IMP

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Homo sapiens

28 genes annotated in human

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membrane budding

GO:0006900

The evagination of a membrane, resulting in formation of a vesicle.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "membrane budding"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "membrane budding" (in gray)

Name	Description	Probability	Func Analog Organism
PDCD6IP	programmed cell death 6 interacting protein	0.999
TSG101	tumor susceptibility gene 101	0.998
EPS15	epidermal growth factor receptor pathway substrate 15	0.997
S100A6	S100 calcium binding protein A6	0.989	Human
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.986	Yeast
PDCD6	programmed cell death 6	0.982
SEC23A	Sec23 homolog A (S. cerevisiae)	0.974	Yeast
CUL3	cullin 3	0.963
S100A9	S100 calcium binding protein A9	0.958	Human
STON2	stonin 2	0.954
S100A8	S100 calcium binding protein A8	0.861	Human
LGALS1	lectin, galactoside-binding, soluble, 1	0.849
DNM2	dynamin 2	0.835	Fly
S100A10	S100 calcium binding protein A10	0.814
ANXA2	annexin A2	0.810
SH3KBP1	SH3-domain kinase binding protein 1	0.752
S100A11	S100 calcium binding protein A11	0.735	Human
SOS1	son of sevenless homolog 1 (Drosophila)	0.727
ANXA1	annexin A1	0.695	Human
ITSN1	intersectin 1 (SH3 domain protein)	0.688	Human
ARF4	ADP-ribosylation factor 4	0.642
DAAM1	dishevelled associated activator of morphogenesis 1	0.599
IQGAP1	IQ motif containing GTPase activating protein 1	0.546
S100B	S100 calcium binding protein B	0.501	Human
COPB1	coatomer protein complex, subunit beta 1	0.480
FASLG	Fas ligand (TNF superfamily, member 6)	0.466
CLTC	clathrin, heavy chain (Hc)	0.457
USP54	ubiquitin specific peptidase 54	0.439
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.402
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.388
SEC24A	SEC24 family, member A (S. cerevisiae)	0.373
CHMP1A	chromatin modifying protein 1A	0.370
SEC31A	SEC31 homolog A (S. cerevisiae)	0.355	Yeast
DAPK1	death-associated protein kinase 1	0.335
S100A4	S100 calcium binding protein A4	0.313	Human
ARCN1	archain 1	0.236
AGFG1	ArfGAP with FG repeats 1	0.235
S100A1	S100 calcium binding protein A1	0.233	Human
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.226
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.224
NBR1	neighbor of BRCA1 gene 1	0.221
SQLE	squalene epoxidase	0.219
CHMP4B	chromatin modifying protein 4B	0.213
WIPF1	WAS/WASL interacting protein family, member 1	0.211
OCRL	oculocerebrorenal syndrome of Lowe	0.196
USP8	ubiquitin specific peptidase 8	0.194	Yeast
ANXA7	annexin A7	0.168	Human
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.165
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.158
GOLGA2	golgin A2	0.152
KRT15	keratin 15	0.151
SURF4	surfeit 4	0.150
GOLGA5	golgin A5	0.149
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.148
CAST	calpastatin	0.143
SEC24B	SEC24 family, member B (S. cerevisiae)	0.131	Yeast Mouse
ARFGAP2	ADP-ribosylation factor GTPase activating protein 2	0.120
DNM1	dynamin 1	0.117	Fly
AREG	amphiregulin	0.116
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.115
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.114
BCAR1	breast cancer anti-estrogen resistance 1	0.110
WNK4	WNK lysine deficient protein kinase 4	0.109
S100A2	S100 calcium binding protein A2	0.104	Human
ABI1	abl-interactor 1	0.104
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.103
RNF111	ring finger protein 111	0.100
BTBD10	BTB (POZ) domain containing 10	0.099
CHMP1B	chromatin modifying protein 1B	0.091
RAB2A	RAB2A, member RAS oncogene family	0.091
SEC13	SEC13 homolog (S. cerevisiae)	0.090	Yeast
IDI1	isopentenyl-diphosphate delta isomerase 1	0.088
SPOP	speckle-type POZ protein	0.087
PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	0.086
TMED7	transmembrane emp24 protein transport domain containing 7	0.085
SC4MOL	sterol-C4-methyl oxidase-like	0.084
STAMBP	STAM binding protein	0.084
SMN1	survival of motor neuron 1, telomeric	0.082
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.072
CHMP2B	chromatin modifying protein 2B	0.071
SH3GL1	SH3-domain GRB2-like 1	0.065
GORAB	golgin, RAB6-interacting	0.062
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.059
WASL	Wiskott-Aldrich syndrome-like	0.058	Rat Fly
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.058
ANXA5	annexin A5	0.057	Human
STARD4	StAR-related lipid transfer (START) domain containing 4	0.056
S100P	S100 calcium binding protein P	0.056	Human
TNK2	tyrosine kinase, non-receptor, 2	0.054
KLC1	kinesin light chain 1	0.054
