IMP
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Homo sapiens
21 genes annotated in human
thoracic cancer
DOID:5093
An organ system cancer located in the thoracic cavity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "thoracic cancer"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BRCA1 | breast cancer 1, early onset | 0.999 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.995 | ||
| BRCA2 | breast cancer 2, early onset | 0.973 | ||
| H2AFX | H2A histone family, member X | 0.777 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.647 | ||
| BLM | Bloom syndrome, RecQ helicase-like | 0.621 | ||
| NBN | nibrin | 0.422 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.359 | ||
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.289 | ||
| DMC1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | 0.230 | ||
| RAD51C | RAD51 homolog C (S. cerevisiae) | 0.227 | ||
| FANCA | Fanconi anemia, complementation group A | 0.183 | ||
| RB1 | retinoblastoma 1 | 0.173 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.151 | Human | |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.144 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.143 | ||
| PLK1 | polo-like kinase 1 | 0.136 | ||
| MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 0.132 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.113 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.088 | ||
| BARD1 | BRCA1 associated RING domain 1 | 0.080 | ||
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.079 | ||
| PALB2 | partner and localizer of BRCA2 | 0.078 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.070 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.069 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.063 | ||
| EXO1 | exonuclease 1 | 0.062 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.061 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.060 | ||
| BRAP | BRCA1 associated protein | 0.048 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.047 | ||
| IRS1 | insulin receptor substrate 1 | 0.046 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.044 | ||
| RPA1 | replication protein A1, 70kDa | 0.043 | ||
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.043 | ||
| MORC3 | MORC family CW-type zinc finger 3 | 0.039 | ||
| ATG16L1 | ATG16 autophagy related 16-like 1 (S. cerevisiae) | 0.038 | ||
| E2F1 | E2F transcription factor 1 | 0.034 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.033 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.031 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.031 | ||
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 0.029 | ||
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | 0.027 | ||
| POLQ | polymerase (DNA directed), theta | 0.025 | ||
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.025 | ||
| ACACA | acetyl-CoA carboxylase alpha | 0.025 | ||
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.024 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.024 | ||
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 0.022 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.022 | ||
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.022 | ||
| HBP1 | HMG-box transcription factor 1 | 0.021 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.021 | ||
| FBXO5 | F-box protein 5 | 0.021 | ||
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.020 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.020 | ||
| RAD51AP1 | RAD51 associated protein 1 | 0.019 | ||
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.019 | ||
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.019 | ||
| ULK2 | unc-51-like kinase 2 (C. elegans) | 0.019 | ||
| ERCC6L | excision repair cross-complementing rodent repair deficiency, complementation group 6-like | 0.019 | ||
| ERBB2IP | erbb2 interacting protein | 0.019 | ||
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.018 | ||
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.018 | ||
| SLC38A2 | solute carrier family 38, member 2 | 0.017 | ||
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) | 0.017 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.017 | ||
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.017 | ||
| SIRT1 | sirtuin 1 | 0.016 | ||
| ATG12 | ATG12 autophagy related 12 homolog (S. cerevisiae) | 0.016 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.016 | ||
| KLHL24 | kelch-like 24 (Drosophila) | 0.016 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.016 | ||
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.016 | ||
| FHL2 | four and a half LIM domains 2 | 0.016 | ||
| CCNE1 | cyclin E1 | 0.015 | ||
| PDS5B | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.015 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.015 | ||
| PARN | poly(A)-specific ribonuclease (deadenylation nuclease) | 0.015 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.014 | ||
| IGSF21 | immunoglobin superfamily, member 21 | 0.014 | ||
| TBC1D15 | TBC1 domain family, member 15 | 0.014 | ||
| SYCP3 | synaptonemal complex protein 3 | 0.014 | ||
| FAM175A | family with sequence similarity 175, member A | 0.014 | ||
| MKRN1 | makorin ring finger protein 1 | 0.014 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.014 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.014 | ||
| TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.014 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.013 | ||
| PSEN1 | presenilin 1 | 0.013 | ||
| ZNF350 | zinc finger protein 350 | 0.013 | ||
| OXR1 | oxidation resistance 1 | 0.013 | ||
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.013 | ||
| SGOL1 | shugoshin-like 1 (S. pombe) | 0.013 | ||
| RYBP | RING1 and YY1 binding protein | 0.013 | ||
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.013 | Human | |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.013 | ||
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | 0.013 | ||
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | 0.012 | ||
| GTF2I | general transcription factor IIi | 0.012 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.012 | ||
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.012 | ||
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.012 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.012 | ||
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.012 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.012 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.012 | ||
| AR | androgen receptor | 0.012 | ||
| C15orf42 | chromosome 15 open reading frame 42 | 0.012 | ||
| CLSPN | claspin | 0.011 | ||
| NLRP2 | NLR family, pyrin domain containing 2 | 0.011 | ||
| ATM | ataxia telangiectasia mutated | 0.011 | ||
| CEP55 | centrosomal protein 55kDa | 0.011 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.011 | ||
| PTEN | phosphatase and tensin homolog | 0.011 | ||
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.011 | ||
| UIMC1 | ubiquitin interaction motif containing 1 | 0.011 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.011 | ||
| RECQL4 | RecQ protein-like 4 | 0.011 | ||
| HTT | huntingtin | 0.011 | ||
| WDR26 | WD repeat domain 26 | 0.011 | ||
| AURKA | aurora kinase A | 0.010 | ||
| SPAG9 | sperm associated antigen 9 | 0.010 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.010 | ||
| JUP | junction plakoglobin | 0.010 | ||
| OBFC2B | oligonucleotide/oligosaccharide-binding fold containing 2B | 0.010 | ||
| BRD7 | bromodomain containing 7 | 0.010 | ||
| C5orf41 | chromosome 5 open reading frame 41 | 0.010 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.010 | ||
| TBK1 | TANK-binding kinase 1 | 0.010 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.010 | ||
| CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.010 | ||
| TRIM23 | tripartite motif containing 23 | 0.010 | ||
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.010 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.006 | ||
| RAD54L | RAD54-like (S. cerevisiae) | 0.005 | ||
| SLC22A18 | solute carrier family 22, member 18 | 0.003 | ||
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.003 | ||
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.003 | ||
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.003 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.002 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.002 | ||
| TSG101 | tumor susceptibility gene 101 | 0.001 | ||
| TP53 | tumor protein p53 | 0.001 | ||
| PHB | prohibitin | 0.000 |