IMP

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Mus musculus

2 genes annotated in mouse

activation of phospholipase c activity

The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "activation of phospholipase c activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "activation of phospholipase c activity" (in gray)

Name	Description	Probability	Func Analog Organism
Cbl	Casitas B-lineage lymphoma	0.651
Cd247	CD247 antigen	0.366
Cd19	CD19 antigen	0.330
Tcra	T-cell receptor alpha chain	0.228
Lck	lymphocyte protein tyrosine kinase	0.165	Mouse
Was	Wiskott-Aldrich syndrome homolog (human)	0.159
Ikzf1	IKAROS family zinc finger 1	0.156
Blnk	B-cell linker	0.143
Ptprc	protein tyrosine phosphatase, receptor type, C	0.139
Ptk2	PTK2 protein tyrosine kinase 2	0.135
Cd40	CD40 antigen	0.135
Zap70	zeta-chain (TCR) associated protein kinase	0.096
Agtr1a	angiotensin II receptor, type 1a	0.093
Csf1	colony stimulating factor 1 (macrophage)	0.091
Plcg2	phospholipase C, gamma 2	0.080
Fyn	Fyn proto-oncogene	0.077	Mouse
Prkce	protein kinase C, epsilon	0.077
Hcls1	hematopoietic cell specific Lyn substrate 1	0.072
Il2rg	interleukin 2 receptor, gamma chain	0.068
Ptpre	protein tyrosine phosphatase, receptor type, E	0.067
Grb2	growth factor receptor bound protein 2	0.065
Arhgap9	Rho GTPase activating protein 9	0.064
Ncr1	natural cytotoxicity triggering receptor 1	0.061
Sell	selectin, lymphocyte	0.056
Clnk	cytokine-dependent hematopoietic cell linker	0.056
Dok1	docking protein 1	0.055
Cd4	CD4 antigen	0.054
Selp	selectin, platelet	0.054
Gpr97	G protein-coupled receptor 97	0.048
Itgax	integrin alpha X	0.048
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.047
Cd7	CD7 antigen	0.047
Thra	thyroid hormone receptor alpha	0.046
Cybb	cytochrome b-245, beta polypeptide	0.045
Dynlt1b	dynein light chain Tctex-type 1D	0.044
Cd22	CD22 antigen	0.044
Il2rb	interleukin 2 receptor, beta chain	0.043
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.042
Fpr2	formyl peptide receptor 2	0.040
Myo1f	myosin IF	0.039
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.039
Skap2	src family associated phosphoprotein 2	0.039
Vav2	vav 2 oncogene	0.039
Rnase4	ribonuclease, RNase A family 4	0.038
Fgfr4	fibroblast growth factor receptor 4	0.038
Bdkrb1	bradykinin receptor, beta 1	0.036
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.034
Fyb	FYN binding protein	0.033
Itgb2	integrin beta 2	0.033
Vpreb3	pre-B lymphocyte gene 3	0.032
Pou2af1	POU domain, class 2, associating factor 1	0.032
Xcr1	chemokine (C motif) receptor 1	0.032
Ccr6	chemokine (C-C motif) receptor 6	0.032
Lat	linker for activation of T cells	0.032
Gna15	guanine nucleotide binding protein, alpha 15	0.031
Rgs14	regulator of G-protein signaling 14	0.031
Blk	B lymphoid kinase	0.031	Mouse
Fpr1	formyl peptide receptor 1	0.030
Dok2	docking protein 2	0.030
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.030
Fndc7	fibronectin type III domain containing 7	0.029
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.029
Umod	uromodulin	0.029
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.028
Fgf7	fibroblast growth factor 7	0.028
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.028
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.028	Fly
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.027
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.027
Rag2	recombination activating gene 2	0.027
Folr2	folate receptor 2 (fetal)	0.027
Sykb	spleen tyrosine kinase	0.026
AF251705	cDNA sequence AF251705	0.026
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.026
Mesp2	mesoderm posterior 2	0.026
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.025
Mid2	midline 2	0.024
Fcgr1	Fc receptor, IgG, high affinity I	0.024
Adra1b	adrenergic receptor, alpha 1b	0.024
Aoah	acyloxyacyl hydrolase	0.024
Cd3d	CD3 antigen, delta polypeptide	0.023
