IMP

Process View

Mus musculus

9 genes annotated in mouse

Multi-species View

positive regulation of type 2 immune response

GO:0002830

Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of type 2 immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of type 2 immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl2	chemokine (C-C motif) ligand 2	0.985
Ccl7	chemokine (C-C motif) ligand 7	0.950	Mouse
Ccl8	chemokine (C-C motif) ligand 8	0.865
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.774	Mouse
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.770	Mouse
Ccl4	chemokine (C-C motif) ligand 4	0.753	Mouse
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.741
Il1b	interleukin 1 beta	0.663
Cxcl2	chemokine (C-X-C motif) ligand 2	0.592
Ccr1	chemokine (C-C motif) receptor 1	0.544
H2-Eb1	histocompatibility 2, class II antigen E beta	0.504
Ccl3	chemokine (C-C motif) ligand 3	0.504	Mouse
Saa3	serum amyloid A 3	0.417
Stat6	signal transducer and activator of transcription 6	0.409
Tnf	tumor necrosis factor	0.401
Mmp12	matrix metallopeptidase 12	0.388
Ccl12	chemokine (C-C motif) ligand 12	0.350	Mouse
Ccr2	chemokine (C-C motif) receptor 2	0.318
Fas	Fas (TNF receptor superfamily member 6)	0.317
Ch25h	cholesterol 25-hydroxylase	0.306
Il1rn	interleukin 1 receptor antagonist	0.277
C3ar1	complement component 3a receptor 1	0.267
Cxcl1	chemokine (C-X-C motif) ligand 1	0.263
Ccl22	chemokine (C-C motif) ligand 22	0.252
Ifng	interferon gamma	0.251
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.246
Mx2	myxovirus (influenza virus) resistance 2	0.242
Clec4d	C-type lectin domain family 4, member d	0.235
Cd40	CD40 antigen	0.228
Selp	selectin, platelet	0.227
Cd28	CD28 antigen	0.226
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.225
Irg1	immunoresponsive gene 1	0.215
Msr1	macrophage scavenger receptor 1	0.198
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.196
Cd14	CD14 antigen	0.196
Ccl17	chemokine (C-C motif) ligand 17	0.194	Mouse
Ccl9	chemokine (C-C motif) ligand 9	0.191	Mouse
Il1rl1	interleukin 1 receptor-like 1	0.190
Ptgs2	prostaglandin-endoperoxide synthase 2	0.183
Cxcl9	chemokine (C-X-C motif) ligand 9	0.180
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.169
Itgax	integrin alpha X	0.142
Il6	interleukin 6	0.141
Gzma	granzyme A	0.138
Batf	basic leucine zipper transcription factor, ATF-like	0.133
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.129
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.125
Akt1	thymoma viral proto-oncogene 1	0.111	Mouse
Gzmb	granzyme B	0.110
Il1r1	interleukin 1 receptor, type I	0.105
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.101
Fcgr1	Fc receptor, IgG, high affinity I	0.094
Il10	interleukin 10	0.091
Socs1	suppressor of cytokine signaling 1	0.088
Vhl	von Hippel-Lindau tumor suppressor	0.084
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.081
Mmp3	matrix metallopeptidase 3	0.078
Cxcl10	chemokine (C-X-C motif) ligand 10	0.078
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.078
Cxcl13	chemokine (C-X-C motif) ligand 13	0.078
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.077
Ccl6	chemokine (C-C motif) ligand 6	0.077	Mouse
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.074
Folr2	folate receptor 2 (fetal)	0.070
Lyz2	lysozyme 2	0.069
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.066
Clec4e	C-type lectin domain family 4, member e	0.061
Ubd	ubiquitin D	0.059
Il1r2	interleukin 1 receptor, type II	0.058
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.057
Fasl	Fas ligand (TNF superfamily, member 6)	0.053
Bcl2	B-cell leukemia/lymphoma 2	0.052
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.052
Bcl3	B-cell leukemia/lymphoma 3	0.050
Ldb3	LIM domain binding 3	0.049
Icos	inducible T-cell co-stimulator	0.044
H2-DMa	histocompatibility 2, class II, locus DMa	0.042
Ccr5	chemokine (C-C motif) receptor 5	0.040
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.040
Ctsw	cathepsin W	0.040
Xcl1	chemokine (C motif) ligand 1	0.039
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.038
Cd7	CD7 antigen	0.037
Mmp13	matrix metallopeptidase 13	0.036
Lag3	lymphocyte-activation gene 3	0.036
Cd86	CD86 antigen	0.035
Ccr7	chemokine (C-C motif) receptor 7	0.034
Osmr	oncostatin M receptor	0.033
Ccl11	chemokine (C-C motif) ligand 11	0.033	Mouse
Sele	selectin, endothelial cell	0.033
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.033
Il18rap	interleukin 18 receptor accessory protein	0.033
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.032
Cxcl5	chemokine (C-X-C motif) ligand 5	0.032
Lta	lymphotoxin A	0.032
Lcn2	lipocalin 2	0.031
Slpi	secretory leukocyte peptidase inhibitor	0.031
Il2rb	interleukin 2 receptor, beta chain	0.031
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.030
Vegfa	vascular endothelial growth factor A	0.030
Il1a	interleukin 1 alpha	0.029
Ptges	prostaglandin E synthase	0.029
Ilk	integrin linked kinase	0.028
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.028
Sh2d2a	SH2 domain protein 2A	0.027
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.027
AI607873	expressed sequence AI607873	0.027
Mpeg1	macrophage expressed gene 1	0.027
Timp1	tissue inhibitor of metalloproteinase 1	0.026
Gnao1	guanine nucleotide binding protein, alpha O	0.025
Gm11428	predicted gene 11428	0.025
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.025
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.025
Has1	hyaluronan synthase1	0.024
Csf3	colony stimulating factor 3 (granulocyte)	0.024
Irf7	interferon regulatory factor 7	0.023
Ccrl2	chemokine (C-C motif) receptor-like 2	0.023
Chi3l3	chitinase 3-like 3	0.023
Tlr7	toll-like receptor 7	0.023
Capn1	calpain 1	0.023
Il18r1	interleukin 18 receptor 1	0.022
Slfn4	schlafen 4	0.022
Il10ra	interleukin 10 receptor, alpha	0.022
Cd3e	CD3 antigen, epsilon polypeptide	0.022
Actn2	actinin alpha 2	0.022
Plaur	plasminogen activator, urokinase receptor	0.022
Aoah	acyloxyacyl hydrolase	0.022
Nos2	nitric oxide synthase 2, inducible	0.021
Cxcl16	chemokine (C-X-C motif) ligand 16	0.021
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.020
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.020
Gzmc	granzyme C	0.020
Rarb	retinoic acid receptor, beta	0.020
Rel	reticuloendotheliosis oncogene	0.020
Adora2b	adenosine A2b receptor	0.020
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.019
Expi	extracellular proteinase inhibitor	0.019
C2	complement component 2 (within H-2S)	0.019
Stat3	signal transducer and activator of transcription 3	0.019
Icam1	intercellular adhesion molecule 1	0.018
Rgs1	regulator of G-protein signaling 1	0.018
Retnla	resistin like alpha	0.018
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.018
Akt2	thymoma viral proto-oncogene 2	0.018	Mouse
Clec4n	C-type lectin domain family 4, member n	0.018
Socs3	suppressor of cytokine signaling 3	0.018
Cfb	complement factor B	0.018
Jph3	junctophilin 3	0.017
Prkce	protein kinase C, epsilon	0.017
Il4	interleukin 4	0.017
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.017
Spp1	secreted phosphoprotein 1	0.017
C3	complement component 3	0.017
Rgs16	regulator of G-protein signaling 16	0.017
Il6st	interleukin 6 signal transducer	0.017
Niacr1	niacin receptor 1	0.017
C5ar1	complement component 5a receptor 1	0.017
Col4a3	collagen, type IV, alpha 3	0.017
Mmp10	matrix metallopeptidase 10	0.016
Lep	leptin	0.016
Ccl5	chemokine (C-C motif) ligand 5	0.016	Mouse
Traf1	TNF receptor-associated factor 1	0.016
Pparg	peroxisome proliferator activated receptor gamma	0.016
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.016
Zfp36	zinc finger protein 36	0.016
Hp	haptoglobin	0.016
Scrg1	scrapie responsive gene 1	0.015
Fosl1	fos-like antigen 1	0.015
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.015
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.015
Cdk14	cyclin-dependent kinase 14	0.015
Fpr2	formyl peptide receptor 2	0.014
AW112010	expressed sequence AW112010	0.014
Itga3	integrin alpha 3	0.014
Tgfbr1	transforming growth factor, beta receptor I	0.014
Cma1	chymase 1, mast cell	0.014
Apod	apolipoprotein D	0.014
Atf3	activating transcription factor 3	0.013
Slamf9	SLAM family member 9	0.013
Sfpi1	SFFV proviral integration 1	0.013
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.013
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.013
Cd96	CD96 antigen	0.013
Rxra	retinoid X receptor alpha	0.013
Tbxas1	thromboxane A synthase 1, platelet	0.013
Adam8	a disintegrin and metallopeptidase domain 8	0.013
Slamf8	SLAM family member 8	0.013
C4b	complement component 4B (Childo blood group)	0.013
Mcpt4	mast cell protease 4	0.013
Irf4	interferon regulatory factor 4	0.013
Mthfs	5, 10-methenyltetrahydrofolate synthetase	0.013
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.012
F10	coagulation factor X	0.012
Gzmk	granzyme K	0.012
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.012
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.012
Hdc	histidine decarboxylase	0.012
Pdcd1lg2	programmed cell death 1 ligand 2	0.012
Areg	amphiregulin	0.012
Btbd10	BTB (POZ) domain containing 10	0.012
Mmp8	matrix metallopeptidase 8	0.012
Plau	plasminogen activator, urokinase	0.012
C1qc	complement component 1, q subcomponent, C chain	0.012
Mapkapk2	MAP kinase-activated protein kinase 2	0.011
Homer1	homer homolog 1 (Drosophila)	0.011
Mapkap1	mitogen-activated protein kinase associated protein 1	0.011
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.011
Bst1	bone marrow stromal cell antigen 1	0.011
Ifitm6	interferon induced transmembrane protein 6	0.011
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.011
Clec7a	C-type lectin domain family 7, member a	0.011
Il7r	interleukin 7 receptor	0.011
Npy2r	neuropeptide Y receptor Y2	0.011
Irf5	interferon regulatory factor 5	0.011
Alox15	arachidonate 15-lipoxygenase	0.011
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.010
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.010
Ncr1	natural cytotoxicity triggering receptor 1	0.010
Mxd1	MAX dimerization protein 1	0.010
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.010