IMP

Process View

Mus musculus

2 genes annotated in mouse

Multi-species View

regulation of anoikis

GO:2000209

Any process that modulates the frequency, rate or extent of anoikis.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of anoikis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of anoikis" (in gray)

Name	Description	Probability	Func Analog Organism
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.857
Vegfa	vascular endothelial growth factor A	0.788
Hif1a	hypoxia inducible factor 1, alpha subunit	0.781
Egfr	epidermal growth factor receptor	0.742
Pten	phosphatase and tensin homolog	0.675
Psen1	presenilin 1	0.575
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.533
Trp53	transformation related protein 53	0.509
Notch2	Notch gene homolog 2 (Drosophila)	0.463
Pxn	paxillin	0.366
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.343
Rb1	retinoblastoma 1	0.328
Ntf3	neurotrophin 3	0.318
Ret	ret proto-oncogene	0.310
Ptgs2	prostaglandin-endoperoxide synthase 2	0.285
Kit	kit oncogene	0.260
Fgfr1	fibroblast growth factor receptor 1	0.231
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.227
Pparg	peroxisome proliferator activated receptor gamma	0.216
Vhl	von Hippel-Lindau tumor suppressor	0.201
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.200
Ptrf	polymerase I and transcript release factor	0.198
Bcar1	breast cancer anti-estrogen resistance 1	0.173
Ctnnb1	catenin (cadherin associated protein), beta 1	0.172
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	0.169	Human
Bax	BCL2-associated X protein	0.162
Nf1	neurofibromatosis 1	0.154
Lepr	leptin receptor	0.152
Ntf5	neurotrophin 5	0.122
Nrg1	neuregulin 1	0.121
Esr1	estrogen receptor 1 (alpha)	0.117
Zeb1	zinc finger E-box binding homeobox 1	0.116
Braf	Braf transforming gene	0.111
Apc	adenomatosis polyposis coli	0.110
Kitl	kit ligand	0.109
Foxc1	forkhead box C1	0.098
Fgfr2	fibroblast growth factor receptor 2	0.093
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.093	Human
Chd7	chromodomain helicase DNA binding protein 7	0.090
Gal	galanin	0.090
Eng	endoglin	0.085
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.082
Rxra	retinoid X receptor alpha	0.079
Dll1	delta-like 1 (Drosophila)	0.077
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.072
Bdnf	brain derived neurotrophic factor	0.071
Sox9	SRY-box containing gene 9	0.068
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.067
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.064
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.063
Smad4	MAD homolog 4 (Drosophila)	0.058
Meox2	mesenchyme homeobox 2	0.058
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.055	Mouse
Lmna	lamin A	0.053
Ptk2	PTK2 protein tyrosine kinase 2	0.053	Human
Jag1	jagged 1	0.051
Ncoa3	nuclear receptor coactivator 3	0.051
Fgfr3	fibroblast growth factor receptor 3	0.049
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.048
Ptch1	patched homolog 1	0.048
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.048
Tlr4	toll-like receptor 4	0.047
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.047
Gli3	GLI-Kruppel family member GLI3	0.047
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.046
Prkce	protein kinase C, epsilon	0.045
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.044
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.042	Human
Lyst	lysosomal trafficking regulator	0.040
Nos3	nitric oxide synthase 3, endothelial cell	0.039
Wnt5a	wingless-related MMTV integration site 5A	0.039
Efnb2	ephrin B2	0.038
Wt1	Wilms tumor 1 homolog	0.037
Psen2	presenilin 2	0.036
Cd36	CD36 antigen	0.035
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.034
Bmp7	bone morphogenetic protein 7	0.034
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.033
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.033
Csf1	colony stimulating factor 1 (macrophage)	0.033
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.033
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.033
Phox2b	paired-like homeobox 2b	0.031
Dmd	dystrophin, muscular dystrophy	0.030
Bmp2	bone morphogenetic protein 2	0.030
Insr	insulin receptor	0.029
Nos1	nitric oxide synthase 1, neuronal	0.029
Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	0.029
Wasl	Wiskott-Aldrich syndrome-like (human)	0.028
Runx2	runt related transcription factor 2	0.027
Prkci	protein kinase C, iota	0.027
Prrx1	paired related homeobox 1	0.027
Smad3	MAD homolog 3 (Drosophila)	0.027
Foxo1	forkhead box O1	0.026
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.026
Cd44	CD44 antigen	0.026
Gja1	gap junction protein, alpha 1	0.026
Lama5	laminin, alpha 5	0.025
Shh	sonic hedgehog	0.025
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.024
Epha3	Eph receptor A3	0.024
Hand2	heart and neural crest derivatives expressed transcript 2	0.023
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.023
Ikzf3	IKAROS family zinc finger 3	0.023
Lep	leptin	0.022
Ghr	growth hormone receptor	0.022
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.022
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.022
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.022
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.022
Mdm2	transformed mouse 3T3 cell double minute 2	0.021
Foxc2	forkhead box C2	0.021
Bmp5	bone morphogenetic protein 5	0.021
Phox2a	paired-like homeobox 2a	0.021
Tgfb2	transforming growth factor, beta 2	0.021
Col1a1	collagen, type I, alpha 1	0.021
Igf1	insulin-like growth factor 1	0.020
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.020
Itga3	integrin alpha 3	0.020
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.020	Mouse
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.019
Ar	androgen receptor	0.018
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.018
Plcg1	phospholipase C, gamma 1	0.017
Stat3	signal transducer and activator of transcription 3	0.017
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.017
Pbx1	pre B-cell leukemia transcription factor 1	0.017
Lrp6	low density lipoprotein receptor-related protein 6	0.017
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
Apoe	apolipoprotein E	0.017
Bmp4	bone morphogenetic protein 4	0.017
Esr2	estrogen receptor 2 (beta)	0.016
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.016
Adipoq	adiponectin, C1Q and collagen domain containing	0.016
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.016
Fgf2	fibroblast growth factor 2	0.016
Snai1	snail homolog 1 (Drosophila)	0.016
Hoxa1	homeobox A1	0.016
Mid1	midline 1	0.016
Pcdh18	protocadherin 18	0.016
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.015
Igh	immunoglobulin heavy chain complex	0.015
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.015
Mxd1	MAX dimerization protein 1	0.015
Itgb3	integrin beta 3	0.015
Hes1	hairy and enhancer of split 1 (Drosophila)	0.015
L1cam	L1 cell adhesion molecule	0.015
Runx1	runt related transcription factor 1	0.015
Dusp1	dual specificity phosphatase 1	0.015
Vangl2	vang-like 2 (van gogh, Drosophila)	0.015
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.015
Mdm4	transformed mouse 3T3 cell double minute 4	0.014
Bak1	BCL2-antagonist/killer 1	0.014
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.014
Myo6	myosin VI	0.014
Pax2	paired box gene 2	0.014
Kif3a	kinesin family member 3A	0.014
Huwe1	HECT, UBA and WWE domain containing 1	0.014
Ddr2	discoidin domain receptor family, member 2	0.014
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.013
Rarg	retinoic acid receptor, gamma	0.013
Lif	leukemia inhibitory factor	0.013
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.013
Arid5b	AT rich interactive domain 5B (MRF1-like)	0.013
Mocs1	molybdenum cofactor synthesis 1	0.013
Ctnnd1	catenin (cadherin associated protein), delta 1	0.013
Mapk14	mitogen-activated protein kinase 14	0.013
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.013
Ep300	E1A binding protein p300	0.013
Fas	Fas (TNF receptor superfamily member 6)	0.013
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.013
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.013
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.012
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.012
Mapk8	mitogen-activated protein kinase 8	0.012
Hbegf	heparin-binding EGF-like growth factor	0.012
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012
Lrp4	low density lipoprotein receptor-related protein 4	0.012
Isl1	ISL1 transcription factor, LIM/homeodomain	0.012
Pik3r3	phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)	0.012
Ids	iduronate 2-sulfatase	0.012
S1pr3	sphingosine-1-phosphate receptor 3	0.012
Pax3	paired box gene 3	0.012
Foxa2	forkhead box A2	0.012
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.012
Lpin1	lipin 1	0.012
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.012
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.012
Sntb1	syntrophin, basic 1	0.012
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.012
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.012
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.012
Myo1e	myosin IE	0.012
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.011
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.011	Mouse
Cav1	caveolin 1, caveolae protein	0.011
Plau	plasminogen activator, urokinase	0.011
Gdf5	growth differentiation factor 5	0.011
Ehf	ets homologous factor	0.011
Gab2	growth factor receptor bound protein 2-associated protein 2	0.011
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.011
Msx2	homeobox, msh-like 2	0.011
Jag2	jagged 2	0.011
Fosl2	fos-like antigen 2	0.011
Flnb	filamin, beta	0.011
Cd151	CD151 antigen	0.011
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.011
Notch1	Notch gene homolog 1 (Drosophila)	0.011	Human
Col12a1	collagen, type XII, alpha 1	0.011
Nsf	N-ethylmaleimide sensitive fusion protein	0.011
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.010
Ctsk	cathepsin K	0.010
Tead4	TEA domain family member 4	0.010
Sntb2	syntrophin, basic 2	0.010
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.010
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.010
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.010
Numb	numb gene homolog (Drosophila)	0.010
Skor1	SKI family transcriptional corepressor 1	0.010
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.010
Rara	retinoic acid receptor, alpha	0.010
Plin1	perilipin 1	0.010
Midn	midnolin	0.010
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.010
Thbs1	thrombospondin 1	0.010
Has2	hyaluronan synthase 2	0.010
Anapc7	anaphase promoting complex subunit 7	0.010
Lipe	lipase, hormone sensitive	0.010
Chrd	chordin	0.010