The network for 'oocyte axis specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

oocyte axis specification

The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.

Mus musculus
Name Description Probability Func Analog Organism
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1.000
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 1.000
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Apc adenomatosis polyposis coli 0.999
Fgfr2 fibroblast growth factor receptor 2 0.994
Shh sonic hedgehog 0.991
Smad4 MAD homolog 4 (Drosophila) 0.988
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.987
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.986
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.983
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.969
Stx1a syntaxin 1A (brain) 0.969
Sox9 SRY-box containing gene 9 0.966
Nf1 neurofibromatosis 1 0.954
Htt huntingtin 0.949
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.936
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.923
Set SET nuclear oncogene 0.907
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.906
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.891
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.889
Fus fusion, derived from t(12;16) malignant liposarcoma (human) 0.887
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.883
Tgfb2 transforming growth factor, beta 2 0.878
Lrrk2 leucine-rich repeat kinase 2 0.864
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.862
Hif1a hypoxia inducible factor 1, alpha subunit 0.862
Foxc1 forkhead box C1 0.858
Rpgrip1l Rpgrip1-like 0.857
Ptch1 patched homolog 1 0.855
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.846
Bmpr1a bone morphogenetic protein receptor, type 1A 0.839
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.807
Dlg1 discs, large homolog 1 (Drosophila) 0.805
Hspa8 heat shock protein 8 0.799
Ncl nucleolin 0.788
Gli3 GLI-Kruppel family member GLI3 0.783
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.763
Fgfr3 fibroblast growth factor receptor 3 0.757
Pten phosphatase and tensin homolog 0.741
Snap25 synaptosomal-associated protein 25 0.732
Vasp vasodilator-stimulated phosphoprotein 0.731
Prrx1 paired related homeobox 1 0.716
Smad1 MAD homolog 1 (Drosophila) 0.710
1110004F10Rik RIKEN cDNA 1110004F10 gene 0.707
Acvr1 activin A receptor, type 1 0.705
Tsc2 tuberous sclerosis 2 0.685
Ret ret proto-oncogene 0.674
Dlg4 discs, large homolog 4 (Drosophila) 0.658
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.645
Kdm1a lysine (K)-specific demethylase 1A 0.645
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.638
Gja1 gap junction protein, alpha 1 0.629
Gli2 GLI-Kruppel family member GLI2 0.627
Raf1 v-raf-leukemia viral oncogene 1 0.627
Vamp2 vesicle-associated membrane protein 2 0.606
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.588
Cct2 chaperonin containing Tcp1, subunit 2 (beta) 0.574
Tsc1 tuberous sclerosis 1 0.563
Raver2 ribonucleoprotein, PTB-binding 2 0.556
Smo smoothened homolog (Drosophila) 0.550
Fgfr1 fibroblast growth factor receptor 1 0.545
Cltc clathrin, heavy polypeptide (Hc) 0.534
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.532
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.523
Bmp4 bone morphogenetic protein 4 0.517
Mtpn myotrophin 0.514
Bdnf brain derived neurotrophic factor 0.511
Chrd chordin 0.508
Lmna lamin A 0.503
Gsk3b glycogen synthase kinase 3 beta 0.502
Nrg1 neuregulin 1 0.489
Phox2a paired-like homeobox 2a 0.487
Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform 0.482
Nudc nuclear distribution gene C homolog (Aspergillus) 0.481
Ap2a1 adaptor protein complex AP-2, alpha 1 subunit 0.480
Fgf8 fibroblast growth factor 8 0.476
Col1a1 collagen, type I, alpha 1 0.460
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.458
Tcfap2a transcription factor AP-2, alpha 0.447
