The network for 'hair cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hair cycle

The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.

Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.999
Pten phosphatase and tensin homolog 0.995
Shh sonic hedgehog 0.985
Gli3 GLI-Kruppel family member GLI3 0.978
Col1a1 collagen, type I, alpha 1 0.971
Ctnnb1 catenin (cadherin associated protein), beta 1 0.971
Bmp4 bone morphogenetic protein 4 0.969
Fgfr1 fibroblast growth factor receptor 1 0.963
Vangl2 vang-like 2 (van gogh, Drosophila) 0.957
Vegfa vascular endothelial growth factor A 0.943
Notch2 Notch gene homolog 2 (Drosophila) 0.940
Foxc1 forkhead box C1 0.935
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.927
Hoxd13 homeobox D13 0.906
Fgf8 fibroblast growth factor 8 0.894
Apc adenomatosis polyposis coli 0.872
Bcl2 B-cell leukemia/lymphoma 2 0.871
Tgfb2 transforming growth factor, beta 2 0.866
Cav1 caveolin 1, caveolae protein 0.854
Csf1 colony stimulating factor 1 (macrophage) 0.848
Meox2 mesenchyme homeobox 2 0.847
Trp53 transformation related protein 53 0.820
Clock circadian locomotor output cycles kaput 0.811
Psen1 presenilin 1 0.811
Msx2 homeobox, msh-like 2 0.811
Smad4 MAD homolog 4 (Drosophila) 0.788
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.780
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.769
Wnt3a wingless-related MMTV integration site 3A 0.763
Foxa2 forkhead box A2 0.755
Bmp7 bone morphogenetic protein 7 0.746
Dlx3 distal-less homeobox 3 0.734
Tgfa transforming growth factor alpha 0.730
Krt35 keratin 35 0.725
Egfr epidermal growth factor receptor 0.718
Krt5 keratin 5 0.717
Per2 period homolog 2 (Drosophila) 0.702
Foxn1 forkhead box N1 0.698
Ptk7 PTK7 protein tyrosine kinase 7 0.695
Pax2 paired box gene 2 0.687
Lmx1b LIM homeobox transcription factor 1 beta 0.684
Igh immunoglobulin heavy chain complex 0.674
Pthlh parathyroid hormone-like peptide 0.674
Nos3 nitric oxide synthase 3, endothelial cell 0.672
Twist2 twist homolog 2 (Drosophila) 0.672
Krt17 keratin 17 0.668
Sox9 SRY-box containing gene 9 0.664
Krt14 keratin 14 0.658
Ret ret proto-oncogene 0.653
Hoxd11 homeobox D11 0.640
Eda ectodysplasin-A 0.639
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.638
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.630
Atoh7 atonal homolog 7 (Drosophila) 0.598
Bmpr1a bone morphogenetic protein receptor, type 1A 0.596
Gli2 GLI-Kruppel family member GLI2 0.586
Nog noggin 0.585
Krt33b keratin 33B 0.581
Npr3 natriuretic peptide receptor 3 0.579
Gata4 GATA binding protein 4 0.575
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.564
Kl klotho 0.560
Gli1 GLI-Kruppel family member GLI1 0.536
Cry2 cryptochrome 2 (photolyase-like) 0.535
Clcnka chloride channel Ka 0.531
Pkp1 plakophilin 1 0.524
Pax3 paired box gene 3 0.518
Hr hairless 0.516
Sox7 SRY-box containing gene 7 0.497
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.488
Edar ectodysplasin-A receptor 0.487
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.482
Pou3f3 POU domain, class 3, transcription factor 3 0.475
Emx2 empty spiracles homolog 2 (Drosophila) 0.473
Otx2 orthodenticle homolog 2 (Drosophila) 0.470
Wnt4 wingless-related MMTV integration site 4 0.466
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.463
Nkx2-1 NK2 homeobox 1 0.455
Hif1a hypoxia inducible factor 1, alpha subunit 0.452
Tbx15 T-box 15 0.451
Msx1 homeobox, msh-like 1 0.448
Gbx2 gastrulation brain homeobox 2 0.446
Runx2 runt related transcription factor 2 0.443
Nos2 nitric oxide synthase 2, inducible 0.440
Alx4 aristaless-like homeobox 4 0.431
Lgals7 lectin, galactose binding, soluble 7 0.425
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.424
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.411
Rxra retinoid X receptor alpha 0.411
Acvr1 activin A receptor, type 1 0.409
Socs1 suppressor of cytokine signaling 1 0.405
Tbx1 T-box 1 0.405
Ptch2 patched homolog 2 0.397
Tbx2 T-box 2 0.397
Gsk3b glycogen synthase kinase 3 beta 0.396
Fzd1 frizzled homolog 1 (Drosophila) 0.393
Krt86 keratin 86 0.391
Lama5 laminin, alpha 5 0.387
Krt36 keratin 36 0.384
