The network for 'regulation of gtpase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of gtpase activity

Any process that modulates the rate of GTP hydrolysis by a GTPase.

Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.999
PTK2 PTK2 protein tyrosine kinase 2 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.994
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.990
EGFR epidermal growth factor receptor 0.990
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.989
GRB7 growth factor receptor-bound protein 7 0.986
SFN stratifin 0.980
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.978
SH3KBP1 SH3-domain kinase binding protein 1 0.975
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.972
ITSN1 intersectin 1 (SH3 domain protein) 0.967
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.964
ARRB1 arrestin, beta 1 0.961
S100A6 S100 calcium binding protein A6 0.954
S100A8 S100 calcium binding protein A8 0.931
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.909
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.907
PLCG1 phospholipase C, gamma 1 0.889
DNM1 dynamin 1 0.879
S100A11 S100 calcium binding protein A11 0.877
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.876
S100B S100 calcium binding protein B 0.876
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.870
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.865
EXOSC3 exosome component 3 0.852
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.849
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.836
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.832
GRB2 growth factor receptor-bound protein 2 0.821
DNM2 dynamin 2 0.818
SH3RF1 SH3 domain containing ring finger 1 0.816
NCKAP1 NCK-associated protein 1 0.798
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.795
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.775
SNX9 sorting nexin 9 0.769
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.762
DOCK1 dedicator of cytokinesis 1 0.758
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.739
SOS1 son of sevenless homolog 1 (Drosophila) 0.739
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.725
TSC2 tuberous sclerosis 2 0.725
RIN3 Ras and Rab interactor 3 0.722
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.721
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.720
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.708
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.680
RHOA ras homolog gene family, member A 0.679
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.671
BCAR1 breast cancer anti-estrogen resistance 1 0.662
ILK integrin-linked kinase 0.661
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.657
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.650
JUN jun proto-oncogene 0.646
TMSB4X thymosin beta 4, X-linked 0.646
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.631
NCK2 NCK adaptor protein 2 0.617
NCF2 neutrophil cytosolic factor 2 0.614
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.610
TBCD tubulin folding cofactor D 0.593
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.583
TRAF5 TNF receptor-associated factor 5 0.572
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.568
CCR5 chemokine (C-C motif) receptor 5 0.559
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.557
UNC119 unc-119 homolog (C. elegans) 0.547
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.544
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.543
ADRBK1 adrenergic, beta, receptor kinase 1 0.525
ERBB2IP erbb2 interacting protein 0.521
FOS FBJ murine osteosarcoma viral oncogene homolog 0.513
GSK3B glycogen synthase kinase 3 beta 0.503
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.500
PLXNB1 plexin B1 0.495
RACGAP1 Rac GTPase activating protein 1 0.492
PKN3 protein kinase N3 0.492
LMNA lamin A/C 0.478
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.470
IGF1R insulin-like growth factor 1 receptor 0.462
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.457
RPLP1 ribosomal protein, large, P1 0.452
MYO9B myosin IXB 0.451
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.451
S100A9 S100 calcium binding protein A9 0.445
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.439
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.432
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.429
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.422
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.413
SYNJ1 synaptojanin 1 0.407
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.406
EMP3 epithelial membrane protein 3 0.404
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.398
FNBP1 formin binding protein 1 0.396
LMAN1 lectin, mannose-binding, 1 0.395
MPRIP myosin phosphatase Rho interacting protein 0.386
RND1 Rho family GTPase 1 0.385
RICTOR RPTOR independent companion of MTOR, complex 2 0.383
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.382
RAB1A RAB1A, member RAS oncogene family 0.382
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
CELE_F47G4.4 Protein F47G4.4 0.332
lag-1 Protein LAG-1 0.226
let-60 Protein LET-60 0.221
sem-5 Protein SEM-5 0.174
abl-1 Protein ABL-1 0.145
C11E4.6 Protein C11E4.6 0.120
mpk-1 Protein MPK-1 0.098
snf-1 Protein SNF-1 0.083
CELE_Y60A3A.9 Protein Y60A3A.9 0.082
itr-1 Protein ITR-1 0.081
rig-6 Protein RIG-6 0.075
F35G2.1 Protein F35G2.1 0.073
goa-1 Protein GOA-1 0.066
daf-19 Protein DAF-19 0.063
ykt-6 Protein YKT-6 0.061
unc-26 Protein UNC-26 0.060
bet-2 Protein BET-2 0.051
eor-2 Protein EOR-2 0.050
F40F4.7 Protein F40F4.7 0.048
zyg-9 Protein ZYG-9 0.047
tpxl-1 Protein TPXL-1 0.045
rps-2 Protein RPS-2 0.045
CELE_K08E7.6 Protein K08E7.6 0.044
zoo-1 Protein ZOO-1 0.043
unc-31 Protein UNC-31 0.043
CELE_T10D4.6 Protein T10D4.6 0.042
dgk-4 Protein DGK-4 0.042
stau-1 Protein STAU-1 0.042
nhl-3 Protein NHL-3 0.041
ric-8 Protein RIC-8 0.040
egrh-1 Protein EGRH-1 0.040
sym-4 Protein SYM-4 0.040
madf-5 Protein MADF-5 0.039
gap-2 Protein GAP-2 0.039
gly-7 Protein GLY-7 0.039
rpm-1 Protein RPM-1 0.038
egl-18 Protein EGL-18 0.038
unc-54 Protein UNC-54 0.038
rme-4 Protein RME-4 0.037
C27H2.2 Protein C27H2.2 0.037
ehs-1 Protein EHS-1 0.037
tpa-1 Protein TPA-1 0.037
atg-11 Protein ATG-11 0.036
gei-18 Protein GEI-18 0.035
sup-17 Protein SUP-17 0.034
unc-71 Protein UNC-71 0.034
plc-3 Protein PLC-3 0.034
rab-5 Protein RAB-5 0.034
C15H9.5 Protein C15H9.5 0.033
nrx-1 Protein NRX-1 0.032
unc-94 Protein UNC-94 0.032
sax-3 Protein SAX-3 0.032
afd-1 Protein AFD-1 0.031
unc-53 Protein UNC-53 0.031
rgs-7 Protein RGS-7 0.031
CELE_Y116A8C.26 Protein Y116A8C.26 0.030
rgs-6 Protein RGS-6 0.030
skn-1 Protein SKN-1 0.030
unc-15 Protein UNC-15 0.030
egl-26 Protein EGL-26 0.030
pat-3 Protein PAT-3 0.030
aap-1 Protein AAP-1 0.029
zyg-8 Protein ZYG-8 0.029
ptr-5 Protein PTR-5 0.029
gsk-3 Protein GSK-3 0.029
mei-1 Protein MEI-1 0.028
dpy-21 Protein DPY-21 0.028
nhr-10 Protein NHR-10 0.028
gar-3 Protein GAR-3 0.028
ddr-2 Protein DDR-2 0.028
nhr-4 Protein NHR-4 0.028
frm-7 Protein FRM-7 0.028
lec-1 Protein LEC-1 0.027
magi-1 Protein MAGI-1 0.027
cnt-2 Protein CNT-2 0.027
R90.1 Protein R90.1 0.027
egl-27 Protein EGL-27 0.027
vab-10 Protein VAB-10 0.027
kin-25 Protein KIN-25 0.027
F10C2.4 Protein F10C2.4 0.027
pdk-1 Protein PDK-1 0.026
dpy-27 Protein DPY-27 0.026
rgl-1 Protein RGL-1 0.026
sav-1 Protein SAV-1 0.026
cyld-1 Protein CYLD-1 0.026
CELE_F08D12.1 Protein F08D12.1 0.026
ttx-1 Protein TTX-1 0.026
egl-36 Protein EGL-36 0.026
pqe-1 Protein PQE-1 0.026