Spnb2 spectrin beta 2 0.445
Bmp7 bone morphogenetic protein 7 0.444
Trp53 transformation related protein 53 0.440
Caprin1 cell cycle associated protein 1 0.439
Src Rous sarcoma oncogene 0.433
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.432
Braf Braf transforming gene 0.431
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.431
Arid1b AT rich interactive domain 1B (SWI-like) 0.425
Smad2 MAD homolog 2 (Drosophila) 0.420
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.418
Ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.416
Hnrnpu heterogeneous nuclear ribonucleoprotein U 0.415
Ube2n ubiquitin-conjugating enzyme E2N 0.409
Gna13 guanine nucleotide binding protein, alpha 13 0.406
Csnk2a1 casein kinase 2, alpha 1 polypeptide 0.405
Rb1 retinoblastoma 1 0.399
Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein 0.394
Prkce protein kinase C, epsilon 0.391
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
par-5 Protein PAR-5 0.776
rpl-7 Protein RPL-7 0.706
spk-1 Protein SPK-1 0.611
Y65B4BR.5 Protein Y65B4BR.5 0.523
tba-2 Protein TBA-2 0.459
mcm-2 Protein MCM-2 0.415
icd-1 Protein ICD-1 0.396
glh-1 Protein GLH-1 0.377
rpl-6 Protein RPL-6 0.372
lmn-1 Protein LMN-1 0.363
rpl-4 Protein RPL-4 0.354
tag-153 Protein TAG-153 0.352
rars-1 Protein RARS-1 0.334
tbb-2 Protein TBB-2 0.313
snr-4 Protein SNR-4 0.311
F58E10.3 Protein F58E10.3 0.308
ucr-2.3 Protein UCR-2.3 0.308
CELE_C01G10.8 Protein C01G10.8 0.302
mpk-1 Protein MPK-1 0.291
F56D2.6 Protein F56D2.6 0.287
par-2 Protein PAR-2 0.287
imb-3 Protein IMB-3 0.280
goa-1 Protein GOA-1 0.272
ahcy-1 Protein AHCY-1 0.269
kin-3 Protein KIN-3 0.266
rpl-25.2 Protein RPL-25.2 0.259
glh-4 Protein GLH-4 0.256
tbb-1 Protein TBB-1 0.225
pgl-1 Protein PGL-1 0.222
rpl-12 Protein RPL-12 0.219
rpl-13 Protein RPL-13 0.208
xpo-2 Protein XPO-2 0.205
rpl-3 Protein RPL-3 0.204
retr-1 Protein RETR-1 0.194
wrm-1 Protein WRM-1 0.193
CELE_C17H12.13 Protein C17H12.13 0.193
cgh-1 Protein CGH-1 0.191
tct-1 Protein TCT-1 0.190
cls-2 Protein CLS-2 0.190
hsr-9 Protein HSR-9 0.185
rpl-19 Protein RPL-19 0.183
rps-6 Protein RPS-6 0.181
tac-1 Protein TAC-1 0.180
ZK686.3 Protein ZK686.3 0.179
csnk-1 Protein CSNK-1 0.174
gpb-1 Protein GPB-1 0.172
eftu-2 Protein EFTU-2 0.171
klp-15 Protein KLP-15 0.171
rla-0 Protein RLA-0 0.167
rps-7 Protein RPS-7 0.166
cdc-48.1 Protein CDC-48.1 0.160
eef-1A.1 Protein EEF-1A.1 0.159
rpa-2 Protein RPA-2 0.159
arf-3 Protein ARF-3 0.158
acs-4 Protein ACS-4 0.155
rps-2 Protein RPS-2 0.149
CELE_K08F4.2 Protein K08F4.2 0.149
cey-1 Protein CEY-1 0.149
gdi-1 Protein GDI-1 0.148
cct-1 Protein CCT-1 0.146
pas-3 Protein PAS-3 0.146
xpo-1 Protein XPO-1 0.145
rpl-2 Protein RPL-2 0.143
cst-2 Protein CST-2 0.142
rod-1 Protein ROD-1 0.142
rpl-11.1 Protein RPL-11.1 0.141
mat-3 Protein MAT-3 0.137
rps-3 Protein RPS-3 0.134
wago-1 Protein WAGO-1 0.129
F54D12.4 Protein F54D12.4 0.125
C27H6.8 Protein C27H6.8 0.123
rpn-6.1 Protein RPN-6.1 0.122
rpl-15 Protein RPL-15 0.120
npp-13 Protein NPP-13 0.118
lin-45 Protein LIN-45 0.117
pqn-87 Protein PQN-87 0.116
ina-1 Protein INA-1 0.114
imb-1 Protein IMB-1 0.114
got-2.1 Protein GOT-2.1 0.112
his-6 Protein HIS-6 0.112
rpt-5 Protein RPT-5 0.111
rpl-24.1 Protein RPL-24.1 0.111
hpo-40 Protein HPO-40 0.111
imb-2 Protein IMB-2 0.110
crt-1 Protein CRT-1 0.110
snr-2 Protein SNR-2 0.109
unc-43 Protein UNC-43 0.109
unc-16 Protein UNC-16 0.106
rpl-30 Protein RPL-30 0.105
mre-11 Protein MRE-11 0.105
npp-7 Protein NPP-7 0.104
prg-1 Protein PRG-1 0.103
rps-26 Protein RPS-26 0.101
mog-2 Protein MOG-2 0.100
tba-1 Protein TBA-1 0.099
W08E12.7 Protein W08E12.7 0.098
pbs-6 Protein PBS-6 0.098
dpy-30 Protein DPY-30 0.096
CELE_C16C10.4 Protein C16C10.4 0.096
let-60 Protein LET-60 0.095
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Danio rerio
Name Description Probability Func Analog Organism
piwil1 piwi-like 1 (Drosophila) 0.857
