IMP
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negative regulation of androgen receptor signaling pathway
Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of androgen receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Lepr | leptin receptor | 0.969 | ||
| Lep | leptin | 0.884 | ||
| Ghr | growth hormone receptor | 0.874 | ||
| Fshr | follicle stimulating hormone receptor | 0.590 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.510 | ||
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.461 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.457 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.452 | ||
| Prlr | prolactin receptor | 0.441 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.439 | ||
| Ar | androgen receptor | 0.428 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.414 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.386 | ||
| Egfr | epidermal growth factor receptor | 0.377 | ||
| Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.370 | ||
| Pten | phosphatase and tensin homolog | 0.366 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.352 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.337 | ||
| Nanog | Nanog homeobox | 0.337 | ||
| Trp53 | transformation related protein 53 | 0.330 | ||
| Apc | adenomatosis polyposis coli | 0.314 | ||
| Cav1 | caveolin 1, caveolae protein | 0.306 | ||
| Vdr | vitamin D receptor | 0.286 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.263 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.258 | ||
| Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.256 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.246 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.222 | ||
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.221 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.208 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.207 | ||
| Wt1 | Wilms tumor 1 homolog | 0.171 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.163 | ||
| Drd2 | dopamine receptor D2 | 0.159 | ||
| Irs2 | insulin receptor substrate 2 | 0.157 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.134 | Mouse | |
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.129 | ||
| Hdac2 | histone deacetylase 2 | 0.129 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.095 | ||
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.094 | ||
| Rb1 | retinoblastoma 1 | 0.093 | ||
| Sfrp2 | secreted frizzled-related protein 2 | 0.088 | ||
| Gnrh1 | gonadotropin releasing hormone 1 | 0.087 | ||
| Nostrin | nitric oxide synthase trafficker | 0.079 | ||
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.076 | ||
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.071 | ||
| Shh | sonic hedgehog | 0.070 | ||
| Pgr | progesterone receptor | 0.066 | ||
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.064 | ||
| Kiss1r | KISS1 receptor | 0.064 | ||
| Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.063 | ||
| Npc1 | Niemann Pick type C1 | 0.059 | ||
| Thra | thyroid hormone receptor alpha | 0.059 | ||
| Insr | insulin receptor | 0.059 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.056 | ||
| Ins2 | insulin II | 0.055 | Mouse | |
| Gnrhr | gonadotropin releasing hormone receptor | 0.054 | ||
| Igf1 | insulin-like growth factor 1 | 0.054 | ||
| Mta2 | metastasis-associated gene family, member 2 | 0.052 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.052 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.052 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.051 | ||
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.050 | ||
| Ins1 | insulin I | 0.047 | Mouse | |
| Foxa2 | forkhead box A2 | 0.044 | ||
| Thrb | thyroid hormone receptor beta | 0.043 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.042 | ||
| Ahr | aryl-hydrocarbon receptor | 0.042 | ||
| Clock | circadian locomotor output cycles kaput | 0.042 | ||
| Wwox | WW domain-containing oxidoreductase | 0.040 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.040 | ||
| Kl | klotho | 0.038 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.037 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.037 | ||
| Col14a1 | collagen, type XIV, alpha 1 | 0.037 | ||
| Kit | kit oncogene | 0.037 | ||
| Pax8 | paired box gene 8 | 0.036 | ||
| Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.036 | ||
| Ccnd1 | cyclin D1 | 0.032 | ||
| Cfc1 | cripto, FRL-1, cryptic family 1 | 0.032 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.032 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.031 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.031 | ||
| Trp63 | transformation related protein 63 | 0.031 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.031 | ||
| Tcf21 | transcription factor 21 | 0.029 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.029 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.029 | ||
| Dhx15 | DEAH (Asp-Glu-Ala-His) box polypeptide 15 | 0.029 | ||
| Lefty1 | left right determination factor 1 | 0.028 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.027 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.026 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.026 | ||
| Nodal | nodal | 0.025 | ||
| Il10 | interleukin 10 | 0.025 | ||
| Braf | Braf transforming gene | 0.025 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.025 | ||
| Lyz2 | lysozyme 2 | 0.025 | ||
| Smarcc2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.023 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.023 | ||
| Mrc1 | mannose receptor, C type 1 | 0.023 | ||
| Cdkn1c | cyclin-dependent kinase inhibitor 1C (P57) | 0.022 | ||
| Apoe | apolipoprotein E | 0.022 | ||
| Cry1 | cryptochrome 1 (photolyase-like) | 0.022 | ||
| Smarcd3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 0.022 | ||
| Trim28 | tripartite motif-containing 28 | 0.022 | ||
| Lum | lumican | 0.021 | ||
| Cga | glycoprotein hormones, alpha subunit | 0.021 | ||
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.021 | ||
| Tcf15 | transcription factor 15 | 0.020 | ||
| Cfh | complement component factor h | 0.020 | ||
| Pthlh | parathyroid hormone-like peptide | 0.020 | ||
| Lipa | lysosomal acid lipase A | 0.020 | ||
| Lhx3 | LIM homeobox protein 3 | 0.020 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.020 | ||
| Oxt | oxytocin | 0.020 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.019 | ||
| Lif | leukemia inhibitory factor | 0.019 | ||
| Tcf3 | transcription factor 3 | 0.019 | ||
| Nhlh2 | nescient helix loop helix 2 | 0.019 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.019 | ||
| Sall1 | sal-like 1 (Drosophila) | 0.019 | ||
| Timp1 | tissue inhibitor of metalloproteinase 1 | 0.018 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.018 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.017 | ||
| Adra1b | adrenergic receptor, alpha 1b | 0.017 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.017 | ||
| Meox2 | mesenchyme homeobox 2 | 0.017 | ||
| Ep300 | E1A binding protein p300 | 0.017 | ||
| Lgals12 | lectin, galactose binding, soluble 12 | 0.017 | ||
| Igf1r | insulin-like growth factor I receptor | 0.017 | ||
| Pcdh12 | protocadherin 12 | 0.017 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.016 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.016 | ||
| Nf1 | neurofibromatosis 1 | 0.016 | ||
| Fgf10 | fibroblast growth factor 10 | 0.016 | ||
| Hoxc6 | homeobox C6 | 0.016 | ||
| Foxc1 | forkhead box C1 | 0.016 | ||
| Rxra | retinoid X receptor alpha | 0.016 | ||
| Sp1 | trans-acting transcription factor 1 | 0.015 | ||
| Axin1 | axin 1 | 0.015 | ||
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.015 | ||
| Col15a1 | collagen, type XV, alpha 1 | 0.015 | ||
| Vegfa | vascular endothelial growth factor A | 0.015 | ||
| Per2 | period homolog 2 (Drosophila) | 0.015 | ||
| Ctsk | cathepsin K | 0.015 | ||
| Mfap2 | microfibrillar-associated protein 2 | 0.015 | ||
| Cxcl12 | chemokine (C-X-C motif) ligand 12 | 0.015 | ||
| Epc2 | enhancer of polycomb homolog 2 (Drosophila) | 0.015 | ||
| Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.015 | ||
| Trrap | transformation/transcription domain-associated protein | 0.015 | ||
| Msc | musculin | 0.014 | Mouse | |
| Rnpc3 | RNA-binding region (RNP1, RRM) containing 3 | 0.014 | ||
| Sfrp5 | secreted frizzled-related sequence protein 5 | 0.014 | ||
| Tcl1 | T-cell lymphoma breakpoint 1 | 0.014 | ||
| Foxo3 | forkhead box O3 | 0.014 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.014 | ||
| Nes | nestin | 0.014 | ||
| Obsl1 | obscurin-like 1 | 0.014 | ||
| Tlr2 | toll-like receptor 2 | 0.013 | ||
| E2f1 | E2F transcription factor 1 | 0.013 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.013 | ||
| Upk1a | uroplakin 1A | 0.013 | ||
| Emcn | endomucin | 0.013 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.013 | ||
| Egr2 | early growth response 2 | 0.013 | ||
| Tff2 | trefoil factor 2 (spasmolytic protein 1) | 0.013 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.013 | ||
| Cpa1 | carboxypeptidase A1 | 0.013 | ||
| Gpc3 | glypican 3 | 0.013 | ||
| Osr1 | odd-skipped related 1 (Drosophila) | 0.013 | ||
| Itga1 | integrin alpha 1 | 0.013 | ||
| Srsf4 | serine/arginine-rich splicing factor 4 | 0.013 | ||
| Stat5b | signal transducer and activator of transcription 5B | 0.013 | ||
| Foxg1 | forkhead box G1 | 0.013 | ||
| Tlr4 | toll-like receptor 4 | 0.013 | ||
| Cmtm3 | CKLF-like MARVEL transmembrane domain containing 3 | 0.013 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.012 | ||
| Upk3b | uroplakin 3B | 0.012 | ||
| Axl | AXL receptor tyrosine kinase | 0.012 | ||
| Crhr2 | corticotropin releasing hormone receptor 2 | 0.012 | ||
| L3mbtl2 | l(3)mbt-like 2 (Drosophila) | 0.012 | ||
| Sfrp1 | secreted frizzled-related protein 1 | 0.012 | Human | |
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.012 | Human | |
| Zfp654 | zinc finger protein 654 | 0.012 | ||
| Spp1 | secreted phosphoprotein 1 | 0.012 | ||
| Kdm4c | lysine (K)-specific demethylase 4C | 0.012 | ||
| Mrvi1 | MRV integration site 1 | 0.012 | ||
| Myo7b | myosin VIIB | 0.012 | ||
| Slc30a2 | solute carrier family 30 (zinc transporter), member 2 | 0.012 | ||
| Rarb | retinoic acid receptor, beta | 0.012 | ||
| Islr | immunoglobulin superfamily containing leucine-rich repeat | 0.012 | ||
| Smarce1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 0.012 | ||
| Xpnpep2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 0.012 | ||
| Vgf | VGF nerve growth factor inducible | 0.012 | ||
| Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.012 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.011 | ||
| Gja1 | gap junction protein, alpha 1 | 0.011 | ||
| Ptrf | polymerase I and transcript release factor | 0.011 | ||
| Ogn | osteoglycin | 0.011 | ||
| Ifng | interferon gamma | 0.011 | ||
| Inha | inhibin alpha | 0.011 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.011 | ||
| Brca1 | breast cancer 1 | 0.011 | ||
| Tgm3 | transglutaminase 3, E polypeptide | 0.011 | ||
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.011 | ||
| AI464131 | expressed sequence AI464131 | 0.011 | ||
| Tph2 | tryptophan hydroxylase 2 | 0.011 | ||
| Stk11 | serine/threonine kinase 11 | 0.011 | ||
| Mybpc3 | myosin binding protein C, cardiac | 0.011 | ||
| BC020535 | cDNA sequence BC020535 | 0.011 | ||
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.011 | ||
| Slc6a18 | solute carrier family 6 (neurotransmitter transporter), member 18 | 0.011 | ||
| Arhgdia | Rho GDP dissociation inhibitor (GDI) alpha | 0.011 | ||
| Sgca | sarcoglycan, alpha (dystrophin-associated glycoprotein) | 0.011 | ||
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.011 | ||
| Tbx20 | T-box 20 | 0.011 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.011 | ||
| Prpf8 | pre-mRNA processing factor 8 | 0.010 | ||
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.010 | ||
| Myl3 | myosin, light polypeptide 3 | 0.010 | ||
| Defa-rs2 | defensin, alpha, related sequence 2 | 0.010 | ||
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.010 | ||
| Grn | granulin | 0.010 | ||
| Tbxa2r | thromboxane A2 receptor | 0.010 | ||
| Ly86 | lymphocyte antigen 86 | 0.010 | ||
| Plg | plasminogen | 0.010 | ||
| Pomc | pro-opiomelanocortin-alpha | 0.010 | ||
| Inpp5j | inositol polyphosphate 5-phosphatase J | 0.010 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.010 | ||
| Atr | ataxia telangiectasia and Rad3 related | 0.010 | ||
| Gas1 | growth arrest specific 1 | 0.010 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.010 | ||
| Jph2 | junctophilin 2 | 0.010 |