IMP
Process View
The network for 'cell proliferation involved in heart valve development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cell proliferation involved in heart valve development
Any cell proliferation that is involved in heart valve development.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Smad4 | MAD homolog 4 (Drosophila) | 1.000 | |
| Gata4 | GATA binding protein 4 | 0.984 | |
| Smad1 | MAD homolog 1 (Drosophila) | 0.979 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.969 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.961 | |
| Pax6 | paired box gene 6 | 0.954 | |
| Shh | sonic hedgehog | 0.934 | |
| Axin1 | axin 1 | 0.897 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.862 | |
| Neurog2 | neurogenin 2 | 0.757 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.755 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.718 | |
| En1 | engrailed 1 | 0.694 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.678 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.653 | |
| Msx1 | homeobox, msh-like 1 | 0.652 | |
| Efna2 | ephrin A2 | 0.652 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.645 | |
| Dlx2 | distal-less homeobox 2 | 0.632 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.619 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.597 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.567 | |
| Onecut1 | one cut domain, family member 1 | 0.549 | |
| Fgf8 | fibroblast growth factor 8 | 0.521 | |
| Neurod1 | neurogenic differentiation 1 | 0.517 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.502 | |
| Erbb2ip | Erbb2 interacting protein | 0.435 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.431 | |
| Smad2 | MAD homolog 2 (Drosophila) | 0.429 | |
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.425 | |
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.418 | |
| Pax3 | paired box gene 3 | 0.412 | |
| Apc | adenomatosis polyposis coli | 0.401 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.397 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.391 | |
| Gata6 | GATA binding protein 6 | 0.380 | |
| Foxc2 | forkhead box C2 | 0.368 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.359 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.352 | |
| Bmp4 | bone morphogenetic protein 4 | 0.346 | |
| Meox2 | mesenchyme homeobox 2 | 0.343 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.331 | |
| Neurod4 | neurogenic differentiation 4 | 0.331 | |
| Nhlh1 | nescient helix loop helix 1 | 0.321 | |
| Gata1 | GATA binding protein 1 | 0.312 | |
| Mecom | MDS1 and EVI1 complex locus | 0.303 | |
| Hoxd3 | homeobox D3 | 0.301 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.292 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.291 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.290 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.274 | |
| Prrx1 | paired related homeobox 1 | 0.270 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.265 | |
| Tbx3 | T-box 3 | 0.251 | |
| Prph2 | peripherin 2 | 0.242 | |
| Prrx2 | paired related homeobox 2 | 0.241 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.232 | |
| Neurog1 | neurogenin 1 | 0.231 | |
| Myod1 | myogenic differentiation 1 | 0.226 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.214 | |
| Hoxa1 | homeobox A1 | 0.206 | |
| Sox11 | SRY-box containing gene 11 | 0.201 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.195 | |
| Smad7 | MAD homolog 7 (Drosophila) | 0.195 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.189 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.188 | |
| Rnf111 | ring finger 111 | 0.185 | |
| Ebf3 | early B-cell factor 3 | 0.181 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.180 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.180 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.178 | |
| Alx3 | aristaless-like homeobox 3 | 0.177 | |
| Acvr1 | activin A receptor, type 1 | 0.172 | |
| Runx2 | runt related transcription factor 2 | 0.166 | |
| Pten | phosphatase and tensin homolog | 0.166 | |
| Sim2 | single-minded homolog 2 (Drosophila) | 0.165 | |
| Bmp2 | bone morphogenetic protein 2 | 0.162 | |
| Hoxc5 | homeobox C5 | 0.159 | |
| Tbx5 | T-box 5 | 0.156 | |
| Smurf1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.156 | |
| Gsc | goosecoid homeobox | 0.155 | |
| Hoxd13 | homeobox D13 | 0.155 | |
| Trp53 | transformation related protein 53 | 0.149 | |
| Hoxd1 | homeobox D1 | 0.146 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.142 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.141 | |
| Sox9 | SRY-box containing gene 9 | 0.141 | |
| Fgf15 | fibroblast growth factor 15 | 0.141 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.138 | |
| Nkx3-2 | NK3 homeobox 2 | 0.137 | |
| Ebf2 | early B-cell factor 2 | 0.136 | |
| Shox2 | short stature homeobox 2 | 0.134 | |
| Col22a1 | collagen, type XXII, alpha 1 | 0.133 | |
| Myog | myogenin | 0.132 | |
| Lhx9 | LIM homeobox protein 9 | 0.131 | |
| Lhx5 | LIM homeobox protein 5 | 0.131 | |
| Lhx3 | LIM homeobox protein 3 | 0.129 | |
| Pax9 | paired box gene 9 | 0.128 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.127 | |
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.123 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.994 | |
| SKIL | SKI-like oncogene | 0.979 | |
| GATA2 | GATA binding protein 2 | 0.881 | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.869 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.845 | |
| SMAD3 | SMAD family member 3 | 0.811 | |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.731 | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.711 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.663 | |
| SMAD2 | SMAD family member 2 | 0.648 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.579 | |
| SP1 | Sp1 transcription factor | 0.427 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.424 | |
| HTT | huntingtin | 0.368 | |
| RUNX1 | runt-related transcription factor 1 | 0.308 | |
| SMAD1 | SMAD family member 1 | 0.306 | |
| CXXC5 | CXXC finger protein 5 | 0.250 | |
| TCF12 | transcription factor 12 | 0.207 | |
| DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.201 | |
| SMAD5 | SMAD family member 5 | 0.176 | |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.152 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.120 | |
| PDX1 | pancreatic and duodenal homeobox 1 | 0.118 | |
| DCP1B | DCP1 decapping enzyme homolog B (S. cerevisiae) | 0.111 | |
| LYL1 | lymphoblastic leukemia derived sequence 1 | 0.103 | |
| NLK | nemo-like kinase | 0.093 | |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | 0.084 | |
| POU4F2 | POU class 4 homeobox 2 | 0.076 | |
| TRIM33 | tripartite motif containing 33 | 0.072 | |
| ATF7IP | activating transcription factor 7 interacting protein | 0.071 | |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.068 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.068 | |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.067 | |
| GATA4 | GATA binding protein 4 | 0.064 | |
| HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.061 | |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.058 | |
| ZBED5 | zinc finger, BED-type containing 5 | 0.057 | |
| TSC22D1 | TSC22 domain family, member 1 | 0.057 | |
| YY1 | YY1 transcription factor | 0.057 | |
| SMAD6 | SMAD family member 6 | 0.054 | |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.053 | |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.052 | |
| MYOD1 | myogenic differentiation 1 | 0.049 | |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.049 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.043 | |
| HOXD12 | homeobox D12 | 0.041 | |
| AR | androgen receptor | 0.040 | |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.040 | |
| DACH1 | dachshund homolog 1 (Drosophila) | 0.038 | |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.038 | |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.037 | |
| FGF3 | fibroblast growth factor 3 | 0.034 | |
| HAND2 | heart and neural crest derivatives expressed 2 | 0.033 | |
| LHX5 | LIM homeobox 5 | 0.033 | |
| LMO1 | LIM domain only 1 (rhombotin 1) | 0.033 | |
| NCOR1 | nuclear receptor corepressor 1 | 0.032 | |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 | 0.032 | |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.032 | |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.032 | |
| ELAVL2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.031 | |
| FEV | FEV (ETS oncogene family) | 0.030 | |
| SPTBN4 | spectrin, beta, non-erythrocytic 4 | 0.030 | |
| CDK6 | cyclin-dependent kinase 6 | 0.029 | |
| LRRN2 | leucine rich repeat neuronal 2 | 0.028 | |
| SIX6 | SIX homeobox 6 | 0.028 | |
| POU4F3 | POU class 4 homeobox 3 | 0.028 | |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.027 | |
| MNX1 | motor neuron and pancreas homeobox 1 | 0.027 | |
| HOXD13 | homeobox D13 | 0.026 | |
| SFRP5 | secreted frizzled-related protein 5 | 0.025 | |
| HOXB9 | homeobox B9 | 0.025 | |
| FOXF2 | forkhead box F2 | 0.025 | |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 0.025 | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.024 | |
| FOXB1 | forkhead box B1 | 0.024 | |
| HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.023 | |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | 0.023 | |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.023 | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.023 | |
| HAP1 | huntingtin-associated protein 1 | 0.023 | |
| YAP1 | Yes-associated protein 1 | 0.023 | |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.022 | |
| FEZF2 | FEZ family zinc finger 2 | 0.022 | |
| ELK1 | ELK1, member of ETS oncogene family | 0.021 | |
| SNIP1 | Smad nuclear interacting protein 1 | 0.020 | |
| POU2F1 | POU class 2 homeobox 1 | 0.020 | |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.019 | |
| HOXA5 | homeobox A5 | 0.019 | |
| CCND1 | cyclin D1 | 0.018 | |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.018 | |
| EDC4 | enhancer of mRNA decapping 4 | 0.018 | |
| SLC9A3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.018 | |
| TESC | tescalcin | 0.018 | |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.017 | |
| MTMR10 | myotubularin related protein 10 | 0.017 | |
| HOXD8 | homeobox D8 | 0.017 | |
| VSX1 | visual system homeobox 1 | 0.017 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.017 | |
| GMEB1 | glucocorticoid modulatory element binding protein 1 | 0.017 | |
| NPAS1 | neuronal PAS domain protein 1 | 0.017 |