IMP
Process View
The network for 'receptor biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
receptor biosynthetic process
The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pten | phosphatase and tensin homolog | 0.827 | |
| Apoe | apolipoprotein E | 0.719 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.534 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.511 | |
| Cav1 | caveolin 1, caveolae protein | 0.459 | |
| Trp53 | transformation related protein 53 | 0.390 | |
| Rbbp7 | retinoblastoma binding protein 7 | 0.353 | |
| Lepr | leptin receptor | 0.325 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.322 | |
| Ghr | growth hormone receptor | 0.311 | |
| Hdac1 | histone deacetylase 1 | 0.286 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.273 | |
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.246 | |
| Rxra | retinoid X receptor alpha | 0.228 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.199 | |
| Hnrnpa2b1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.198 | |
| Hnrnph1 | heterogeneous nuclear ribonucleoprotein H1 | 0.173 | |
| Morf4l2 | mortality factor 4 like 2 | 0.165 | |
| Lep | leptin | 0.160 | |
| Ddx5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 0.157 | |
| Cidec | cell death-inducing DFFA-like effector c | 0.147 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.143 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.141 | |
| Mta2 | metastasis-associated gene family, member 2 | 0.135 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.134 | |
| Hnrnph2 | heterogeneous nuclear ribonucleoprotein H2 | 0.132 | |
| Egfr | epidermal growth factor receptor | 0.127 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.125 | |
| Foxa2 | forkhead box A2 | 0.117 | |
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.108 | |
| Rad21 | RAD21 homolog (S. pombe) | 0.094 | |
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.092 | |
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.090 | |
| Hdac2 | histone deacetylase 2 | 0.084 | |
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.084 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.084 | |
| Ar | androgen receptor | 0.079 | |
| Vegfa | vascular endothelial growth factor A | 0.070 | |
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.067 | |
| Sox2 | SRY-box containing gene 2 | 0.067 | |
| Il6st | interleukin 6 signal transducer | 0.064 | |
| Hnrnpd | heterogeneous nuclear ribonucleoprotein D | 0.064 | |
| Ppara | peroxisome proliferator activated receptor alpha | 0.061 | |
| Hoxb5 | homeobox B5 | 0.061 | |
| Matr3 | matrin 3 | 0.059 | |
| Zfp932 | zinc finger protein 932 | 0.058 | |
| Bmp4 | bone morphogenetic protein 4 | 0.058 | |
| Hnrnpr | heterogeneous nuclear ribonucleoprotein R | 0.055 | |
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.055 | |
| Cyld | cylindromatosis (turban tumor syndrome) | 0.053 | |
| Psen1 | presenilin 1 | 0.053 | |
| Gja1 | gap junction protein, alpha 1 | 0.052 | |
| Gnrh1 | gonadotropin releasing hormone 1 | 0.051 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.051 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.049 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.048 | |
| Rb1 | retinoblastoma 1 | 0.047 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.047 | |
| Epas1 | endothelial PAS domain protein 1 | 0.047 | |
| Sntb1 | syntrophin, basic 1 | 0.047 | |
| Npc1 | Niemann Pick type C1 | 0.047 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.047 | |
| Csnk1a1 | casein kinase 1, alpha 1 | 0.046 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.045 | |
| Gsta3 | glutathione S-transferase, alpha 3 | 0.044 | |
| Ldlr | low density lipoprotein receptor | 0.043 | |
| Tuba1a | tubulin, alpha 1A | 0.042 | |
| Ywhae | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.042 | |
| Col1a1 | collagen, type I, alpha 1 | 0.041 | |
| Agpat2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 0.041 | |
| Adig | adipogenin | 0.041 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.041 | |
| Adrb1 | adrenergic receptor, beta 1 | 0.040 | |
| Fabp1 | fatty acid binding protein 1, liver | 0.039 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.039 | |
| Braf | Braf transforming gene | 0.037 | |
| Meox2 | mesenchyme homeobox 2 | 0.037 | |
| Ptrf | polymerase I and transcript release factor | 0.036 | |
| Prlr | prolactin receptor | 0.035 | |
| Ces1f | carboxylesterase 1F | 0.035 | |
| Pon1 | paraoxonase 1 | 0.034 | |
| Sp3 | trans-acting transcription factor 3 | 0.033 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.033 | |
| Ywhaq | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.033 | |
| Kitl | kit ligand | 0.032 | |
| Thrsp | thyroid hormone responsive SPOT14 homolog (Rattus) | 0.032 | |
| Sumo1 | SMT3 suppressor of mif two 3 homolog 1 (yeast) | 0.032 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.031 | |
| Cftr | cystic fibrosis transmembrane conductance regulator homolog | 0.031 | |
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.031 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.030 | |
| Spp1 | secreted phosphoprotein 1 | 0.030 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.030 | |
