The network for 'canonical wnt signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

canonical wnt signaling pathway

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.

Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Shh sonic hedgehog 0.999
Fgfr2 fibroblast growth factor receptor 2 0.999
Tbx3 T-box 3 0.999
Gli3 GLI-Kruppel family member GLI3 0.998
Vangl2 vang-like 2 (van gogh, Drosophila) 0.997
Pitx2 paired-like homeodomain transcription factor 2 0.996
Nodal nodal 0.988
Pten phosphatase and tensin homolog 0.980
Otx2 orthodenticle homolog 2 (Drosophila) 0.978
Wnt3a wingless-related MMTV integration site 3A 0.978
Wnt5a wingless-related MMTV integration site 5A 0.977
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.977
Ntf3 neurotrophin 3 0.969
Fgf10 fibroblast growth factor 10 0.967
Sox9 SRY-box containing gene 9 0.961
Lrp6 low density lipoprotein receptor-related protein 6 0.959
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.952
Mapk14 mitogen-activated protein kinase 14 0.938
Pitx1 paired-like homeodomain transcription factor 1 0.938
Pax2 paired box gene 2 0.931
Pax8 paired box gene 8 0.929
Gsk3b glycogen synthase kinase 3 beta 0.927
Pax3 paired box gene 3 0.921
Pthlh parathyroid hormone-like peptide 0.918
Ar androgen receptor 0.917
Msx1 homeobox, msh-like 1 0.917
Fgf8 fibroblast growth factor 8 0.912
Hoxd11 homeobox D11 0.904
Foxc2 forkhead box C2 0.901
Axin1 axin 1 0.897
Lhx1 LIM homeobox protein 1 0.886
Esr1 estrogen receptor 1 (alpha) 0.881
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.877
Smad6 MAD homolog 6 (Drosophila) 0.871
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.863
Notch1 Notch gene homolog 1 (Drosophila) 0.862
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.851
Gli2 GLI-Kruppel family member GLI2 0.840
Sox2 SRY-box containing gene 2 0.839
Lef1 lymphoid enhancer binding factor 1 0.833
Rac1 RAS-related C3 botulinum substrate 1 0.823
Apc adenomatosis polyposis coli 0.823
Wnt6 wingless-related MMTV integration site 6 0.811
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.793
Emx2 empty spiracles homolog 2 (Drosophila) 0.786
Hand1 heart and neural crest derivatives expressed transcript 1 0.771
Meox2 mesenchyme homeobox 2 0.761
Hoxd13 homeobox D13 0.757
Hes1 hairy and enhancer of split 1 (Drosophila) 0.753
Pou3f3 POU domain, class 3, transcription factor 3 0.748
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.748
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.720
Efs embryonal Fyn-associated substrate 0.719
Wnt4 wingless-related MMTV integration site 4 0.718
Pax6 paired box gene 6 0.716
Amhr2 anti-Mullerian hormone type 2 receptor 0.704
Bmp4 bone morphogenetic protein 4 0.696
Atf2 activating transcription factor 2 0.695
Axin2 axin2 0.693
Smad3 MAD homolog 3 (Drosophila) 0.689
Foxc1 forkhead box C1 0.687
Smo smoothened homolog (Drosophila) 0.687
Prrx1 paired related homeobox 1 0.681
Ahr aryl-hydrocarbon receptor 0.673
Vangl1 vang-like 1 (van gogh, Drosophila) 0.671
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.657
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.654
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.636
Ednrb endothelin receptor type B 0.634
Wwtr1 WW domain containing transcription regulator 1 0.634
Grb2 growth factor receptor bound protein 2 0.628
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.613