RNF11	ring finger protein 11	0.053
SEC24D	SEC24 family, member D (S. cerevisiae)	0.052	Yeast
RAB5A	RAB5A, member RAS oncogene family	0.051
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.051
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.051
FCHO2	FCH domain only 2	0.051
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.050
SNX9	sorting nexin 9	0.049
KRT19	keratin 19	0.049
MYO6	myosin VI	0.049
COPA	coatomer protein complex, subunit alpha	0.048
SNAP25	synaptosomal-associated protein, 25kDa	0.048
SEC24C	SEC24 family, member C (S. cerevisiae)	0.044	Yeast
SH3GL2	SH3-domain GRB2-like 2	0.044
COPG	coatomer protein complex, subunit gamma	0.042
TMED2	transmembrane emp24 domain trafficking protein 2	0.042
RAB6C	RAB6C, member RAS oncogene family	0.041
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.041
RAB1A	RAB1A, member RAS oncogene family	0.041
NMT2	N-myristoyltransferase 2	0.041
SERINC1	serine incorporator 1	0.040
ATXN1	ataxin 1	0.040
TOM1L1	target of myb1 (chicken)-like 1	0.040
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.039	Rat
RPS27L	ribosomal protein S27-like	0.039
CLIC1	chloride intracellular channel 1	0.037
FNDC3B	fibronectin type III domain containing 3B	0.036
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	0.035
ARHGAP31	Rho GTPase activating protein 31	0.034
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.034
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.034
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.034
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.033
SELS	selenoprotein S	0.032
ITSN2	intersectin 2	0.032	Human
CLTCL1	clathrin, heavy chain-like 1	0.031
RUSC2	RUN and SH3 domain containing 2	0.030
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.030
ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	0.030
ADAM9	ADAM metallopeptidase domain 9	0.030
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.030
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.030
AGER	advanced glycosylation end product-specific receptor	0.029
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.029
NUMB	numb homolog (Drosophila)	0.029
RAB6A	RAB6A, member RAS oncogene family	0.029
CLIC4	chloride intracellular channel 4	0.029
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.029
TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.029
S100A12	S100 calcium binding protein A12	0.029	Human
STX7	syntaxin 7	0.029
CD2AP	CD2-associated protein	0.028
EMP1	epithelial membrane protein 1	0.028
SDCBP	syndecan binding protein (syntenin)	0.028
FYN	FYN oncogene related to SRC, FGR, YES	0.027
ALG2	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)	0.027
CHMP5	chromatin modifying protein 5	0.026
LGALS3	lectin, galactoside-binding, soluble, 3	0.026
RAB11A	RAB11A, member RAS oncogene family	0.026
VPS4B	vacuolar protein sorting 4 homolog B (S. cerevisiae)	0.026
HTT	huntingtin	0.026
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.026
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.026
ACTR10	actin-related protein 10 homolog (S. cerevisiae)	0.025
ACBD3	acyl-CoA binding domain containing 3	0.025
KLHL2	kelch-like 2, Mayven (Drosophila)	0.025	Human
SFN	stratifin	0.024
MED12	mediator complex subunit 12	0.022
NCF2	neutrophil cytosolic factor 2	0.022
DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	0.022
RBM45	RNA binding motif protein 45	0.021
TMSB10	thymosin beta 10	0.021
ANXA3	annexin A3	0.020
GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	0.020
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.020
NECAP2	NECAP endocytosis associated 2	0.020
USP20	ubiquitin specific peptidase 20	0.020
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.019
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.019
LMO4	LIM domain only 4	0.019
RHOA	ras homolog gene family, member A	0.019
AP1B1	adaptor-related protein complex 1, beta 1 subunit	0.019	Rat
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.018
SH3BP4	SH3-domain binding protein 4	0.018
NCKAP1	NCK-associated protein 1	0.018
SNX2	sorting nexin 2	0.018
PEF1	penta-EF-hand domain containing 1	0.018
RAB7A	RAB7A, member RAS oncogene family	0.018
WASF2	WAS protein family, member 2	0.018
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.018
MED28	mediator complex subunit 28	0.018
SGMS1	sphingomyelin synthase 1	0.018
NRBF2	nuclear receptor binding factor 2	0.017
CKAP4	cytoskeleton-associated protein 4	0.017
SWAP70	SWAP switching B-cell complex 70kDa subunit	0.017
UBA1	ubiquitin-like modifier activating enzyme 1	0.017
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.016
USP9X	ubiquitin specific peptidase 9, X-linked	0.016
FMNL1	formin-like 1	0.016
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.016
CSTA	cystatin A (stefin A)	0.016
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.016
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.015
CTTN	cortactin	0.015
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.015
SRPK2	SRSF protein kinase 2	0.015
SYNJ2	synaptojanin 2	0.015	Worm
MYOF	myoferlin	0.015
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.015
PFN2	profilin 2	0.015
SSFA2	sperm specific antigen 2	0.014
UFC1	ubiquitin-fold modifier conjugating enzyme 1	0.014
PAK7	p21 protein (Cdc42/Rac)-activated kinase 7	0.014
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.014
NCKAP1L	NCK-associated protein 1-like	0.014
TACC1	transforming, acidic coiled-coil containing protein 1	0.014
PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.014
SEC61B	Sec61 beta subunit	0.014
ITGB5	integrin, beta 5	0.014
DCTN6	dynactin 6	0.014
SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	0.014
IQGAP2	IQ motif containing GTPase activating protein 2	0.013
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.013
FXR2	fragile X mental retardation, autosomal homolog 2	0.013
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	0.013
CD46	CD46 molecule, complement regulatory protein	0.013
CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	0.013
TRIP10	thyroid hormone receptor interactor 10	0.013	Human
TMED9	transmembrane emp24 protein transport domain containing 9	0.013
EPS8	epidermal growth factor receptor pathway substrate 8	0.013
MTMR6	myotubularin related protein 6	0.013
OPTN	optineurin	0.013
GMPPA	GDP-mannose pyrophosphorylase A	0.013
PCDHA4	protocadherin alpha 4	0.013
DPP3	dipeptidyl-peptidase 3	0.013
MED16	mediator complex subunit 16	0.013
FKBP4	FK506 binding protein 4, 59kDa	0.013
SPOPL	speckle-type POZ protein-like	0.013
RAB14	RAB14, member RAS oncogene family	0.013
CD59	CD59 molecule, complement regulatory protein	0.013
RYBP	RING1 and YY1 binding protein	0.013
SLC35A1	solute carrier family 35 (CMP-sialic acid transporter), member A1	0.013
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.013
RRM2B	ribonucleotide reductase M2 B (TP53 inducible)	0.013
FN1	fibronectin 1	0.013
CHMP4C	chromatin modifying protein 4C	0.013	Human
PRUNE	prune homolog (Drosophila)	0.012
MEA1	male-enhanced antigen 1	0.012
MAP4	microtubule-associated protein 4	0.012
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.012
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.012
EXOC1	exocyst complex component 1	0.012
RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	0.012
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.012
GOLGB1	golgin B1	0.012
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.012
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.012
TMEM214	transmembrane protein 214	0.012
AP2A2	adaptor-related protein complex 2, alpha 2 subunit	0.012
SLC35A4	solute carrier family 35, member A4	0.012
TEKT4	tektin 4	0.012
ACSL3	acyl-CoA synthetase long-chain family member 3	0.012
SH3GL3	SH3-domain GRB2-like 3	0.012
CSNK1A1	casein kinase 1, alpha 1	0.012
MTF1	metal-regulatory transcription factor 1	0.012
BMP2K	BMP2 inducible kinase	0.011
NPC2	Niemann-Pick disease, type C2	0.011
BAIAP2	BAI1-associated protein 2	0.011
CAPG	capping protein (actin filament), gelsolin-like	0.011
ALDH3A2	aldehyde dehydrogenase 3 family, member A2	0.011
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.011
WDR47	WD repeat domain 47	0.011
SQSTM1	sequestosome 1	0.011
MAPK6	mitogen-activated protein kinase 6	0.011
TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like	0.011
SERP1	stress-associated endoplasmic reticulum protein 1	0.011
CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	0.011
CABIN1	calcineurin binding protein 1	0.011
COPE	coatomer protein complex, subunit epsilon	0.011
SNX33	sorting nexin 33	0.011
ZNF217	zinc finger protein 217	0.011
UBQLN2	ubiquilin 2	0.011
NPTN	neuroplastin	0.011
CHMP6	chromatin modifying protein 6	0.011	Yeast
LDLR	low density lipoprotein receptor	0.011
PFDN1	prefoldin subunit 1	0.011
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.010
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.010
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.010
FAM50A	family with sequence similarity 50, member A	0.010
SRP68	signal recognition particle 68kDa	0.010
CSNK1D	casein kinase 1, delta	0.010
KIAA1377	KIAA1377	0.010
CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	0.010
MYL12B	myosin, light chain 12B, regulatory	0.010
RDBP	RD RNA binding protein	0.010