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Danio rerio

31 genes annotated in zebrafish

axis elongation

The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "axis elongation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "axis elongation" (in gray)

Name	Description	Probability	Func Analog Organism
bmp2b	bone morphogenetic protein 2b	0.705
hnf1ba	HNF1 homeobox Ba	0.687	Mouse
bmp4	bone morphogenetic protein 4	0.625	Human Mouse
bon	bonnie and clyde	0.602
wnt5b	wingless-type MMTV integration site family, member 5b	0.568
wnt11	wingless-type MMTV integration site family, member 11	0.552
tbx1	T-box 1	0.502	Zebrafish
osr2	odd-skipped related 2 (Drosophila)	0.453
pax2a	paired box gene 2a	0.385
mib	mind bomb	0.355
cdh2	cadherin 2, neuronal	0.310
bmp2a	bone morphogenetic protein 2a	0.290
fn1	fibronectin 1	0.282
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.253
flh	floating head	0.239
oep	one-eyed pinhead	0.224
hoxd4a	homeo box D4a	0.200
wnt3a	wingless-type MMTV integration site family, member 3A	0.188	Zebrafish Mouse
chd	chordin	0.178
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.161
smad9	MAD homolog 9 (Drosophila)	0.160
brd4	bromodomain containing 4	0.156
tbx5a	T-box 5a	0.147	Zebrafish
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.145
notch1a	notch homolog 1a	0.145
osr1	odd-skipped related 1 (Drosophila)	0.136
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.133
eya1	eyes absent homolog 1	0.131
fgf3	fibroblast growth factor 3	0.129
shhb	sonic hedgehog b	0.128	Mouse
raraa	retinoic acid receptor, alpha a	0.124
tbx16	T-box gene 16	0.113	Zebrafish
wnt9b	wingless-type MMTV integration site family, member 9B	0.102	Zebrafish
eomesa	eomesodermin homolog a	0.095	Zebrafish
smad5	MAD homolog 5 (Drosophila)	0.092
shha	sonic hedgehog a	0.086	Mouse
eng1a	engrailed 1a	0.085
wnt4a	wingless-type MMTV integration site family, member 4a	0.083	Zebrafish
wnt8a	wingless-type MMTV integration site family, member 8a	0.082	Zebrafish
vent	ventral expressed homeobox	0.080
bambib	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b	0.075
pou5f1	POU domain, class 5, transcription factor 1	0.070
jag2	jagged 2	0.068
ptch2	patched 2	0.068
wnt8b	wingless-type MMTV integration site family, member 8b	0.064	Zebrafish
foxp1b	forkhead box P1b	0.064
rest	RE1-silencing transcription factor	0.064
nkx3.2	NK3 homeobox 2	0.062
eve1	even-skipped-like1	0.061
ftr82	finTRIM family, member 82	0.060
pkd2	polycystic kidney disease 2	0.058
col2a1a	collagen type II, alpha-1a	0.057
eaf2	ELL associated factor 2	0.055
dlx2a	distal-less homeobox gene 2a	0.054
pcdh8	protocadherin 8	0.054
cfl2l	cofilin 2, like	0.053
fgf8a	fibroblast growth factor 8 a	0.052
nkd2	naked cuticle homolog 2 and naked 2a	0.052
cdx1b	caudal type homeobox 1 b	0.051
smo	smoothened homolog (Drosophila)	0.050
her5	hairy-related 5	0.050
dharma	dharma	0.049
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.049
map2k4a	mitogen-activated protein kinase kinase 4a	0.049
hgfa	hepatocyte growth factor a	0.048
vangl2	vang-like 2 (van gogh, Drosophila)	0.047
msxc	muscle segment homeobox C	0.046
hoxa9b	homeo box A9b	0.044
zgc:175195	zgc:175195	0.044
gli1	GLI-Kruppel family member 1	0.044
acvr1l	activin A receptor, type I like	0.044
zgc:171495	zgc:171495	0.043
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.042
cdh1	cadherin 1, epithelial	0.042	Zebrafish
gpc4	glypican 4	0.041
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.040
col11a2	collagen type XI alpha-2	0.040
twist3	twist3	0.039
rarab	retinoic acid receptor, alpha b	0.039
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.038
sema3d	semaphorin 3d	0.037
fzd10	frizzled homolog 10	0.037
foxi1	forkhead box I1	0.036
lnx2b	ligand of numb-protein X 2b	0.036
tgfb3	transforming growth factor, beta 3	0.035
tbx18	T-box 18	0.034	Zebrafish
fzd8b	frizzled homolog 8b	0.034
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.033
six2a	sine oculis-related homeobox 2a	0.033
si:dkey-273o13.1	si:dkey-273o13.1	0.033
klf2b	Kruppel-like factor 2b	0.033
pdzk1	PDZ domain containing 1	0.033
vsx1	visual system homeobox 1 homolog, chx10-like	0.031
prkar1aa	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a	0.031
sept6	septin 6	0.030
ndr2	nodal-related 2	0.030
lrp2	low density lipoprotein-related protein 2	0.029
col11a1a	collagen, type XI, alpha 1a	0.029
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.028
wnt9a	wingless-type MMTV integration site family, member 9A	0.028	Zebrafish
sp5l	Sp5 transcription factor-like	0.028
boc	brother of CDO	0.028
vmhc	ventricular myosin heavy chain	0.028
aplnrb	apelin receptor b	0.028
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.028	Zebrafish
dld	deltaD	0.028
ephb4b	eph receptor B4b	0.028
ptrfb	polymerase I and transcript release factor b	0.027
efemp2	EGF-containing fibulin-like extracellular matrix protein 2	0.027
sox17	SRY-box containing gene 17	0.027
dzip1	DAZ interacting protein 1	0.027
ndr1	nodal-related 1	0.027
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.027
celf1	cugbp, Elav-like family member 1	0.027
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.027	Mouse
tbx24	T-box 24	0.027	Zebrafish
foxd3	forkhead box D3	0.027
hoxa11b	homeo box A11b	0.026
zeb2a	zinc finger E-box binding homeobox 2a	0.026
cobl	cordon-bleu homolog (mouse)	0.025
emx1	empty spiracles homeobox 1	0.025
epcam	epithelial cell adhesion molecule	0.025
wif1	wnt inhibitory factor 1	0.025
lox	lysyl oxidase	0.025
gsc	goosecoid	0.025
cdx4	caudal type homeo box transcription factor 4	0.025
lft2	lefty2	0.024
col7a1l	collagen type VII alpha 1-like	0.024
hoxd12a	homeo box D12a	0.024
tpm4	tropomyosin 4	0.024
myod1	myogenic differentiation 1	0.024
waca	WW domain containing adaptor with coiled-coil a	0.024
ldb2b	LIM-domain binding factor 2b	0.024
sfrp1b	secreted frizzled-related protein 1b	0.024	Mouse
acana	aggrecan a	0.023
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.023
hoxa13b	homeo box A13b	0.023
fbln1	fibulin 1	0.023
gpr98	G protein-coupled receptor 98	0.023
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.023
pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.023
pomca	proopiomelanocortin a	0.023
col5a2l	collagen, type V, alpha 2-like	0.022
htra1a	HtrA serine peptidase 1a	0.022
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.021
zgc:112211	zgc:112211	0.021
fzd7b	frizzled homolog 7b	0.021
wt1a	wilms tumor 1a	0.021
si:dkey-19p15.7	si:dkey-19p15.7	0.021
hhip	hedgehog interacting protein	0.021
ssrp1b	structure specific recognition protein 1b	0.021
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.021
ntn2	netrin 2	0.020
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.020
xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	0.020
hoxc8a	homeo box C8a	0.020
fgf1	fibroblast growth factor 1	0.020	Human
tbx2a	T-box gene 2a	0.020	Zebrafish
gbx2	gastrulation brain homeo box 2	0.020
wnt10a	wingless-type MMTV integration site family, member 10a	0.020	Zebrafish