Tbx5 T-box 5 0.609
Sfrp2 secreted frizzled-related protein 2 0.607
Fgfr1 fibroblast growth factor receptor 1 0.605
Crebbp CREB binding protein 0.605
Dll1 delta-like 1 (Drosophila) 0.602
Pgr progesterone receptor 0.596
Tbx2 T-box 2 0.588
Insm1 insulinoma-associated 1 0.582
Kiss1 KiSS-1 metastasis-suppressor 0.576
Nog noggin 0.575
Trp63 transformation related protein 63 0.573
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.569
Sim2 single-minded homolog 2 (Drosophila) 0.569
Lhx9 LIM homeobox protein 9 0.567
Ghr growth hormone receptor 0.565
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.562
Pou5f1 POU domain, class 5, transcription factor 1 0.558
Pkd2 polycystic kidney disease 2 0.557
Scn5a sodium channel, voltage-gated, type V, alpha 0.555
Tbx15 T-box 15 0.550
Cbl Casitas B-lineage lymphoma 0.544
Lhx3 LIM homeobox protein 3 0.544
Trp53 transformation related protein 53 0.540
Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.540
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.538
Zeb1 zinc finger E-box binding homeobox 1 0.517
Mapk8 mitogen-activated protein kinase 8 0.517
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-30 Protein EGL-30 0.342
egl-18 Protein EGL-18 0.333
eor-1 Protein EOR-1 0.327
pry-1 Protein PRY-1 0.291
wrm-1 Protein WRM-1 0.248
attf-4 Protein ATTF-4 0.247
smp-1 Protein SMP-1 0.220
lin-36 Protein LIN-36 0.206
CELE_C46H3.2 Protein C46H3.2 0.190
hmr-1 Protein HMR-1 0.178
cst-1 Protein CST-1 0.175
attf-2 Protein ATTF-2 0.171
F10G8.8 Protein F10G8.8 0.161
let-60 Protein LET-60 0.158
mom-2 Protein MOM-2 0.154
cki-2 Protein CKI-2 0.153
ham-1 Protein HAM-1 0.149
cst-2 Protein CST-2 0.136
F28B3.1 Protein F28B3.1 0.135
unc-60 Protein UNC-60 0.128
axl-1 Protein AXL-1 0.123
vang-1 Protein VANG-1 0.122
igcm-4 Protein IGCM-4 0.119
mig-38 Protein MIG-38 0.119
xpo-1 Protein XPO-1 0.118
nhr-25 Protein NHR-25 0.118
flh-1 Protein FLH-1 0.117
inx-3 Protein INX-3 0.115
trim-9 Protein TRIM-9 0.110
lsd-1 Protein LSD-1 0.107
lit-1 Protein LIT-1 0.107
lin-17 Protein LIN-17 0.105
sel-12 Protein SEL-12 0.103
pop-1 Protein POP-1 0.103
lsy-2 Protein LSY-2 0.100
sel-8 Protein SEL-8 0.099
hid-1 Protein HID-1 0.098
ncam-1 Protein NCAM-1 0.098
T28F4.1 Protein T28F4.1 0.098
dpy-22 Protein DPY-22 0.097
swan-1 Protein SWAN-1 0.095
T14G11.1 Protein T14G11.1 0.094
mes-3 Protein MES-3 0.094
let-526 Protein LET-526 0.094
rig-6 Protein RIG-6 0.093
F13C5.2 Protein F13C5.2 0.089
zyg-8 Protein ZYG-8 0.088
R09A1.3 Protein R09A1.3 0.087
ceh-32 Protein CEH-32 0.086
R10E12.2 Protein R10E12.2 0.086
dma-1 Protein DMA-1 0.086
somi-1 Protein SOMI-1 0.085
madf-5 Protein MADF-5 0.081
daf-12 Protein DAF-12 0.080
elt-6 Protein ELT-6 0.079
lsy-12 Protein LSY-12 0.078
tra-2 Protein TRA-2 0.078
dpl-1 Protein DPL-1 0.077
eya-1 Protein EYA-1 0.077
klp-18 Protein KLP-18 0.077
unc-5 Protein UNC-5 0.076
aha-1 Protein AHA-1 0.075
scd-1 Protein SCD-1 0.075
nhr-1 Protein NHR-1 0.074
F13H8.2 Protein F13H8.2 0.074
F22D3.2 Protein F22D3.2 0.073
lin-11 Protein LIN-11 0.072
daf-3 Protein DAF-3 0.072
unc-73 Protein UNC-73 0.072
gon-2 Protein GON-2 0.071
lin-23 Protein LIN-23 0.071
unc-45 Protein UNC-45 0.069
hlh-1 Protein HLH-1 0.069
nhr-49 Protein NHR-49 0.069
bam-2 Protein BAM-2 0.066
tag-51 Protein TAG-51 0.066
gon-4 Protein GON-4 0.066
glp-1 Protein GLP-1 0.066
sax-3 Protein SAX-3 0.065