Il1f5	interleukin 1 family, member 5 (delta)	0.023
Gpr182	G protein-coupled receptor 182	0.023
S1pr4	sphingosine-1-phosphate receptor 4	0.023
Cmklr1	chemokine-like receptor 1	0.023
Duox2	dual oxidase 2	0.023
Ren1	renin 1 structural	0.023
Cnr2	cannabinoid receptor 2 (macrophage)	0.022
Has1	hyaluronan synthase1	0.022
C5ar1	complement component 5a receptor 1	0.022
Ptpra	protein tyrosine phosphatase, receptor type, A	0.022
Cd1d2	CD1d2 antigen	0.022
Olfr15	olfactory receptor 15	0.022
Tex101	testis expressed gene 101	0.021
Cxcr3	chemokine (C-X-C motif) receptor 3	0.021
Pld1	phospholipase D1	0.020
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.020
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.020
Cfh	complement component factor h	0.020
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.020
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.019
Nfam1	Nfat activating molecule with ITAM motif 1	0.019
Cd180	CD180 antigen	0.019
Cttn	cortactin	0.019
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.019
Il1rn	interleukin 1 receptor antagonist	0.019
Icos	inducible T-cell co-stimulator	0.019
Prss30	protease, serine, 30	0.018
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.018
Tll1	tolloid-like	0.018
Epor	erythropoietin receptor	0.018
Hgf	hepatocyte growth factor	0.018
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.018
Bmp5	bone morphogenetic protein 5	0.018
Il1a	interleukin 1 alpha	0.018
Ly9	lymphocyte antigen 9	0.017
Ciita	class II transactivator	0.017
Amac1	acyl-malonyl condensing enzyme 1	0.017
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.017
Prdm1	PR domain containing 1, with ZNF domain	0.017
Pcdh12	protocadherin 12	0.017
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.017
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.017
Gzmb	granzyme B	0.016
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.016
Fabp1	fatty acid binding protein 1, liver	0.016
Slc12a1	solute carrier family 12, member 1	0.016
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.016
Cd300ld	CD300 molecule-like family member d	0.016
Stat6	signal transducer and activator of transcription 6	0.016
Ednrb	endothelin receptor type B	0.016
Ldb2	LIM domain binding 2	0.016
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.016
Inpp5d	inositol polyphosphate-5-phosphatase D	0.016
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.016
Vipr2	vasoactive intestinal peptide receptor 2	0.016
Snai1	snail homolog 1 (Drosophila)	0.016
Hck	hemopoietic cell kinase	0.016	Mouse
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.016
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.016
Hhex	hematopoietically expressed homeobox	0.015
H2-Ob	histocompatibility 2, O region beta locus	0.015
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.015
Gm14548	predicted gene 14548	0.015
Pla2g1b	phospholipase A2, group IB, pancreas	0.015
Cd72	CD72 antigen	0.015
Cdcp1	CUB domain containing protein 1	0.015
Igh	immunoglobulin heavy chain complex	0.015
Sit1	suppression inducing transmembrane adaptor 1	0.015
Mecom	MDS1 and EVI1 complex locus	0.015
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.015
Mcoln2	mucolipin 2	0.015
Hcst	hematopoietic cell signal transducer	0.015
C78444	expressed sequence C78444	0.015
Car5a	carbonic anhydrase 5a, mitochondrial	0.015
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.015
Slc25a45	solute carrier family 25, member 45	0.015
Ctsw	cathepsin W	0.014
Prl6a1	prolactin family 6, subfamily a, member 1	0.014
Cd6	CD6 antigen	0.014
Lpar4	lysophosphatidic acid receptor 4	0.014
Krt2	keratin 2	0.014
Rasal3	RAS protein activator like 3	0.014
Prl8a6	prolactin family 8, subfamily a, member 6	0.014
Cd300a	CD300A antigen	0.014
BC013712	cDNA sequence BC013712	0.014
Cd8b1	CD8 antigen, beta chain 1	0.014
Prl7d1	prolactin family 7, subfamily d, member 1	0.014
