IMP

Process View

Homo sapiens

30 genes annotated in human

regulation of blood pressure

Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of blood pressure"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of blood pressure" (in gray)

Name	Description	Probability	Func Analog Organism
C1QA	complement component 1, q subcomponent, A chain	0.963	Human
ENG	endoglin	0.796
SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	0.766	Rat
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.741
SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	0.638	Rat
SULT1A4	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	0.550	Rat
COL1A1	collagen, type I, alpha 1	0.531	Human
TGFB1	transforming growth factor, beta 1	0.511
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.478
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.472	Mouse
FKBP1A	FK506 binding protein 1A, 12kDa	0.468
ADORA2A	adenosine A2a receptor	0.430
COL3A1	collagen, type III, alpha 1	0.394	Human
BMP2	bone morphogenetic protein 2	0.393
HBB	hemoglobin, beta	0.375
AXL	AXL receptor tyrosine kinase	0.354
NOSTRIN	nitric oxide synthase trafficker	0.345
RARA	retinoic acid receptor, alpha	0.313
COL4A1	collagen, type IV, alpha 1	0.264
HNF4A	hepatocyte nuclear factor 4, alpha	0.262
DDR2	discoidin domain receptor tyrosine kinase 2	0.257
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.255
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.203
VAC14	Vac14 homolog (S. cerevisiae)	0.200
THBS1	thrombospondin 1	0.195
PLCG1	phospholipase C, gamma 1	0.186	Human
COL1A2	collagen, type I, alpha 2	0.185
C1QC	complement component 1, q subcomponent, C chain	0.176	Human
CAV2	caveolin 2	0.171
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.167
HBG2	hemoglobin, gamma G	0.162
IL8	interleukin 8	0.159
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.145
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.131
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.128
COL5A2	collagen, type V, alpha 2	0.120	Human
HIPK2	homeodomain interacting protein kinase 2	0.119
NCF1	neutrophil cytosolic factor 1	0.117
SMAD7	SMAD family member 7	0.110
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.109
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.101
C1QB	complement component 1, q subcomponent, B chain	0.101	Human
NCF4	neutrophil cytosolic factor 4, 40kDa	0.094
PRKCA	protein kinase C, alpha	0.092
COL6A1	collagen, type VI, alpha 1	0.091
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.090
NCOR2	nuclear receptor corepressor 2	0.088
CXCL2	chemokine (C-X-C motif) ligand 2	0.088
TGFB3	transforming growth factor, beta 3	0.085
PAX8	paired box 8	0.084
RXRA	retinoid X receptor, alpha	0.084
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.083
ARNT	aryl hydrocarbon receptor nuclear translocator	0.075
CAV1	caveolin 1, caveolae protein, 22kDa	0.073
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.071
COL5A1	collagen, type V, alpha 1	0.070	Human
GDF5	growth differentiation factor 5	0.068
FSTL1	follistatin-like 1	0.062
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.061	Rat
NAMPT	nicotinamide phosphoribosyltransferase	0.058
CYBA	cytochrome b-245, alpha polypeptide	0.058
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.053
GRB2	growth factor receptor-bound protein 2	0.051
PRKG1	protein kinase, cGMP-dependent, type I	0.048
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.047	Mouse
VEGFA	vascular endothelial growth factor A	0.046
PTEN	phosphatase and tensin homolog	0.045
HR	hairless homolog (mouse)	0.043
BGN	biglycan	0.042
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.039
GRN	granulin	0.039
LAMP2	lysosomal-associated membrane protein 2	0.039
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.038	Mouse
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.038
TIMP3	TIMP metallopeptidase inhibitor 3	0.037
ACVR1	activin A receptor, type I	0.036	Human
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.036
LOX	lysyl oxidase	0.036
CXCL3	chemokine (C-X-C motif) ligand 3	0.035
IGF1	insulin-like growth factor 1 (somatomedin C)	0.034
