IMP

Process View

Mus musculus

19 genes annotated in mouse

somatic stem cell division

The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "somatic stem cell division"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "somatic stem cell division" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.938
Gli3	GLI-Kruppel family member GLI3	0.842
Ctnnb1	catenin (cadherin associated protein), beta 1	0.689
Pax2	paired box gene 2	0.649
Wnt3a	wingless-related MMTV integration site 3A	0.567
Hoxb3	homeobox B3	0.539
Hoxa1	homeobox A1	0.526
Sox2	SRY-box containing gene 2	0.509
Lef1	lymphoid enhancer binding factor 1	0.496
Hoxb6	homeobox B6	0.461	Mouse
Rnf2	ring finger protein 2	0.416
Dll1	delta-like 1 (Drosophila)	0.411
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.401
Hoxd9	homeobox D9	0.384
Ptk7	PTK7 protein tyrosine kinase 7	0.366
Wnt5a	wingless-related MMTV integration site 5A	0.328	Mouse
Hoxb5	homeobox B5	0.315	Mouse
Shh	sonic hedgehog	0.290
Hoxa5	homeobox A5	0.282	Mouse
Hoxa2	homeobox A2	0.281
Tbx3	T-box 3	0.274
Rybp	RING1 and YY1 binding protein	0.248
Hoxa10	homeobox A10	0.240
App	amyloid beta (A4) precursor protein	0.206
Axin1	axin 1	0.192
Hoxc5	homeobox C5	0.179	Mouse
Hoxc9	homeobox C9	0.171
Pax8	paired box gene 8	0.162
Esr1	estrogen receptor 1 (alpha)	0.158
Gli1	GLI-Kruppel family member GLI1	0.135
Twist2	twist homolog 2 (Drosophila)	0.133
Pou3f3	POU domain, class 3, transcription factor 3	0.132
Rarg	retinoic acid receptor, gamma	0.127
Hoxc6	homeobox C6	0.127	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.124
Psen1	presenilin 1	0.124
Bmp4	bone morphogenetic protein 4	0.122
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.119
Fzd8	frizzled homolog 8 (Drosophila)	0.119	Mouse
Hoxd11	homeobox D11	0.107
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.106	Worm
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.102
Lrp6	low density lipoprotein receptor-related protein 6	0.099
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.091
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.087
Dlg4	discs, large homolog 4 (Drosophila)	0.086
Tbx2	T-box 2	0.086
Meox2	mesenchyme homeobox 2	0.085
Lama5	laminin, alpha 5	0.084
Hoxb4	homeobox B4	0.081
Gata3	GATA binding protein 3	0.080
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.077	Mouse
Hoxd8	homeobox D8	0.077	Mouse
Gas1	growth arrest specific 1	0.074
Fgf10	fibroblast growth factor 10	0.073	Mouse
Rara	retinoic acid receptor, alpha	0.072
Gdnf	glial cell line derived neurotrophic factor	0.072
Prrx2	paired related homeobox 2	0.072
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.067
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.065
Rarb	retinoic acid receptor, beta	0.064
Notch2	Notch gene homolog 2 (Drosophila)	0.062	Mouse
Hoxa11	homeobox A11	0.062
Lep	leptin	0.061
Ar	androgen receptor	0.061
Hoxa4	homeobox A4	0.061	Mouse
Wnt4	wingless-related MMTV integration site 4	0.060	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.058
Trp63	transformation related protein 63	0.058
Gopc	golgi associated PDZ and coiled-coil motif containing	0.058
Fzd1	frizzled homolog 1 (Drosophila)	0.057	Mouse
Pax3	paired box gene 3	0.057
Fgf2	fibroblast growth factor 2	0.056	Mouse
Gpc3	glypican 3	0.055
Emid2	EMI domain containing 2	0.055
Gli2	GLI-Kruppel family member GLI2	0.053
Hic1	hypermethylated in cancer 1	0.053
Pbx1	pre B-cell leukemia transcription factor 1	0.052
Dlx5	distal-less homeobox 5	0.052
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.051	Worm
Msx2	homeobox, msh-like 2	0.049
Vangl2	vang-like 2 (van gogh, Drosophila)	0.048
Hoxd4	homeobox D4	0.047	Mouse
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.046
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.045
Gdf11	growth differentiation factor 11	0.044	Mouse
Phc2	polyhomeotic-like 2 (Drosophila)	0.044
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.044
Bcl2	B-cell leukemia/lymphoma 2	0.042
Cbx7	chromobox homolog 7	0.042