Lect2	leukocyte cell-derived chemotaxin 2	0.014
Prss29	protease, serine, 29	0.014
Cela2a	chymotrypsin-like elastase family, member 2A	0.014
Ptprg	protein tyrosine phosphatase, receptor type, G	0.014
Lifr	leukemia inhibitory factor receptor	0.014
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.014
Hrh4	histamine receptor H4	0.014
Defa-rs12	defensin, alpha, related sequence 12	0.014
Btc	betacellulin, epidermal growth factor family member	0.014
Tspan12	tetraspanin 12	0.014
Fcrla	Fc receptor-like A	0.014
Fasl	Fas ligand (TNF superfamily, member 6)	0.014
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.014
Pilra	paired immunoglobin-like type 2 receptor alpha	0.014
Klk1b8	kallikrein 1-related peptidase b8	0.014
Pou6f1	POU domain, class 6, transcription factor 1	0.014
Cd5l	CD5 antigen-like	0.014
Aard	alanine and arginine rich domain containing protein	0.014
Reg3b	regenerating islet-derived 3 beta	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.013
Stac2	SH3 and cysteine rich domain 2	0.013
Gpr18	G protein-coupled receptor 18	0.013
Cd37	CD37 antigen	0.013
Arhgap29	Rho GTPase activating protein 29	0.013
Gdf9	growth differentiation factor 9	0.013
Foxn1	forkhead box N1	0.013
Reg1	regenerating islet-derived 1	0.013
Cd38	CD38 antigen	0.013
Myo1b	myosin IB	0.013
Pvrl3	poliovirus receptor-related 3	0.013
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.013
Grem2	gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)	0.013
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.013
Cd3e	CD3 antigen, epsilon polypeptide	0.013
Drd4	dopamine receptor D4	0.013
Bcar1	breast cancer anti-estrogen resistance 1	0.013
Sh3d19	SH3 domain protein D19	0.013
Ccr7	chemokine (C-C motif) receptor 7	0.013
Klf12	Kruppel-like factor 12	0.013
Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	0.013
Mlf2	myeloid leukemia factor 2	0.013
Dsg2	desmoglein 2	0.013
Il18rap	interleukin 18 receptor accessory protein	0.013
Clec4f	C-type lectin domain family 4, member f	0.013
Cd96	CD96 antigen	0.013
Has2	hyaluronan synthase 2	0.013
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.013
Psg19	pregnancy specific glycoprotein 19	0.013
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.012
Ltc4s	leukotriene C4 synthase	0.012
BC020535	cDNA sequence BC020535	0.012
Jak3	Janus kinase 3	0.012
Zp1	zona pellucida glycoprotein 1	0.012
Oprl1	opioid receptor-like 1	0.012
Pgr	progesterone receptor	0.012
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.012
Pdyn	prodynorphin	0.012
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.012
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.012
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.012
Acpp	acid phosphatase, prostate	0.012
Gpr35	G protein-coupled receptor 35	0.012
Prss32	protease, serine, 32	0.012
Sh2d2a	SH2 domain protein 2A	0.012
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.012
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.012
Bcl6	B-cell leukemia/lymphoma 6	0.012
Fam65b	family with sequence similarity 65, member B	0.012
Upp2	uridine phosphorylase 2	0.012
Pcdhb8	protocadherin beta 8	0.012
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.012
Chia	chitinase, acidic	0.012
Sfpi1	SFFV proviral integration 1	0.012
Cetn1	centrin 1	0.012
Cd244	CD244 natural killer cell receptor 2B4	0.012
Lcp2	lymphocyte cytosolic protein 2	0.012
Il9	interleukin 9	0.012
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.012
Ngp	neutrophilic granule protein	0.012
Mgl2	macrophage galactose N-acetyl-galactosamine specific lectin 2	0.012
Ccl1	chemokine (C-C motif) ligand 1	0.012
Fas	Fas (TNF receptor superfamily member 6)	0.012
Cd79b	CD79B antigen	0.012
Slpi	secretory leukocyte peptidase inhibitor	0.012
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.012
Frk	fyn-related kinase	0.012	Mouse
Fpr-rs3	formyl peptide receptor, related sequence 3	0.012