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.033
ZMYND11	zinc finger, MYND-type containing 11	0.033
COL6A2	collagen, type VI, alpha 2	0.032
SKIL	SKI-like oncogene	0.031
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.031	Human
GAA	glucosidase, alpha; acid	0.031
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.031
SDF2L1	stromal cell-derived factor 2-like 1	0.030
DPYSL4	dihydropyrimidinase-like 4	0.030
GLIS2	GLIS family zinc finger 2	0.030
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.029
STAB1	stabilin 1	0.029
NCOR1	nuclear receptor corepressor 1	0.028
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.028
SH3BP2	SH3-domain binding protein 2	0.028
EDN3	endothelin 3	0.028
COL6A3	collagen, type VI, alpha 3	0.028
BMPR1A	bone morphogenetic protein receptor, type IA	0.026	Human
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.026
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.026
APOE	apolipoprotein E	0.025
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.025
BDKRB2	bradykinin receptor B2	0.025
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.025
NCOA2	nuclear receptor coactivator 2	0.025
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.025
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.025
CHD9	chromodomain helicase DNA binding protein 9	0.024
HBD	hemoglobin, delta	0.024
BMP1	bone morphogenetic protein 1	0.023
TKT	transketolase	0.023
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.023
POSTN	periostin, osteoblast specific factor	0.023
WNK1	WNK lysine deficient protein kinase 1	0.023	Mouse
PRKCDBP	protein kinase C, delta binding protein	0.023
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.023
NID1	nidogen 1	0.022
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.022
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.022
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.022
HDAC4	histone deacetylase 4	0.022
APP	amyloid beta (A4) precursor protein	0.022
DAB1	disabled homolog 1 (Drosophila)	0.022
DUSP6	dual specificity phosphatase 6	0.022
COL18A1	collagen, type XVIII, alpha 1	0.022
CD93	CD93 molecule	0.021
CAPRIN2	caprin family member 2	0.021
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.021
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.021
HSPB1	heat shock 27kDa protein 1	0.020
SH3GL3	SH3-domain GRB2-like 3	0.020
MYH11	myosin, heavy chain 11, smooth muscle	0.020
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.019
COL4A2	collagen, type IV, alpha 2	0.019
ACVRL1	activin A receptor type II-like 1	0.019
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.019
IFNGR1	interferon gamma receptor 1	0.019
PIGR	polymeric immunoglobulin receptor	0.018
GLP1R	glucagon-like peptide 1 receptor	0.018	Rat
GRB10	growth factor receptor-bound protein 10	0.018
IGFBP5	insulin-like growth factor binding protein 5	0.018
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.018	Human
PXDN	peroxidasin homolog (Drosophila)	0.018
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.018
LAMP1	lysosomal-associated membrane protein 1	0.018
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.018	Human
FEV	FEV (ETS oncogene family)	0.018
DCN	decorin	0.018
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.018
NCOA7	nuclear receptor coactivator 7	0.018
ADAM12	ADAM metallopeptidase domain 12	0.018
RET	ret proto-oncogene	0.018
SRPX	sushi-repeat containing protein, X-linked	0.018
IL1B	interleukin 1, beta	0.018
DLG4	discs, large homolog 4 (Drosophila)	0.017
HEXB	hexosaminidase B (beta polypeptide)	0.017
LGALS1	lectin, galactoside-binding, soluble, 1	0.017
IGFBP3	insulin-like growth factor binding protein 3	0.017
GABRQ	gamma-aminobutyric acid (GABA) receptor, theta	0.017
TAC1	tachykinin, precursor 1	0.017	Rat
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.017
BIRC3	baculoviral IAP repeat containing 3	0.017
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.017
COL2A1	collagen, type II, alpha 1	0.017	Human
MUC1	mucin 1, cell surface associated	0.017
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.017
