The network for 'regulation of mononuclear cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mononuclear cell proliferation

Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.

Name Description Probability Func Analog Organism
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.997
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.992
LCK lymphocyte-specific protein tyrosine kinase 0.990
FGFR2 fibroblast growth factor receptor 2 0.982
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.981
TRAF1 TNF receptor-associated factor 1 0.977
LAT linker for activation of T cells 0.945
BIRC3 baculoviral IAP repeat containing 3 0.934
CD80 CD80 molecule 0.933
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.927
HLA-F major histocompatibility complex, class I, F 0.898
B2M beta-2-microglobulin 0.896
SYK spleen tyrosine kinase 0.888
HLA-DRA major histocompatibility complex, class II, DR alpha 0.887
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.887
ICAM1 intercellular adhesion molecule 1 0.855
HLA-G major histocompatibility complex, class I, G 0.849
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.840
PTPRC protein tyrosine phosphatase, receptor type, C 0.829
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.817
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.816
HLA-B major histocompatibility complex, class I, B 0.803
CD2 CD2 molecule 0.797
BTN3A3 butyrophilin, subfamily 3, member A3 0.797
HLA-DMA major histocompatibility complex, class II, DM alpha 0.776
CCR5 chemokine (C-C motif) receptor 5 0.776
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.774
IL4R interleukin 4 receptor 0.767
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.720
SOCS3 suppressor of cytokine signaling 3 0.705
BTN3A1 butyrophilin, subfamily 3, member A1 0.703
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.702
GRB2 growth factor receptor-bound protein 2 0.644
IL10RA interleukin 10 receptor, alpha 0.644
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.630
IL1R1 interleukin 1 receptor, type I 0.602
CD247 CD247 molecule 0.593
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.583
BCL2L1 BCL2-like 1 0.578
TANK TRAF family member-associated NFKB activator 0.577
JAK1 Janus kinase 1 0.577
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.569
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.567
CXCL9 chemokine (C-X-C motif) ligand 9 0.554
BCL2 B-cell CLL/lymphoma 2 0.552
BTN3A2 butyrophilin, subfamily 3, member A2 0.551
IL2RB interleukin 2 receptor, beta 0.542
ABI1 abl-interactor 1 0.540
CD1C CD1c molecule 0.534
CCL4 chemokine (C-C motif) ligand 4 0.531
CD86 CD86 molecule 0.527
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.523
CCR7 chemokine (C-C motif) receptor 7 0.518
IRF4 interferon regulatory factor 4 0.516
IL1B interleukin 1, beta 0.501
HLA-E major histocompatibility complex, class I, E 0.482
CD40 CD40 molecule, TNF receptor superfamily member 5 0.482
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.472
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.457
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.444
HLA-C major histocompatibility complex, class I, C 0.443
IL8 interleukin 8 0.439
FASLG Fas ligand (TNF superfamily, member 6) 0.435
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.428
SIGLEC7 sialic acid binding Ig-like lectin 7 0.412
EGFR epidermal growth factor receptor 0.411
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.393
BRCA1 breast cancer 1, early onset 0.392
FGF1 fibroblast growth factor 1 (acidic) 0.383
TRAF3 TNF receptor-associated factor 3 0.375
HLA-A major histocompatibility complex, class I, A 0.374
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.373
IL2RG interleukin 2 receptor, gamma 0.353
STAT4 signal transducer and activator of transcription 4 0.348
TICAM2 toll-like receptor adaptor molecule 2 0.336
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.321
SH2D1A SH2 domain containing 1A 0.308
CXCL10 chemokine (C-X-C motif) ligand 10 0.307
CD33 CD33 molecule 0.305
CCR1 chemokine (C-C motif) receptor 1 0.301
IFNG interferon, gamma 0.297
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.295
IFNGR1 interferon gamma receptor 1 0.292
CFLAR CASP8 and FADD-like apoptosis regulator 0.291
CCL8 chemokine (C-C motif) ligand 8 0.290
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.279
BTK Bruton agammaglobulinemia tyrosine kinase 0.276
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.274
PAX3 paired box 3 0.272
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.271
LST1 leukocyte specific transcript 1 0.270
PILRA paired immunoglobin-like type 2 receptor alpha 0.269
MYD88 myeloid differentiation primary response gene (88) 0.269
IL10 interleukin 10 0.268
IGF2 insulin-like growth factor 2 (somatomedin A) 0.261
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.259
SOS1 son of sevenless homolog 1 (Drosophila) 0.257
TFF1 trefoil factor 1 0.255
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.247
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.245
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Da RT1 class II, locus Da 0.881
RT1-Ba RT1 class II, locus Ba 0.873
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.836
Cd247 Cd247 molecule 0.759
Cd37 CD37 molecule 0.714
RT1-Db1 RT1 class II, locus Db1 0.555
RT1-Bb RT1 class II, locus Bb 0.533
RT1-DMb RT1 class II, locus DMb 0.502
RT1-DMa RT1 class II, locus DMa 0.393
Ptprc protein tyrosine phosphatase, receptor type, C 0.227
Lyz2 lysozyme 2 0.210
Inpp5d inositol polyphosphate-5-phosphatase D 0.187
Hck hemopoietic cell kinase 0.147
Ciita class II, major histocompatibility complex, transactivator 0.122
Cd44 Cd44 molecule 0.122
Arpc1b actin related protein 2/3 complex, subunit 1B 0.118
Laptm5 lysosomal protein transmembrane 5 0.116
Cd53 Cd53 molecule 0.114
Aif1 allograft inflammatory factor 1 0.110
Apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.085
Il18 interleukin 18 0.083
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.082
Il1b interleukin 1 beta 0.076
Cd2 Cd2 molecule 0.075
Gzmk granzyme K 0.072
Serpinb1a serine (or cysteine) proteinase inhibitor, clade B, member 1a 0.071
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.062
Anxa2 annexin A2 0.060
Casp1 caspase 1 0.054
Ccr5 chemokine (C-C motif) receptor 5 0.053
Il6 interleukin 6 0.053
Il10 interleukin 10 0.051
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.050
Met met proto-oncogene 0.046
Spn sialophorin 0.043
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.043
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.042
Csn2 casein beta 0.041
C1qb complement component 1, q subcomponent, B chain 0.040
Il7r interleukin 7 receptor 0.039
Il2rb interleukin 2 receptor, beta 0.038
Cd38 CD38 molecule 0.038
Nkg7 natural killer cell group 7 sequence 0.038
Reg3g regenerating islet-derived 3 gamma 0.037
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.037
Smgb neonatal submandibular gland protein B 0.037
MGC112715 hypothetical protein LOC690899 0.037
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.036
Lcp2 lymphocyte cytosolic protein 2 0.036
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.036
Cfp complement factor properdin 0.036
Tacr2 tachykinin receptor 2 0.035
Mmp10 matrix metallopeptidase 10 0.035
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.035
Prss3 protease, serine, 3 0.034
Slfn2 schlafen 2 0.034
Scn11a sodium channel, voltage-gated, type XI, alpha 0.034
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.033
Napsa napsin A aspartic peptidase 0.033
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.031
Vip vasoactive intestinal peptide 0.030
Cd5 Cd5 molecule 0.030
Il1rl1 interleukin 1 receptor-like 1 0.030
Gpr20 G protein-coupled receptor 20 0.030
Lcp1 lymphocyte cytosolic protein 1 0.029
Il1r1 interleukin 1 receptor, type I 0.029
Tas2r123 taste receptor, type 2, member 123 0.029
Lef1 lymphoid enhancer binding factor 1 0.029
Pde3a phosphodiesterase 3A, cGMP inhibited 0.029
Arhgap4 Rho GTPase activating protein 4 0.027
Krt14 keratin 14 0.027
Ctss cathepsin S 0.027
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.027
Socs3 suppressor of cytokine signaling 3 0.027
Ret ret proto-oncogene 0.026
Prl7a4 prolactin family 7, subfamily a, member 4 0.026
Grn granulin 0.026
Sell selectin L 0.026
Cd4 Cd4 molecule 0.025
Map4k1 mitogen activated protein kinase kinase kinase kinase 1 0.025
Ccl3 chemokine (C-C motif) ligand 3 0.025
Psd4 pleckstrin and Sec7 domain containing 4 0.025
Capg capping protein (actin filament), gelsolin-like 0.025
Bin2 bridging integrator 2 0.025
Hpx hemopexin 0.024
Cd86 CD86 molecule 0.024
Fgfr2 fibroblast growth factor receptor 2 0.024
Cd22 CD22 molecule 0.024
Calcrl calcitonin receptor-like 0.024
Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.024
Ncr1 natural cytotoxicity triggering receptor 1 0.023
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.023
Sash3 SAM and SH3 domain containing 3 0.023
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.023
Anxa1 annexin A1 0.023
Fam108b1 family with sequence similarity 108, member B1 0.022
Vav1 vav 1 guanine nucleotide exchange factor 0.022
Impg2 interphotoreceptor matrix proteoglycan 2 0.022
Mos Moloney sarcoma oncogene 0.022
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.022
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism