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Process View

Mus musculus

23 genes annotated in mouse

centrosome cycle

The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "centrosome cycle"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "centrosome cycle" (in gray)

Name	Description	Probability	Func Analog Organism
Brca1	breast cancer 1	0.951
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.943	Fly
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.901	Fly
Prc1	protein regulator of cytokinesis 1	0.847	Fly
Kif4	kinesin family member 4	0.825
Hspa8	heat shock protein 8	0.786
Rpgrip1l	Rpgrip1-like	0.757
Plk1	polo-like kinase 1 (Drosophila)	0.734	Worm
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.709	Human
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.705	Worm Fly
Anln	anillin, actin binding protein	0.685
Kif11	kinesin family member 11	0.657
Ccnb1	cyclin B1	0.614
Kif20a	kinesin family member 20A	0.614
Kif2c	kinesin family member 2C	0.581	Fly
Mis18bp1	MIS18 binding protein 1	0.552
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.495
Aurkb	aurora kinase B	0.487	Fly
Racgap1	Rac GTPase-activating protein 1	0.485	Fly
Ttk	Ttk protein kinase	0.457
Ccnb2	cyclin B2	0.362
Plk4	polo-like kinase 4 (Drosophila)	0.339
Stil	Scl/Tal1 interrupting locus	0.327
Dtl	denticleless homolog (Drosophila)	0.322
Rad51ap1	RAD51 associated protein 1	0.304
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.297
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.292
Kif23	kinesin family member 23	0.277	Fly
Top2a	topoisomerase (DNA) II alpha	0.272
Rps7	ribosomal protein S7	0.267
Ccna2	cyclin A2	0.257
Rplp0	ribosomal protein, large, P0	0.242
Sass6	spindle assembly 6 homolog (C. elegans)	0.240	Fly
Trp53	transformation related protein 53	0.226
Smc2	structural maintenance of chromosomes 2	0.221
Cdk1	cyclin-dependent kinase 1	0.216
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.216
Spag5	sperm associated antigen 5	0.212
Blm	Bloom syndrome, RecQ helicase-like	0.209
Brca2	breast cancer 2	0.203	Human
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.171
Rpl4	ribosomal protein L4	0.157
Cdca5	cell division cycle associated 5	0.150
Gtse1	G two S phase expressed protein 1	0.147
Rps5	ribosomal protein S5	0.147
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.141
Rpl18	ribosomal protein L18	0.138
Ckap2	cytoskeleton associated protein 2	0.128
Cdc7	cell division cycle 7 (S. cerevisiae)	0.128
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.126
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.125
Skp1a	S-phase kinase-associated protein 1A	0.120
Exo1	exonuclease 1	0.112
Mybl2	myeloblastosis oncogene-like 2	0.109	Fly
Tcp1	t-complex protein 1	0.106
Lin9	lin-9 homolog (C. elegans)	0.106
Ccdc99	coiled-coil domain containing 99	0.103
Mxd3	Max dimerization protein 3	0.102
Trip13	thyroid hormone receptor interactor 13	0.096
Ccnf	cyclin F	0.094	Human
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.093
Ncaph	non-SMC condensin I complex, subunit H	0.092
Tacc3	transforming, acidic coiled-coil containing protein 3	0.090
Ect2	ect2 oncogene	0.089
Usp1	ubiquitin specific peptidase 1	0.088
Orc4	origin recognition complex, subunit 4	0.087
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.087
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.085
Rabep1	rabaptin, RAB GTPase binding effector protein 1	0.084
Iqgap3	IQ motif containing GTPase activating protein 3	0.084
Cacybp	calcyclin binding protein	0.082
Orc1	origin recognition complex, subunit 1	0.080
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.080
Cdca8	cell division cycle associated 8	0.079
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.077
Smc4	structural maintenance of chromosomes 4	0.077
Cenpk	centromere protein K	0.076
Aurka	aurora kinase A	0.073
Cep55	centrosomal protein 55	0.073
Rab5a	RAB5A, member RAS oncogene family	0.072
Arhgap21	Rho GTPase activating protein 21	0.070
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.070
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.067	Fly
Mastl	microtubule associated serine/threonine kinase-like	0.066
Rpl6	ribosomal protein L6	0.066
Diap3	diaphanous homolog 3 (Drosophila)	0.064
E2f8	E2F transcription factor 8	0.064
Naca	nascent polypeptide-associated complex alpha polypeptide	0.063
Rasa1	RAS p21 protein activator 1	0.062
Fam64a	family with sequence similarity 64, member A	0.060
Rps3a	ribosomal protein S3A	0.059
Foxm1	forkhead box M1	0.058
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.057
Incenp	inner centromere protein	0.055
Gsg2	germ cell-specific gene 2	0.054
Cenpn	centromere protein N	0.052
Stag2	stromal antigen 2	0.051
Htt	huntingtin	0.050
Cenpf	centromere protein F	0.050
Invs	inversin	0.049
Rps11	ribosomal protein S11	0.049
Strn3	striatin, calmodulin binding protein 3	0.048
Chek2	CHK2 checkpoint homolog (S. pombe)	0.048
Mns1	meiosis-specific nuclear structural protein 1	0.045
Gm10119	predicted gene 10119	0.044
Fancd2	Fanconi anemia, complementation group D2	0.044
Cdkn3	cyclin-dependent kinase inhibitor 3	0.043
Rpl7a	ribosomal protein L7A	0.042
Cct6a	chaperonin containing Tcp1, subunit 6a (zeta)	0.042
Sgol1	shugoshin-like 1 (S. pombe)	0.041
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.041
Gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1	0.040
Kif22	kinesin family member 22	0.040
Hspa4l	heat shock protein 4 like	0.040
Cdca7l	cell division cycle associated 7 like	0.040
Rps2	ribosomal protein S2	0.040
Sacm1l	SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae)	0.039
Ppia	peptidylprolyl isomerase A	0.038
Birc5	baculoviral IAP repeat-containing 5	0.037
Rps15a	ribosomal protein S15A	0.037
Rps3	ribosomal protein S3	0.037
Ncoa2	nuclear receptor coactivator 2	0.035
Wrn	Werner syndrome homolog (human)	0.035
Wee1	WEE 1 homolog 1 (S. pombe)	0.035	Fly
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.034
Rpl7	ribosomal protein L7	0.033	Fly
Actg1	actin, gamma, cytoplasmic 1	0.033
Trim59	tripartite motif-containing 59	0.032
Rpl21	ribosomal protein L21	0.032
Arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.032
Hsph1	heat shock 105kDa/110kDa protein 1	0.031
Kif5b	kinesin family member 5B	0.031	Fly
LOC100044627	60S ribosomal protein L23-like	0.031
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.031
Ska1	spindle and kinetochore associated complex subunit 1	0.030
Igbp1	immunoglobulin (CD79A) binding protein 1	0.030
Tmpo	thymopoietin	0.029
Rpl10a	ribosomal protein L10A	0.029
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.029	Fly
Nap1l1	nucleosome assembly protein 1-like 1	0.029
Rpl10	ribosomal protein 10	0.027
Nusap1	nucleolar and spindle associated protein 1	0.027
Rpl11	ribosomal protein L11	0.027
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.027
Cenpe	centromere protein E	0.027
E130303B06Rik	RIKEN cDNA E130303B06 gene	0.026
2410089E03Rik	RIKEN cDNA 2410089E03 gene	0.026
Nbn	nibrin	0.026
Smap1	stromal membrane-associated protein 1	0.026
Gmnn	geminin	0.026
Dynll1	dynein light chain LC8-type 1	0.025
Rbl1	retinoblastoma-like 1 (p107)	0.025
Fam54a	family with sequence similarity 54, member A	0.025
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.025
Lmnb1	lamin B1	0.025
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.025
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.025
Dna2	DNA replication helicase 2 homolog (yeast)	0.024
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.024
Mdm2	transformed mouse 3T3 cell double minute 2	0.024
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.024
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.024
Ahi1	Abelson helper integration site 1	0.023
Xpo1	exportin 1, CRM1 homolog (yeast)	0.023
Ckap5	cytoskeleton associated protein 5	0.023
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.023
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.023	Human
Tpr	translocated promoter region	0.022
Cenpa	centromere protein A	0.022
Brsk1	BR serine/threonine kinase 1	0.022
Rps28	ribosomal protein S28	0.021
Apc	adenomatosis polyposis coli	0.021
Top2b	topoisomerase (DNA) II beta	0.021
Rad18	RAD18 homolog (S. cerevisiae)	0.020
Sept7	septin 7	0.020
Eea1	early endosome antigen 1	0.019
Wdr26	WD repeat domain 26	0.019
Bard1	BRCA1 associated RING domain 1	0.019
Tyms	thymidylate synthase	0.019
Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	0.019	Fly
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.019
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.018
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.018
Zfr	zinc finger RNA binding protein	0.018
Pole	polymerase (DNA directed), epsilon	0.018
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.018
Paip2	polyadenylate-binding protein-interacting protein 2	0.018
Brsk2	BR serine/threonine kinase 2	0.018	Mouse
Mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.018
Nae1	NEDD8 activating enzyme E1 subunit 1	0.018
Ift80	intraflagellar transport 80 homolog (Chlamydomonas)	0.017
Mcm10	minichromosome maintenance deficient 10 (S. cerevisiae)	0.017
Cct5	chaperonin containing Tcp1, subunit 5 (epsilon)	0.017
Dbf4	DBF4 homolog (S. cerevisiae)	0.017
Dync1i1	dynein cytoplasmic 1 intermediate chain 1	0.017
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.017
Rpl3	ribosomal protein L3	0.017
Cdca2	cell division cycle associated 2	0.016
Rab10	RAB10, member RAS oncogene family	0.016
Snap25	synaptosomal-associated protein 25	0.016
Atm	ataxia telangiectasia mutated homolog (human)	0.016
Ube2c	ubiquitin-conjugating enzyme E2C	0.016
Stag1	stromal antigen 1	0.016
Rbbp8	retinoblastoma binding protein 8	0.016
Mphosph9	M-phase phosphoprotein 9	0.016
Wbp4	WW domain binding protein 4	0.016
Trip12	thyroid hormone receptor interactor 12	0.016
Xrcc2	X-ray repair complementing defective repair in Chinese hamster cells 2	0.015
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.015
Nup50	nucleoporin 50	0.015
4632434I11Rik	RIKEN cDNA 4632434I11 gene	0.015
Zfand5	zinc finger, AN1-type domain 5	0.015
Golga4	golgi autoantigen, golgin subfamily a, 4	0.015
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.015
Myef2	myelin basic protein expression factor 2, repressor	0.015
Bod1l	biorientation of chromosomes in cell division 1-like	0.015
LOC100503815	60S ribosomal protein L39-like	0.015
Cks2	CDC28 protein kinase regulatory subunit 2	0.015
Gm10335	predicted gene 10335	0.014
Rpl23a	ribosomal protein L23A	0.014	Fly
Piga	phosphatidylinositol glycan anchor biosynthesis, class A	0.014
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.014
Dnm1l	dynamin 1-like	0.014
Dtnb	dystrobrevin, beta	0.014
Rcc1	regulator of chromosome condensation 1	0.014
Cltc	clathrin, heavy polypeptide (Hc)	0.013
Rps19	ribosomal protein S19	0.013
Mms22l	MMS22-like, DNA repair protein	0.013
Rps24	ribosomal protein S24	0.013
Kif2a	kinesin family member 2A	0.013	Fly
Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein	0.013
Skil	SKI-like	0.013
Eif4a2	eukaryotic translation initiation factor 4A2	0.013
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.013
Csnk1a1	casein kinase 1, alpha 1	0.013
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.013
Atp6v1d	ATPase, H+ transporting, lysosomal V1 subunit D	0.013
Rad51c	RAD51 homolog c (S. cerevisiae)	0.013
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.013	Mouse
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.012
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.012
Rplp2	ribosomal protein, large P2	0.012
Haus4	HAUS augmin-like complex, subunit 4	0.012
Ppp4r2	protein phosphatase 4, regulatory subunit 2	0.012
Mbnl3	muscleblind-like 3 (Drosophila)	0.012
Nek8	NIMA (never in mitosis gene a)-related expressed kinase 8	0.012
9430015G10Rik	RIKEN cDNA 9430015G10 gene	0.012
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.012
Ipo5	importin 5	0.012
Zfp62	zinc finger protein 62	0.012
Rad54l	RAD54 like (S. cerevisiae)	0.012
Sertad1	SERTA domain containing 1	0.012
Rplp1	ribosomal protein, large, P1	0.012
Rttn	rotatin	0.012
Rps23	ribosomal protein S23	0.012
Rpl26	ribosomal protein L26	0.012
Pkn2	protein kinase N2	0.011
Rps26	ribosomal protein S26	0.011
Fancg	Fanconi anemia, complementation group G	0.011
Neil3	nei like 3 (E. coli)	0.011
Slbp	stem-loop binding protein	0.011
Clgn	calmegin	0.011
4930534B04Rik	RIKEN cDNA 4930534B04 gene	0.011
Casc5	cancer susceptibility candidate 5	0.011
Lrr1	leucine rich repeat protein 1	0.011
Arpp19	cAMP-regulated phosphoprotein 19	0.011
Psmd11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.011
Mapk6	mitogen-activated protein kinase 6	0.011
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.011
Mdm1	transformed mouse 3T3 cell double minute 1	0.011
Jak2	Janus kinase 2	0.011
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.011	Fly
Vangl2	vang-like 2 (van gogh, Drosophila)	0.011
Zfp617	zinc finger protein 617	0.011
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.011
Mks1	Meckel syndrome, type 1	0.011
Ccne2	cyclin E2	0.011
Cep57l1	centrosomal protein 57-like 1	0.011
Per1	period homolog 1 (Drosophila)	0.010
Psmc3ip	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein	0.010
Slc30a9	solute carrier family 30 (zinc transporter), member 9	0.010
Fbxw7	F-box and WD-40 domain protein 7	0.010
Nckap1	NCK-associated protein 1	0.010
Nlk	nemo like kinase	0.010
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.010
Sumo2	SMT3 suppressor of mif two 3 homolog 2 (yeast)	0.010
Akt3	thymoma viral proto-oncogene 3	0.010
Haus5	HAUS augmin-like complex, subunit 5	0.010
Picalm	phosphatidylinositol binding clathrin assembly protein	0.010
Mybl1	myeloblastosis oncogene-like 1	0.010	Fly