HYOU1	hypoxia up-regulated 1	0.017
GNS	glucosamine (N-acetyl)-6-sulfatase	0.017
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.017
PLG	plasminogen	0.017
AVPR2	arginine vasopressin receptor 2	0.016	Rat
AMN	amnionless homolog (mouse)	0.016
FKBP10	FK506 binding protein 10, 65 kDa	0.016
HBA2	hemoglobin, alpha 2	0.016	Rat
UNC5B	unc-5 homolog B (C. elegans)	0.016
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.016
HPN	hepsin	0.016	Human
BBS1	Bardet-Biedl syndrome 1	0.016
ANGPT1	angiopoietin 1	0.016
EDNRA	endothelin receptor type A	0.016
NCOA6	nuclear receptor coactivator 6	0.016
TACR1	tachykinin receptor 1	0.016	Rat
RRAS	related RAS viral (r-ras) oncogene homolog	0.015
VWF	von Willebrand factor	0.015
IL6	interleukin 6 (interferon, beta 2)	0.015
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.015	Human
LRRK2	leucine-rich repeat kinase 2	0.015
PTK6	PTK6 protein tyrosine kinase 6	0.015
COL14A1	collagen, type XIV, alpha 1	0.015
COL11A1	collagen, type XI, alpha 1	0.015	Human
HBE1	hemoglobin, epsilon 1	0.014
HTRA1	HtrA serine peptidase 1	0.014
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.014
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.014
MAPT	microtubule-associated protein tau	0.014
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.014
TSPAN4	tetraspanin 4	0.014
SAT1	spermidine/spermine N1-acetyltransferase 1	0.014
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.014
C1QTNF1	C1q and tumor necrosis factor related protein 1	0.014	Human
RIPK2	receptor-interacting serine-threonine kinase 2	0.014
FGFR1	fibroblast growth factor receptor 1	0.014
CAB39	calcium binding protein 39	0.014
IRS1	insulin receptor substrate 1	0.014
NPC2	Niemann-Pick disease, type C2	0.014
GAS6	growth arrest-specific 6	0.014	Rat
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.014
WNT3A	wingless-type MMTV integration site family, member 3A	0.014
MBL2	mannose-binding lectin (protein C) 2, soluble	0.014
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.014
COL15A1	collagen, type XV, alpha 1	0.014
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.014
MXRA5	matrix-remodelling associated 5	0.013
KLK2	kallikrein-related peptidase 2	0.013
FAP	fibroblast activation protein, alpha	0.013
BMP4	bone morphogenetic protein 4	0.013
CALCRL	calcitonin receptor-like	0.013
FNDC1	fibronectin type III domain containing 1	0.013
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.013
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.013
MAG	myelin associated glycoprotein	0.013
LRRN2	leucine rich repeat neuronal 2	0.013
PDGFA	platelet-derived growth factor alpha polypeptide	0.013
TUBB8	tubulin, beta 8	0.013
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.013
CCL20	chemokine (C-C motif) ligand 20	0.013
CD68	CD68 molecule	0.013
NCOA1	nuclear receptor coactivator 1	0.013
LTBP1	latent transforming growth factor beta binding protein 1	0.013
PSAP	prosaposin	0.013
CHRNB4	cholinergic receptor, nicotinic, beta 4	0.013
LHB	luteinizing hormone beta polypeptide	0.013
ANGPTL2	angiopoietin-like 2	0.013
NAGA	N-acetylgalactosaminidase, alpha-	0.013
TGFBR3	transforming growth factor, beta receptor III	0.012	Human
PTPRN	protein tyrosine phosphatase, receptor type, N	0.012
NID2	nidogen 2 (osteonidogen)	0.012
PTRF	polymerase I and transcript release factor	0.012
PRLR	prolactin receptor	0.012
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.012	Mouse Rat
ESRRG	estrogen-related receptor gamma	0.012
CST3	cystatin C	0.012
TBXA2R	thromboxane A2 receptor	0.012
FOXN1	forkhead box N1	0.012
CRHBP	corticotropin releasing hormone binding protein	0.012
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.012
PRKCD	protein kinase C, delta	0.012
TFPI2	tissue factor pathway inhibitor 2	0.012
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.012
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.012
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.012
A2M	alpha-2-macroglobulin	0.012
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.012
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.012