CELE_Y50E8A.5 Protein Y50E8A.5 0.062
sma-6 Protein SMA-6 0.061
magi-1 Protein MAGI-1 0.061
elc-1 Protein ELC-1 0.061
ceh-27 Protein CEH-27 0.061
mig-2 Protein MIG-2 0.060
Y65A5A.1 Protein Y65A5A.1 0.060
dsh-2 Protein DSH-2 0.060
hil-3 Protein HIL-3 0.060
C27C12.1 Protein C27C12.1 0.058
kal-1 Protein KAL-1 0.058
ptp-3 Protein PTP-3 0.058
bli-1 Protein BLI-1 0.058
rgs-7 Protein RGS-7 0.058
CELE_F32A7.5 Protein F32A7.5 0.058
ldb-1 Protein LDB-1 0.058
CELE_F07E5.5 Protein F07E5.5 0.058
K01A2.9 Protein K01A2.9 0.057
atg-18 Protein ATG-18 0.057
T09B4.5 Protein T09B4.5 0.057
tos-1 Protein TOS-1 0.056
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Danio rerio
Name Description Probability Func Analog Organism
wnt5b wingless-type MMTV integration site family, member 5b 0.908
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.897
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.848
axin2 axin 2 (conductin, axil) 0.820
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.732
wnt4a wingless-type MMTV integration site family, member 4a 0.721
pou5f1 POU domain, class 5, transcription factor 1 0.598
tbx1 T-box 1 0.585
wnt11 wingless-type MMTV integration site family, member 11 0.577
flt4 fms-related tyrosine kinase 4 0.567
dusp6 dual specificity phosphatase 6 0.494
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.475
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.474
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.473
lef1 lymphocyte enhancer binding factor 1 0.470
notch1a notch homolog 1a 0.414
sox19a SRY-box containing gene 19a 0.411
ephb4b eph receptor B4b 0.388
per3 period homolog 3 (Drosophila) 0.371
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.364
wls wntless homolog (Drosophila) 0.363
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.359
fzd7b frizzled homolog 7b 0.327
dharma dharma 0.322
wnt1 wingless-type MMTV integration site family, member 1 0.320
fzd7a frizzled homolog 7a 0.317
lrp2 low density lipoprotein-related protein 2 0.315
wnt11r wingless-type MMTV integration site family, member 11, related 0.312
snai1b snail homolog 1b (Drosophila) 0.307
wnt8a wingless-type MMTV integration site family, member 8a 0.297
crb2a crumbs homolog 2a 0.288
rspo3 R-spondin 3 homolog (Xenopus laevis) 0.288
igf1rb insulin-like growth factor 1b receptor 0.272
mib mind bomb 0.270
axin1 axin 1 0.268
gata6 GATA-binding protein 6 0.265
col1a2 collagen, type I, alpha 2 0.252
col1a1a collagen, type I, alpha 1a 0.248
cfl2l cofilin 2, like 0.236
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.235
chsy1 chondroitin sulfate synthase 1 0.225
fzd8a frizzled homolog 8a 0.221
gdf6a growth differentiation factor 6a 0.217
fn1 fibronectin 1 0.206
rest RE1-silencing transcription factor 0.196
ptch1 patched 1 0.189
il17rd interleukin 17 receptor D 0.185
inka1a induced in neural crest by AP2, 1a 0.180
crabp2b cellular retinoic acid binding protein 2, b 0.178
twist3 twist3 0.173
tp53 tumor protein p53 0.167
six1b sine oculis homeobox homolog 1b 0.163
zbtb4 zinc finger and BTB domain containing 4 0.162
vent ventral expressed homeobox 0.156
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.153
sparc secreted acidic cysteine rich glycoprotein 0.152
gpc4 glypican 4 0.151
wnt3a wingless-type MMTV integration site family, member 3A 0.150
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.145
