary neurotrophic factor	0.046
LCAT	lecithin-cholesterol acyltransferase	0.046
PGR	progesterone receptor	0.046
MED25	mediator complex subunit 25	0.044
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.044
ESRRG	estrogen-related receptor gamma	0.043
IRS1	insulin receptor substrate 1	0.042
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.041
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.039
PROCR	protein C receptor, endothelial	0.039
IRAK4	interleukin-1 receptor-associated kinase 4	0.039
OSMR	oncostatin M receptor	0.036	Human
SKIL	SKI-like oncogene	0.036
ENO2	enolase 2 (gamma, neuronal)	0.035
IL6R	interleukin 6 receptor	0.035
MDFI	MyoD family inhibitor	0.034
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.034
NCOA1	nuclear receptor coactivator 1	0.034
CCL11	chemokine (C-C motif) ligand 11	0.034	Human
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.034
CXCL5	chemokine (C-X-C motif) ligand 5	0.033
DARC	Duffy blood group, chemokine receptor	0.033
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.032
IL1RAP	interleukin 1 receptor accessory protein	0.031
IL8	interleukin 8	0.031
SLA	Src-like-adaptor	0.031
OSM	oncostatin M	0.031
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.030
LEPR	leptin receptor	0.030
IFNGR1	interferon gamma receptor 1	0.030
GJA1	gap junction protein, alpha 1, 43kDa	0.030
VCAM1	vascular cell adhesion molecule 1	0.029
ZNF195	zinc finger protein 195	0.029	Human
COMMD1	copper metabolism (Murr1) domain containing 1	0.029
CCR4	chemokine (C-C motif) receptor 4	0.029
EBI3	Epstein-Barr virus induced 3	0.029
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.029
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.028
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.027
SDPR	serum deprivation response	0.027
EPOR	erythropoietin receptor	0.027
FGA	fibrinogen alpha chain	0.026
CAPN1	calpain 1, (mu/I) large subunit	0.026
APOA1	apolipoprotein A-I	0.026
SELE	selectin E	0.025
ANG	angiogenin, ribonuclease, RNase A family, 5	0.025
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.025
STAT5B	signal transducer and activator of transcription 5B	0.024
ZNF320	zinc finger protein 320	0.024
NKG7	natural killer cell group 7 sequence	0.023
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.023
COL6A1	collagen, type VI, alpha 1	0.022
CD83	CD83 molecule	0.022
LOXL4	lysyl oxidase-like 4	0.022
RGS1	regulator of G-protein signaling 1	0.022
IL10RA	interleukin 10 receptor, alpha	0.021
ADAMDEC1	ADAM-like, decysin 1	0.021
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.021
GNLY	granulysin	0.020
CXCR6	chemokine (C-X-C motif) receptor 6	0.020
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.020
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.020	Human
CST7	cystatin F (leukocystatin)	0.020
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.020
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.019
IL1A	interleukin 1, alpha	0.019
CH25H	cholesterol 25-hydroxylase	0.019
FRS2	fibroblast growth factor receptor substrate 2	0.019
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.019
CCR3	chemokine (C-C motif) receptor 3	0.019
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.019
TNF	tumor necrosis factor	0.019
UBD	ubiquitin D	0.019
INSR	insulin receptor	0.018
STAB1	stabilin 1	0.018
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.018	Human
SLAMF7	SLAM family member 7	0.018
FBLN1	fibulin 1	0.018
RIPK2	receptor-interacting serine-threonine kinase 2	0.018
FPR3	formyl peptide receptor 3	0.018
DPP4	dipeptidyl-peptidase 4	0.017
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.017
IL10	interleukin 10	0.017
INHBA	inhibin, beta A	0.017
IL18RAP	interleukin 18 receptor accessory protein	0.017
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.017
SOCS1	suppressor of cytokine signaling 1	0.017	Zebrafish
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.017
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.017
APOC2	apolipoprotein C-II	0.017
SH2D2A	SH2 domain containing 2A	0.017
F13A1	coagulation factor XIII, A1 polypeptide	0.016
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.016
PLTP	phospholipid transfer protein	0.016
CD2	CD2 molecule	0.016
SRCIN1	SRC kinase signaling inhibitor 1	0.016
EDNRB	endothelin receptor type B	0.016
IL2RG	interleukin 2 receptor, gamma	0.016
CCL21	chemokine (C-C motif) ligand 21	0.016
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.016
ZNF100	zinc finger protein 100	0.016	Human
C7orf64	chromosome 7 open reading frame 64	0.016
C3	complement component 3	0.016
PLCG1	phospholipase C, gamma 1	0.016
MARCO	macrophage receptor with collagenous structure	0.016
ZNF506	zinc finger protein 506	0.015	Human
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.015
EHD2	EH-domain containing 2	0.015
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.015
PTRF	polymerase I and transcript release factor	0.015
MYD88	myeloid differentiation primary response gene (88)	0.015
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.015
ARRB1	arrestin, beta 1	0.015
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.015
CD22	CD22 molecule	0.015
INADL	InaD-like (Drosophila)	0.015
C1S	complement component 1, s subcomponent	0.015
APOA2	apolipoprotein A-II	0.014
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.014
ZNF138	zinc finger protein 138	0.014
PI3	peptidase inhibitor 3, skin-derived	0.014
LTBP4	latent transforming growth factor beta binding protein 4	0.014
CD48	CD48 molecule	0.014
FAM83C	family with sequence similarity 83, member C	0.014
ITGA1	integrin, alpha 1	0.014
GRB10	growth factor receptor-bound protein 10	0.014
IRF4	interferon regulatory factor 4	0.014
PPARG	peroxisome proliferator-activated receptor gamma	0.014
NSF	N-ethylmaleimide-sensitive factor	0.014
ZNF260	zinc finger protein 260	0.014
DCN	decorin	0.013
KCNRG	potassium channel regulator	0.013
IL18R1	interleukin 18 receptor 1	0.013
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.013
CD209	CD209 molecule	0.013
CLEC7A	C-type lectin domain family 7, member A	0.013
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.013
AQP9	aquaporin 9	0.013
BCL2A1	BCL2-related protein A1	0.013
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.013
ZNF347	zinc finger protein 347	0.013
GPR84	G protein-coupled receptor 84	0.013
AOAH	acyloxyacyl hydrolase (neutrophil)	0.013
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.013
LBP	lipopolysaccharide binding protein	0.013
TREM1	triggering receptor expressed on myeloid cells 1	0.013
NCOR1	nuclear receptor corepressor 1	0.012
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.012
FST	follistatin	0.012
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.012
SLC15A3	solute carrier family 15, member 3	0.012
TYMP	thymidine phosphorylase	0.012
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.012
GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.012
TGFA	transforming growth factor, alpha	0.012
BCAR1	breast cancer anti-estrogen resistance 1	0.012
C2	complement component 2	0.012
TPSB2	tryptase beta 2 (gene/pseudogene)	0.012
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.012
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.012	Human
ZNF567	zinc finger protein 567	0.012
ALB	albumin	0.012
CSF1	colony stimulating factor 1 (macrophage)	0.012
CXCR3	chemokine (C-X-C motif) receptor 3	0.012
GBP1	guanylate binding protein 1, interferon-inducible	0.012
NLRP3	NLR family, pyrin domain containing 3	0.012	Human
ZNF136	zinc finger protein 136	0.012
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.012
KRT81	keratin 81	0.011
PELI1	pellino homolog 1 (Drosophila)	0.011
IVL	involucrin	0.011
ANXA7	annexin A7	0.011
DPT	dermatopontin	0.011
TRPV6	transient receptor potential cation channel, subfamily V, member 6	0.011
RFX7	regulatory factor X, 7	0.011
RBAK	RB-associated KRAB zinc finger	0.011
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.011
C1R	complement component 1, r subcomponent	0.011
IL18BP	interleukin 18 binding protein	0.011
PRDM1	PR domain containing 1, with ZNF domain	0.011
XCL2	chemokine (C motif) ligand 2	0.011
IDO1	indoleamine 2,3-dioxygenase 1	0.011
EMILIN1	elastin microfibril interfacer 1	0.011
ZNF665	zinc finger protein 665	0.011
ZNF480	zinc finger protein 480	0.011
CXCL3	chemokine (C-X-C motif) ligand 3	0.011
GPR171	G protein-coupled receptor 171	0.011
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.011
FASLG	Fas ligand (TNF superfamily, member 6)	0.011
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.011
IL2RA	interleukin 2 receptor, alpha	0.011
AVPR2	arginine vasopressin receptor 2	0.011
CCL23	chemokine (C-C motif) ligand 23	0.010	Human
PLEK	pleckstrin	0.010
MMP19	matrix metallopeptidase 19	0.010
SAA2	serum amyloid A2	0.010
PRMT6	protein arginine methyltransferase 6	0.010
DUSP7	dual specificity phosphatase 7	0.010
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.010
APOB	apolipoprotein B (including Ag(x) antigen)	0.010
NMI	N-myc (and STAT) interactor	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010
SIGLEC7	sialic acid binding Ig-like lectin 7	0.010
IRAK3	interleukin-1 receptor-associated kinase 3	0.010
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.010
TREM2	triggering receptor expressed on myeloid cells 2	0.010
ZNF813	zinc finger protein 813	0.010