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.840
nanos3 nanos homolog 3 0.824
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.787
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.597
org oogenesis-related gene 0.418
brca2 breast cancer 2, early onset 0.411
foxh1 forkhead box H1 0.394
ca15b carbonic anhydrase XV b 0.350
spsb1 splA/ryanodine receptor domain and SOCS box containing 1 0.286
dazl daz-like gene 0.283
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.281
bmp4 bone morphogenetic protein 4 0.232
fancl Fanconi anemia, complementation group L 0.219
e2f5 E2F transcription factor 5 0.209
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.197
znf711 zinc finger protein 711 0.184
pfn2 profilin 2 0.162
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.161
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.160
tdrd1 tudor domain containing 1 0.127
piwil2 piwi-like 2 (Drosophila) 0.122
si:ch1073-351m12.1 si:ch1073-351m12.1 0.120
srsf2 serine/arginine-rich splicing factor 2 0.113
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.113
snx6 sorting nexin 6 0.112
bmp2b bone morphogenetic protein 2b 0.112
rap1b RAS related protein 1b 0.112
buc bucky ball 0.107
tubg1 tubulin, gamma 1 0.086
dlg2 discs, large (Drosophila) homolog 2 0.075
flot1b flotillin 1b 0.074
sfrs3b splicing factor, arginine/serine-rich 3b 0.071
zorba Orb/CPEB-related RNA-binding protein 0.070
gdf9 growth differentiation factor 9 0.068
hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 0.068
c20orf14 c20orf14 homolog (H. sapiens) 0.068
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.067
pou5f1 POU domain, class 5, transcription factor 1 0.067
psen1 presenilin 1 0.065
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.062
tbpl2 TATA box binding protein like 2 0.059
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.057
elavl2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) 0.049
smu1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0.047
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.047
fzd2 frizzled homolog 2 0.047
acvr1l activin A receptor, type I like 0.044
ubin ataxin-1 ubiquitin-like interacting protein 0.043
lamc1 laminin, gamma 1 0.042
actn1 actinin, alpha 1 0.041
hmga1a high mobility group AT-hook 1a 0.041
celf1 cugbp, Elav-like family member 1 0.040
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.040
tbx16 T-box gene 16 0.039
sybu syntabulin (syntaxin-interacting) 0.039
uba1 ubiquitin-like modifier activating enzyme 1 0.038
szl sizzled 0.038
ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.038
strap serine/threonine kinase receptor associated protein 0.035
laptm4a lysosomal-associated protein transmembrane 4 alpha 0.034
cltcb clathrin, heavy polypeptide b (Hc) 0.033
esyt3 extended synaptotagmin-like protein 3 0.031
ck2b casein kinase 2 beta 0.031
extl3 exostoses (multiple)-like 3 0.031
ilf3b interleukin enhancer binding factor 3b 0.030
prpf40a PRP40 pre-mRNA processing factor 40 homolog A (yeast) 0.030
gap43 growth associated protein 43 0.030
ntla no tail a 0.030
hnrnpa0l heterogeneous nuclear ribonucleoprotein A0, like 0.030
smad5 MAD homolog 5 (Drosophila) 0.029
eif3c eukaryotic translation initiation factor 3, subunit C 0.029
prmt1 protein arginine methyltransferase 1 0.029
lims1 LIM and senescent cell antigen-like domains 1 0.028
zgc:77155 zgc:77155 0.028
rbm4.3 RNA binding motif protein 4.3 0.027
zgc:193933 zgc:193933 0.027
zgc:112425 zgc:112425 0.026
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.025
pob partial optokinetic response b 0.025
frem1a Fras1 related extracellular matrix 1a 0.025
calm1a calmodulin 1a 0.024
srsf6a serine/arginine-rich splicing factor 6a 0.024
bactin1 bactin1 0.024
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.023
ilk integrin linked kinase 0.023
arpc5a actin related protein 2/3 complex, subunit 5A 0.023