znf703 zinc finger protein 703 0.142
spry2 sprouty homolog 2 0.142
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.141
foxg1a forkhead box G1a 0.139
wnt3 wingless-type MMTV integration site family, member 3 0.138
epha4b eph receptor A4b 0.137
foxb1.2 forkhead box B1.2 0.135
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.135
zic5 zic family member 5 (odd-paired homolog, Drosophila) 0.132
irx5a iroquois homeobox protein 5a 0.131
sox2 SRY-box containing gene 2 0.131
sox3 SRY-box containing gene 3 0.128
znf503 zinc finger protein 503 0.128
smo smoothened homolog (Drosophila) 0.125
brd4 bromodomain containing 4 0.120
ndr2 nodal-related 2 0.119
nkx6.2 NK6 transcription factor related, locus 2 0.117
fgfr1a fibroblast growth factor receptor 1a 0.116
sox11b SRY-box containing gene 11b 0.114
ggnbp2 gametogenetin binding protein 2 0.113
sox19b SRY-box containing gene 19b 0.112
sp5l Sp5 transcription factor-like 0.109
cobl cordon-bleu homolog (mouse) 0.109
vsx1 visual system homeobox 1 homolog, chx10-like 0.108
tpbgl trophoblast glycoprotein-like 0.107
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.104
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.104
ptpra protein tyrosine phosphatase, receptor type, A 0.103
etv2 ets variant gene 2 0.098
pea3 ETS-domain transcription factor pea3 0.096
hs6st1b heparan sulfate 6-O-sulfotransferase 1b 0.096
lhx2b LIM homeobox 2b 0.096
lfng lunatic fringe homolog 0.096
wnt9b wingless-type MMTV integration site family, member 9B 0.095
oep one-eyed pinhead 0.094
tpm4 tropomyosin 4 0.091
aplnra apelin receptor a 0.091
gli1 GLI-Kruppel family member 1 0.090
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.086
sfrp1a secreted frizzled-related protein 1a 0.086
neo1 neogenin 1 0.086
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Drosophila melanogaster
Name Description Probability Func Analog Organism
wg wingless 0.995
vg vestigial 0.732
Ras85D Ras oncogene at 85D 0.636
shn schnurri 0.587
fz frizzled 0.555
bsk basket 0.500
ovo CG6824 gene product from transcript CG6824-RE 0.432
dsh dishevelled 0.429
ago archipelago 0.416
skd skuld 0.335
bai baiser 0.289
hep hemipterous 0.274
ex expanded 0.272
ci cubitus interruptus 0.265
EndoGI Endonuclease G inhibitor 0.251
wdb widerborst 0.182
sfl sulfateless 0.169
mts microtubule star 0.167
sgl sugarless 0.167
polo CG12306 gene product from transcript CG12306-RA 0.163
hh hedgehog 0.156
Ptp69D Protein tyrosine phosphatase 69D 0.150
Rac1 CG2248 gene product from transcript CG2248-RA 0.147
cos costa 0.143
Pka-C1 cAMP-dependent protein kinase 1 0.140
sr stripe 0.136
CG9053 CG9053 gene product from transcript CG9053-RA 0.135
Akt1 CG4006 gene product from transcript CG4006-RA 0.129
p24-1 p24-related-1 0.125
stumps CG31317 gene product from transcript CG31317-RC 0.124
pnr pannier 0.116
scny scrawny 0.113
Wnt2 Wnt oncogene analog 2 0.112
p53 CG33336 gene product from transcript CG33336-RB 0.112
Tsc1 CG6147 gene product from transcript CG6147-RA 0.097
p24-2 p24-related-2 0.093
wts warts 0.093
aop anterior open 0.091
pan pangolin 0.089
Trh Tryptophan hydroxylase 0.089
gish gilgamesh 0.087
fng fringe 0.085
CtBP C-terminal Binding Protein 0.082
Mi-2 CG8103 gene product from transcript CG8103-RA 0.081
rhea CG6831 gene product from transcript CG6831-RA 0.081
eya eyes absent 0.081
mnb minibrain 0.077
sd scalloped 0.075
mats mob as tumor suppressor 0.071
