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Process View

Drosophila melanogaster

13 genes annotated in fly

double strand break repair via homologous recombination

The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.

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In addition to gene-name show these genes:

Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "double strand break repair via homologous recombination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "double strand break repair via homologous recombination" (in gray)

Name	Description	Probability	Func Analog Organism
mus205	mutagen-sensitive 205	0.998
lok	loki	0.970
mei-9	meiotic 9	0.944
DNApol-eta	CG7143 gene product from transcript CG7143-RA	0.928
spn-B	spindle B	0.919	Human
Brca2	Breast cancer 2, early onset homolog	0.910
rad50	CG6339 gene product from transcript CG6339-RD	0.905
mus301	mutagen-sensitive 301	0.894	Human
RecQ5	homolog of RecQ	0.864
mus101	mutagen-sensitive 101	0.841
CG5524	CG5524 gene product from transcript CG5524-RA	0.828
okr	okra	0.786
RfC3	Replication factor C subunit 3	0.664
mei-41	meiotic 41	0.647
spn-A	spindle A	0.632
RnrL	Ribonucleoside diphosphate reductase large subunit	0.622
mus308	mutagen-sensitive 308	0.551
Mcm5	Minichromosome maintenance 5	0.549	Yeast
CDC45L	CG3658 gene product from transcript CG3658-RA	0.474	Yeast
Mcm2	Minichromosome maintenance 2	0.420	Yeast
Mcm3	Minichromosome maintenance 3	0.406	Yeast
Irbp	Inverted repeat-binding protein	0.374
p53	CG33336 gene product from transcript CG33336-RB	0.341
mus201	mutagen-sensitive 201	0.325	Worm
Ercc1	CG10215 gene product from transcript CG10215-RA	0.303
RecQ4	CG7487 gene product from transcript CG7487-RA	0.275
Smc5	CG32438 gene product from transcript CG32438-RE	0.212
dmt	dalmatian	0.204
hay	haywire	0.204
mus309	mutagen-sensitive 309	0.191
Mcm7	Minichromosome maintenance 7	0.183	Yeast
MAGE	CG10059 gene product from transcript CG10059-RA	0.179
nbs	CG6754 gene product from transcript CG6754-RC	0.163
mus312	mutagen-sensitive 312	0.136
mre11	meiotic recombination 11	0.106	Yeast
zuc	zucchini	0.086
RPA2	Replication protein A2	0.080	Human
CG13350	CG13350 gene product from transcript CG13350-RA	0.072
mus304	mutagen-sensitive 304	0.066
Psf3	CG2222 gene product from transcript CG2222-RA	0.065	Yeast
RpA-70	Replication Protein A 70	0.059	Human
CG9576	CG9576 gene product from transcript CG9576-RA	0.056
spn-D	spindle D	0.053	Human
defl	deflated	0.052
Mnn1	Menin 1	0.050
CG7544	CG7544 gene product from transcript CG7544-RA	0.050
CG5857	CG5857 gene product from transcript CG5857-RA	0.049
rasp	CG11495 gene product from transcript CG11495-RA	0.047
DNApol-alpha50	DNA polymerase alpha 50kD	0.045
CG18271	CG18271 gene product from transcript CG18271-RB	0.040
Chrac-14	CG13399 gene product from transcript CG13399-RA	0.038
CG3430	CG3430 gene product from transcript CG3430-RA	0.033
CG2694	CG2694 gene product from transcript CG2694-RA	0.033
WRNexo	WRN exonuclease	0.033
CG16838	CG16838 gene product from transcript CG16838-RC	0.032
Cks30A	Cyclin-dependent kinase subunit 30A	0.030
imd	immune deficiency	0.029
Utx	CG5640 gene product from transcript CG5640-RD	0.027
Cka	Connector of kinase to AP-1	0.026
Lrr47	Leucine-rich repeat 47	0.025
Mcm10	Sensitized chromosome inheritance modifier 19	0.025
Caf1-105	CG12892 gene product from transcript CG12892-RA	0.025
CG9752	CG9752 gene product from transcript CG9752-RA	0.024
CG15220	CG15220 gene product from transcript CG15220-RA	0.023
BCL7-like	CG17252 gene product from transcript CG17252-RA	0.023
cort	cortex	0.022
Psf1	CG9187 gene product from transcript CG9187-RA	0.022	Yeast
Rpn9	CG10230 gene product from transcript CG10230-RB	0.022
RanGap	Ran GTPase activating protein	0.021
CG9772	CG9772 gene product from transcript CG9772-RB	0.021
CG4680	CG4680 gene product from transcript CG4680-RA	0.021
Rev1	CG12189 gene product from transcript CG12189-RA	0.021
JhI-1	Juvenile hormone-inducible protein 1	0.021
CG10445	CG10445 gene product from transcript CG10445-RC	0.020
CycH	Cyclin H	0.020
Tbp-1	Tat-binding protein-1	0.020
Mcm6	Minichromosome maintenance 6	0.019	Yeast
Ts	CG3181 gene product from transcript CG3181-RA	0.018
CG2990	CG2990 gene product from transcript CG2990-RB	0.018
nopo	no poles	0.017
mus210	mutagen-sensitive 210	0.016
CG4496	CG4496 gene product from transcript CG4496-RA	0.016
DNApol-alpha73	DNA polymerase alpha 73kD	0.015
ranshi	CG9793 gene product from transcript CG9793-RA	0.014
hdm	hold'em	0.014
CG3815	CG3815 gene product from transcript CG3815-RA	0.014
png	pan gu	0.014
RnrS	Ribonucleoside diphosphate reductase small subunit	0.014
ari-1	ariadne	0.013
Shc	SHC-adaptor protein	0.013
CG1575	CG1575 gene product from transcript CG1575-RA	0.013
Snap25	Synapse protein 25	0.013
RfC4	Replication factor C subunit 4	0.013
HipHop	HP1-HOAP-interacting protein	0.013
CG11403	CG11403 gene product from transcript CG11403-RA	0.013
Orc1	Origin recognition complex subunit 1	0.013
Rpn1	CG7762 gene product from transcript CG7762-RA	0.013
CG32251	CG32251 gene product from transcript CG32251-RA	0.012
CG31998	CG31998 gene product from transcript CG31998-RA	0.012
tos	tosca	0.012
Rpn3	Regulatory particle non-ATPase 3	0.012
Tfb5	CG42373 gene product from transcript CG42373-RB	0.011
Rassf	Ras association family member	0.011
CG8142	CG8142 gene product from transcript CG8142-RA	0.011
Dok	Downstream of kinase	0.011
asf1	anti-silencing factor 1	0.011
Cap-D3	Chromosome associated protein D3	0.011
Orc5	Origin recognition complex subunit 5	0.011
dpa	disc proliferation abnormal	0.010	Yeast