ift80	intraflagellar transport 80 homolog (Chlamydomonas)	0.020
igfbp3	insulin-like growth factor binding protein 3	0.020
spry4	sprouty (Drosophila) homolog 4	0.020
ntla	no tail a	0.020
spry1	sprouty homolog 1 (Drosophila)	0.019
meis3	myeloid ecotropic viral integration site 3	0.019
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.019
krt18	keratin 18	0.019
notum3	notum 3	0.019
zgc:113210	zgc:113210	0.019
metrn	meteorin, glial cell differentiation regulator	0.019
ggnbp2	gametogenetin binding protein 2	0.019
wnt2	wingless-type MMTV integration site family member 2	0.018	Zebrafish
rnd1l	Rho family GTPase 1 like	0.018
slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.018
mecom	MDS1 and EVI1 complex locus	0.018
irx2a	iroquois homeobox protein 2, a	0.018
spon2b	spondin 2b, extracellular matrix protein	0.018
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.018
wu:fb54a03	wu:fb54a03	0.018
ecrg4a	esophageal cancer related gene 4a	0.018
atoh1a	atonal homolog 1a	0.018
LOC572344	hypothetical protein LOC572344	0.018
ccnt2a	cyclin T2a	0.018
zgc:66097	zgc:66097	0.018
tll1	tolloid-like 1	0.018
esr2b	estrogen receptor 2b	0.018
efnb1	ephrin B1	0.018
irx1b	iroquois homeobox protein 1, b	0.018
grnb	granulin b	0.017
rgs4	regulator of G-protein signalling 4	0.017
lft1	lefty1	0.017
neo1	neogenin 1	0.017
syne2a	spectrin repeat containing, nuclear envelope 2a	0.017
akt1s1	AKT1 substrate 1 (proline-rich)	0.017
esr2a	estrogen receptor 2a	0.017
jazf1b	JAZF zinc finger 1b	0.017
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.017
map2k4b	mitogen-activated protein kinase kinase 4b	0.016
gli3	GLI-Kruppel family member GLI3	0.016
zgc:111821	zgc:111821	0.016
plk3	polo-like kinase 3 (Drosophila)	0.016
mapk6	mitogen-activated protein kinase 6	0.016
map2k7	mitogen-activated protein kinase kinase 7	0.016
si:ch211-173o4.2	si:ch211-173o4.2	0.016
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.016
fzd7a	frizzled homolog 7a	0.016
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.016
pcdh18b	protocadherin 18b	0.016
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.016
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.016
LOC566708	FL cytokine receptor-like	0.016
gata6	GATA-binding protein 6	0.016
wnt16	wingless-type MMTV integration site family, member 16	0.016
evx2	even-skipped homeobox 2	0.016
cdh6	cadherin 6	0.016
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.016
LOC797832	similar to signal peptide, CUB domain, EGF-like 1	0.015
traf4a	tnf receptor-associated factor 4a	0.015
foxi3b	forkhead box I3b	0.015
ret1	receptor tyrosine kinase	0.015
enpp6	ectonucleotide pyrophosphatase/phosphodiesterase 6	0.015
ptmab	prothymosin, alpha b	0.015
fgf10a	fibroblast growth factor 10a	0.015	Mouse
alcamb	activated leukocyte cell adhesion molecule b	0.015
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.015
ankrd6	ankyrin repeat domain 6	0.015
irx4b	iroquois homeobox protein 4b	0.015
fzd5	frizzled homolog 5	0.015
wnt11r	wingless-type MMTV integration site family, member 11, related	0.015	Zebrafish
zgc:110298	zgc:110298	0.015
spint1a	serine peptidase inhibitor, Kunitz type 1 a	0.015
hoxa11a	homeo box A11a	0.015
dlb	deltaB	0.015
tlx2	T-cell leukemia, homeobox 2	0.015
gata4	GATA-binding protein 4	0.015
cdh11	cadherin 11, osteoblast	0.015
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.014
gnb1b	guanine nucleotide binding protein (G protein), beta polypeptide 1b	0.014