Padi3 peptidyl arginine deiminase, type III 0.381
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
KRT6B keratin 6B 1.000
KRT15 keratin 15 0.996
KRT17 keratin 17 0.993
KRT5 keratin 5 0.992
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) 0.987
KRT8 keratin 8 0.982
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.966
KRT34 keratin 34 0.949
KRT18 keratin 18 0.948
KRT6A keratin 6A 0.928
KRT14 keratin 14 0.919
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.901
MPZL2 myelin protein zero-like 2 0.834
TP63 tumor protein p63 0.825
PSEN1 presenilin 1 0.823
TRIM29 tripartite motif containing 29 0.804
LMO4 LIM domain only 4 0.792
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.781
KRT33B keratin 33B 0.781
KRT19 keratin 19 0.777
KRT6C keratin 6C 0.746
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.714
TGFB1 transforming growth factor, beta 1 0.698
HDAC2 histone deacetylase 2 0.688
ARRB1 arrestin, beta 1 0.679
BCL2L1 BCL2-like 1 0.656
NOTCH1 notch 1 0.605
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.572
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.522
KRT32 keratin 32 0.513
FGF1 fibroblast growth factor 1 (acidic) 0.494
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.478
FST follistatin 0.470
FKBP1A FK506 binding protein 1A, 12kDa 0.467
KLK10 kallikrein-related peptidase 10 0.452
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.438
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.411
STK3 serine/threonine kinase 3 0.393
KRT81 keratin 81 0.390
TP53 tumor protein p53 0.389
AHR aryl hydrocarbon receptor 0.357
KRT16 keratin 16 0.337
TNRC6A trinucleotide repeat containing 6A 0.330
HDAC1 histone deacetylase 1 0.329
FSTL1 follistatin-like 1 0.327
ITGB4 integrin, beta 4 0.306
KRT38 keratin 38 0.305
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.302
PPL periplakin 0.301
KRT75 keratin 75 0.300
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.299
JAG1 jagged 1 0.296
PDZD11 PDZ domain containing 11 0.294
SPRR1A small proline-rich protein 1A 0.273
LY6D lymphocyte antigen 6 complex, locus D 0.260
DSG2 desmoglein 2 0.252
KRT33A keratin 33A 0.238
CTNND1 catenin (cadherin-associated protein), delta 1 0.233
FGF10 fibroblast growth factor 10 0.232
NOTCH3 notch 3 0.229
C19orf50 chromosome 19 open reading frame 50 0.224
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.218
FGFR3 fibroblast growth factor receptor 3 0.213
KRT31 keratin 31 0.212
INHBA inhibin, beta A 0.204
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.202
POU3F2 POU class 3 homeobox 2 0.192
KRT4 keratin 4 0.191
GJB3 gap junction protein, beta 3, 31kDa 0.191
KRT1 keratin 1 0.185
NCOR2 nuclear receptor corepressor 2 0.180
IVL involucrin 0.180
DSG3 desmoglein 3 0.177
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.171
EPAS1 endothelial PAS domain protein 1 0.170
RB1 retinoblastoma 1 0.168
GSK3B glycogen synthase kinase 3 beta 0.164
BMP2 bone morphogenetic protein 2 0.162
LYPD3 LY6/PLAUR domain containing 3 0.157
KRT9 keratin 9 0.155
NUCB1 nucleobindin 1 0.154
KRT35 keratin 35 0.151
MSX1 msh homeobox 1 0.147
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.143
RLIM ring finger protein, LIM domain interacting 0.142
SALL2 sal-like 2 (Drosophila) 0.136
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.132
SPEN spen homolog, transcriptional regulator (Drosophila) 0.128
TACSTD2 tumor-associated calcium signal transducer 2 0.127
KRT36 keratin 36 0.125
LRP6 low density lipoprotein receptor-related protein 6 0.125
SPRR1B small proline-rich protein 1B 0.121
FOXD3 forkhead box D3 0.119
NCOA2 nuclear receptor coactivator 2 0.119
JAG2 jagged 2 0.115
KRT13 keratin 13 0.110
TEKT4 tektin 4 0.103
BMP7 bone morphogenetic protein 7 0.103
FGF18 fibroblast growth factor 18 0.103
JUP junction plakoglobin 0.102
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Rattus norvegicus
Name Description Probability Func Analog Organism
Itpr3 inositol 1,4,5-triphosphate receptor, type 3 0.054
Rabac1 Rab acceptor 1 (prenylated) 0.038
Unc5b unc-5 homolog B (C. elegans) 0.034
Muc1 mucin 1, cell surface associated 0.034
Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.033
Foxn1 forkhead box N1 0.032
Dll3 delta-like 3 (Drosophila) 0.029
Pebp1 phosphatidylethanolamine binding protein 1 0.029
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.027
Tgfb2 transforming growth factor, beta 2 0.027
Teddm1 transmembrane epididymal protein 1 0.026
Sprr1al small proline-rich protein 1A-like 0.026
Cldn3 claudin 3 0.023
Igfbp5 insulin-like growth factor binding protein 5 0.023
Fosl1 fos-like antigen 1 0.023
Sox7 SRY (sex determining region Y)-box 7 0.022
Dchs1 dachsous 1 (Drosophila) 0.022
Slit3 slit homolog 3 (Drosophila) 0.022
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.021
Olr837 olfactory receptor 837 0.021
Cstb cystatin B (stefin B) 0.021
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.021
Edn1 endothelin 1 0.021
Cox8a cytochrome c oxidase subunit VIIIa 0.021
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.020
Prph2 peripherin 2 0.020
Kcnk1 potassium channel, subfamily K, member 1 0.020
Smad7 SMAD family member 7 0.020
Megf6 multiple EGF-like-domains 6 0.020
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.019
Vcan versican 0.019
Il6 interleukin 6 0.019
Nradd neurotrophin receptor associated death domain 0.019
Krt15 keratin 15 0.019
Thbd thrombomodulin 0.018
Spt1 salivary protein 1 0.018
Pspn persephin 0.018
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.018
Lepr leptin receptor 0.018
Olr37 olfactory receptor 37 0.018
Ednrb endothelin receptor type B 0.018
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.018
Pgf placental growth factor 0.018
Gpx4 glutathione peroxidase 4 0.018
Gstp1 glutathione S-transferase pi 1 0.017
Gja5 gap junction protein, alpha 5 0.017
Ddt D-dopachrome tautomerase 0.017
Sox2 SRY (sex determining region Y)-box 2 0.017
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.017
Dnajb14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.017
Foxa3 forkhead box A3 0.017
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.017
Cdon Cdon homolog (mouse) 0.017
Ier5 immediate early response 5 0.016
Twist2 twist homolog 2 (Drosophila) 0.016
Slc16a3 solute carrier family 16, member 3 (monocarboxylic acid transporter 4) 0.016
Acy1 aminoacylase 1 0.016
Wnt5b wingless-type MMTV integration site family, member 5B 0.016
Ren renin 0.016
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.016
Ednra endothelin receptor type A 0.016
Pcdhga11 protocadherin gamma subfamily A, 11 0.016
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.016
Gem GTP binding protein (gene overexpressed in skeletal muscle) 0.016
Dlgap2 discs, large (Drosophila) homolog-associated protein 2 0.016
Kdr kinase insert domain receptor 0.016
RT1-DOa RT1 class II, locus DOa 0.015
Col8a1 collagen, type VIII, alpha 1 0.015
Tmem205 transmembrane protein 205 0.015
Hr hairless 0.015
L3mbtl3 l(3)mbt-like 3 (Drosophila) 0.015
RGD1563060 similar to AVLV472 0.015
A4galt alpha 1,4-galactosyltransferase 0.015
Kl Klotho 0.015
Egfr epidermal growth factor receptor 0.015
Arid1a AT rich interactive domain 1A (SWI-like) 0.015
Fbln2 fibulin 2 0.015
Cdh4 cadherin 4 0.015
Chrnb4 cholinergic receptor, nicotinic, beta 4 0.015
Ptms parathymosin 0.015
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.015
Olr737 olfactory receptor 737 0.015
Cdh16 cadherin 16 0.015
Grb10 growth factor receptor bound protein 10 0.015
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.015
Gpr115 G protein-coupled receptor 115 0.015
Bsg basigin 0.015
Tgfb3 transforming growth factor, beta 3 0.015
LOC679931 hypothetical protein LOC679931 0.015
Rtn4r reticulon 4 receptor 0.015
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.014
C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 0.014
Csf3 colony stimulating factor 3 (granulocyte) 0.014
Capn6 calpain 6 0.014
Ddrgk1 DDRGK domain containing 1 0.014
Olfml2a olfactomedin-like 2A 0.014
Plaur plasminogen activator, urokinase receptor 0.014
Foxq1 forkhead box Q1 0.014
Prrx1 paired related homeobox 1 0.014
Gtf2i general transcription factor II I 0.014
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism