IMP

Process View

Homo sapiens

3 genes annotated in human

Multi-species View

apoptotic process involved in morphogenesis

GO:0060561

Any apoptotic process that contributes to the shaping of an anatomical structure.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic process involved in morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "apoptotic process involved in morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2L1	BCL2-like 1	0.991
BCL2	B-cell CLL/lymphoma 2	0.990
BAK1	BCL2-antagonist/killer 1	0.982
BAX	BCL2-associated X protein	0.924	Mouse
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.881
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.868
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.789	Mouse
BAD	BCL2-associated agonist of cell death	0.751
TBX5	T-box 5	0.705
RXRA	retinoid X receptor, alpha	0.703
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.619
RUNX1	runt-related transcription factor 1	0.565
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.533
BID	BH3 interacting domain death agonist	0.508
BECN1	beclin 1, autophagy related	0.415
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.414
JAG1	jagged 1	0.381
NOTCH3	notch 3	0.370
TP53BP2	tumor protein p53 binding protein, 2	0.332
HIPK2	homeodomain interacting protein kinase 2	0.319
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.316
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.259
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.256
BIK	BCL2-interacting killer (apoptosis-inducing)	0.216
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.198
BBC3	BCL2 binding component 3	0.189
HR	hairless homolog (mouse)	0.187
RNF144B	ring finger protein 144B	0.167
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.164
CDK6	cyclin-dependent kinase 6	0.148
GATA4	GATA binding protein 4	0.147
RNR2	l-rRNA	0.145
FKBP8	FK506 binding protein 8, 38kDa	0.143
NKX2-1	NK2 homeobox 1	0.143
ZFYVE9	zinc finger, FYVE domain containing 9	0.139
HUWE1	HECT, UBA and WWE domain containing 1	0.134
GFI1B	growth factor independent 1B transcription repressor	0.133
PKP4	plakophilin 4	0.127
APC	adenomatous polyposis coli	0.125
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.111
TAL1	T-cell acute lymphocytic leukemia 1	0.111
CTGF	connective tissue growth factor	0.099
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.089
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.089
HNF1A	HNF1 homeobox A	0.082
AMBRA1	autophagy/beclin-1 regulator 1	0.076
CCND3	cyclin D3	0.074
BANP	BTG3 associated nuclear protein	0.073
NOG	noggin	0.071
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.067
RARA	retinoic acid receptor, alpha	0.064
GSK3B	glycogen synthase kinase 3 beta	0.060
CREBBP	CREB binding protein	0.059
EP300	E1A binding protein p300	0.049
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.048
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.044
BBS1	Bardet-Biedl syndrome 1	0.042
MAPK7	mitogen-activated protein kinase 7	0.042
DAXX	death-domain associated protein	0.041
HOXA10	homeobox A10	0.041
BCL2L2	BCL2-like 2	0.041
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.041
HOXB5	homeobox B5	0.040
NOTCH1	notch 1	0.039	Mouse
MAPK8	mitogen-activated protein kinase 8	0.039
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.037
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.036
ATN1	atrophin 1	0.035
AMOTL2	angiomotin like 2	0.035
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.035
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.035
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.034
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.033
PSEN1	presenilin 1	0.031
SFN	stratifin	0.029
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.027
ELF4	E74-like factor 4 (ets domain transcription factor)	0.027
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.027
CAPRIN2	caprin family member 2	0.027
HOXD13	homeobox D13	0.027
EGFL7	EGF-like-domain, multiple 7	0.027
PDX1	pancreatic and duodenal homeobox 1	0.026
PAX8	paired box 8	0.026	Mouse
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.026
HOXA11	homeobox A11	0.026
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.026
AXIN1	axin 1	0.025
CCND1	cyclin D1	0.025
LBX1	ladybird homeobox 1	0.024
MAML1	mastermind-like 1 (Drosophila)	0.024