usp10 ubiquitin specific peptidase 10 0.023
pl10 pl10 0.023
jup junction plakoglobin 0.022
tubb2c tubulin, beta 2c 0.022
sox32 SRY-box containing gene 32 0.022
arf2 ADP-ribosylation factor 2 0.021
vps35 vacuolar protein sorting 35 (yeast) 0.021
pak2a p21 (CDKN1A)-activated kinase 2a 0.021
hnrnpu heterogeneous nuclear ribonucleoprotein U 0.021
ube2na ubiquitin-conjugating enzyme E2Na 0.020
hk1 hexokinase 1 0.020
uxs1 UDP-glucuronic acid decarboxylase 1 0.020
eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 0.020
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Drosophila melanogaster
Name Description Probability Func Analog Organism
sqd squid 1.000
baz bazooka 1.000
BicD Bicaudal D 1.000
mael maelstrom 1.000
stau staufen 0.999
tsu tsunagi 0.999
slmb supernumerary limbs 0.999
Cdc42 CG12530 gene product from transcript CG12530-RA 0.999
Lam Lamin 0.998
Src64B Src oncogene at 64B 0.997
par-6 CG5884 gene product from transcript CG5884-RA 0.997
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.996
aret arrest 0.996
tral trailer hitch 0.996
pum pumilio 0.995
me31B maternal expression at 31B 0.993
par-1 CG8201 gene product from transcript CG8201-RA 0.993
pita CG3941 gene product from transcript CG3941-RA 0.993
psq pipsqueak 0.991
Dhc64C Dynein heavy chain 64C 0.989
JIL-1 CG6297 gene product from transcript CG6297-RA 0.987
arm armadillo 0.987
grk gurken 0.986
cup CG11181 gene product from transcript CG11181-RB 0.985
Hel25E Helicase at 25E 0.985
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.984
mago mago nashi 0.983
Khc Kinesin heavy chain 0.980
sax saxophone 0.978
CG11188 CG11188 gene product from transcript CG11188-RA 0.978
Dlic Dynein light intermediate chain 0.977
SRPK CG8174 gene product from transcript CG8174-RA 0.977
osk oskar 0.977
Lis-1 Lissencephaly-1 0.974
Rab11 Rab-protein 11 0.972
aPKC atypical protein kinase C 0.972
hts hu li tai shao 0.969
tho2 CG31671 gene product from transcript CG31671-RA 0.967
CG6854 CG6854 gene product from transcript CG6854-RC 0.958
rok Rho-kinase 0.957
sec5 CG8843 gene product from transcript CG8843-RA 0.946
spn-E spindle E 0.943
cact cactus 0.938
sqh spaghetti squash 0.934
vas vasa 0.934
glo glorund 0.932
spir spire 0.930
TER94 CG2331 gene product from transcript CG2331-RA 0.930
cpa capping protein alpha 0.925
bel belle 0.919
ttk tramtrack 0.916
egh egghead 0.915
Eip75B Ecdysone-induced protein 75B 0.899
Atx2 Ataxin-2 0.875
del deadlock 0.870
Rab5 Rab-protein 5 0.869
spn-F CG12114 gene product from transcript CG12114-RA 0.857
yu CG3249 gene product from transcript CG3249-RA 0.843
usp ultraspiracle 0.840
Rac1 CG2248 gene product from transcript CG2248-RA 0.833
tkv thickveins 0.832
orb oo18 RNA-binding protein 0.829
vls valois 0.813
Gprk2 G protein-coupled receptor kinase 2 0.811
stai stathmin 0.811
mtrm matrimony 0.809
Fmr1 CG6203 gene product from transcript CG6203-RC 0.806
Tl Toll 0.792
zip zipper 0.788
shg shotgun 0.770
egg eggless 0.766
fs(1)K10 female sterile (1) K10 0.733
spen split ends 0.730
Pen Pendulin 0.721
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.712
Rab6 Rab-protein 6 0.709
tud tudor 0.693
Mi-2 CG8103 gene product from transcript CG8103-RA 0.692
Dmn Dynamitin 0.674
capu cappuccino 0.673
Chc Clathrin heavy chain 0.666
msn misshapen 0.665
lsn larsen 0.649
enc encore 0.641
Dcp1 Decapping protein 1 0.636
Moe Moesin 0.628
CSN5 COP9 complex homolog subunit 5 0.627
Sop2 Suppressor of profilin 2 0.624
smt3 CG4494 gene product from transcript CG4494-RA 0.621
cnn centrosomin 0.617
fu fused 0.599
CycG Cyclin G 0.587
Fas2 Fasciclin 2 0.571
Letm1 CG4589 gene product from transcript CG4589-RB 0.559
spi spitz 0.558
kel kelch 0.554
l(2)gl lethal (2) giant larvae 0.554
CG17838 CG17838 gene product from transcript CG17838-RA 0.547
gus gustavus 0.538
RpL10Ab Ribosomal protein L10Ab 0.537
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism