IMP

Process View

Mus musculus

20 genes annotated in mouse

Multi-species View

regulation of myelination

GO:0031641

Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of myelination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of myelination" (in gray)

Name	Description	Probability	Func Analog Organism
Klk1b5	kallikrein 1-related peptidase b5	0.968	Mouse
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.938
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.897
Ctnnb1	catenin (cadherin associated protein), beta 1	0.859
Emx1	empty spiracles homolog 1 (Drosophila)	0.820
Lef1	lymphoid enhancer binding factor 1	0.737	Mouse
Klk1	kallikrein 1	0.707	Mouse
Klk1b21	kallikrein 1-related peptidase b21	0.631	Mouse
Klk1b26	kallikrein 1-related petidase b26	0.583	Mouse
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.509
Klk1b3	kallikrein 1-related peptidase b3	0.490	Mouse
Klk1b11	kallikrein 1-related peptidase b11	0.410	Mouse
Mapkap1	mitogen-activated protein kinase associated protein 1	0.319
Otx2	orthodenticle homolog 2 (Drosophila)	0.310
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.303
Klk1b8	kallikrein 1-related peptidase b8	0.288	Mouse
Shh	sonic hedgehog	0.230
Hes1	hairy and enhancer of split 1 (Drosophila)	0.228	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.204
Klk1b1	kallikrein 1-related peptidase b1	0.191	Mouse
Sox2	SRY-box containing gene 2	0.188
Klk1b9	kallikrein 1-related peptidase b9	0.185	Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.175
Klk1b16	kallikrein 1-related peptidase b16	0.171	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.170
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.156
Klk1b24	kallikrein 1-related peptidase b24	0.142
Otx1	orthodenticle homolog 1 (Drosophila)	0.136
Rb1	retinoblastoma 1	0.132
Klk1b27	kallikrein 1-related peptidase b27	0.128	Mouse
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.124
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.123
Dlg4	discs, large homolog 4 (Drosophila)	0.121	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.118
Braf	Braf transforming gene	0.108
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.100
Fgfr1	fibroblast growth factor receptor 1	0.094
Dlg2	discs, large homolog 2 (Drosophila)	0.093	Mouse
Tcf7	transcription factor 7, T-cell specific	0.085	Mouse
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.084
Cdh2	cadherin 2	0.082	Rat
Prkce	protein kinase C, epsilon	0.078
Foxg1	forkhead box G1	0.076
Nf1	neurofibromatosis 1	0.076
Dlg1	discs, large homolog 1 (Drosophila)	0.075
Dlg3	discs, large homolog 3 (Drosophila)	0.074	Mouse
Pten	phosphatase and tensin homolog	0.073
Raf1	v-raf-leukemia viral oncogene 1	0.072
Egfbp2	epidermal growth factor binding protein type B	0.071
Notch2	Notch gene homolog 2 (Drosophila)	0.071
Ctrb1	chymotrypsinogen B1	0.067
Cd40	CD40 antigen	0.065
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.061
Rarg	retinoic acid receptor, gamma	0.060
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.060
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.060
Esr1	estrogen receptor 1 (alpha)	0.058
Rictor	RPTOR independent companion of MTOR, complex 2	0.057
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.057
Apc	adenomatosis polyposis coli	0.055
Bcl2	B-cell leukemia/lymphoma 2	0.055
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.051
Try5	trypsin 5	0.050
Arc	activity regulated cytoskeletal-associated protein	0.050
Hes5	hairy and enhancer of split 5 (Drosophila)	0.050
Dcc	deleted in colorectal carcinoma	0.050
Ctnnd1	catenin (cadherin associated protein), delta 1	0.047
Trp63	transformation related protein 63	0.047
Dnm1	dynamin 1	0.047
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.046
Trim25	tripartite motif-containing 25	0.045
Homer1	homer homolog 1 (Drosophila)	0.044
Robo1	roundabout homolog 1 (Drosophila)	0.043
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.043