pps-1 Protein PPS-1 0.025
vav-1 Protein VAV-1 0.025
unc-79 Protein UNC-79 0.025
inx-18 Protein INX-18 0.025
glh-1 Protein GLH-1 0.024
sma-6 Protein SMA-6 0.024
sas-4 Protein SAS-4 0.024
aha-1 Protein AHA-1 0.024
gsa-1 Protein GSA-1 0.023
par-6 Protein PAR-6 0.023
T28B11.1 Protein T28B11.1 0.023
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Danio rerio
Name Description Probability Func Analog Organism
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.230
gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b 0.149
bida BH3 interacting domain death agonist 0.144
rtcd1 RNA terminal phosphate cyclase domain 1 0.136
adrb2a adrenergic receptor, beta 2a 0.132
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.130
tpm4 tropomyosin 4 0.129
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.128
mcl1b myeloid cell leukemia sequence 1b 0.102
plxnb2a plexin b2a 0.099
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.099
icn ictacalcin 0.099
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.096
zbtb4 zinc finger and BTB domain containing 4 0.093
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.084
mtdha metadherin a 0.081
cnn2 calponin 2 0.080
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.079
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.077
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.066
gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.065
zgc:56085 zgc:56085 0.065
im:7163548 im:7163548 0.064
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.062
zgc:77051 zgc:77051 0.061
acsl4a acyl-CoA synthetase long-chain family member 4a 0.060
stm starmaker 0.060
pak2a p21 (CDKN1A)-activated kinase 2a 0.058
s100a10b S100 calcium binding protein A10b 0.058
optc opticin 0.056
mcl1a myeloid cell leukemia sequence 1a 0.056
tp63 tumor protein p63 0.056
mat2a methionine adenosyltransferase II, alpha 0.056
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.055
gsna gelsolin a 0.054
vamp2 vesicle-associated membrane protein 2 0.053
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.052
msna moesin a 0.052
aldocb aldolase C, fructose-bisphosphate, b 0.052
rcv1 recoverin 0.052
gna14 guanine nucleotide binding protein (G protein), alpha 14 0.052
s100z S100 calcium binding protein Z 0.052
tm9sf2 transmembrane 9 superfamily member 2 0.052
depdc1a DEP domain containing 1a 0.051
rras related RAS viral (r-ras) oncogene homolog 0.051
psen1 presenilin 1 0.051
pdlim1 PDZ and LIM domain 1 (elfin) 0.050
arpc5a actin related protein 2/3 complex, subunit 5A 0.050
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.050
gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.050
sypl2b synaptophysin-like 2b 0.049
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.049
zeb1 zinc finger E-box binding homeobox 1 0.049
ttyh2l tweety homolog 2, like 0.048
efnb1 ephrin B1 0.048
LOC565839 tumor necrosis factor alpha-induced protein 2-like 0.047
scinlb scinderin like b 0.047
si:dkey-276i5.1 si:dkey-276i5.1 0.047
aqp3a aquaporin 3a 0.047
cfl2l cofilin 2, like 0.046
tbeta-a beta thymosin-like protein 2 0.045
zgc:73359 zgc:73359 0.045
syt5a synaptotagmin Va 0.045
gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 0.045
ncor1 nuclear receptor co-repressor 1 0.045
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.045
s100b S100 calcium binding protein, beta (neural) 0.044
fkbp5 FK506 binding protein 5 0.044
dusp6 dual specificity phosphatase 6 0.044
zgc:92360 zgc:92360 0.044
gclc glutamate-cysteine ligase, catalytic subunit 0.044
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.044
efna1b ephrin A1b 0.044
zgc:56466 zgc:56466 0.044
dclk2 doublecortin-like kinase 2 0.044
kif20bb kinesin family member 20Bb 0.044
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.044
slc25a3a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a 0.043
tm9sf4 transmembrane 9 superfamily protein member 4 0.043
im:7162646 im:7162646 0.043
guk1 guanylate kinase 1 0.043
vasp vasodilator-stimulated phosphoprotein 0.043
eprs glutamyl-prolyl-tRNA synthetase 0.043
m17 IL-6 subfamily cytokine M17 0.042
si:dkey-228g21.4 si:dkey-228g21.4 0.042
vmp1 vacuole membrane protein 1 0.042
hspa5 heat shock protein 5 0.042
farsb phenylalanyl-tRNA synthetase, beta subunit 0.041
cltca clathrin, heavy polypeptide a (Hc) 0.041
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.041
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.041
cldni claudin i 0.041
pvrl1b poliovirus receptor-related 1b 0.041
dzip1 DAZ interacting protein 1 0.041
yrk Yes-related kinase 0.041
pparg peroxisome proliferator activated receptor gamma 0.040
zgc:92392 zgc:92392 0.040
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.039
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.039
si:ch211-232m7.1 si:ch211-232m7.1 0.039
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.963
Pkn Protein kinase related to protein kinase N 0.826
Smox Smad on X 0.780
Pten CG5671 gene product from transcript CG5671-RB 0.483
CG8155 CG8155 gene product from transcript CG8155-RA 0.451
plexB plexin B 0.387
cno canoe 0.349
rok Rho-kinase 0.336
puc puckered 0.333
phl pole hole 0.325
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.320
Wnk CG7177 gene product from transcript CG7177-RA 0.302
Pk61C Protein kinase 61C 0.263
Rheb CG1081 gene product from transcript CG1081-RA 0.263
lgs legless 0.249
Ced-12 CG5336 gene product from transcript CG5336-RA 0.245
Khc Kinesin heavy chain 0.232
cta concertina 0.220
gek genghis khan 0.211
NaCP60E Na channel protein 60E 0.207
mbc myoblast city 0.206
stg string 0.175
Mtl Mig-2-like 0.165
baz bazooka 0.164
Sbf SET domain binding factor 0.161
sax saxophone 0.152
Pak3 CG14895 gene product from transcript CG14895-RA 0.141
mbt mushroom bodies tiny 0.133
l(2)k16918 lethal (2) k16918 0.127
ninaC neither inactivation nor afterpotential C 0.126
Apc APC-like 0.124
neur neuralized 0.122
Tak1 TGF-beta activated kinase 1 0.119
rdgA retinal degeneration A 0.117
CG6509 CG6509 gene product from transcript CG6509-RB 0.115
dnc dunce 0.108
Ephrin CG1862 gene product from transcript CG1862-RA 0.106
flw flapwing 0.105
Dhc64C Dynein heavy chain 64C 0.101
synj synaptojanin 0.099
CG1233 CG1233 gene product from transcript CG1233-RB 0.097
Stat92E Signal-transducer and activator of transcription protein at 92E 0.095
cenG1A centaurin gamma 1A 0.094
Rtnl1 CG33113 gene product from transcript CG33113-RF 0.087
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.085
ttk tramtrack 0.084
siz schizo 0.081
trio CG18214 gene product from transcript CG18214-RA 0.079
schlank CG3576 gene product from transcript CG3576-RB 0.079
sima similar 0.078
cher cheerio 0.078
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.078
dos daughter of sevenless 0.076
Hr96 Hormone receptor-like in 96 0.076
CG9894 CG9894 gene product from transcript CG9894-RB 0.074
stai stathmin 0.072
insc inscuteable 0.071
CG3573 CG3573 gene product from transcript CG3573-RA 0.070
ck crinkled 0.068
rdgC retinal degeneration C 0.067
CalpB Calpain-B 0.065
drpr draper 0.065
CG8334 CG8334 gene product from transcript CG8334-RA 0.064
CG5798 CG5798 gene product from transcript CG5798-RA 0.064
Hem HEM-protein 0.062
gig gigas 0.061
UBL3 CG9038 gene product from transcript CG9038-RC 0.061
Prp31 CG6876 gene product from transcript CG6876-RA 0.061
CG17233 CG17233 gene product from transcript CG17233-RA 0.061
ird1 immune response deficient 1 0.060
l(3)05822 lethal (3) 05822 0.060
mys myospheroid 0.060
Dok Downstream of kinase 0.059
Ras85D Ras oncogene at 85D 0.059
RhoBTB CG5701 gene product from transcript CG5701-RA 0.059
Su(H) Suppressor of Hairless 0.058
Myo31DF Myosin 31DF 0.058
Sin3A CG8815 gene product from transcript CG8815-RC 0.057
Dab Disabled 0.056
Mad Mothers against dpp 0.056
raps rapsynoid 0.055
mago mago nashi 0.055
CG11033 CG11033 gene product from transcript CG11033-RB 0.054
Lar Leukocyte-antigen-related-like 0.054
px plexus 0.054
p120ctn Adherens junction protein p120 0.053
CG4552 CG4552 gene product from transcript CG4552-RA 0.053
SNF1A SNF1A/AMP-activated protein kinase 0.053
Galpha49B G protein alpha49B 0.053
Cad87A CG6977 gene product from transcript CG6977-RA 0.052
Tsc1 CG6147 gene product from transcript CG6147-RA 0.052
Gyc76C Guanylyl cyclase at 76C 0.050
CG3558 CG3558 gene product from transcript CG3558-RC 0.050
Pli Pellino 0.050
Hph HIF prolyl hydroxylase 0.049
Tre1 trapped in endoderm-1 0.049
Jra Jun-related antigen 0.048
alpha-Man-IIb CG4606 gene product from transcript CG4606-RA 0.047
Flo-2 flotillin 2 0.046
mop myopic 0.046
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.241
Hk1 hexokinase 1 0.155
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.122
Tgfbr2 transforming growth factor, beta receptor II 0.098
Gria2 glutamate receptor, ionotropic, AMPA 2 0.095
Dlg3 discs, large homolog 3 (Drosophila) 0.092
Gipc1 GIPC PDZ domain containing family, member 1 0.078
Sstr1 somatostatin receptor 1 0.076
Lcp2 lymphocyte cytosolic protein 2 0.068
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.067
Dapk3 death-associated protein kinase 3 0.067
Wdr7 WD repeat domain 7 0.063
Copb1 coatomer protein complex, subunit beta 1 0.063
Amph amphiphysin 0.063
Scn3b sodium channel, voltage-gated, type III, beta 0.063
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.061
Adora2a adenosine A2a receptor 0.059
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.058
Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 0.058
Tek TEK tyrosine kinase, endothelial 0.058
Ptprn2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.057
Sdc3 syndecan 3 0.056
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.054
Adora1 adenosine A1 receptor 0.053
Dock9 dedicator of cytokinesis 9 0.053
Plekhn1 pleckstrin homology domain containing, family N member 1 0.052
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.052
Shank2 SH3 and multiple ankyrin repeat domains 2 0.051
Klf6 Kruppel-like factor 6 0.051
Errfi1 ERBB receptor feedback inhibitor 1 0.051
Homer1 homer homolog 1 (Drosophila) 0.050
Adrbk1 adrenergic, beta, receptor kinase 1 0.049
Mapk7 mitogen-activated protein kinase 7 0.048
Scarb1 scavenger receptor class B, member 1 0.047
A4galt alpha 1,4-galactosyltransferase 0.047
Anxa2 annexin A2 0.046
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.045
Plcg1 phospholipase C, gamma 1 0.045
Pld2 phospholipase D2 0.045
Fgfr2 fibroblast growth factor receptor 2 0.044
Akap1 A kinase (PRKA) anchor protein 1 0.044
Rap1b RAP1B, member of RAS oncogene family 0.044
Ptafr platelet-activating factor receptor 0.044
Abr active BCR-related gene 0.044
Cyfip2 cytoplasmic FMR1 interacting protein 2 0.043
Camk4 calcium/calmodulin-dependent protein kinase IV 0.042
Pcnxl3 pecanex-like 3 (Drosophila) 0.041
Epas1 endothelial PAS domain protein 1 0.041
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.041
Epb41l1 erythrocyte membrane protein band 4.1-like 1 0.041
Dgkz diacylglycerol kinase zeta 0.041
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.041
Braf v-raf murine sarcoma viral oncogene homolog B1 0.040
Dnm1 dynamin 1 0.040
Med23 mediator complex subunit 23 0.039
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.039
Robo2 roundabout homolog 2 (Drosophila) 0.039
Fmnl1 formin-like 1 0.039
Znf692 zinc finger protein 692 0.039
Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 0.038
Vamp3 vesicle-associated membrane protein 3 0.038
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.038
Mcpt4 mast cell protease 4 0.038
Sept10 septin 10 0.038
Syn1 synapsin I 0.037
Fgfr1 Fibroblast growth factor receptor 1 0.037
Mmp17 matrix metallopeptidase 17 0.036
Cfp complement factor properdin 0.036
Svop SV2 related protein 0.036
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.035
RGD1308350 similar to hypothetical protein MGC13251 0.035
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.035
RGD1309414 similar to KIAA0913 protein 0.035
Susd3 sushi domain containing 3 0.034
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.034
Cnksr2 connector enhancer of kinase suppressor of Ras 2 0.034
Vps52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.033
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.033
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.033
Tsc2 tuberous sclerosis 2 0.033
Agrn agrin 0.033
Ncf4 neutrophil cytosolic factor 4 0.033
Clcn2 chloride channel 2 0.033
Jdp2 Jun dimerization protein 2 0.032
Prkcb protein kinase C, beta 0.032
Pde2a phosphodiesterase 2A, cGMP-stimulated 0.032
Lpcat4 lysophosphatidylcholine acyltransferase 4 0.032
Clasp1 cytoplasmic linker associated protein 1 0.032
Phc1 polyhomeotic homolog 1 (Drosophila) 0.032
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.032
Chn1 chimerin (chimaerin) 1 0.032
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.031
Zfp384 zinc finger protein 384 0.031
Cyth1 cytohesin 1 0.031
Fam108a1 family with sequence similarity 108, member A1 0.031
Ephb1 Eph receptor B1 0.030
Map2k2 mitogen activated protein kinase kinase 2 0.030
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.030
Clcn7 chloride channel 7 0.030
Abcf3 ATP-binding cassette, subfamily F (GCN20), member 3 0.029
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GYL1 Gyl1p 0.603
STE5 Ste5p 0.554
MKK1 Mkk1p 0.509
GCD6 Gcd6p 0.482
RHO1 Rho1p 0.398
VPS15 Vps15p 0.282
TRS65 Trs65p 0.270
CDC24 Cdc24p 0.257
STE4 Ste4p 0.234
GIC2 Gic2p 0.233
IRA1 Ira1p 0.217
STE11 Ste11p 0.212
ROM2 Rom2p 0.205
GCD7 Gcd7p 0.173
FKH1 Fkh1p 0.169
GDI1 Gdi1p 0.156
PKC1 Pkc1p 0.147
SPA2 Spa2p 0.145
AVO1 Avo1p 0.130
KOG1 Kog1p 0.122
FYV8 Fyv8p 0.121
MDS3 Mds3p 0.120
BET3 Bet3p 0.113
TCO89 Tco89p 0.106
SLT2 Slt2p 0.103
ATG14 Atg14p 0.094
INP53 Inp53p 0.094
TOM1 Tom1p 0.093
YPT53 Ypt53p 0.090
RFC1 Rfc1p 0.087
BEM3 Bem3p 0.078
YPT52 Ypt52p 0.076
FAR1 Far1p 0.076
VPS38 Vps38p 0.072
SEC16 Sec16p 0.069
MSB3 Msb3p 0.063
TOR2 Tor2p 0.062
GPB2 Gpb2p 0.061
PEA2 Pea2p 0.061
RGD2 Rgd2p 0.060
YIP3 Yip3p 0.060
FUS2 Fus2p 0.058
CYK3 Cyk3p 0.055
SSK1 Ssk1p 0.054
STE2 Ste2p 0.050
SRP54 Srp54p 0.050
RGD1 Rgd1p 0.049
MRS6 Mrs6p 0.049
PRS2 Prs2p 0.045
VPS41 Vps41p 0.045
ARP10 Arp10p 0.044
ENT2 Ent2p 0.043
SSK2 Ssk2p 0.043
MNN9 Mnn9p 0.041
SVF1 Svf1p 0.041
SUI3 Sui3p 0.041
SEC53 Sec53p 0.040
YMR1 Ymr1p 0.040
SIA1 Sia1p 0.040
TSR1 Tsr1p 0.040
FMS1 Fms1p 0.039
KEL1 Kel1p 0.039
CCZ1 Ccz1p 0.039
KSS1 Kss1p 0.038
CDC25 Cdc25p 0.038
FUS1 Fus1p 0.037
SNX41 Snx41p 0.037
ATG13 Atg13p 0.037
SUI2 Sui2p 0.037
TOR1 Tor1p 0.036
MSP1 Msp1p 0.036
DCD1 Dcd1p 0.036
YIL055C hypothetical protein 0.036
URA6 Ura6p 0.036
NVJ1 Nvj1p 0.036
BRN1 Brn1p 0.035
TRS120 Trs120p 0.035
CLN3 Cln3p 0.035
PPE1 Ppe1p 0.035
YDR186C hypothetical protein 0.035
TRS31 Trs31p 0.034
PEP5 Pep5p 0.034
HYP2 Hyp2p 0.034
YGR126W hypothetical protein 0.033
NEO1 Neo1p 0.033
MSC7 Msc7p 0.033
PTP2 Ptp2p 0.033
BIT61 Bit61p 0.033
SPR6 Spr6p 0.033
MBF1 Mbf1p 0.033
FAA2 Faa2p 0.033
RRI1 Rri1p 0.033
ATG20 Atg20p 0.032
YDL206W hypothetical protein 0.032
YLR257W hypothetical protein 0.032
VPS74 Vps74p 0.032
TUS1 Tus1p 0.032
SAR1 Sar1p 0.032
YGK3 Ygk3p 0.032
DPB4 Dpb4p 0.031