IMP

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Mus musculus

4 genes annotated in mouse

Multi-species View

regulation of ral gtpase activity

GO:0032315

Any process that modulates the activity of a GTPase of the Ral family.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of ral gtpase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of ral gtpase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Ldb3	LIM domain binding 3	0.694
Vhl	von Hippel-Lindau tumor suppressor	0.646
Akt1	thymoma viral proto-oncogene 1	0.578	Mouse
Akt2	thymoma viral proto-oncogene 2	0.441
Prkce	protein kinase C, epsilon	0.281
Ilk	integrin linked kinase	0.248
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.224
Mapkap1	mitogen-activated protein kinase associated protein 1	0.215
Cd28	CD28 antigen	0.204
Vegfa	vascular endothelial growth factor A	0.198
Igh	immunoglobulin heavy chain complex	0.175
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.164
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.157
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.155
Bcl2	B-cell leukemia/lymphoma 2	0.153
Blnk	B-cell linker	0.144
Flii	flightless I homolog (Drosophila)	0.126
Rasal1	RAS protein activator like 1 (GAP1 like)	0.124
Kctd20	potassium channel tetramerisation domain containing 20	0.123
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.122
Prkcb	protein kinase C, beta	0.106
Actn2	actinin alpha 2	0.100
Cd151	CD151 antigen	0.097
Add1	adducin 1 (alpha)	0.097
Rap1gap	Rap1 GTPase-activating protein	0.085
Homer1	homer homolog 1 (Drosophila)	0.081
Plxnd1	plexin D1	0.078
Plxna1	plexin A1	0.074
Pparg	peroxisome proliferator activated receptor gamma	0.072
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.064
Capn1	calpain 1	0.062
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.061
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.061
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.056
Mapkapk2	MAP kinase-activated protein kinase 2	0.052
Kif3b	kinesin family member 3B	0.051
Arhgap1	Rho GTPase activating protein 1	0.048
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.048
Plekho1	pleckstrin homology domain containing, family O member 1	0.048
Prkca	protein kinase C, alpha	0.046
Igf1r	insulin-like growth factor I receptor	0.044
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.042
Adrbk1	adrenergic receptor kinase, beta 1	0.042
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.041
Sirpa	signal-regulatory protein alpha	0.041
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.040
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.040
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.039
Trim46	tripartite motif-containing 46	0.039
Ate1	arginyltransferase 1	0.039
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.039
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.038
Plcb1	phospholipase C, beta 1	0.038
Gna12	guanine nucleotide binding protein, alpha 12	0.037
Hpcal4	hippocalcin-like 4	0.036
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.036
Cdk14	cyclin-dependent kinase 14	0.036
Csnk1g2	casein kinase 1, gamma 2	0.034
Actn4	actinin alpha 4	0.034
Sipa1	signal-induced proliferation associated gene 1	0.034
Tgfbr1	transforming growth factor, beta receptor I	0.034
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.033
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.032
Gramd1a	GRAM domain containing 1A	0.032
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.032
Man1a2	mannosidase, alpha, class 1A, member 2	0.031
Rasgrp1	RAS guanyl releasing protein 1	0.031
Srgap2	SLIT-ROBO Rho GTPase activating protein 2	0.031
Glt25d1	glycosyltransferase 25 domain containing 1	0.031
Shank2	SH3/ankyrin domain gene 2	0.030
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.030
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.030
Pygo2	pygopus 2	0.030
Gsk3b	glycogen synthase kinase 3 beta	0.030
Atp13a2	ATPase type 13A2	0.029
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.029
Arc	activity regulated cytoskeletal-associated protein	0.028