Chd7	chromodomain helicase DNA binding protein 7	0.042
Cela2a	chymotrypsin-like elastase family, member 2A	0.041
Tshr	thyroid stimulating hormone receptor	0.040
Cit	citron	0.040
Psen1	presenilin 1	0.039
Fzd7	frizzled homolog 7 (Drosophila)	0.038
Akt1	thymoma viral proto-oncogene 1	0.038
Trp53	transformation related protein 53	0.038
Gsk3b	glycogen synthase kinase 3 beta	0.038
Numb	numb gene homolog (Drosophila)	0.038
Ctrl	chymotrypsin-like	0.038
Actn2	actinin alpha 2	0.037
Pax2	paired box gene 2	0.036
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.036
Sox11	SRY-box containing gene 11	0.035
Coil	coilin	0.035
Klk1b4	kallikrein 1-related pepidase b4	0.035	Mouse
Pax8	paired box gene 8	0.035
Irs1	insulin receptor substrate 1	0.035
Ppap2b	phosphatidic acid phosphatase type 2B	0.035
Rptor	regulatory associated protein of MTOR, complex 1	0.034
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.034
Hes3	hairy and enhancer of split 3 (Drosophila)	0.034	Mouse
Ina	internexin neuronal intermediate filament protein, alpha	0.033
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.033
Cd28	CD28 antigen	0.032
Nfib	nuclear factor I/B	0.032
Grm1	glutamate receptor, metabotropic 1	0.032
Odz3	odd Oz/ten-m homolog 3 (Drosophila)	0.031	Mouse
Npas3	neuronal PAS domain protein 3	0.031
Sall2	sal-like 2 (Drosophila)	0.031
Plin3	perilipin 3	0.030
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.030
Bdnf	brain derived neurotrophic factor	0.030
Drd2	dopamine receptor D2	0.029
Atr	ataxia telangiectasia and Rad3 related	0.029
Isl1	ISL1 transcription factor, LIM/homeodomain	0.028
Pparg	peroxisome proliferator activated receptor gamma	0.028
Cachd1	cache domain containing 1	0.028
Lyz2	lysozyme 2	0.028
Npc1	Niemann Pick type C1	0.028
Ptprf	protein tyrosine phosphatase, receptor type, F	0.028
Nog	noggin	0.028
Irf9	interferon regulatory factor 9	0.027
Smad4	MAD homolog 4 (Drosophila)	0.027
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.027
Prkcb	protein kinase C, beta	0.026
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.026
Rbl2	retinoblastoma-like 2	0.026
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.025
Akt2	thymoma viral proto-oncogene 2	0.025	Mouse
Mmp15	matrix metallopeptidase 15	0.025
Pgk2	phosphoglycerate kinase 2	0.025
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.025
Hesx1	homeobox gene expressed in ES cells	0.025
Pcdh12	protocadherin 12	0.024
Dsg1a	desmoglein 1 alpha	0.024
Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)	0.024
Drd1a	dopamine receptor D1A	0.024
Src	Rous sarcoma oncogene	0.023
Pvrl3	poliovirus receptor-related 3	0.023
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.023
Egr3	early growth response 3	0.023
Sox4	SRY-box containing gene 4	0.023
Nradd	neurotrophin receptor associated death domain	0.023
Peg3	paternally expressed 3	0.023
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.023
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.023
Rara	retinoic acid receptor, alpha	0.023
Lhx1	LIM homeobox protein 1	0.022
Rac1	RAS-related C3 botulinum substrate 1	0.022
Cela3b	chymotrypsin-like elastase family, member 3B	0.022
Pnliprp2	pancreatic lipase-related protein 2	0.022
Auts2	autism susceptibility candidate 2	0.022
Gzmf	granzyme F	0.021
Lrp6	low density lipoprotein receptor-related protein 6	0.021
Nsf	N-ethylmaleimide sensitive fusion protein	0.020
Sgpl1	sphingosine phosphate lyase 1	0.020
Abi1	abl-interactor 1	0.020
Adcy1	adenylate cyclase 1	0.020
Sycn	syncollin	0.020
Cadm1	cell adhesion molecule 1	0.020
Fgf15	fibroblast growth factor 15	0.020
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.020
Zg16	zymogen granule protein 16	0.020
Mapk14	mitogen-activated protein kinase 14	0.020
Gli3	GLI-Kruppel family member GLI3	0.020
Kalrn	kalirin, RhoGEF kinase	0.020
Traf6	TNF receptor-associated factor 6	0.019
Mks1	Meckel syndrome, type 1	0.019
Ptch1	patched homolog 1	0.019
Fas	Fas (TNF receptor superfamily member 6)	0.019