| Eif4g2 | eukaryotic translation initiation factor 4, gamma 2 | 0.030 | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.030 | |
| Ccnd1 | cyclin D1 | 0.029 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.029 | |
| Wsb1 | WD repeat and SOCS box-containing 1 | 0.029 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.029 | |
| Ahr | aryl-hydrocarbon receptor | 0.029 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.989 | |
| HDAC1 | histone deacetylase 1 | 0.893 | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.759 | |
| HOXB5 | homeobox B5 | 0.601 | |
| RXRA | retinoid X receptor, alpha | 0.544 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.328 | |
| ESR1 | estrogen receptor 1 | 0.322 | |
| ENG | endoglin | 0.285 | |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.264 | |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.263 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.261 | |
| FHL2 | four and a half LIM domains 2 | 0.245 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.243 | |
| MED25 | mediator complex subunit 25 | 0.242 | |
| TLN1 | talin 1 | 0.227 | |
| IL22RA1 | interleukin 22 receptor, alpha 1 | 0.202 | |
| FN1 | fibronectin 1 | 0.184 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.165 | |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 0.127 | |
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.127 | |
| HDAC3 | histone deacetylase 3 | 0.125 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.114 | |
| PXN | paxillin | 0.103 | |
| HOXB3 | homeobox B3 | 0.099 | |
| HOXB6 | homeobox B6 | 0.094 | |
| HOXB7 | homeobox B7 | 0.089 | |
| HOXA10 | homeobox A10 | 0.088 | |
| IL10RA | interleukin 10 receptor, alpha | 0.086 | |
| EP300 | E1A binding protein p300 | 0.083 | |
| HOXA5 | homeobox A5 | 0.079 | |
| RARA | retinoic acid receptor, alpha | 0.068 | |
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.067 | |
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.061 | |
| VHL | von Hippel-Lindau tumor suppressor | 0.059 | |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 | 0.059 | |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.058 | |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.058 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.055 | |
| HOXB9 | homeobox B9 | 0.049 | |
| SIRT1 | sirtuin 1 | 0.049 | |
| IL22RA2 | interleukin 22 receptor, alpha 2 | 0.048 | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.048 | |
| HOXA6 | homeobox A6 | 0.048 | |
| THBS1 | thrombospondin 1 | 0.046 | |
| ITGB4 | integrin, beta 4 | 0.046 | |
| EDF1 | endothelial differentiation-related factor 1 | 0.043 | |
| HOXC10 | homeobox C10 | 0.042 | |
| HOXA4 | homeobox A4 | 0.042 | |
| HOXA7 | homeobox A7 | 0.042 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.041 | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.037 | |
| HR | hairless homolog (mouse) | 0.035 | |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.035 | |
| ESRRG | estrogen-related receptor gamma | 0.032 | |
| CD9 | CD9 molecule | 0.031 | |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.030 | |
| HMGA1 | high mobility group AT-hook 1 | 0.030 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.028 | |
| KRT15 | keratin 15 | 0.028 | |
| NCOA6 | nuclear receptor coactivator 6 | 0.026 | |
| TRADD | TNFRSF1A-associated via death domain | 0.026 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.024 | |
| SMAD5 | SMAD family member 5 | 0.023 | |
| FLNA | filamin A, alpha | 0.022 | |
| MTA3 | metastasis associated 1 family, member 3 | 0.022 | |
| ITGB5 | integrin, beta 5 | 0.022 | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.020 | |
| HOXA2 | homeobox A2 | 0.019 | |
| RXRG | retinoid X receptor, gamma | 0.019 | |
| HOXC6 | homeobox C6 | 0.018 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.018 | |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.018 | |
| HOXA3 | homeobox A3 | 0.018 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.018 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.017 | |
| HOXB4 | homeobox B4 | 0.017 | |
| HOXA1 | homeobox A1 | 0.017 | |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.016 | |
| HOXB2 | homeobox B2 | 0.015 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.015 | |
| HOXC9 | homeobox C9 | 0.014 | |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | 0.014 | |
| HOXC5 | homeobox C5 | 0.014 | |
| MSTO1 | misato homolog 1 (Drosophila) | 0.013 | |
| RARG | retinoic acid receptor, gamma | 0.013 | |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 | 0.013 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.013 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.013 | |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.013 | |
| MARCO | macrophage receptor with collagenous structure | 0.012 | |
| ITGA7 | integrin, alpha 7 | 0.012 | |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.012 | |
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.011 | |
| PDX1 | pancreatic and duodenal homeobox 1 | 0.011 | |
| AR | androgen receptor | 0.011 | |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.011 | |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.011 | |
| HNF1B | HNF1 homeobox B | 0.011 | |
| HOXC11 | homeobox C11 | 0.011 | |
| TGFB1 | transforming growth factor, beta 1 | 0.011 |