Plekho2	pleckstrin homology domain containing, family O member 2	0.028
Ahi1	Abelson helper integration site 1	0.028
Braf	Braf transforming gene	0.028
Coro1c	coronin, actin binding protein 1C	0.027
Acbd3	acyl-Coenzyme A binding domain containing 3	0.027
Sec14l1	SEC14-like 1 (S. cerevisiae)	0.027
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.027
Cd19	CD19 antigen	0.026
Atp11c	ATPase, class VI, type 11C	0.026
Git1	G protein-coupled receptor kinase-interactor 1	0.026
Ldb1	LIM domain binding 1	0.025
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.025
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.025
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.025
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.025
Cic	capicua homolog (Drosophila)	0.025
L1cam	L1 cell adhesion molecule	0.025
Dnm1	dynamin 1	0.025
Stub1	STIP1 homology and U-Box containing protein 1	0.025
Klc1	kinesin light chain 1	0.024
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.024
Src	Rous sarcoma oncogene	0.024
Nphs2	nephrosis 2 homolog, podocin (human)	0.024
Trim35	tripartite motif-containing 35	0.023
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.023
Prkcd	protein kinase C, delta	0.023	Mouse
Tmem189	transmembrane protein 189	0.022
Scrg1	scrapie responsive gene 1	0.022
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.022
Parp6	poly (ADP-ribose) polymerase family, member 6	0.022
Zfp513	zinc finger protein 513	0.022
Usp12	ubiquitin specific peptidase 12	0.021
Gtpbp2	GTP binding protein 2	0.021
Mgat4b	mannoside acetylglucosaminyltransferase 4, isoenzyme B	0.021
Npepl1	aminopeptidase-like 1	0.021
Sh2b3	SH2B adaptor protein 3	0.021
Slc12a5	solute carrier family 12, member 5	0.021
Mbp	myelin basic protein	0.021
Fas	Fas (TNF receptor superfamily member 6)	0.021
Ltbr	lymphotoxin B receptor	0.021
Pitpnm1	phosphatidylinositol transfer protein, membrane-associated 1	0.021
Vasp	vasodilator-stimulated phosphoprotein	0.020
Sh3kbp1	SH3-domain kinase binding protein 1	0.020
Gpc1	glypican 1	0.020
Limk2	LIM motif-containing protein kinase 2	0.020
Mark2	MAP/microtubule affinity-regulating kinase 2	0.020
Pacs2	phosphofurin acidic cluster sorting protein 2	0.020
Rgs11	regulator of G-protein signaling 11	0.020
Mtmr1	myotubularin related protein 1	0.020
Ctdnep1	CTD nuclear envelope phosphatase 1	0.019
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.019
Dctn1	dynactin 1	0.019
Ikzf3	IKAROS family zinc finger 3	0.019
Cpd	carboxypeptidase D	0.019
Hdac7	histone deacetylase 7	0.019
Zfp740	zinc finger protein 740	0.019
Mapk14	mitogen-activated protein kinase 14	0.019
Kctd10	potassium channel tetramerisation domain containing 10	0.019
Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1	0.019
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.019
Sav1	salvador homolog 1 (Drosophila)	0.018
Sort1	sortilin 1	0.018
Faah	fatty acid amide hydrolase	0.018
Pea15a	phosphoprotein enriched in astrocytes 15A	0.018
Myo1c	myosin IC	0.018
Sorl1	sortilin-related receptor, LDLR class A repeats-containing	0.018
Dlg3	discs, large homolog 3 (Drosophila)	0.018
Copg	coatomer protein complex, subunit gamma	0.018
Kif1b	kinesin family member 1B	0.018
Btbd10	BTB (POZ) domain containing 10	0.018
Leng8	leukocyte receptor cluster (LRC) member 8	0.018
Evl	Ena-vasodilator stimulated phosphoprotein	0.017
Pfkl	phosphofructokinase, liver, B-type	0.017
Extl3	exostoses (multiple)-like 3	0.017
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.017
1700081L11Rik	RIKEN cDNA 1700081L11 gene	0.017
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.017
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.017
St6galnac4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	0.017
Mapk3	mitogen-activated protein kinase 3	0.017
Tubb4	tubulin, beta 4	0.017
Lyst	lysosomal trafficking regulator	0.017
Atp8b2	ATPase, class I, type 8B, member 2	0.017
Kifc2	kinesin family member C2	0.016
Ptk2	PTK2 protein tyrosine kinase 2	0.016
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.016
Cerk	ceramide kinase	0.016