Ldb3	LIM domain binding 3	0.019
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.019
Cd19	CD19 antigen	0.019
Lrp5	low density lipoprotein receptor-related protein 5	0.018
Ret	ret proto-oncogene	0.018
Nefm	neurofilament, medium polypeptide	0.018
Tex264	testis expressed gene 264	0.018
Cdx2	caudal type homeobox 2	0.018
Axin2	axin2	0.018
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.018
Pofut1	protein O-fucosyltransferase 1	0.018
Rpgrip1l	Rpgrip1-like	0.018
Lta	lymphotoxin A	0.018
Cuzd1	CUB and zona pellucida-like domains 1	0.018
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.018
Pou3f1	POU domain, class 3, transcription factor 1	0.018
Nf2	neurofibromatosis 2	0.018
Fzd4	frizzled homolog 4 (Drosophila)	0.017
Smad6	MAD homolog 6 (Drosophila)	0.017
Ccnd1	cyclin D1	0.017
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.017
Pnliprp1	pancreatic lipase related protein 1	0.017
Stat1	signal transducer and activator of transcription 1	0.017
Ptprd	protein tyrosine phosphatase, receptor type, D	0.017
Dmbt1	deleted in malignant brain tumors 1	0.017
Cdx1	caudal type homeobox 1	0.017
Ifi44	interferon-induced protein 44	0.017
Shank2	SH3/ankyrin domain gene 2	0.017
Utf1	undifferentiated embryonic cell transcription factor 1	0.017
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.017
Bsn	bassoon	0.017
Prox1	prospero-related homeobox 1	0.017
Mapkapk2	MAP kinase-activated protein kinase 2	0.017
Prss3	protease, serine, 3	0.016
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.016
Lhx3	LIM homeobox protein 3	0.016
Wwc1	WW, C2 and coiled-coil domain containing 1	0.016
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.016
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.016
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.016
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.016
Pcdh10	protocadherin 10	0.016
Zfhx3	zinc finger homeobox 3	0.016
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.016
Zfp423	zinc finger protein 423	0.016
Ulk1	Unc-51 like kinase 1 (C. elegans)	0.016
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.016
Syt9	synaptotagmin IX	0.016
Dst	dystonin	0.016
Neurod1	neurogenic differentiation 1	0.016
Drosha	drosha, ribonuclease type III	0.015
Nos1	nitric oxide synthase 1, neuronal	0.015
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.015
Doc2b	double C2, beta	0.015
Foxn1	forkhead box N1	0.015
Ephb4	Eph receptor B4	0.015
Try10	trypsin 10	0.015
Phox2a	paired-like homeobox 2a	0.015
Neurog3	neurogenin 3	0.015
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.015
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.015
Adam10	a disintegrin and metallopeptidase domain 10	0.015
Cd6	CD6 antigen	0.015
Cpa1	carboxypeptidase A1	0.015
Wnt4	wingless-related MMTV integration site 4	0.015
Mtap2	microtubule-associated protein 2	0.015
Irs2	insulin receptor substrate 2	0.015
Tspan12	tetraspanin 12	0.014
Slit2	slit homolog 2 (Drosophila)	0.014
Igf1r	insulin-like growth factor I receptor	0.014
Sort1	sortilin 1	0.014
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.014
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.014
Plekha5	pleckstrin homology domain containing, family A member 5	0.014
Ctnna1	catenin (cadherin associated protein), alpha 1	0.014
Parp12	poly (ADP-ribose) polymerase family, member 12	0.014
Tead2	TEA domain family member 2	0.014
Maf1	MAF1 homolog (S. cerevisiae)	0.014
Krt35	keratin 35	0.014
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.014
Shank3	SH3/ankyrin domain gene 3	0.014
Helt	Hey-like transcription factor (zebrafish)	0.014
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.014
Rarb	retinoic acid receptor, beta	0.014
Ptov1	prostate tumor over expressed gene 1	0.014
Vegfa	vascular endothelial growth factor A	0.014
Efnb3	ephrin B3	0.014
Clps	colipase, pancreatic	0.013
Hsf4	heat shock transcription factor 4	0.013
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.013
