IMP

Process View

Mus musculus

3 genes annotated in mouse

regulation of interleukin 4 biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 4 biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 4 biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Cd80	CD80 antigen	0.991
Pdcd1	programmed cell death 1	0.892
Icos	inducible T-cell co-stimulator	0.875
Batf	basic leucine zipper transcription factor, ATF-like	0.542
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.532
Cxcl9	chemokine (C-X-C motif) ligand 9	0.274
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.235
Zbp1	Z-DNA binding protein 1	0.227
Cd40	CD40 antigen	0.200
Ccl4	chemokine (C-C motif) ligand 4	0.199
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.165
Rel	reticuloendotheliosis oncogene	0.155
Ifng	interferon gamma	0.149
Igh	immunoglobulin heavy chain complex	0.115
Tbx21	T-box 21	0.109
Il4	interleukin 4	0.102
Rhoh	ras homolog gene family, member H	0.100
Il2ra	interleukin 2 receptor, alpha chain	0.096
Slamf7	SLAM family member 7	0.091
Ccr7	chemokine (C-C motif) receptor 7	0.091
Cd5	CD5 antigen	0.086
Irf8	interferon regulatory factor 8	0.080
Gata1	GATA binding protein 1	0.079
Slamf1	signaling lymphocytic activation molecule family member 1	0.073
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.066
Il21r	interleukin 21 receptor	0.064
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.064
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.063
Naip6	NLR family, apoptosis inhibitory protein 6	0.059
Il10ra	interleukin 10 receptor, alpha	0.057
Ubd	ubiquitin D	0.057
Gpr33	G protein-coupled receptor 33	0.052
Gbp1	guanylate binding protein 1	0.050
Slamf8	SLAM family member 8	0.050
Plek	pleckstrin	0.049
Cd274	CD274 antigen	0.049	Mouse
Il12rb1	interleukin 12 receptor, beta 1	0.048
Itga4	integrin alpha 4	0.045
Cd160	CD160 antigen	0.042
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.041
Bcl6	B-cell leukemia/lymphoma 6	0.041
Btk	Bruton agammaglobulinemia tyrosine kinase	0.041
Mta1	metastasis associated 1	0.040
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.040
Gbp7	guanylate binding protein 7	0.039
Pou2af1	POU domain, class 2, associating factor 1	0.039
Rgs1	regulator of G-protein signaling 1	0.039
Lta	lymphotoxin A	0.038
Cd6	CD6 antigen	0.038
Oas3	2'-5' oligoadenylate synthetase 3	0.036
Mx1	myxovirus (influenza virus) resistance 1	0.035
Il1r2	interleukin 1 receptor, type II	0.034
Lag3	lymphocyte-activation gene 3	0.034
Fasl	Fas ligand (TNF superfamily, member 6)	0.034
Bmp1	bone morphogenetic protein 1	0.033
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.033
Irg1	immunoresponsive gene 1	0.032
Cd19	CD19 antigen	0.032
Xcl1	chemokine (C motif) ligand 1	0.032
Mta2	metastasis-associated gene family, member 2	0.032
Il27ra	interleukin 27 receptor, alpha	0.031
Gcet2	germinal center expressed transcript 2	0.031
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.031
Traf1	TNF receptor-associated factor 1	0.030
Cxcr6	chemokine (C-X-C motif) receptor 6	0.030
Cd180	CD180 antigen	0.029
Git1	G protein-coupled receptor kinase-interactor 1	0.029
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.029
Cd8a	CD8 antigen, alpha chain	0.029
Mobp	myelin-associated oligodendrocytic basic protein	0.028
Irf5	interferon regulatory factor 5	0.028
Ikzf3	IKAROS family zinc finger 3	0.027
Cd72	CD72 antigen	0.026
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.026
Sp110	Sp110 nuclear body protein	0.026
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.026
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.026
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.026
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.025
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.025
Carm1	coactivator-associated arginine methyltransferase 1	0.025
Ccr9	chemokine (C-C motif) receptor 9	0.025
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.024
Cnga3	cyclic nucleotide gated channel alpha 3	0.024
Ccl3	chemokine (C-C motif) ligand 3	0.024
Itgal	integrin alpha L	0.024
Il2rb	interleukin 2 receptor, beta chain	0.024
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.024
Gbp6	guanylate binding protein 6	0.024
Mcoln2	mucolipin 2	0.023
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.023
Socs1	suppressor of cytokine signaling 1	0.023
Tlr7	toll-like receptor 7	0.022
Cd28	CD28 antigen	0.022
Myo1g	myosin IG	0.021
Trim30d	tripartite motif-containing 30D	0.021
Cd83	CD83 antigen	0.021
Pla2g2d	phospholipase A2, group IID	0.021
Itk	IL2-inducible T-cell kinase	0.020
Trim21	tripartite motif-containing 21	0.019
Lcp2	lymphocyte cytosolic protein 2	0.019
Dnase1l3	deoxyribonuclease 1-like 3	0.019
Tnf	tumor necrosis factor	0.019
Lpxn	leupaxin	0.019
Cd22	CD22 antigen	0.019
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.019
Gzmb	granzyme B	0.018
Cdx1	caudal type homeobox 1	0.017
Parp14	poly (ADP-ribose) polymerase family, member 14	0.017
Cxcl10	chemokine (C-X-C motif) ligand 10	0.017
Cd84	CD84 antigen	0.017
