The network for 'actin filament bundle assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

actin filament bundle assembly

The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.

Mus musculus
Name Description Probability Func Analog Organism
Rac1 RAS-related C3 botulinum substrate 1 0.981
Vasp vasodilator-stimulated phosphoprotein 0.833
Ephb2 Eph receptor B2 0.825
Apc adenomatosis polyposis coli 0.817
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.793
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.781
Arrb2 arrestin, beta 2 0.606
Ptk2 PTK2 protein tyrosine kinase 2 0.593
Pxn paxillin 0.557
Myo7a myosin VIIA 0.552
Vangl1 vang-like 1 (van gogh, Drosophila) 0.549
Src Rous sarcoma oncogene 0.548
Ctnnb1 catenin (cadherin associated protein), beta 1 0.528
Enah enabled homolog (Drosophila) 0.517
Wdr1 WD repeat domain 1 0.514
Prkce protein kinase C, epsilon 0.492
Itga3 integrin alpha 3 0.461
Myo15 myosin XV 0.434
Ush1g Usher syndrome 1G homolog (human) 0.408
Hcls1 hematopoietic cell specific Lyn substrate 1 0.396
Abi1 abl-interactor 1 0.377
2310014H01Rik RIKEN cDNA 2310014H01 gene 0.375
Vangl2 vang-like 2 (van gogh, Drosophila) 0.372
Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 0.370
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.368
Efnb2 ephrin B2 0.352
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.339
Wnt3a wingless-related MMTV integration site 3A 0.313
Dnm1 dynamin 1 0.300
Actb actin, beta 0.300
Ephb3 Eph receptor B3 0.285
Tjp1 tight junction protein 1 0.263
Arpc4 actin related protein 2/3 complex, subunit 4 0.262
Lama5 laminin, alpha 5 0.262
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.254
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.253
Rnd3 Rho family GTPase 3 0.249
Ptprc protein tyrosine phosphatase, receptor type, C 0.246
Wwtr1 WW domain containing transcription regulator 1 0.235
Bcar1 breast cancer anti-estrogen resistance 1 0.234
Tgfb1 transforming growth factor, beta 1 0.233
Actn1 actinin, alpha 1 0.223
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.222
Smurf2 SMAD specific E3 ubiquitin protein ligase 2 0.218
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.214
Hck hemopoietic cell kinase 0.208
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.203
Wnt6 wingless-related MMTV integration site 6 0.199
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.195
Ptk7 PTK7 protein tyrosine kinase 7 0.191
Ptprq protein tyrosine phosphatase, receptor type, Q 0.190
Tsc2 tuberous sclerosis 2 0.185
Wnt4 wingless-related MMTV integration site 4 0.184
Was Wiskott-Aldrich syndrome homolog (human) 0.179
Rictor RPTOR independent companion of MTOR, complex 2 0.179
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.178
Msn moesin 0.177
Nf2 neurofibromatosis 2 0.176
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.176
Itgb3 integrin beta 3 0.175
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.175
Esr2 estrogen receptor 2 (beta) 0.170
Srebf2 sterol regulatory element binding factor 2 0.169
Smad4 MAD homolog 4 (Drosophila) 0.164
Nf1 neurofibromatosis 1 0.159
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.158
Apoe apolipoprotein E 0.156
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.155