Tead3	TEA domain family member 3	0.042
Ctnna1	catenin (cadherin associated protein), alpha 1	0.041
Ptf1a	pancreas specific transcription factor, 1a	0.041
Pcgf2	polycomb group ring finger 2	0.040	Mouse
Lhx1	LIM homeobox protein 1	0.040
Fgf8	fibroblast growth factor 8	0.040
Pax7	paired box gene 7	0.039
Prrx1	paired related homeobox 1	0.039
Neurod1	neurogenic differentiation 1	0.039
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.037
Efna2	ephrin A2	0.036
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.036
Ptgfr	prostaglandin F receptor	0.036
Rac1	RAS-related C3 botulinum substrate 1	0.035
Prlr	prolactin receptor	0.035
Vhl	von Hippel-Lindau tumor suppressor	0.034
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.034
Pou3f1	POU domain, class 3, transcription factor 1	0.034
Hoxc8	homeobox C8	0.034	Mouse
Hoxd3	homeobox D3	0.034
Tcf7	transcription factor 7, T-cell specific	0.033	Mouse
Pgr	progesterone receptor	0.033
Lrp4	low density lipoprotein receptor-related protein 4	0.032	Mouse
Foxd3	forkhead box D3	0.032
Smad2	MAD homolog 2 (Drosophila)	0.032
Sox7	SRY-box containing gene 7	0.031
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.031
Lrp5	low density lipoprotein receptor-related protein 5	0.031	Mouse
Fzd10	frizzled homolog 10 (Drosophila)	0.031
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.030
Tbx1	T-box 1	0.030
Wnt6	wingless-related MMTV integration site 6	0.030	Mouse
Hoxa3	homeobox A3	0.029
Ntf3	neurotrophin 3	0.028
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.028
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.028	Worm
Ihh	Indian hedgehog	0.028
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.028
Kit	kit oncogene	0.028	Rat
Ccnb2	cyclin B2	0.028
Mmp16	matrix metallopeptidase 16	0.028
Rxra	retinoid X receptor alpha	0.027
Hoxa9	homeobox A9	0.027
Stat5a	signal transducer and activator of transcription 5A	0.027
Kitl	kit ligand	0.027
Hoxb2	homeobox B2	0.027
Fzd7	frizzled homolog 7 (Drosophila)	0.026
Zfp185	zinc finger protein 185	0.026
Sim2	single-minded homolog 2 (Drosophila)	0.026
Kif20a	kinesin family member 20A	0.025
Zfp503	zinc finger protein 503	0.025
Dlg1	discs, large homolog 1 (Drosophila)	0.025
Ppara	peroxisome proliferator activated receptor alpha	0.025
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.025
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.025
Gsk3b	glycogen synthase kinase 3 beta	0.024
Wnt10b	wingless related MMTV integration site 10b	0.024	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.024
Efnb1	ephrin B1	0.024
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.024
Smad3	MAD homolog 3 (Drosophila)	0.023
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.023
Tcf15	transcription factor 15	0.023
Onecut1	one cut domain, family member 1	0.023
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.023
Myod1	myogenic differentiation 1	0.023
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.023
Vax1	ventral anterior homeobox containing gene 1	0.023
Axin2	axin2	0.023
Msi1	Musashi homolog 1(Drosophila)	0.023
Wnt1	wingless-related MMTV integration site 1	0.022	Mouse
Ebf3	early B-cell factor 3	0.022
Wiz	widely-interspaced zinc finger motifs	0.022
Fgf23	fibroblast growth factor 23	0.022
Fgf18	fibroblast growth factor 18	0.022
Tgfa	transforming growth factor alpha	0.022
Tead2	TEA domain family member 2	0.022
Smad6	MAD homolog 6 (Drosophila)	0.022
Rimklb	ribosomal modification protein rimK-like family member B	0.022
Oca2	oculocutaneous albinism II	0.021
Trp73	transformation related protein 73	0.021
Fjx1	four jointed box 1 (Drosophila)	0.021
Zfp703	zinc finger protein 703	0.021
Acan	aggrecan	0.021
Sox9	SRY-box containing gene 9	0.021
Hoxa13	homeobox A13	0.021
Meis2	Meis homeobox 2	0.020
Twist1	twist homolog 1 (Drosophila)	0.020
Igbp1	immunoglobulin (CD79A) binding protein 1	0.020
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.020
Efs	embryonal Fyn-associated substrate	0.020
Svs2	seminal vesicle secretory protein 2	0.020
Plxna3	plexin A3	0.020
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.020
Tbx15	T-box 15	0.020
Bnc1	basonuclin 1	0.020
Sult5a1	sulfotransferase family 5A, member 1	0.020
Mc1r	melanocortin 1 receptor	0.020
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.020
Ptch2	patched homolog 2	0.020
Plekhh2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2	0.019
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.019
Fos	FBJ osteosarcoma oncogene	0.019
Apoe	apolipoprotein E	0.019
Sox5	SRY-box containing gene 5	0.019
Chuk	conserved helix-loop-helix ubiquitous kinase	0.019
Plin1	perilipin 1	0.019
Msx1	homeobox, msh-like 1	0.019
Ret	ret proto-oncogene	0.019
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.019
Pmel	premelanosome protein	0.019
Rb1	retinoblastoma 1	0.019
Wnt11	wingless-related MMTV integration site 11	0.019	Mouse
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.018
Kl	klotho	0.018
Cdk2	cyclin-dependent kinase 2	0.018
Sept1	septin 1	0.018
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.018
Jag1	jagged 1	0.018
Bcl2l10	Bcl2-like 10	0.018
Foxj1	forkhead box J1	0.018
Hes1	hairy and enhancer of split 1 (Drosophila)	0.018
Foxd2	forkhead box D2	0.018
Lhx3	LIM homeobox protein 3	0.018
Pou4f3	POU domain, class 4, transcription factor 3	0.017
Zbtb33	zinc finger and BTB domain containing 33	0.017
Nes	nestin	0.017
Akt1	thymoma viral proto-oncogene 1	0.017
Junb	Jun-B oncogene	0.017
Psen2	presenilin 2	0.017
a	nonagouti	0.017
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.017
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.017
Mdm2	transformed mouse 3T3 cell double minute 2	0.017
Fst	follistatin	0.017
Adra2c	adrenergic receptor, alpha 2c	0.017
Hoxb9	homeobox B9	0.017
T	brachyury	0.017
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.017
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.017
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.017	Fly
Foxi1	forkhead box I1	0.017
Hoxa7	homeobox A7	0.017	Mouse
Cnr1	cannabinoid receptor 1 (brain)	0.017
Hoxb8	homeobox B8	0.017	Mouse
Wnt2b	wingless related MMTV integration site 2b	0.017	Mouse
Vipr2	vasoactive intestinal peptide receptor 2	0.016
Tcf21	transcription factor 21	0.016
Amhr2	anti-Mullerian hormone type 2 receptor	0.016
Gal	galanin	0.016
Foxb1	forkhead box B1	0.016
Foxc1	forkhead box C1	0.016
Bdkrb2	bradykinin receptor, beta 2	0.016
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.016	Worm
Msh2	mutS homolog 2 (E. coli)	0.015
Wls	wntless homolog (Drosophila)	0.015
Lhx5	LIM homeobox protein 5	0.015
Hoxc4	homeobox C4	0.015	Mouse
Pofut1	protein O-fucosyltransferase 1	0.015
Fgf9	fibroblast growth factor 9	0.015	Mouse
Pkdcc	protein kinase domain containing, cytoplasmic	0.015
Adra2a	adrenergic receptor, alpha 2a	0.015
Fgfrl1	fibroblast growth factor receptor-like 1	0.015
Figf	c-fos induced growth factor	0.015
Pick1	protein interacting with C kinase 1	0.015
Tyrp1	tyrosinase-related protein 1	0.015	Mouse
Eda	ectodysplasin-A	0.015
Mmp17	matrix metallopeptidase 17	0.015
Ccnb1	cyclin B1	0.015
Apaf1	apoptotic peptidase activating factor 1	0.015
Fam164c	family with sequence similarity 164, member C	0.014
Bmp5	bone morphogenetic protein 5	0.014
Zfp362	zinc finger protein 362	0.014
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.014
Rnf138	ring finger protein 138	0.014
Car12	carbonic anyhydrase 12	0.014
Bdnf	brain derived neurotrophic factor	0.014
Emid1	EMI domain containing 1	0.014
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.014
Oprd1	opioid receptor, delta 1	0.014
Mmp24	matrix metallopeptidase 24	0.014
Pitx2	paired-like homeodomain transcription factor 2	0.014
Cbfb	core binding factor beta	0.014
Nkx2-1	NK2 homeobox 1	0.014
Efna4	ephrin A4	0.013
Otos	otospiralin	0.013
Jag2	jagged 2	0.013
Fgf3	fibroblast growth factor 3	0.013	Mouse
Zfpm2	zinc finger protein, multitype 2	0.013
Htra3	HtrA serine peptidase 3	0.013
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.013
Wt1	Wilms tumor 1 homolog	0.013
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.013
S1pr3	sphingosine-1-phosphate receptor 3	0.013
Zfp771	zinc finger protein 771	0.013
Gja3	gap junction protein, alpha 3	0.013
Mki67	antigen identified by monoclonal antibody Ki 67	0.013
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.013	Fly
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.013
Zfhx3	zinc finger homeobox 3	0.013
Ckap2	cytoskeleton associated protein 2	0.012
Irs1	insulin receptor substrate 1	0.012
Epha1	Eph receptor A1	0.012
Pdx1	pancreatic and duodenal homeobox 1	0.012
Hdac7	histone deacetylase 7	0.012
Cntn4	contactin 4	0.012
Mrc2	mannose receptor, C type 2	0.012
Clic3	chloride intracellular channel 3	0.012
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.012
Foxd1	forkhead box D1	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.012
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.012
Irs2	insulin receptor substrate 2	0.012
Gnao1	guanine nucleotide binding protein, alpha O	0.012
Col11a1	collagen, type XI, alpha 1	0.012
Efna5	ephrin A5	0.012
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.012
Fzd2	frizzled homolog 2 (Drosophila)	0.012	Mouse
Wnt5b	wingless-related MMTV integration site 5B	0.012	Mouse
Col4a4	collagen, type IV, alpha 4	0.012
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.012
Neurog1	neurogenin 1	0.012
Crlf1	cytokine receptor-like factor 1	0.012
Npr3	natriuretic peptide receptor 3	0.012
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
Lyst	lysosomal trafficking regulator	0.012
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.012
Emx2	empty spiracles homolog 2 (Drosophila)	0.012
Acvr1	activin A receptor, type 1	0.011
Zp2	zona pellucida glycoprotein 2	0.011
Mapk3	mitogen-activated protein kinase 3	0.011
Btg1	B-cell translocation gene 1, anti-proliferative	0.011
Hoxb1	homeobox B1	0.011
Ahr	aryl-hydrocarbon receptor	0.011
Drd2	dopamine receptor D2	0.011
Pou3f4	POU domain, class 3, transcription factor 4	0.011
Kdm1a	lysine (K)-specific demethylase 1A	0.011
Prkd2	protein kinase D2	0.011
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.011
Wnt3	wingless-related MMTV integration site 3	0.011	Mouse
Hif3a	hypoxia inducible factor 3, alpha subunit	0.011
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.011
Socs1	suppressor of cytokine signaling 1	0.011
Irf6	interferon regulatory factor 6	0.011
Shox2	short stature homeobox 2	0.011
Cer1	cerberus 1 homolog (Xenopus laevis)	0.011
Evx2	even skipped homeotic gene 2 homolog	0.011
Sstr4	somatostatin receptor 4	0.011
Pthlh	parathyroid hormone-like peptide	0.011
Foxa2	forkhead box A2	0.011
Slc25a48	solute carrier family 25, member 48	0.011
Greb1	gene regulated by estrogen in breast cancer protein	0.011
Bmp1	bone morphogenetic protein 1	0.011
Mc5r	melanocortin 5 receptor	0.011
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.011
Thpo	thrombopoietin	0.011
Stc1	stanniocalcin 1	0.011
Foxo1	forkhead box O1	0.011
Tcfap2c	transcription factor AP-2, gamma	0.010
Rnd3	Rho family GTPase 3	0.010
Homer3	homer homolog 3 (Drosophila)	0.010
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.010
Tcl1	T-cell lymphoma breakpoint 1	0.010
Nptx1	neuronal pentraxin 1	0.010
Wnt9b	wingless-type MMTV integration site 9B	0.010	Mouse
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.010
Fgfr4	fibroblast growth factor receptor 4	0.010	Mouse
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.010
Sfrp1	secreted frizzled-related protein 1	0.010
Hoxb7	homeobox B7	0.010	Mouse
Porcn	porcupine homolog (Drosophila)	0.010
Fzd6	frizzled homolog 6 (Drosophila)	0.010	Mouse
Ptch1	patched homolog 1	0.010
Snn	stannin	0.010
Runx3	runt related transcription factor 3	0.010
Mitf	microphthalmia-associated transcription factor	0.010
Rrm2	ribonucleotide reductase M2	0.010
Myoz3	myozenin 3	0.010
Cd2ap	CD2-associated protein	0.010
Rem1	rad and gem related GTP binding protein 1	0.010