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.014
lzts2a	leucine zipper, putative tumor suppressor 2a	0.014
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.014
dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.014
hoxb1b	homeo box B1b	0.014
ift57	intraflagellar transport protein 57	0.014
cldnc	claudin c	0.014
znf395a	zinc finger protein 395a	0.014
tlx3b	T-cell leukemia, homeobox 3b	0.014
hand2	heart and neural crest derivatives expressed transcript 2	0.014
tbx5b	T-box 5b	0.014
slc4a4a	solute carrier family 4, member 4a	0.014
ift172	intraflagellar transport 172	0.014
hoxa9a	homeo box A9a	0.014
myst2	MYST histone acetyltransferase 2	0.014
twist2	twist2	0.014
angpt1	angiopoietin 1	0.014
ampd3	adenosine monophosphate deaminase 3	0.013
fibpl	fibroblast growth factor (acidic) intracellular binding protein, like	0.013
dkk1b	dickkopf 1b	0.013
hmx3	homeo box (H6 family) 3	0.013
lmo4a	LIM domain only 4a	0.013
prl	prolactin	0.013
htr1ab	5-hydroxytryptamine (serotonin) receptor 1A b	0.013
fezf2	FEZ family zinc finger 2	0.013
otx2	orthodenticle homolog 2	0.013
irgq1	immunity-related GTPase family, q1	0.013
grhl2a	grainyhead-like 2a (Drosophila)	0.013
sox10	SRY-box containing gene 10	0.013
hoxd3a	homeo box D3a	0.013
cc2d2a	coiled-coil and C2 domain containing 2A	0.013
pmp22a	peripheral myelin protein 22a	0.013
ap3s2	adaptor-related protein complex 3, sigma 2 subunit	0.013
odc1	ornithine decarboxylase 1	0.013
wnt1	wingless-type MMTV integration site family, member 1	0.013	Zebrafish
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.013
ypel3	yippee-like 3	0.013
gbas	glioblastoma amplified sequence	0.013
inppl1a	inositol polyphosphate phosphatase-like 1a	0.013
runx2b	runt-related transcription factor 2b	0.013
uap1	UDP-N-acteylglucosamine pyrophosphorylase 1	0.013
hoxd10a	homeo box D10a	0.013
jam2a	junctional adhesion molecule 2a	0.013
tbx6	T-box gene 6	0.012	Zebrafish
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.012
sox32	SRY-box containing gene 32	0.012
vasp	vasodilator-stimulated phosphoprotein	0.012
loxl2b	lysyl oxidase-like 2b	0.012
krt4	keratin 4	0.012
ppp4cb	protein phosphatase 4 (formerly X), catalytic subunit b	0.012
cubn	cubilin (intrinsic factor-cobalamin receptor)	0.012
tshb	thyroid stimulating hormone, beta subunit	0.012
si:ch1073-351m12.1	si:ch1073-351m12.1	0.012
gmcl1	germ cell-less homolog 1 (Drosophila)	0.012
foxg1a	forkhead box G1a	0.012
trim3a	tripartite motif-containing 3a	0.012
eng2a	engrailed 2a	0.012
spsb4b	splA/ryanodine receptor domain and SOCS box containing 4b	0.012
npc1	Niemann-Pick disease, type C1	0.012
smoc1	SPARC related modular calcium binding 1	0.012
foxj1a	forkhead box J1a	0.012
antxr1	anthrax toxin receptor 1	0.012
wu:fi40b06	wu:fi40b06	0.012
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.012
pcdh18a	protocadherin 18a	0.012
ythdf1	YTH domain family, member 1	0.012
eps8l3	EPS8-like 3	0.012
cables1	Cdk5 and Abl enzyme substrate 1	0.012
grem2	gremlin 2, cysteine knot superfamily	0.012
phox2a	paired-like homeobox 2a	0.012
esrrga	estrogen-related receptor gamma a	0.012
ggct	gamma-glutamyl cyclotransferase	0.012
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.012
faf1	Fas associated factor 1	0.012
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.012
unc45a	unc-45 homolog A (C. elegans)	0.012
abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.012
dlc	deltaC	0.011
lhfp	lipoma HMGIC fusion partner	0.011