Epha2 Eph receptor A2 0.150
Trp53 transformation related protein 53 0.150
Psap prosaposin 0.149
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.142
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.142
Litaf LPS-induced TN factor 0.141
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.140
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.139
Wipf1 WAS/WASL interacting protein family, member 1 0.138
Kit kit oncogene 0.137
Grxcr1 glutaredoxin, cysteine rich 1 0.137
Cttn cortactin 0.136
Krt7 keratin 7 0.136
Tinagl1 tubulointerstitial nephritis antigen-like 1 0.134
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.133
Braf Braf transforming gene 0.131
Fgfr1 fibroblast growth factor receptor 1 0.131
Sorbs3 sorbin and SH3 domain containing 3 0.128
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.126
Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.125
Dlg4 discs, large homolog 4 (Drosophila) 0.125
Ret ret proto-oncogene 0.124
Lhx1 LIM homeobox protein 1 0.122
Nfe2l3 nuclear factor, erythroid derived 2, like 3 0.121
Gli2 GLI-Kruppel family member GLI2 0.120
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.120
Tbx2 T-box 2 0.119
Lsp1 lymphocyte specific 1 0.118
Thbs1 thrombospondin 1 0.116
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.115
Inpp5d inositol polyphosphate-5-phosphatase D 0.115
Bcl2 B-cell leukemia/lymphoma 2 0.115
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
ina-1 Protein INA-1 0.052
mig-2 Protein MIG-2 0.042
pat-12 Protein PAT-12 0.041
R90.1 Protein R90.1 0.029
mpk-1 Protein MPK-1 0.028
sem-5 Protein SEM-5 0.027
M70.1 Protein M70.1 0.027
klp-3 Protein KLP-3 0.026
rme-4 Protein RME-4 0.026
unc-68 Protein UNC-68 0.023
C55C3.4 Protein C55C3.4 0.023
unc-43 Protein UNC-43 0.022
unc-15 Protein UNC-15 0.022
pkn-1 Protein PKN-1 0.021
CELE_C08F8.6 Protein C08F8.6 0.021
egl-27 Protein EGL-27 0.021
C11E4.6 Protein C11E4.6 0.020
pes-22 Protein PES-22 0.020
T23E7.2 Protein T23E7.2 0.020
sax-7 Protein SAX-7 0.020
mup-2 Protein MUP-2 0.020
F59C12.3 Protein F59C12.3 0.020
M02D8.1 Protein M02D8.1 0.019
unc-73 Protein UNC-73 0.019
CELE_M05D6.3 Protein M05D6.3 0.019
unc-112 Protein UNC-112 0.019
CELE_Y69A2AR.8 Protein Y69A2AR.8 0.019
CELE_Y57G11C.6 Protein Y57G11C.6 0.019
acs-6 Protein ACS-6 0.019
K10B4.3 Protein K10B4.3 0.019
C17H11.6 Protein C17H11.6 0.019
frm-3 Protein FRM-3 0.018
C27H2.2 Protein C27H2.2 0.018
vav-1 Protein VAV-1 0.018
goa-1 Protein GOA-1 0.018
C28C12.1 Protein C28C12.1 0.018
CELE_ZK354.2 Protein ZK354.2 0.017
T28B4.1 Protein T28B4.1 0.017
zfp-3 Protein ZFP-3 0.017
K07A3.3 Protein K07A3.3 0.017
CELE_T04H1.2 Protein T04H1.2 0.017
apg-1 Protein APG-1 0.017
pat-2 Protein PAT-2 0.017
T28F4.3 Protein T28F4.3 0.017
let-60 Protein LET-60 0.016
tag-163 Protein TAG-163 0.016
mrp-1 Protein MRP-1 0.016
ifa-1 Protein IFA-1 0.016
T19D12.5 Protein T19D12.5 0.016
T05A7.6 Protein T05A7.6 0.016
K09A9.6 Protein K09A9.6 0.016
C53B4.2 Protein C53B4.2 0.016
pdl-1 Protein PDL-1 0.016
ajm-1 Protein AJM-1 0.016
unc-52 Protein UNC-52 0.016
sorb-1 Protein SORB-1 0.016
obr-3 Protein OBR-3 0.016
hid-1 Protein HID-1 0.016
CELE_Y47G6A.13 Protein Y47G6A.13 0.015
mup-4 Protein MUP-4 0.015
etr-1 Protein ETR-1 0.015
CELE_W05H12.1 Protein W05H12.1 0.015
rsy-1 Protein RSY-1 0.015
T03G11.6 Protein T03G11.6 0.015
C06G1.5 Protein C06G1.5 0.015
B0379.7 Protein B0379.7 0.015
F55F8.7 Protein F55F8.7 0.015
F47B3.6 Protein F47B3.6 0.015
T13H5.6 Protein T13H5.6 0.015
CELE_C50F4.2 Protein C50F4.2 0.015
C43H6.4 Protein C43H6.4 0.015
CELE_C06C6.7 Protein C06C6.7 0.015
gcs-1 Protein GCS-1 0.015
twk-18 Protein TWK-18 0.015
C36F7.5 Protein C36F7.5 0.015
unc-116 Protein UNC-116 0.015
K10H10.7 Protein K10H10.7 0.015
CELE_AH6.3 Protein AH6.3 0.015
tmc-2 Protein TMC-2 0.015
CELE_F47G4.4 Protein F47G4.4 0.015
unc-115 Protein UNC-115 0.014
sax-3 Protein SAX-3 0.014
mek-2 Protein MEK-2 0.014
svh-2 Protein SVH-2 0.014
chd-7 Protein CHD-7 0.014
W03G1.2 Protein W03G1.2 0.014
CELE_F43G6.4 Protein F43G6.4 0.014
F53B3.3 Protein F53B3.3 0.014
ppfr-2 Protein PPFR-2 0.014
rgs-7 Protein RGS-7 0.014
daf-15 Protein DAF-15 0.014
T20F7.1 Protein T20F7.1 0.014
cwn-2 Protein CWN-2 0.014
ZK849.1 Protein ZK849.1 0.014
C14H10.2 Protein C14H10.2 0.014
Y106G6A.1 Protein Y106G6A.1 0.014
CELE_F54D5.15 Protein F54D5.15 0.014
deb-1 Protein DEB-1 0.014
trim-9 Protein TRIM-9 0.014
CELE_F55D12.2 Protein F55D12.2 0.014
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.868
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.447
itgb1b.2 integrin, beta 1b.2 0.178
rnd3a Rho family GTPase 3a 0.162
foxn4 forkhead box N4 0.160
itgb3b integrin beta 3b 0.158
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.140
bactin1 bactin1 0.134
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.111
pdlim1 PDZ and LIM domain 1 (elfin) 0.104
zgc:100942 zgc:100942 0.078
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.072
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.064
rras related RAS viral (r-ras) oncogene homolog 0.061
acvr1b activin A receptor, type IB 0.055
nrarpa notch-regulated ankyrin repeat protein a 0.054
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.051
ighz immunoglobulin heavy constant zeta 0.051
crabp2a cellular retinoic acid binding protein 2, a 0.049
lims1 LIM and senescent cell antigen-like domains 1 0.047
celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.046
pdlim2 PDZ and LIM domain 2 (mystique) 0.046
tie2 endothelium-specific receptor tyrosine kinase 2 0.045
itgb1b integrin, beta 1b 0.045
alcamb activated leukocyte cell adhesion molecule b 0.039
gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.037
itgav integrin, alpha V 0.037
msna moesin a 0.036
sh3gl1b SH3-domain GRB2-like 1b 0.035
zgc:85866 zgc:85866 0.033
cbfb core-binding factor, beta subunit 0.031
s100a10a S100 calcium binding protein A10a 0.031
gnas GNAS complex locus 0.031
igf1rb insulin-like growth factor 1b receptor 0.030
wnt9a wingless-type MMTV integration site family, member 9A 0.030
dtng dystrobrevin, gamma and dystrobrevin, gamma-like 0.029
itgb1a integrin, beta 1a 0.028
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.028
itgb1b.1 integrin, beta 1b.1 0.027
waca WW domain containing adaptor with coiled-coil a 0.024
gnal guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 0.024
syf2 SYF2 homolog, RNA splicing factor (S. cerevisiae) 0.023
six4.3 sine oculis homeobox homolog 4.3 0.023