hipk homeodomain interacting protein kinase 0.070
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.069
capt capulet 0.069
egh egghead 0.066
ds dachsous 0.065
in inturned 0.064
B52 CG10851 gene product from transcript CG10851-RB 0.063
bnl branchless 0.061
lin lines 0.060
rok Rho-kinase 0.059
Tak1 TGF-beta activated kinase 1 0.059
Arp14D Actin-related protein 14D 0.058
nkd naked cuticle 0.055
stck steamer duck 0.055
pygo pygopus 0.054
sbb scribbler 0.052
nct nicastrin 0.050
tkv thickveins 0.050
dally division abnormally delayed 0.049
ssh slingshot 0.049
G-oalpha47A G protein oalpha 47A 0.049
Wnt4 Wnt oncogene analog 4 0.045
Rab11 Rab-protein 11 0.044
numb CG3779 gene product from transcript CG3779-RB 0.043
hbs hibris 0.043
twi twist 0.042
Ubx Ultrabithorax 0.040
Klp64D Kinesin-like protein at 64D 0.040
p38b CG7393 gene product from transcript CG7393-RA 0.040
caup caupolican 0.040
InR Insulin-like receptor 0.039
spz spatzle 0.039
shg shotgun 0.039
ft fat 0.039
l(2)gl lethal (2) giant larvae 0.037
nej nejire 0.036
hpo hippo 0.036
wb wing blister 0.036
ap apterous 0.035
Hs6st Heparan sulfate 6-O-sulfotransferase 0.035
dlp dally-like 0.034
bchs blue cheese 0.034
rst roughest 0.034
CG3371 CG3371 gene product from transcript CG3371-RA 0.034
Cortactin CG3637 gene product from transcript CG3637-RA 0.033
zfh1 Zn finger homeodomain 1 0.033
esg escargot 0.033
Cdc42 CG12530 gene product from transcript CG12530-RA 0.033
CG32372 CG32372 gene product from transcript CG32372-RA 0.031
Pkn Protein kinase related to protein kinase N 0.030
hkb huckebein 0.030
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.000
CSNK1E casein kinase 1, epsilon 0.999
SMAD3 SMAD family member 3 0.999
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.998
SMAD4 SMAD family member 4 0.998
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.998
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.996
SMAD7 SMAD family member 7 0.995
GSK3B glycogen synthase kinase 3 beta 0.993
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.990
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.985
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.979
SMAD2 SMAD family member 2 0.978
LRP6 low density lipoprotein receptor-related protein 6 0.974
FGFR1 fibroblast growth factor receptor 1 0.956
SUFU suppressor of fused homolog (Drosophila) 0.956
AXIN1 axin 1 0.951
GLIS2 GLIS family zinc finger 2 0.940
CCNY cyclin Y 0.935
ESR1 estrogen receptor 1 0.935
PSEN1 presenilin 1 0.931
CREBBP CREB binding protein 0.927
HIPK3 homeodomain interacting protein kinase 3 0.921
STRN3 striatin, calmodulin binding protein 3 0.920
AR androgen receptor 0.913
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.906
ZFYVE9 zinc finger, FYVE domain containing 9 0.892
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.883
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.883
APC adenomatous polyposis coli 0.877
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.873
JUP junction plakoglobin 0.872
ERBB2IP erbb2 interacting protein 0.870
TNIP2 TNFAIP3 interacting protein 2 0.864
DSP desmoplakin 0.863
HDAC1 histone deacetylase 1 0.855
BIRC2 baculoviral IAP repeat containing 2 0.842
EGFR epidermal growth factor receptor 0.829
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.825
SMAD1 SMAD family member 1 0.802
RNF11 ring finger protein 11 0.800
BTRC beta-transducin repeat containing 0.792
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.785
BMP7 bone morphogenetic protein 7 0.780
USP9X ubiquitin specific peptidase 9, X-linked 0.778
PPP6C protein phosphatase 6, catalytic subunit 0.770
YAP1 Yes-associated protein 1 0.766
TUBA1A tubulin, alpha 1a 0.757
CDK14 cyclin-dependent kinase 14 0.756
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.755
BMPR1A bone morphogenetic protein receptor, type IA 0.755
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.745
CDK6 cyclin-dependent kinase 6 0.741
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.739
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.738
GIPC1 GIPC PDZ domain containing family, member 1 0.734
ZNF512B zinc finger protein 512B 0.729
MARK3 MAP/microtubule affinity-regulating kinase 3 0.725
STK3 serine/threonine kinase 3 0.724
TBX5 T-box 5 0.722
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.719
CAV1 caveolin 1, caveolae protein, 22kDa 0.690
DSG2 desmoglein 2 0.688
STK4 serine/threonine kinase 4 0.671
POU3F2 POU class 3 homeobox 2 0.667
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.666
POU5F1 POU class 5 homeobox 1 0.656
CSNK1A1 casein kinase 1, alpha 1 0.652
UBE3A ubiquitin protein ligase E3A 0.645
AXIN2 axin 2 0.639
COL5A1 collagen, type V, alpha 1 0.636
PAX3 paired box 3 0.633
LRRK2 leucine-rich repeat kinase 2 0.616
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.601
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.582
FOXD3 forkhead box D3 0.573
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.562
BCL9 B-cell CLL/lymphoma 9 0.550
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.549
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.539
ARHGAP1 Rho GTPase activating protein 1 0.530
FGF1 fibroblast growth factor 1 (acidic) 0.527
FZD1 frizzled homolog 1 (Drosophila) 0.521
BTBD2 BTB (POZ) domain containing 2 0.519
SKP1 S-phase kinase-associated protein 1 0.518
SFRP1 secreted frizzled-related protein 1 0.512
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.510
BIRC3 baculoviral IAP repeat containing 3 0.509
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.497
FBXW11 F-box and WD repeat domain containing 11 0.488
AFF4 AF4/FMR2 family, member 4 0.487
DDR2 discoidin domain receptor tyrosine kinase 2 0.477
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.473
CHD8 chromodomain helicase DNA binding protein 8 0.470
SOX10 SRY (sex determining region Y)-box 10 0.468
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.467
CTNND1 catenin (cadherin-associated protein), delta 1 0.440
PTPRF protein tyrosine phosphatase, receptor type, F 0.434
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.432
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.424
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Rattus norvegicus
Name Description Probability Func Analog Organism
Btg2 BTG family, member 2 0.029
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.018
Hprt1 hypoxanthine phosphoribosyltransferase 1 0.016
Rala v-ral simian leukemia viral oncogene homolog A (ras related) 0.014
Golph3 golgi phosphoprotein 3 (coat-protein) 0.014
Taok1 TAO kinase 1 0.013
Fos FBJ osteosarcoma oncogene 0.012
Ier2 immediate early response 2 0.011
Rraga Ras-related GTP binding A 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism