IMP

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Homo sapiens

25 genes annotated in human

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t cell mediated immunity

GO:0002456

Any process involved in the carrying out of an immune response by a T cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell mediated immunity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "t cell mediated immunity" (in gray)

Name	Description	Probability	Func Analog Organism
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.959
B2M	beta-2-microglobulin	0.932	Mouse
HLA-B	major histocompatibility complex, class I, B	0.818
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.813
HLA-A	major histocompatibility complex, class I, A	0.791
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.605
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.586
HLA-G	major histocompatibility complex, class I, G	0.555	Human
BTN3A2	butyrophilin, subfamily 3, member A2	0.538
BTN3A3	butyrophilin, subfamily 3, member A3	0.449
HLA-F	major histocompatibility complex, class I, F	0.441	Human
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.425
IL4R	interleukin 4 receptor	0.424
HLA-C	major histocompatibility complex, class I, C	0.417	Human
CCL5	chemokine (C-C motif) ligand 5	0.417	Human
BTN3A1	butyrophilin, subfamily 3, member A1	0.401	Human
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.390
BIRC3	baculoviral IAP repeat containing 3	0.341
CD40	CD40 molecule, TNF receptor superfamily member 5	0.333
NOTCH3	notch 3	0.284
CXCL9	chemokine (C-X-C motif) ligand 9	0.246
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.237	Human
CCR5	chemokine (C-C motif) receptor 5	0.212
NOTCH1	notch 1	0.210
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.183
IL2RG	interleukin 2 receptor, gamma	0.179
CD80	CD80 molecule	0.170
SIGLEC7	sialic acid binding Ig-like lectin 7	0.167
SRGN	serglycin	0.167
HLA-E	major histocompatibility complex, class I, E	0.166	Human
PILRA	paired immunoglobin-like type 2 receptor alpha	0.161
CXCL10	chemokine (C-X-C motif) ligand 10	0.159
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.157
CCL8	chemokine (C-C motif) ligand 8	0.144	Human
TRAF1	TNF receptor-associated factor 1	0.132	Human
TAPBP	TAP binding protein (tapasin)	0.130
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.113	Human
SNAP23	synaptosomal-associated protein, 23kDa	0.109
CCR1	chemokine (C-C motif) receptor 1	0.100
CXCL11	chemokine (C-X-C motif) ligand 11	0.088
CCL4	chemokine (C-C motif) ligand 4	0.076	Human
CCR7	chemokine (C-C motif) receptor 7	0.074
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.070
CCL13	chemokine (C-C motif) ligand 13	0.067	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.061	Human
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.057
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.056
TNF	tumor necrosis factor	0.055
SQSTM1	sequestosome 1	0.053
TRIM38	tripartite motif containing 38	0.051
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.050
ICAM1	intercellular adhesion molecule 1	0.048	Mouse
BTN2A2	butyrophilin, subfamily 2, member A2	0.048	Human
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.046
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.043
NOTCH2	notch 2	0.041
IL10	interleukin 10	0.041
IL10RA	interleukin 10 receptor, alpha	0.040
GFI1B	growth factor independent 1B transcription repressor	0.039
CCL11	chemokine (C-C motif) ligand 11	0.039	Human
VAMP4	vesicle-associated membrane protein 4	0.038
TGIF1	TGFB-induced factor homeobox 1	0.038
IL1B	interleukin 1, beta	0.036
IFNG	interferon, gamma	0.035
ADAM17	ADAM metallopeptidase domain 17	0.035
IL8	interleukin 8	0.034
LGALS3	lectin, galactoside-binding, soluble, 3	0.034
IDE	insulin-degrading enzyme	0.033
CD163	CD163 molecule	0.033
CCL2	chemokine (C-C motif) ligand 2	0.033	Human
ZMYND11	zinc finger, MYND-type containing 11	0.032
TRAF2	TNF receptor-associated factor 2	0.032
TYMP	thymidine phosphorylase	0.031
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.031
CCL22	chemokine (C-C motif) ligand 22	0.031	Human
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.030
OASL	2'-5'-oligoadenylate synthetase-like	0.030
IL15RA	interleukin 15 receptor, alpha	0.030
PML	promyelocytic leukemia	0.030
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.029
CCL7	chemokine (C-C motif) ligand 7	0.029	Human
PTAFR	platelet-activating factor receptor	0.028
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.027	Human
DPP4	dipeptidyl-peptidase 4	0.027
TRADD	TNFRSF1A-associated via death domain	0.027
BTN2A1	butyrophilin, subfamily 2, member A1	0.027	Human
