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Mus musculus

10 genes annotated in mouse

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regulation of cell fate specification

GO:0042659

Any process that mediates the adoption of a specific fate by a cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell fate specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cell fate specification" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	0.999	Worm Fly
Shh	sonic hedgehog	0.989
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.959
Fgfr2	fibroblast growth factor receptor 2	0.949	Mouse
Fgf8	fibroblast growth factor 8	0.939	Zebrafish
Vangl2	vang-like 2 (van gogh, Drosophila)	0.909
Otx2	orthodenticle homolog 2 (Drosophila)	0.862
Pax3	paired box gene 3	0.852
Fgfr1	fibroblast growth factor receptor 1	0.845
Gli3	GLI-Kruppel family member GLI3	0.827
Bmp4	bone morphogenetic protein 4	0.827	Zebrafish
Lef1	lymphoid enhancer binding factor 1	0.804	Worm
Foxc1	forkhead box C1	0.729
Tgfbr2	transforming growth factor, beta receptor II	0.699	Mouse
Rarg	retinoic acid receptor, gamma	0.684
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.645	Fly
Jag1	jagged 1	0.629
Hes1	hairy and enhancer of split 1 (Drosophila)	0.626
Tcfap2a	transcription factor AP-2, alpha	0.592
Alx4	aristaless-like homeobox 4	0.486
Hand2	heart and neural crest derivatives expressed transcript 2	0.435
Notch1	Notch gene homolog 1 (Drosophila)	0.434	Zebrafish Fly
Isl1	ISL1 transcription factor, LIM/homeodomain	0.421
Nf1	neurofibromatosis 1	0.393
Chd7	chromodomain helicase DNA binding protein 7	0.392
Psen1	presenilin 1	0.375
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.364
Sox2	SRY-box containing gene 2	0.356	Mouse
Apc	adenomatosis polyposis coli	0.343
Smad3	MAD homolog 3 (Drosophila)	0.315
Fgf10	fibroblast growth factor 10	0.307
Pbx1	pre B-cell leukemia transcription factor 1	0.302	Fly
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.296
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.286	Fly
Sox9	SRY-box containing gene 9	0.265	Mouse
Foxg1	forkhead box G1	0.264
Hoxd13	homeobox D13	0.264
Hand1	heart and neural crest derivatives expressed transcript 1	0.255
Smo	smoothened homolog (Drosophila)	0.254
Dlx5	distal-less homeobox 5	0.252
Hoxa3	homeobox A3	0.246
Dll1	delta-like 1 (Drosophila)	0.240
Tbx1	T-box 1	0.236
Wnt3a	wingless-related MMTV integration site 3A	0.235	Human
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.234	Worm
Smad6	MAD homolog 6 (Drosophila)	0.223
Gbx2	gastrulation brain homeobox 2	0.223
Prrx1	paired related homeobox 1	0.222
Hoxa1	homeobox A1	0.212
Foxc2	forkhead box C2	0.204
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.195
Acvr1	activin A receptor, type 1	0.195	Mouse
Gli2	GLI-Kruppel family member GLI2	0.194
Tgfb2	transforming growth factor, beta 2	0.189
Smad7	MAD homolog 7 (Drosophila)	0.188
Nos3	nitric oxide synthase 3, endothelial cell	0.185
Eya1	eyes absent 1 homolog (Drosophila)	0.181	Fly
Nkx2-1	NK2 homeobox 1	0.180
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.171
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.171
Sfrp2	secreted frizzled-related protein 2	0.168
Pax2	paired box gene 2	0.166	Fly
Ush1g	Usher syndrome 1G homolog (human)	0.153
Rara	retinoic acid receptor, alpha	0.149
Vegfa	vascular endothelial growth factor A	0.126
Pten	phosphatase and tensin homolog	0.120
Cdh23	cadherin 23 (otocadherin)	0.120
Rarb	retinoic acid receptor, beta	0.105
Gata3	GATA binding protein 3	0.105
Zeb1	zinc finger E-box binding homeobox 1	0.105
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.105	Worm
Vangl1	vang-like 1 (van gogh, Drosophila)	0.102
Pax6	paired box gene 6	0.101	Rat
Notch2	Notch gene homolog 2 (Drosophila)	0.098	Fly
Gata4	GATA binding protein 4	0.097
S1pr3	sphingosine-1-phosphate receptor 3	0.094
Pou4f3	POU domain, class 4, transcription factor 3	0.092
Foxd2	forkhead box D2	0.087
Rb1	retinoblastoma 1	0.086
Esr1	estrogen receptor 1 (alpha)	0.085
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.080
Aplnr	apelin receptor	0.079
Emx1	empty spiracles homolog 1 (Drosophila)	0.078
Tcf15	transcription factor 15	0.078
Ptch1	patched homolog 1	0.075
Pitx2	paired-like homeodomain transcription factor 2	0.073
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.072
Egfr	epidermal growth factor receptor	0.071
Pax9	paired box gene 9	0.070
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.069
Rxra	retinoid X receptor alpha	0.067
Tgfbr1	transforming growth factor, beta receptor I	0.066	Mouse
Nodal	nodal	0.061
Epas1	endothelial PAS domain protein 1	0.058
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.058
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.057
Prrx2	paired related homeobox 2	0.056
Hoxa2	homeobox A2	0.055
Lrp6	low density lipoprotein receptor-related protein 6	0.054
Ebf3	early B-cell factor 3	0.054
Whrn	whirlin	0.054
Pitx1	paired-like homeodomain transcription factor 1	0.052
Mecom	MDS1 and EVI1 complex locus	0.050
Efnb2	ephrin B2	0.047
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.046
Atoh1	atonal homolog 1 (Drosophila)	0.046
Foxf1a	forkhead box F1a	0.045
Tbx2	T-box 2	0.045
Sox11	SRY-box containing gene 11	0.042	Mouse
Smad2	MAD homolog 2 (Drosophila)	0.040
Tgfbr3	transforming growth factor, beta receptor III	0.040
Pdgfb	platelet derived growth factor, B polypeptide	0.040
S1pr2	sphingosine-1-phosphate receptor 2	0.040
Chrd	chordin	0.039
Smad4	MAD homolog 4 (Drosophila)	0.039
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.038
Meox2	mesenchyme homeobox 2	0.038
Dll4	delta-like 4 (Drosophila)	0.038
Sox7	SRY-box containing gene 7	0.038	Mouse
Gata6	GATA binding protein 6	0.038
Bcl2	B-cell leukemia/lymphoma 2	0.037
Wnt6	wingless-related MMTV integration site 6	0.037
Bcl6b	B-cell CLL/lymphoma 6, member B	0.036
Gsc	goosecoid homeobox	0.036
Fzd1	frizzled homolog 1 (Drosophila)	0.036
Notch3	Notch gene homolog 3 (Drosophila)	0.035	Fly
Fgf17	fibroblast growth factor 17	0.035	Zebrafish
Sox13	SRY-box containing gene 13	0.034
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.034
Efnb1	ephrin B1	0.033
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.033	Fly
Kitl	kit ligand	0.033
Meis2	Meis homeobox 2	0.033
Eda	ectodysplasin-A	0.033
Tcf21	transcription factor 21	0.033
Gja1	gap junction protein, alpha 1	0.032
Trp53	transformation related protein 53	0.032
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.031
Braf	Braf transforming gene	0.031
Msx1	homeobox, msh-like 1	0.031	Fly
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.031
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.031
Grxcr1	glutaredoxin, cysteine rich 1	0.030
Ednra	endothelin receptor type A	0.030
She	src homology 2 domain-containing transforming protein E	0.030
Rdh10	retinol dehydrogenase 10 (all-trans)	0.030
Hic1	hypermethylated in cancer 1	0.030
Wnt5a	wingless-related MMTV integration site 5A	0.029
Gli1	GLI-Kruppel family member GLI1	0.029
Gsk3b	glycogen synthase kinase 3 beta	0.028
Fzd7	frizzled homolog 7 (Drosophila)	0.028	Human
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.027
Ids	iduronate 2-sulfatase	0.027
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.027
Tbx15	T-box 15	0.026
Fzd8	frizzled homolog 8 (Drosophila)	0.026
Fgf15	fibroblast growth factor 15	0.026
En1	engrailed 1	0.026
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.025
Hoxa5	homeobox A5	0.025
Smad1	MAD homolog 1 (Drosophila)	0.025
Nog	noggin	0.025	Zebrafish
Lmx1b	LIM homeobox transcription factor 1 beta	0.025
En2	engrailed 2	0.025
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.024
Spry4	sprouty homolog 4 (Drosophila)	0.024
Hoxa10	homeobox A10	0.024
Smad5	MAD homolog 5 (Drosophila)	0.024
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.024
Hoxb3	homeobox B3	0.023
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.023
Cdx2	caudal type homeobox 2	0.023
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.022
Plcg1	phospholipase C, gamma 1	0.021
Efna4	ephrin A4	0.021
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.021
Wnt4	wingless-related MMTV integration site 4	0.021
Hhex	hematopoietically expressed homeobox	0.021
Thrb	thyroid hormone receptor beta	0.021
Mitf	microphthalmia-associated transcription factor	0.021
Gata2	GATA binding protein 2	0.020
Podxl	podocalyxin-like	0.020
Pax8	paired box gene 8	0.020	Fly
Ntn1	netrin 1	0.020
Pou5f1	POU domain, class 5, transcription factor 1	0.020	Human
Myo15	myosin XV	0.020
Bmp5	bone morphogenetic protein 5	0.020
Fgf3	fibroblast growth factor 3	0.019
Tal1	T-cell acute lymphocytic leukemia 1	0.019
Ret	ret proto-oncogene	0.019
Axin2	axin2	0.018	Worm
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.018
Wnt9b	wingless-type MMTV integration site 9B	0.018
Hnf1a	HNF1 homeobox A	0.018	Mouse
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.018
Fli1	Friend leukemia integration 1	0.018
Fuz	fuzzy homolog (Drosophila)	0.018
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.018
Cdh5	cadherin 5	0.018
Hmx3	H6 homeobox 3	0.017	Worm
Ptk7	PTK7 protein tyrosine kinase 7	0.017
Lhx1	LIM homeobox protein 1	0.017
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.017
Nkx3-2	NK3 homeobox 2	0.017
Tcf7	transcription factor 7, T-cell specific	0.017	Worm
Sfrp1	secreted frizzled-related protein 1	0.016	Mouse
Raf1	v-raf-leukemia viral oncogene 1	0.016
Rnf111	ring finger 111	0.016
Tbx3	T-box 3	0.016
Tbx6	T-box 6	0.016
Tlx3	T-cell leukemia, homeobox 3	0.016
Lrp2	low density lipoprotein receptor-related protein 2	0.016
Sox17	SRY-box containing gene 17	0.016
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.016
Emx2	empty spiracles homolog 2 (Drosophila)	0.016
Sox18	SRY-box containing gene 18	0.015	Mouse
Kit	kit oncogene	0.015
Alx3	aristaless-like homeobox 3	0.015
Twist2	twist homolog 2 (Drosophila)	0.015
Hif1a	hypoxia inducible factor 1, alpha subunit	0.015
Padi3	peptidyl arginine deiminase, type III	0.015
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.015
Ldb2	LIM domain binding 2	0.014
Runx2	runt related transcription factor 2	0.014
Creb1	cAMP responsive element binding protein 1	0.014
Phox2b	paired-like homeobox 2b	0.014
Adra2b	adrenergic receptor, alpha 2b	0.014
Lrp5	low density lipoprotein receptor-related protein 5	0.014
Barx1	BarH-like homeobox 1	0.014
Cbfb	core binding factor beta	0.014
Srrm4	serine/arginine repetitive matrix 4	0.014
Pbx2	pre B-cell leukemia transcription factor 2	0.014	Fly
Apaf1	apoptotic peptidase activating factor 1	0.014
Rasip1	Ras interacting protein 1	0.014
Nsd1	nuclear receptor-binding SET-domain protein 1	0.014
Sall3	sal-like 3 (Drosophila)	0.014
Hoxb6	homeobox B6	0.014
Pgr	progesterone receptor	0.014
Otx1	orthodenticle homolog 1 (Drosophila)	0.014
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.013
Prf1	perforin 1 (pore forming protein)	0.013
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.013
Adcy4	adenylate cyclase 4	0.013
Efna2	ephrin A2	0.013
Atoh7	atonal homolog 7 (Drosophila)	0.013
Dhh	desert hedgehog	0.013
Lhb	luteinizing hormone beta	0.013
Hoxb4	homeobox B4	0.013
Adam17	a disintegrin and metallopeptidase domain 17	0.013
Egfl7	EGF-like domain 7	0.012
Gdf11	growth differentiation factor 11	0.012
Alx1	ALX homeobox 1	0.012
Tead3	TEA domain family member 3	0.012
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.012
Fmnl3	formin-like 3	0.012
Npr3	natriuretic peptide receptor 3	0.012
Tmprss3	transmembrane protease, serine 3	0.012
Elf4	E74-like factor 4 (ets domain transcription factor)	0.012
Espn	espin	0.012
Ntf3	neurotrophin 3	0.012
Pou3f1	POU domain, class 3, transcription factor 1	0.012
Ager	advanced glycosylation end product-specific receptor	0.012
Zfp362	zinc finger protein 362	0.012
Pou3f3	POU domain, class 3, transcription factor 3	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
Fgfr3	fibroblast growth factor receptor 3	0.012	Mouse
Htt	huntingtin	0.012
Klf4	Kruppel-like factor 4 (gut)	0.011
Fgf2	fibroblast growth factor 2	0.011	Human
Sox4	SRY-box containing gene 4	0.011	Mouse
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Hr	hairless	0.011
Trp63	transformation related protein 63	0.011
Hdac7	histone deacetylase 7	0.011
Prdm1	PR domain containing 1, with ZNF domain	0.011
Hoxa11	homeobox A11	0.011
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.011
Sox10	SRY-box containing gene 10	0.011	Mouse
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.011
Socs5	suppressor of cytokine signaling 5	0.011
Pkd1	polycystic kidney disease 1 homolog	0.011
Btbd17	BTB (POZ) domain containing 17	0.011
Fzd3	frizzled homolog 3 (Drosophila)	0.011
Skor1	SKI family transcriptional corepressor 1	0.011
Flt4	FMS-like tyrosine kinase 4	0.011
Ccnd1	cyclin D1	0.011
Wiz	widely-interspaced zinc finger motifs	0.011
Kl	klotho	0.010
Fzd6	frizzled homolog 6 (Drosophila)	0.010
Ptgfrn	prostaglandin F2 receptor negative regulator	0.010
Cldn5	claudin 5	0.010
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.010
Hes3	hairy and enhancer of split 3 (Drosophila)	0.010
Wnt1	wingless-related MMTV integration site 1	0.010	Fly
Hoxc4	homeobox C4	0.010
Kdr	kinase insert domain protein receptor	0.010