cnn2 calponin 2 0.022
mmp2 matrix metalloproteinase 2 0.022
dvl2 dishevelled, dsh homolog 2 (Drosophila) 0.022
b2m beta-2-microglobulin 0.021
si:ch73-60e21.1 si:ch73-60e21.1 0.021
bactin2 bactin2 0.021
krt8 keratin 8 0.020
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.019
zgc:66100 zgc:66100 0.019
s100t S100 calcium binding protein T 0.018
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.018
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.018
gna14 guanine nucleotide binding protein (G protein), alpha 14 0.017
csrp1a cysteine and glycine-rich protein 1a 0.017
zgc:100829 zgc:100829 0.017
tpm4 tropomyosin 4 0.016
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.016
egr2b early growth response 2b 0.016
dynlt3 dynein, light chain, Tctex-type 3 0.016
gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 0.015
zgc:92392 zgc:92392 0.015
gsna gelsolin a 0.015
npdc1 neural proliferation, differentiation and control, 1 0.015
tgfb1a transforming growth factor, beta 1a 0.015
ighm immunoglobulin heavy constant mu and immunoglobulin heavy constant mu 0.014
im:7154036 im:7154036 0.014
neu3.2 sialidase 3.2 0.014
arl5c ADP-ribosylation factor-like 5C 0.014
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.014
zgc:92046 zgc:92046 0.014
ebf3 early B-cell factor 3 0.014
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.013
igfbp6b insulin-like growth factor binding protein 6b 0.013
s100b S100 calcium binding protein, beta (neural) 0.013
sec31a sec31 homolog A (S. cerevisiae) 0.013
myl9l myosin, light polypeptide 9, like 0.012
LOC100332929 guanine nucleotide-binding protein subunit alpha-15-like 0.012
foxo3b forkhead box O3b 0.012
inhbb inhibin, beta B 0.012
sb:cb81 sb:cb81 0.012
rhpn2 rhophilin, Rho GTPase binding protein 2 0.011
satb2 SATB homeobox 2 0.011
gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.011
per2 period homolog 2 (Drosophila) 0.011
foxn1 forkhead box N1 0.011
opn1sw2 opsin 1 (cone pigments), short-wave-sensitive 2 0.010
tpm3 tropomyosin 3 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
dsh dishevelled 0.994
Mad Mothers against dpp 0.976
Cdc42 CG12530 gene product from transcript CG12530-RA 0.869
mys myospheroid 0.853
Rho1 CG8416 gene product from transcript CG8416-RB 0.772
bsk basket 0.745
WASp CG1520 gene product from transcript CG1520-RA 0.669
rst roughest 0.656
Src64B Src oncogene at 64B 0.568
Rala Ras-related protein 0.519
par-1 CG8201 gene product from transcript CG8201-RA 0.514
Cip4 CG15015 gene product from transcript CG15015-RA 0.509
mbc myoblast city 0.459
hep hemipterous 0.438
msn misshapen 0.417
Pak PAK-kinase 0.376
kel kelch 0.302
fz frizzled 0.300
pum pumilio 0.291
Akt1 CG4006 gene product from transcript CG4006-RA 0.291
Rac1 CG2248 gene product from transcript CG2248-RA 0.289
Pc Polycomb 0.289
chic chickadee 0.287
zip zipper 0.286
Btk29A Btk family kinase at 29A 0.278
N Notch 0.271
kst karst 0.255
ttk tramtrack 0.246
Ras85D Ras oncogene at 85D 0.222
jar jaguar 0.214
flw flapwing 0.199
Pde11 Phosphodiesterase 11 0.195
arm armadillo 0.185
cindr CIN85 and CD2AP orthologue 0.184
drpr draper 0.177
mew multiple edematous wings 0.171
chb chromosome bows 0.154
Stat92E Signal-transducer and activator of transcription protein at 92E 0.150
Gef26 CG9491 gene product from transcript CG9491-RB 0.141
Glt Glutactin 0.131
ovo CG6824 gene product from transcript CG6824-RE 0.130
CG13962 CG13962 gene product from transcript CG13962-RA 0.129
mbt mushroom bodies tiny 0.126
mam mastermind 0.125
wun wunen 0.111
Su(H) Suppressor of Hairless 0.103
katanin-60 katanin 60 0.099
wupA wings up A 0.099
Ephrin CG1862 gene product from transcript CG1862-RA 0.096
dm diminutive 0.093
Atg1 Autophagy-specific gene 1 0.089
cta concertina 0.087
inx2 innexin 2 0.086
futsch CG34387 gene product from transcript CG34387-RC 0.085
Pvr PDGF- and VEGF-receptor related 0.081
Mtl Mig-2-like 0.077
enc encore 0.077
X11L CG5675 gene product from transcript CG5675-RB 0.076
Moe Moesin 0.074
Rab11 Rab-protein 11 0.074
fw furrowed 0.069
Abl Abl tyrosine kinase 0.068
fu fused 0.068
rok Rho-kinase 0.068
htl heartless 0.067
rap retina aberrant in pattern 0.066
Wnt5 Wnt oncogene analog 5 0.065
Ced-12 CG5336 gene product from transcript CG5336-RA 0.064
trio CG18214 gene product from transcript CG18214-RA 0.063
Vinc Vinculin 0.061
Rac2 CG8556 gene product from transcript CG8556-RA 0.061
H Hairless 0.059
Zasp66 Z band alternatively spliced PDZ-motif protein 66 0.059
Pak3 CG14895 gene product from transcript CG14895-RA 0.057
luna CG33473 gene product from transcript CG33473-RB 0.056
Traf4 TNF-receptor-associated factor 4 0.056
Dad Daughters against dpp 0.056
aop anterior open 0.056
CG17082 CG17082 gene product from transcript CG17082-RD 0.051
Lerp lysosomal enzyme receptor protein 0.050
hh hedgehog 0.050
Dhc64C Dynein heavy chain 64C 0.049
Hem HEM-protein 0.047
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.047
wts warts 0.047
Myo31DF Myosin 31DF 0.046
faf fat facets 0.042
cher cheerio 0.041
cora coracle 0.041
arr arrow 0.040
CG3563 CG3563 gene product from transcript CG3563-RA 0.040
rols rolling pebbles 0.040
Vrp1 Verprolin 1 0.038
gish gilgamesh 0.038
hts hu li tai shao 0.038
tmod tropomodulin 0.037
dy dusky 0.037
tkv thickveins 0.037
otk off-track 0.037
milt milton 0.036
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.990
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.987
RHOA ras homolog gene family, member A 0.987
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.978
FYN FYN oncogene related to SRC, FGR, YES 0.962
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.958
FN1 fibronectin 1 0.946
FLNA filamin A, alpha 0.921
EGFR epidermal growth factor receptor 0.898
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.896
GRB2 growth factor receptor-bound protein 2 0.756
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.741
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.727
HCK hemopoietic cell kinase 0.705
SORBS3 sorbin and SH3 domain containing 3 0.695
ZYX zyxin 0.651
SH3KBP1 SH3-domain kinase binding protein 1 0.627
S100A6 S100 calcium binding protein A6 0.612
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.602
NCK1 NCK adaptor protein 1 0.506
WIPF1 WAS/WASL interacting protein family, member 1 0.474
S100A8 S100 calcium binding protein A8 0.469
SFN stratifin 0.444
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.437
BAIAP2 BAI1-associated protein 2 0.417
ARHGAP1 Rho GTPase activating protein 1 0.403
TSC2 tuberous sclerosis 2 0.395
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.388
MYH9 myosin, heavy chain 9, non-muscle 0.368
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.366
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.342
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.334
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.332
ZNF746 zinc finger protein 746 0.313
S100A9 S100 calcium binding protein A9 0.312
S100B S100 calcium binding protein B 0.309
S100A1 S100 calcium binding protein A1 0.288
VASP vasodilator-stimulated phosphoprotein 0.253
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.250
ABI1 abl-interactor 1 0.250
BCAR1 breast cancer anti-estrogen resistance 1 0.244
COTL1 coactosin-like 1 (Dictyostelium) 0.232
CTGF connective tissue growth factor 0.224
MAPK8 mitogen-activated protein kinase 8 0.215
FLNB filamin B, beta 0.214
CFL1 cofilin 1 (non-muscle) 0.212
PLEC plectin 0.204
LMNA lamin A/C 0.201
CTTN cortactin 0.194
EPS8 epidermal growth factor receptor pathway substrate 8 0.192
HP haptoglobin 0.182
A2M alpha-2-macroglobulin 0.178
SPRY4 sprouty homolog 4 (Drosophila) 0.176
WASF2 WAS protein family, member 2 0.176
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.173
SYK spleen tyrosine kinase 0.170
MSN moesin 0.168
TPM4 tropomyosin 4 0.163
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.162
ANXA2 annexin A2 0.160
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.157
PXN paxillin 0.156
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.149
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.148
ACTB actin, beta 0.136
HIPK3 homeodomain interacting protein kinase 3 0.134
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.133
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.129
PALLD palladin, cytoskeletal associated protein 0.129
FBLN1 fibulin 1 0.128
SPRR2A small proline-rich protein 2A 0.126
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.123
SPAG9 sperm associated antigen 9 0.120
PDCD6IP programmed cell death 6 interacting protein 0.120
FMNL1 formin-like 1 0.118
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.114
LRRK2 leucine-rich repeat kinase 2 0.113
ARRB2 arrestin, beta 2 0.112
ATXN1 ataxin 1 0.112
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.111
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.107
VAV1 vav 1 guanine nucleotide exchange factor 0.105
S100A11 S100 calcium binding protein A11 0.102
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.099
HTT huntingtin 0.098
VCL vinculin 0.096
ARRB1 arrestin, beta 1 0.095
ACTN1 actinin, alpha 1 0.094
CWC22 CWC22 spliceosome-associated protein homolog (S. cerevisiae) 0.093
RHOC ras homolog gene family, member C 0.092
RIN1 Ras and Rab interactor 1 0.089
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.087
ZNF496 zinc finger protein 496 0.087
FERMT2 fermitin family member 2 0.085
LST1 leukocyte specific transcript 1 0.085
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.084
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.084
TENC1 tensin like C1 domain containing phosphatase (tensin 2) 0.083
PICALM phosphatidylinositol binding clathrin assembly protein 0.082
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Efhd2 EF-hand domain family, member D2 0.409
Myh9 myosin, heavy chain 9, non-muscle 0.386
Ptprc protein tyrosine phosphatase, receptor type, C 0.154
Wdr1 WD repeat domain 1 0.136
Arpc1b actin related protein 2/3 complex, subunit 1B 0.124
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.110
Coro1a coronin, actin binding protein 1A 0.096
Cd53 Cd53 molecule 0.082
Cd38 CD38 molecule 0.081
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.070
Tagln transgelin 0.067
Acta2 smooth muscle alpha-actin 0.066
Hck hemopoietic cell kinase 0.060
Laptm5 lysosomal protein transmembrane 5 0.056
Tgfb1 transforming growth factor, beta 1 0.054
Inpp5d inositol polyphosphate-5-phosphatase D 0.053
Ptbp1 polypyrimidine tract binding protein 1 0.052
Emp1 epithelial membrane protein 1 0.052
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.051
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.041
Flna filamin A, alpha 0.041
Jak2 Janus kinase 2 0.040
RT1-DMb RT1 class II, locus DMb 0.040
Smad3 SMAD family member 3 0.040
Hcls1 hematopoietic cell specific Lyn substrate 1 0.039
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.038
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.036
Fgfr1 Fibroblast growth factor receptor 1 0.036
Iqgap1 IQ motif containing GTPase activating protein 1 0.035
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.035
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.033
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.032
Actn1 actinin, alpha 1 0.032
Ddr1 discoidin domain receptor tyrosine kinase 1 0.032
Cd44 Cd44 molecule 0.032
Lamc1 laminin, gamma 1 0.031
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.031
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.031
Anxa2 annexin A2 0.030
Msn moesin 0.030
Col12a1 collagen, type XII, alpha 1 0.029
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.028
Fn1 fibronectin 1 0.027
Sbf1 SET binding factor 1 0.027
Rara retinoic acid receptor, alpha 0.027
Akt2 v-akt murine thymoma viral oncogene homolog 2 0.026
Syk spleen tyrosine kinase 0.026
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.025
Cd4 Cd4 molecule 0.025
Lmna lamin A 0.025
Cdc2l5 cell division cycle 2-like 5 (cholinesterase-related cell division controller) 0.025
Gad1 glutamate decarboxylase 1 0.025
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.025
Myh11 myosin, heavy chain 11, smooth muscle 0.024
Map3k3 mitogen activated protein kinase kinase kinase 3 0.024
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.024
Fgfr2 fibroblast growth factor receptor 2 0.023
Cybb cytochrome b-245, beta polypeptide 0.022
RT1-DMa RT1 class II, locus DMa 0.022
Syt8 synaptotagmin VIII 0.022
Cald1 caldesmon 1 0.022
Glp1r glucagon-like peptide 1 receptor 0.022
Prkcd protein kinase C, delta 0.022
Pdzd4 PDZ domain containing 4 0.022
Dlg3 discs, large homolog 3 (Drosophila) 0.022
Anxa1 annexin A1 0.022
Sla src-like adaptor 0.022
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.021
Sptbn1 spectrin, beta, non-erythrocytic 1 0.021
Myl9 myosin, light chain 9, regulatory 0.021
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.021
Dstn destrin 0.020