nrarpa	notch-regulated ankyrin repeat protein a	0.011
cgnl1	cingulin-like 1	0.011
zc3h14	zinc finger CCCH-type containing 14	0.011
hoxb5a	homeo box B5a	0.011
kop	askopos	0.011
thoc2	THO complex 2	0.011
myl9l	myosin, light polypeptide 9, like	0.011
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.011	Zebrafish
hoxc1a	homeo box C1a	0.011
snai1a	snail homolog 1a (Drosophila)	0.011
itgb1b	integrin, beta 1b	0.011
myl7	myosin, light polypeptide 7, regulatory	0.011
arl13b	ADP-ribosylation factor-like 13b	0.011
elovl1a	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1a	0.011
szl	sizzled	0.011
gmnn	geminin, DNA replication inhibitor	0.011
gab1	GRB2-associated binding protein 1	0.011
epb4.1l4	erythrocyte protein band 4.1-like 4	0.011
smad1	MAD homolog 1 (Drosophila)	0.011
tgfb2	transforming growth factor, beta 2	0.011
ung	uracil-DNA glycosylase	0.011
tp63	tumor protein p63	0.011
emp2	epithelial membrane protein 2	0.011
irx3b	iroquois homeobox protein 3b	0.011
rargb	retinoic acid receptor, gamma b	0.011
bmp16	bone morphogenetic protein 16	0.011
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.011
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.011
LOC568379	von Willebrand factor A domain-containing protein 1-like	0.011
nrp1a	neuropilin 1a	0.011
col1a1b	collagen, type I, alpha 1b	0.011
anxa4	annexin A4	0.011
gli2a	GLI-Kruppel family member GLI2a	0.011
tsc22d3	TSC22 domain family, member 3	0.011
si:ch211-105d11.3	si:ch211-105d11.3	0.011
scube2	signal peptide, CUB domain, EGF-like 2	0.011
atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.011
fmnl2b	formin-like 2b	0.011
zgc:66100	zgc:66100	0.011
top2a	topoisomerase (DNA) II alpha	0.011
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.011
dao.2	D-amino-acid oxidase 2	0.011
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.011
stk25b	serine/threonine kinase 25b	0.011
cdk8	cyclin-dependent kinase 8	0.011
si:ch211-285f17.1	si:ch211-285f17.1	0.011
pacsin1b	protein kinase C and casein kinase substrate in neurons 1b	0.011
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.011
src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.010
hoxd11a	homeo box D11a	0.010
wu:fj62d01	wu:fj62d01	0.010
pdlim1	PDZ and LIM domain 1 (elfin)	0.010
ccdc65	coiled-coil domain containing 65	0.010
wdr45	WD repeat domain 45	0.010
mapk7	mitogen-activated protein kinase 7	0.010
usp20	ubiquitin specific protease 20	0.010
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.010
wipi2	WD repeat domain, phosphoinositide interacting 2	0.010
sf3b1	splicing factor 3b, subunit 1	0.010
siah1	seven in absentia homolog 1 (Drosophila)	0.010
frem3	Fras1 related extracellular matrix 3	0.010
cfdl	complement factor D (adipsin) like	0.010
gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.010
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.010
igf1rb	insulin-like growth factor 1b receptor	0.010
klf4a	Kruppel-like transcription factor 4a	0.010
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.010
and1	actinodin1	0.010
wu:fi36c02	wu:fi36c02	0.010
fgfr4	fibroblast growth factor receptor 4	0.010
sb:cb81	sb:cb81	0.010
cd9b	CD9 antigen, b	0.010
vamp3	vesicle-associated membrane protein 3 (cellubrevin)	0.010
ift88	intraflagellar transport 88 homolog	0.010
mobkl1aa	MOB1, Mps One Binder kinase activator-like 1A (yeast), genome duplicate a	0.010
wnt10b	wingless-type MMTV integration site family, member 10b	0.010	Zebrafish
sfrp2	secreted frizzled-related protein 2	0.010	Mouse