Ahsg	alpha-2-HS-glycoprotein	0.011
Cav1	caveolin 1, caveolae protein	0.011
Sec31a	Sec31 homolog A (S. cerevisiae)	0.011
Cpd	carboxypeptidase D	0.011
Dnase1l3	deoxyribonuclease 1-like 3	0.011
Clec4d	C-type lectin domain family 4, member d	0.011
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.011
Cts7	cathepsin 7	0.011
Ccl22	chemokine (C-C motif) ligand 22	0.011
Brs3	bombesin-like receptor 3	0.011
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.011
Rfpl4	ret finger protein-like 4	0.011
Gpld1	glycosylphosphatidylinositol specific phospholipase D1	0.011
Psp	parotid secretory protein	0.011
Pdgfd	platelet-derived growth factor, D polypeptide	0.011
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	0.011
Ghrl	ghrelin	0.011
Tcstv1	2-cell-stage, variable group, member 1	0.011
Vnn1	vanin 1	0.011
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.011
Apoe	apolipoprotein E	0.011
Tfpi2	tissue factor pathway inhibitor 2	0.011
Cr2	complement receptor 2	0.011
Ccr3	chemokine (C-C motif) receptor 3	0.011
Lepr	leptin receptor	0.011
Calcrl	calcitonin receptor-like	0.011
Cd300lf	CD300 antigen like family member F	0.011
Ear5	eosinophil-associated, ribonuclease A family, member 5	0.011
Mmp12	matrix metallopeptidase 12	0.011
Fcrl1	Fc receptor-like 1	0.011
Rac2	RAS-related C3 botulinum substrate 2	0.011
Inhbc	inhibin beta-C	0.011
Col12a1	collagen, type XII, alpha 1	0.011
Hp	haptoglobin	0.011
Ifitm6	interferon induced transmembrane protein 6	0.011
Ccr9	chemokine (C-C motif) receptor 9	0.011
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
Itgal	integrin alpha L	0.011
Gabrr2	gamma-aminobutyric acid (GABA) C receptor, subunit rho 2	0.011
Treml4	triggering receptor expressed on myeloid cells-like 4	0.011
Dock5	dedicator of cytokinesis 5	0.011
Cd3g	CD3 antigen, gamma polypeptide	0.011
Cd209e	CD209e antigen	0.011
Phldb2	pleckstrin homology-like domain, family B, member 2	0.011
Fam171a1	family with sequence similarity 171, member A1	0.011
Gja10	gap junction protein, alpha 10	0.011
Hsd17b13	hydroxysteroid (17-beta) dehydrogenase 13	0.011
Ceacam12	carcinoembryonic antigen-related cell adhesion molecule 12	0.011
She	src homology 2 domain-containing transforming protein E	0.011
Pzp	pregnancy zone protein	0.011
Sftpb	surfactant associated protein B	0.011
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.011
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.011
Klra20	killer cell lectin-like receptor subfamily A, member 20	0.010
Ptprj	protein tyrosine phosphatase, receptor type, J	0.010
Avpr1a	arginine vasopressin receptor 1A	0.010
Ebi3	Epstein-Barr virus induced gene 3	0.010
Aqp2	aquaporin 2	0.010
Ncf1	neutrophil cytosolic factor 1	0.010
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.010
Ptgfr	prostaglandin F receptor	0.010
Clps	colipase, pancreatic	0.010
Marco	macrophage receptor with collagenous structure	0.010
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.010
Tpo	thyroid peroxidase	0.010
Gkn1	gastrokine 1	0.010
Xcl1	chemokine (C motif) ligand 1	0.010
Cubn	cubilin (intrinsic factor-cobalamin receptor)	0.010
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.010
Ctsr	cathepsin R	0.010
Fermt3	fermitin family homolog 3 (Drosophila)	0.010
Znrf4	zinc and ring finger 4	0.010
Angpt1	angiopoietin 1	0.010
Sash3	SAM and SH3 domain containing 3	0.010
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.010
Ptk6	PTK6 protein tyrosine kinase 6	0.010	Mouse
Igk	immunoglobulin kappa chain complex	0.010
Slfn1	schlafen 1	0.010
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.010
Peg10	paternally expressed 10	0.010
F5	coagulation factor V	0.010
Nppc	natriuretic peptide type C	0.010
Ghrh	growth hormone releasing hormone	0.010
Plg	plasminogen	0.010
Tmem115	transmembrane protein 115	0.010
Gm2717	predicted gene 2717	0.010
Pla2r1	phospholipase A2 receptor 1	0.010