Lrrfip1 leucine rich repeat (in FLII) interacting protein 1 0.020
Klf6 Kruppel-like factor 6 0.020
Fmnl1 formin-like 1 0.020
Cd37 CD37 molecule 0.020
Stat6 signal transducer and activator of transcription 6 0.019
Fkbp1a FK506 binding protein 1a 0.019
Lcp1 lymphocyte cytosolic protein 1 0.019
Cd247 Cd247 molecule 0.019
Lcp2 lymphocyte cytosolic protein 2 0.019
Lypd3 Ly6/Plaur domain containing 3 0.019
Shank2 SH3 and multiple ankyrin repeat domains 2 0.019
Arpc2 actin related protein 2/3 complex, subunit 2 0.019
Tagln2 transgelin 2 0.019
Sirpa signal-regulatory protein alpha 0.019
Calcr calcitonin receptor 0.018
Vav1 vav 1 guanine nucleotide exchange factor 0.018
Ncan neurocan 0.018
Tyrobp Tyro protein tyrosine kinase binding protein 0.018
Eef2 eukaryotic translation elongation factor 2 0.018
Actb actin, beta 0.017
Acvr1 activin A receptor, type I 0.017
S100a11 S100 calcium binding protein A11 (calizzarin) 0.017
Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase 0.017
Id2 inhibitor of DNA binding 2 0.017
Timp3 TIMP metallopeptidase inhibitor 3 0.017
Tgfbr2 transforming growth factor, beta receptor II 0.016
Ina internexin neuronal intermediate filament protein, alpha 0.016
Rac1 ras-related C3 botulinum toxin substrate 1 0.016
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MYO5 Myo5p 0.540
RHO1 Rho1p 0.352
CDC42 Cdc42p 0.179
GIC1 Gic1p 0.176
BUD6 Bud6p 0.168
BNI1 Bni1p 0.132
BEM3 Bem3p 0.097
RDI1 Rdi1p 0.094
CDC12 Cdc12p 0.093
ACT1 Act1p 0.092
MYO2 Myo2p 0.073
YSC84 Ysc84p 0.073
CMD1 Cmd1p 0.072
AVO1 Avo1p 0.067
PEA2 Pea2p 0.064
CDC55 Cdc55p 0.057
SRV2 Srv2p 0.057
ABP1 Abp1p 0.056
CDC11 Cdc11p 0.050
EXO70 Exo70p 0.049
CAM1 Cam1p 0.046
RVS167 Rvs167p 0.046
SCP1 Scp1p 0.045
TEF1 Tef1p 0.045
CDC24 Cdc24p 0.044
ARP2 Arp2p 0.043
FUS1 Fus1p 0.042
MLC1 Mlc1p 0.041
PAN1 Pan1p 0.039
YRB1 Yrb1p 0.036
SGE1 Sge1p 0.036
AIP1 Aip1p 0.034
TPM1 Tpm1p 0.033
MEX67 Mex67p 0.032
MYO3 Myo3p 0.031
GEA2 Gea2p 0.030
SKT5 Skt5p 0.029
MMF1 Mmf1p 0.029
SAP1 Sap1p 0.028
TCO89 Tco89p 0.028
BEM4 Bem4p 0.028
DBP5 Dbp5p 0.027
MER1 Mer1p 0.027
YGL015C hypothetical protein 0.026
NBP2 Nbp2p 0.026
YLR042C hypothetical protein 0.026
ENT2 Ent2p 0.026
COF1 Cof1p 0.026
TAO3 Tao3p 0.025
MOB2 Mob2p 0.024
ARP10 Arp10p 0.024
GYL1 Gyl1p 0.024
CHS6 Chs6p 0.024
SLA2 Sla2p 0.023
BCK1 Bck1p 0.023
AVO2 Avo2p 0.022
CNB1 Cnb1p 0.022
INP52 Inp52p 0.022
YLR264C-A hypothetical protein 0.022
BNR1 Bnr1p 0.021
SRD1 Srd1p 0.021
YLR162W hypothetical protein 0.021
YGR126W hypothetical protein 0.020
KOG1 Kog1p 0.020
THG1 Thg1p 0.020
SPA2 Spa2p 0.020
CRN1 Crn1p 0.020
YOL038C-A hypothetical protein 0.020
BSP1 Bsp1p 0.020
ARG8 Arg8p 0.019
CUP1-1 Cup1-1p 0.019
TEF2 Tef2p 0.019
CHA1 Cha1p 0.018
SGM1 Sgm1p 0.018
LEU2 Leu2p 0.018
UBP7 Ubp7p 0.018
ADH2 Adh2p 0.018
BUD8 Bud8p 0.018
SPL2 Spl2p 0.017
RHO4 Rho4p 0.017
URA3 Ura3p 0.017
SSO2 Sso2p 0.017
ARC19 Arc19p 0.017
DUG1 Dug1p 0.017
YLR126C hypothetical protein 0.016
PRP28 Prp28p 0.016
PEF1 Pef1p 0.016
URA1 Ura1p 0.016
SEN54 Sen54p 0.016
YLR108C hypothetical protein 0.016
YAR068W hypothetical protein 0.016
DIF1 Dif1p 0.016
HHT2 Hht2p 0.016
REE1 Ree1p 0.016
MNT2 Mnt2p 0.015
ARP3 Arp3p 0.015
YIL151C hypothetical protein 0.015
MAK3 Mak3p 0.015
MSB4 Msb4p 0.015
HNT1 Hnt1p 0.015