Abhd14b	abhydrolase domain containing 14b	0.016
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.016
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.016
Akap8l	A kinase (PRKA) anchor protein 8-like	0.016
Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	0.016
Trim8	tripartite motif-containing 8	0.016
Dgcr2	DiGeorge syndrome critical region gene 2	0.016
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.016
Abca2	ATP-binding cassette, sub-family A (ABC1), member 2	0.016
Arf3	ADP-ribosylation factor 3	0.015
Arl4c	ADP-ribosylation factor-like 4C	0.015
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.015
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.015
Egln1	EGL nine homolog 1 (C. elegans)	0.015
Dact3	dapper homolog 3, antagonist of beta-catenin (xenopus)	0.015
Pex5	peroxisomal biogenesis factor 5	0.015
Capn5	calpain 5	0.015
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.015
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.015
Mtap7	microtubule-associated protein 7	0.015
Rnf10	ring finger protein 10	0.015
Hspa4l	heat shock protein 4 like	0.015
Akap10	A kinase (PRKA) anchor protein 10	0.015
Ltk	leukocyte tyrosine kinase	0.015
Ddhd1	DDHD domain containing 1	0.015
Dgka	diacylglycerol kinase, alpha	0.015
Ncor2	nuclear receptor co-repressor 2	0.015
Vav3	vav 3 oncogene	0.015
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.015
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.015
Rims2	regulating synaptic membrane exocytosis 2	0.015
Ankrd16	ankyrin repeat domain 16	0.015
Ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.015
Med12	mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)	0.014
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.014
Nptx1	neuronal pentraxin 1	0.014
Grb2	growth factor receptor bound protein 2	0.014
Crb2	crumbs homolog 2 (Drosophila)	0.014
Dlg4	discs, large homolog 4 (Drosophila)	0.014
Csnk1e	casein kinase 1, epsilon	0.014
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.014
Adam10	a disintegrin and metallopeptidase domain 10	0.014
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.014
Dlg2	discs, large homolog 2 (Drosophila)	0.014
Foxo1	forkhead box O1	0.014
Bag6	BCL2-associated athanogene 6	0.014
Polk	polymerase (DNA directed), kappa	0.014
Map4k5	mitogen-activated protein kinase kinase kinase kinase 5	0.014
4933411K20Rik	RIKEN cDNA 4933411K20 gene	0.014
Trim11	tripartite motif-containing 11	0.014
Lrrc45	leucine rich repeat containing 45	0.014
Abr	active BCR-related gene	0.014
Ctnnd1	catenin (cadherin associated protein), delta 1	0.014
BC037034	cDNA sequence BC037034	0.014
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.013
Klf7	Kruppel-like factor 7 (ubiquitous)	0.013
Dtx1	deltex 1 homolog (Drosophila)	0.013
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.013
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.013
Mgrn1	mahogunin, ring finger 1	0.013
Zfp692	zinc finger protein 692	0.013
Grb7	growth factor receptor bound protein 7	0.013
Raf1	v-raf-leukemia viral oncogene 1	0.013
Irf3	interferon regulatory factor 3	0.013
C230081A13Rik	RIKEN cDNA C230081A13 gene	0.013
Tspan2	tetraspanin 2	0.013
Wrn	Werner syndrome homolog (human)	0.013
Mprip	myosin phosphatase Rho interacting protein	0.013
Ptov1	prostate tumor over expressed gene 1	0.013
Clcn6	chloride channel 6	0.013
Itga3	integrin alpha 3	0.013
Frmd8	FERM domain containing 8	0.013
Rassf2	Ras association (RalGDS/AF-6) domain family member 2	0.013
Trim44	tripartite motif-containing 44	0.013
Pla2g6	phospholipase A2, group VI	0.013
Efhd1	EF hand domain containing 1	0.013
Gmip	Gem-interacting protein	0.013
Tbc1d20	TBC1 domain family, member 20	0.013
Stx2	syntaxin 2	0.013
Usp22	ubiquitin specific peptidase 22	0.013
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.012
Dgke	diacylglycerol kinase, epsilon	0.012
Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	0.012
Cux1	cut-like homeobox 1	0.012
Adcy6	adenylate cyclase 6	0.012
Ssbp4	single stranded DNA binding protein 4	0.012
Akap5	A kinase (PRKA) anchor protein 5	0.012
Cdc42se1	CDC42 small effector 1	0.012
Ehd3	EH-domain containing 3	0.012
Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	0.012
Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.012
Pllp	plasma membrane proteolipid	0.012
Fam171a1	family with sequence similarity 171, member A1	0.012
Ugt8a	UDP galactosyltransferase 8A	0.012
Slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.012
Polg	polymerase (DNA directed), gamma	0.012
Slc22a23	solute carrier family 22, member 23	0.012
Ptprj	protein tyrosine phosphatase, receptor type, J	0.012
Mapt	microtubule-associated protein tau	0.012
Gtf3c1	general transcription factor III C 1	0.012
Slc4a2	solute carrier family 4 (anion exchanger), member 2	0.012
Rnf208	ring finger protein 208	0.012
Jhdm1d	jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)	0.012
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.012
Ctr9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.012
Sepn1	selenoprotein N, 1	0.012
Pacs1	phosphofurin acidic cluster sorting protein 1	0.012
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.012
Mapk9	mitogen-activated protein kinase 9	0.012
Klc2	kinesin light chain 2	0.011
Irf4	interferon regulatory factor 4	0.011
Usp5	ubiquitin specific peptidase 5 (isopeptidase T)	0.011
Znrf1	zinc and ring finger 1	0.011
Mlf2	myeloid leukemia factor 2	0.011
Rictor	RPTOR independent companion of MTOR, complex 2	0.011
Lemd2	LEM domain containing 2	0.011
Car4	carbonic anhydrase 4	0.011
Tle2	transducin-like enhancer of split 2, homolog of Drosophila E(spl)	0.011
Lmna	lamin A	0.011
Myo5b	myosin VB	0.011
Stard3	START domain containing 3	0.011
Gpr56	G protein-coupled receptor 56	0.011
Npas2	neuronal PAS domain protein 2	0.011
Pim2	proviral integration site 2	0.011
Dusp7	dual specificity phosphatase 7	0.011
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.011
Adcy1	adenylate cyclase 1	0.011
Ckap5	cytoskeleton associated protein 5	0.011
Arrb2	arrestin, beta 2	0.011
Kif3a	kinesin family member 3A	0.011
Sept9	septin 9	0.011
Plp1	proteolipid protein (myelin) 1	0.011
Gtf2i	general transcription factor II I	0.011
Cttnbp2nl	CTTNBP2 N-terminal like	0.011
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.011
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.011
Csrp1	cysteine and glycine-rich protein 1	0.011
Mtap2	microtubule-associated protein 2	0.011
Elmo2	engulfment and cell motility 2, ced-12 homolog (C. elegans)	0.011
Bsn	bassoon	0.011
Hip1r	huntingtin interacting protein 1 related	0.011
Arrb1	arrestin, beta 1	0.011
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.011
Eif2c3	eukaryotic translation initiation factor 2C, 3	0.011
Mtmr3	myotubularin related protein 3	0.011
Scd1	stearoyl-Coenzyme A desaturase 1	0.011
Pxn	paxillin	0.011
Fam48a	family with sequence similarity 48, member A	0.011
Rab2b	RAB2B, member RAS oncogene family	0.011
Ncln	nicalin homolog (zebrafish)	0.011
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.011
Creb1	cAMP responsive element binding protein 1	0.011
Agtpbp1	ATP/GTP binding protein 1	0.011
Elmo1	engulfment and cell motility 1, ced-12 homolog (C. elegans)	0.011
Itpk1	inositol 1,3,4-triphosphate 5/6 kinase	0.011
Slain1	SLAIN motif family, member 1	0.011
Pip5k1b	phosphatidylinositol-4-phosphate 5-kinase, type 1 beta	0.010
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.010
Arhgap17	Rho GTPase activating protein 17	0.010
Trpc1	transient receptor potential cation channel, subfamily C, member 1	0.010
Cish	cytokine inducible SH2-containing protein	0.010
Stxbp5	syntaxin binding protein 5 (tomosyn)	0.010
Myo9b	myosin IXb	0.010
Itpka	inositol 1,4,5-trisphosphate 3-kinase A	0.010
Cd99	CD99 antigen	0.010
Pcbp4	poly(rC) binding protein 4	0.010
Ttyh3	tweety homolog 3 (Drosophila)	0.010
Sdccag8	serologically defined colon cancer antigen 8	0.010
Man2c1	mannosidase, alpha, class 2C, member 1	0.010
Cd40	CD40 antigen	0.010
Nrbp2	nuclear receptor binding protein 2	0.010
Lats1	large tumor suppressor	0.010
Osbpl6	oxysterol binding protein-like 6	0.010
Zfp445	zinc finger protein 445	0.010
4732418C07Rik	RIKEN cDNA 4732418C07 gene	0.010