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.024
GRHL3	grainyhead-like 3 (Drosophila)	0.024
SNAI1	snail homolog 1 (Drosophila)	0.024
NAF1	nuclear assembly factor 1 homolog (S. cerevisiae)	0.023
PYY	peptide YY	0.023
HOXA5	homeobox A5	0.023
HOXB7	homeobox B7	0.023
NEUROG3	neurogenin 3	0.023
SPNS1	spinster homolog 1 (Drosophila)	0.023
TGIF1	TGFB-induced factor homeobox 1	0.023
DLL1	delta-like 1 (Drosophila)	0.022
HES2	hairy and enhancer of split 2 (Drosophila)	0.022
TJP2	tight junction protein 2 (zona occludens 2)	0.022
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.022
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.022
PPME1	protein phosphatase methylesterase 1	0.022
DMXL1	Dmx-like 1	0.022
CDX2	caudal type homeobox 2	0.022
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.021
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.021
XIAP	X-linked inhibitor of apoptosis	0.021
HNF1B	HNF1 homeobox B	0.021	Mouse
TFG	TRK-fused gene	0.021
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.021
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.021
FOXD3	forkhead box D3	0.020
HOXB9	homeobox B9	0.020
FOXA2	forkhead box A2	0.020
WNT10A	wingless-type MMTV integration site family, member 10A	0.019
HOXA7	homeobox A7	0.019
ZFYVE1	zinc finger, FYVE domain containing 1	0.019
HOXD9	homeobox D9	0.019
FXYD3	FXYD domain containing ion transport regulator 3	0.019
GFI1	growth factor independent 1 transcription repressor	0.018
NELL2	NEL-like 2 (chicken)	0.018
NEK7	NIMA (never in mitosis gene a)-related kinase 7	0.018
AGRN	agrin	0.018
FOXN4	forkhead box N4	0.018
TRIP6	thyroid hormone receptor interactor 6	0.018
SIM2	single-minded homolog 2 (Drosophila)	0.018
STK25	serine/threonine kinase 25	0.018
PAX2	paired box 2	0.018	Mouse
PAX7	paired box 7	0.018
MAPK1	mitogen-activated protein kinase 1	0.018
MED25	mediator complex subunit 25	0.018
HOXD10	homeobox D10	0.018
SP1	Sp1 transcription factor	0.017
HOXC6	homeobox C6	0.017
PHOX2A	paired-like homeobox 2a	0.017
NOTCH2	notch 2	0.017
GATA5	GATA binding protein 5	0.017
SFRP5	secreted frizzled-related protein 5	0.017
JAG2	jagged 2	0.017	Mouse
TBX2	T-box 2	0.017
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.017
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.017
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.017
OTP	orthopedia homeobox	0.016
SIX6	SIX homeobox 6	0.016
WT1	Wilms tumor 1	0.016
HOXD11	homeobox D11	0.016
EGR1	early growth response 1	0.016
LHX1	LIM homeobox 1	0.016
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.016
PITX2	paired-like homeodomain 2	0.016
STRN3	striatin, calmodulin binding protein 3	0.015
PPP5C	protein phosphatase 5, catalytic subunit	0.015
PSEN2	presenilin 2 (Alzheimer disease 4)	0.015
OVOL1	ovo-like 1(Drosophila)	0.015
WNT7A	wingless-type MMTV integration site family, member 7A	0.015
HOXB13	homeobox B13	0.015
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.015
BIN1	bridging integrator 1	0.015
CLU	clusterin	0.015
BHLHE23	basic helix-loop-helix family, member e23	0.015
NCOA6	nuclear receptor coactivator 6	0.015
MAX	MYC associated factor X	0.015
GATA2	GATA binding protein 2	0.015
HOXA6	homeobox A6	0.015
USP42	ubiquitin specific peptidase 42	0.015
HOXA2	homeobox A2	0.015
NKX6-2	NK6 homeobox 2	0.014
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.014
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.014
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.014
SMAD4	SMAD family member 4	0.014
MYOD1	myogenic differentiation 1	0.014
HOXA13	homeobox A13	0.014
CAV1	caveolin 1, caveolae protein, 22kDa	0.014
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.014
JUN	jun proto-oncogene	0.014
NEUROG1	neurogenin 1	0.014
HNF4A	hepatocyte nuclear factor 4, alpha	0.014
UVRAG	UV radiation resistance associated gene	0.014
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.014
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.014
DIO3	deiodinase, iodothyronine, type III	0.014
FGF18	fibroblast growth factor 18	0.013
INHBB	inhibin, beta B	0.013
ALX3	ALX homeobox 3	0.013
IRF3	interferon regulatory factor 3	0.013
PML	promyelocytic leukemia	0.013
EVX1	even-skipped homeobox 1	0.013
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.013
RUNDC3A	RUN domain containing 3A	0.013
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.013
SH3GL1	SH3-domain GRB2-like 1	0.013
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.013	Mouse
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.013
HOXB6	homeobox B6	0.013
CSNK1D	casein kinase 1, delta	0.013
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.013
DLX4	distal-less homeobox 4	0.013
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.013
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.013
MESP1	mesoderm posterior 1 homolog (mouse)	0.012
GSTM4	glutathione S-transferase mu 4	0.012
MYST1	MYST histone acetyltransferase 1	0.012
HOXB3	homeobox B3	0.012
C22orf39	chromosome 22 open reading frame 39	0.012
HOXD12	homeobox D12	0.012	Fly
WNT1	wingless-type MMTV integration site family, member 1	0.012
EFNA2	ephrin-A2	0.012
CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.012
TBX1	T-box 1	0.012
PAX5	paired box 5	0.012
FGFR3	fibroblast growth factor receptor 3	0.012
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.012
FGF3	fibroblast growth factor 3	0.012
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.012
TCF4	transcription factor 4	0.012
FMNL1	formin-like 1	0.012
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.012
MNX1	motor neuron and pancreas homeobox 1	0.012
RCAN1	regulator of calcineurin 1	0.012
SIK2	salt-inducible kinase 2	0.012
PROX1	prospero homeobox 1	0.012
HOXA3	homeobox A3	0.012
ZNF420	zinc finger protein 420	0.012
SETD8	SET domain containing (lysine methyltransferase) 8	0.012
AFTPH	aftiphilin	0.012
LAMA5	laminin, alpha 5	0.012
MAGEA2	melanoma antigen family A, 2	0.012
PYCARD	PYD and CARD domain containing	0.011
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.011
PDZK1	PDZ domain containing 1	0.011
HAND1	heart and neural crest derivatives expressed 1	0.011
LMX1B	LIM homeobox transcription factor 1, beta	0.011
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.011
F3	coagulation factor III (thromboplastin, tissue factor)	0.011
MAP2K5	mitogen-activated protein kinase kinase 5	0.011
HOXD1	homeobox D1	0.011
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.011
POU4F3	POU class 4 homeobox 3	0.011
HOXC13	homeobox C13	0.011
HOXC10	homeobox C10	0.011
PPP2R3B	protein phosphatase 2, regulatory subunit B'', beta	0.011
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.011
NKD2	naked cuticle homolog 2 (Drosophila)	0.011
ZNF219	zinc finger protein 219	0.011
GLIS2	GLIS family zinc finger 2	0.011
BCL3	B-cell CLL/lymphoma 3	0.011
B4GALNT2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.011
MAPK3	mitogen-activated protein kinase 3	0.011
GADD45B	growth arrest and DNA-damage-inducible, beta	0.011
FBXW8	F-box and WD repeat domain containing 8	0.011
JUB	jub, ajuba homolog (Xenopus laevis)	0.011
BARX1	BARX homeobox 1	0.011
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011
HOXC11	homeobox C11	0.011
HOXD3	homeobox D3	0.011
BMP4	bone morphogenetic protein 4	0.011
HOXA4	homeobox A4	0.011	Fly
GFRA3	GDNF family receptor alpha 3	0.011
HOXB2	homeobox B2	0.011
HAND2	heart and neural crest derivatives expressed 2	0.011	Mouse
RIPK4	receptor-interacting serine-threonine kinase 4	0.011
CDH16	cadherin 16, KSP-cadherin	0.011
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.011
MT1A	metallothionein 1A	0.011
DSP	desmoplakin	0.011
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.011
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.011
BNC1	basonuclin 1	0.011
HOXA1	homeobox A1	0.011
FZD10	frizzled homolog 10 (Drosophila)	0.011
RUNX3	runt-related transcription factor 3	0.010
EFNA1	ephrin-A1	0.010
OTUD5	OTU domain containing 5	0.010
CUL9	cullin 9	0.010
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.010
FOXD1	forkhead box D1	0.010
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.010
S100A4	S100 calcium binding protein A4	0.010
ONECUT2	one cut homeobox 2	0.010
POU2F2	POU class 2 homeobox 2	0.010
PRDM13	PR domain containing 13	0.010
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.010
HDAC11	histone deacetylase 11	0.010
FOXB1	forkhead box B1	0.010
DLL4	delta-like 4 (Drosophila)	0.010
GSX2	GS homeobox 2	0.010
TWIST1	twist homolog 1 (Drosophila)	0.010
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.010
HOXC9	homeobox C9	0.010
FEV	FEV (ETS oncogene family)	0.010
FAM163B	family with sequence similarity 163, member B	0.010