CD48	CD48 molecule	0.026
CD247	CD247 molecule	0.026
TJP1	tight junction protein 1 (zona occludens 1)	0.025
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.025
HK3	hexokinase 3 (white cell)	0.025
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.025
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.024
FPR3	formyl peptide receptor 3	0.024
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.023
CALCOCO2	calcium binding and coiled-coil domain 2	0.023
CXCL13	chemokine (C-X-C motif) ligand 13	0.023
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.023
NLRP3	NLR family, pyrin domain containing 3	0.023
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.022
PBK	PDZ binding kinase	0.022
FAS	Fas (TNF receptor superfamily, member 6)	0.022
TFRC	transferrin receptor (p90, CD71)	0.022
IL2RB	interleukin 2 receptor, beta	0.021
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.021
PLEK	pleckstrin	0.021
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.021
HCP5	HLA complex P5	0.020
CD22	CD22 molecule	0.020
TRAF6	TNF receptor-associated factor 6	0.019
FASLG	Fas ligand (TNF superfamily, member 6)	0.019
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.018
IL6	interleukin 6 (interferon, beta 2)	0.018
BCL10	B-cell CLL/lymphoma 10	0.018
CD83	CD83 molecule	0.018
IL1RN	interleukin 1 receptor antagonist	0.017
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.017
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.017
UBD	ubiquitin D	0.017
EPHB3	EPH receptor B3	0.017
CD33	CD33 molecule	0.017
IL32	interleukin 32	0.017
NSF	N-ethylmaleimide-sensitive factor	0.016
CCR4	chemokine (C-C motif) receptor 4	0.016
APOL1	apolipoprotein L, 1	0.016
LAMP3	lysosomal-associated membrane protein 3	0.016
LGALS9	lectin, galactoside-binding, soluble, 9	0.016	Human
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.016
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.016	Human
ZBP1	Z-DNA binding protein 1	0.015
IL2RA	interleukin 2 receptor, alpha	0.015
TREM1	triggering receptor expressed on myeloid cells 1	0.015
CCR3	chemokine (C-C motif) receptor 3	0.015
LCK	lymphocyte-specific protein tyrosine kinase	0.015
SLAMF8	SLAM family member 8	0.015
LMO2	LIM domain only 2 (rhombotin-like 1)	0.015
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.014
KRTAP4-12	keratin associated protein 4-12	0.014
NUMBL	numb homolog (Drosophila)-like	0.014
VCAM1	vascular cell adhesion molecule 1	0.014
CSF1	colony stimulating factor 1 (macrophage)	0.014
GRPEL1	GrpE-like 1, mitochondrial (E. coli)	0.014
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.014
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.014
RUNX3	runt-related transcription factor 3	0.014
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.014
STX6	syntaxin 6	0.013
IL4	interleukin 4	0.013
ADAMDEC1	ADAM-like, decysin 1	0.013
IDO1	indoleamine 2,3-dioxygenase 1	0.013
IL13	interleukin 13	0.013	Human
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.013
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.013	Human
CLEC10A	C-type lectin domain family 10, member A	0.013
SH2D2A	SH2 domain containing 2A	0.013
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.012
EBI3	Epstein-Barr virus induced 3	0.012
CD2	CD2 molecule	0.012
HFE	hemochromatosis	0.012	Human
IL18RAP	interleukin 18 receptor accessory protein	0.012
NLRC5	NLR family, CARD domain containing 5	0.012
CA12	carbonic anhydrase XII	0.012
C1QB	complement component 1, q subcomponent, B chain	0.012
C3AR1	complement component 3a receptor 1	0.012
APOL3	apolipoprotein L, 3	0.012
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.012
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.012
PECAM1	platelet/endothelial cell adhesion molecule	0.012
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.012	Human
ZNF512B	zinc finger protein 512B	0.012
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.011
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.011	Human
CD209	CD209 molecule	0.011
PRF1	perforin 1 (pore forming protein)	0.011
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
IRF1	interferon regulatory factor 1	0.011
AOAH	acyloxyacyl hydrolase (neutrophil)	0.011
HCK	hemopoietic cell kinase	0.011
IL7	interleukin 7	0.011
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.011
TBX21	T-box 21	0.011
MBD4	methyl-CpG binding domain protein 4	0.011
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.010
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.010
CTSS	cathepsin S	0.010
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.010
CARD11	caspase recruitment domain family, member 11	0.010