NCR2	natural cytotoxicity triggering receptor 2	0.012
PLAUR	plasminogen activator, urokinase receptor	0.012
T	T, brachyury homolog (mouse)	0.012
RECK	reversion-inducing-cysteine-rich protein with kazal motifs	0.012
NPTN	neuroplastin	0.012
OLFML2B	olfactomedin-like 2B	0.012
DOK4	docking protein 4	0.012
ALPL	alkaline phosphatase, liver/bone/kidney	0.012
CXCL12	chemokine (C-X-C motif) ligand 12	0.012
COL8A2	collagen, type VIII, alpha 2	0.011
KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.011
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.011
VAV2	vav 2 guanine nucleotide exchange factor	0.011
SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2	0.011
GPR6	G protein-coupled receptor 6	0.011
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.011
CRELD2	cysteine-rich with EGF-like domains 2	0.011
WNT2	wingless-type MMTV integration site family member 2	0.011
TPM2	tropomyosin 2 (beta)	0.011
CLPS	colipase, pancreatic	0.011
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.011
LAMA2	laminin, alpha 2	0.011
DSCAML1	Down syndrome cell adhesion molecule like 1	0.011
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.011
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.011
PLD3	phospholipase D family, member 3	0.011
C8B	complement component 8, beta polypeptide	0.011
PROCR	protein C receptor, endothelial	0.011
EFNB1	ephrin-B1	0.011
MUC4	mucin 4, cell surface associated	0.011
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.011
PPARA	peroxisome proliferator-activated receptor alpha	0.011	Human Rat
PTPRF	protein tyrosine phosphatase, receptor type, F	0.011
POU2F2	POU class 2 homeobox 2	0.011
COL4A6	collagen, type IV, alpha 6	0.011
IHH	Indian hedgehog	0.011
AHR	aryl hydrocarbon receptor	0.011	Mouse
CXCL5	chemokine (C-X-C motif) ligand 5	0.011
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.011
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.011
NNT	nicotinamide nucleotide transhydrogenase	0.011
DUSP1	dual specificity phosphatase 1	0.011
CD248	CD248 molecule, endosialin	0.011
CDX1	caudal type homeobox 1	0.011
OSTC	oligosaccharyltransferase complex subunit	0.011
PRKCE	protein kinase C, epsilon	0.011
EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	0.011
GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)	0.011
OLFML3	olfactomedin-like 3	0.011
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.011
SH2B1	SH2B adaptor protein 1	0.011
NRP1	neuropilin 1	0.011
CTSA	cathepsin A	0.011
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.011
SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	0.011
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.011
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
EDNRB	endothelin receptor type B	0.011	Mouse Rat
RAX	retina and anterior neural fold homeobox	0.011
AQP7	aquaporin 7	0.011
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.010
NKX3-1	NK3 homeobox 1	0.010
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.010
TRIM15	tripartite motif containing 15	0.010
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.010
C5AR1	complement component 5a receptor 1	0.010
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.010	Human
FOLH1	folate hydrolase (prostate-specific membrane antigen) 1	0.010
AXIN1	axin 1	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010
SSTR1	somatostatin receptor 1	0.010
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.010	Human
THBD	thrombomodulin	0.010
CAPG	capping protein (actin filament), gelsolin-like	0.010
TM4SF5	transmembrane 4 L six family member 5	0.010
TPO	thyroid peroxidase	0.010
LAMB1	laminin, beta 1	0.010
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.010
CLCNKB	chloride channel Kb	0.010
PTX3	pentraxin 3, long	0.010
APOC1	apolipoprotein C-I	0.010
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.010
SCARB2	scavenger receptor class B, member 2	0.010
NOS1	nitric oxide synthase 1 (neuronal)	0.010	Human Rat
INHBA	inhibin, beta A	0.010
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.010
TH	tyrosine hydroxylase	0.010
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.010