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.017
Traf2	TNF receptor-associated factor 2	0.017
Gbp3	guanylate binding protein 3	0.016
Rc3h1	RING CCCH (C3H) domains 1	0.016
Epsti1	epithelial stromal interaction 1 (breast)	0.016
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.016
Aicda	activation-induced cytidine deaminase	0.016
Ciita	class II transactivator	0.016
Blnk	B-cell linker	0.016
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.016
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.016
Gm6377	predicted gene 6377	0.015
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.015
Gimap7	GTPase, IMAP family member 7	0.015
Cd3e	CD3 antigen, epsilon polypeptide	0.015
Tal1	T-cell acute lymphocytic leukemia 1	0.015
Clnk	cytokine-dependent hematopoietic cell linker	0.015
Khdc1a	KH domain containing 1A	0.015
Bglap	bone gamma carboxyglutamate protein	0.015
Runx3	runt related transcription factor 3	0.015
Ccl24	chemokine (C-C motif) ligand 24	0.015
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.015
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.015
Gm12597	predicted gene 12597	0.015
Siae	sialic acid acetylesterase	0.015
Sh2d1a	SH2 domain protein 1A	0.015
Il23a	interleukin 23, alpha subunit p19	0.015
Ccrl2	chemokine (C-C motif) receptor-like 2	0.015
Sh2d2a	SH2 domain protein 2A	0.014
Card11	caspase recruitment domain family, member 11	0.014
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.014
Tph1	tryptophan hydroxylase 1	0.014
Pyhin1	pyrin and HIN domain family, member 1	0.014
Hpgds	hematopoietic prostaglandin D synthase	0.014
Cxcl2	chemokine (C-X-C motif) ligand 2	0.014
Ncor2	nuclear receptor co-repressor 2	0.014
AW112010	expressed sequence AW112010	0.014
Rag2	recombination activating gene 2	0.014
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.014
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.014
Cd4	CD4 antigen	0.014
Cybb	cytochrome b-245, beta polypeptide	0.014
Iigp1	interferon inducible GTPase 1	0.013
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.013
Scn10a	sodium channel, voltage-gated, type X, alpha	0.013
Prnp	prion protein	0.013
Cd79b	CD79B antigen	0.013
Nod2	nucleotide-binding oligomerization domain containing 2	0.013
Tmprss3	transmembrane protease, serine 3	0.013
Cd7	CD7 antigen	0.013
Sla2	Src-like-adaptor 2	0.013
Slamf6	SLAM family member 6	0.013
Gzmc	granzyme C	0.013
Marco	macrophage receptor with collagenous structure	0.013
Blk	B lymphoid kinase	0.013
Hsh2d	hematopoietic SH2 domain containing	0.013
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.013
Ifi203	interferon activated gene 203	0.013
Il22	interleukin 22	0.013
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.012
Ifi44	interferon-induced protein 44	0.012
Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	0.012
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.012
Cst7	cystatin F (leukocystatin)	0.012
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.012
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.012
Vav1	vav 1 oncogene	0.012
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.012
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.012
Il1rn	interleukin 1 receptor antagonist	0.012
Ccl5	chemokine (C-C motif) ligand 5	0.012
Obp1a	odorant binding protein Ia	0.012
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.012
Ltb	lymphotoxin B	0.012
Sfpi1	SFFV proviral integration 1	0.012
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.012
Il12b	interleukin 12b	0.011
Tapbpl	TAP binding protein-like	0.011
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.011
Plcg2	phospholipase C, gamma 2	0.011
Gpr34	G protein-coupled receptor 34	0.011
Epn1	epsin 1	0.011
Ebi3	Epstein-Barr virus induced gene 3	0.011
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.011
H2-Q6	histocompatibility 2, Q region locus 6	0.011
Pim1	proviral integration site 1	0.011
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.011
Msr1	macrophage scavenger receptor 1	0.011
Psg18	pregnancy specific glycoprotein 18	0.011
Nkg7	natural killer cell group 7 sequence	0.011
BC147527	cDNA sequence BC147527	0.011
Ccl1	chemokine (C-C motif) ligand 1	0.011
Stat4	signal transducer and activator of transcription 4	0.011
P2ry10	purinergic receptor P2Y, G-protein coupled 10	0.011
Clec4e	C-type lectin domain family 4, member e	0.011
Ly9	lymphocyte antigen 9	0.011
Fpr2	formyl peptide receptor 2	0.011
H2-Eb1	histocompatibility 2, class II antigen E beta	0.011
Fgf3	fibroblast growth factor 3	0.010
Rtp4	receptor transporter protein 4	0.010
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.010
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.010
Cytip	cytohesin 1 interacting protein	0.010
Scin	scinderin	0.010
Chrna9	cholinergic receptor, nicotinic, alpha polypeptide 9	0.010
H2-M3	histocompatibility 2, M region locus 3	0.010
Dmp1	dentin matrix protein 1	0.010
Bfsp2	beaded filament structural protein 2, phakinin	0.010
Gfi1	growth factor independent 1	0.010
Tpbpb	trophoblast specific protein beta	0.010