Etv2	ets variant gene 2	0.013
Kit	kit oncogene	0.013
Yap1	yes-associated protein 1	0.013
Csnk1g2	casein kinase 1, gamma 2	0.013
Insm1	insulinoma-associated 1	0.013
Blnk	B-cell linker	0.013
Cd40lg	CD40 ligand	0.013
Ctnnd2	catenin (cadherin associated protein), delta 2	0.013
Mobp	myelin-associated oligodendrocytic basic protein	0.013
Smr3a	submaxillary gland androgen regulated protein 3A	0.013
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.013
Epha6	Eph receptor A6	0.012
Myh10	myosin, heavy polypeptide 10, non-muscle	0.012
Krtap8-2	keratin associated protein 8-2	0.012
Avp	arginine vasopressin	0.012
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.012
Mapk9	mitogen-activated protein kinase 9	0.012
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.012
Klk6	kallikrein related-peptidase 6	0.012
Tbx3	T-box 3	0.012
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.012
Safb	scaffold attachment factor B	0.012
Theg	testicular haploid expressed gene	0.012
Krt17	keratin 17	0.012
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.012
Dsg4	desmoglein 4	0.012
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.012
Tnf	tumor necrosis factor	0.012
Kctd20	potassium channel tetramerisation domain containing 20	0.012
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.012
Prkar2b	protein kinase, cAMP dependent regulatory, type II beta	0.012
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.012
Rps6	ribosomal protein S6	0.012
Epha4	Eph receptor A4	0.011
Zfp532	zinc finger protein 532	0.011
Vsnl1	visinin-like 1	0.011
Klc2	kinesin light chain 2	0.011
Tex101	testis expressed gene 101	0.011
Zic2	zinc finger protein of the cerebellum 2	0.011
Zfpm2	zinc finger protein, multitype 2	0.011
Fndc7	fibronectin type III domain containing 7	0.011
Hist1h1t	histone cluster 1, H1t	0.011
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.011
Ggt1	gamma-glutamyltransferase 1	0.011
Cxadr	coxsackie virus and adenovirus receptor	0.011
Klk1b22	kallikrein 1-related peptidase b22	0.011	Mouse
Crb2	crumbs homolog 2 (Drosophila)	0.011
Id3	inhibitor of DNA binding 3	0.011
Usp18	ubiquitin specific peptidase 18	0.011
Bcl6	B-cell leukemia/lymphoma 6	0.011
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.011
Cask	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.011
Apaf1	apoptotic peptidase activating factor 1	0.011
Arhgap32	Rho GTPase activating protein 32	0.011
Aym1	activator of yeast meiotic promoters 1	0.011
Fjx1	four jointed box 1 (Drosophila)	0.011
Rp9	retinitis pigmentosa 9 (human)	0.011
Cttn	cortactin	0.011
C79452	expressed sequence C79452	0.011
Dmrt1	doublesex and mab-3 related transcription factor 1	0.011
Tal2	T-cell acute lymphocytic leukemia 2	0.011
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.011
Hoxd11	homeobox D11	0.011
D10Jhu81e	DNA segment, Chr 10, Johns Hopkins University 81 expressed	0.011
Ssbp3	single-stranded DNA binding protein 3	0.011
Bcl11b	B-cell leukemia/lymphoma 11B	0.011
Ntf3	neurotrophin 3	0.011
Cmklr1	chemokine-like receptor 1	0.011
Foxc1	forkhead box C1	0.011
Duox2	dual oxidase 2	0.011
Pitx2	paired-like homeodomain transcription factor 2	0.011
Srgap1	SLIT-ROBO Rho GTPase activating protein 1	0.011
Fzd2	frizzled homolog 2 (Drosophila)	0.011
Fgfrl1	fibroblast growth factor receptor-like 1	0.011
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.011
Fezf2	Fez family zinc finger 2	0.010
Krtap6-3	keratin associated protein 6-3	0.010
Foxo1	forkhead box O1	0.010
Capn1	calpain 1	0.010
Coq9	coenzyme Q9 homolog (yeast)	0.010
Hoxd13	homeobox D13	0.010
Mog	myelin oligodendrocyte glycoprotein	0.010
Crybb2	crystallin, beta B2	0.010
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.010
Bsdc1	BSD domain containing 1	0.010
Myo10	myosin X	0.010
Hoxb13	homeobox B13	0.010
Smo	smoothened homolog (Drosophila)	0.010
Mybph	myosin binding protein H	0.010
Lyst	lysosomal trafficking regulator	0.010
Dlx6	distal-less homeobox 6	0.010