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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of actin filament bundle assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of actin filament bundle assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	0.977
Apc	adenomatosis polyposis coli	0.960
Rac1	RAS-related C3 botulinum substrate 1	0.954	Human
Efnb2	ephrin B2	0.952
Ephb2	Eph receptor B2	0.906	Mouse
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.703
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.673
Ephb3	Eph receptor B3	0.453	Mouse
Gli3	GLI-Kruppel family member GLI3	0.446
Bcl2	B-cell leukemia/lymphoma 2	0.384
Efnb1	ephrin B1	0.379
Rarg	retinoic acid receptor, gamma	0.361
Ptch1	patched homolog 1	0.355
Fgf18	fibroblast growth factor 18	0.348
Wnt3a	wingless-related MMTV integration site 3A	0.328	Mouse
Wnt4	wingless-related MMTV integration site 4	0.309
Gli2	GLI-Kruppel family member GLI2	0.280
Enah	enabled homolog (Drosophila)	0.248
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.245
Epha4	Eph receptor A4	0.221	Mouse
Lhx1	LIM homeobox protein 1	0.221
Fgfr2	fibroblast growth factor receptor 2	0.215
Actb	actin, beta	0.201
Wdr1	WD repeat domain 1	0.169
Tbx2	T-box 2	0.168
Trp53	transformation related protein 53	0.159
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.150
Tead3	TEA domain family member 3	0.147
Hoxa13	homeobox A13	0.142
Nf1	neurofibromatosis 1	0.142
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.142
Trp73	transformation related protein 73	0.136
Vasp	vasodilator-stimulated phosphoprotein	0.128
Mapkap1	mitogen-activated protein kinase associated protein 1	0.122
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.117	Human
Rictor	RPTOR independent companion of MTOR, complex 2	0.114
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.114
Gata5	GATA binding protein 5	0.111
Wnt6	wingless-related MMTV integration site 6	0.110	Mouse
Fgf10	fibroblast growth factor 10	0.106
Kl	klotho	0.105
Pten	phosphatase and tensin homolog	0.103
Zfp651	zinc finger protein 651	0.102
Amhr2	anti-Mullerian hormone type 2 receptor	0.101
Smad6	MAD homolog 6 (Drosophila)	0.095
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.093
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.093
Efna4	ephrin A4	0.091
Bmp7	bone morphogenetic protein 7	0.091
Dnm1	dynamin 1	0.088
Rnd3	Rho family GTPase 3	0.088
Arhgap1	Rho GTPase activating protein 1	0.087
Vav2	vav 2 oncogene	0.082
Dmtf1	cyclin D binding myb-like transcription factor 1	0.080
Sox9	SRY-box containing gene 9	0.077
Lmx1a	LIM homeobox transcription factor 1 alpha	0.076
Pnoc	prepronociceptin	0.073
Hoxd13	homeobox D13	0.073
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.072
Unc5c	unc-5 homolog C (C. elegans)	0.071
Lrp5	low density lipoprotein receptor-related protein 5	0.069
Kit	kit oncogene	0.069
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.069
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.069
Kif5b	kinesin family member 5B	0.069
Itga3	integrin alpha 3	0.068
Sult5a1	sulfotransferase family 5A, member 1	0.064
Rb1	retinoblastoma 1	0.063
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.062
Rhoa	ras homolog gene family, member A	0.061	Human
Wipf1	WAS/WASL interacting protein family, member 1	0.058
Gli1	GLI-Kruppel family member GLI1	0.057
Npas1	neuronal PAS domain protein 1	0.055
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.054
Anxa2	annexin A2	0.054
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.053
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.053
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.052
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.052
Irs1	insulin receptor substrate 1	0.051
Nckap1	NCK-associated protein 1	0.051
Hspb8	heat shock protein 8	0.051
Lhx9	LIM homeobox protein 9	0.051
Plxna1	plexin A1	0.051
Lepr	leptin receptor	0.051
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.050
Pou3f3	POU domain, class 3, transcription factor 3	0.050
Ret	ret proto-oncogene	0.048
Braf	Braf transforming gene	0.047
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.047
Plxna3	plexin A3	0.046
Fzd8	frizzled homolog 8 (Drosophila)	0.046
Onecut1	one cut domain, family member 1	0.046
Ar	androgen receptor	0.046
Slk	STE20-like kinase (yeast)	0.046
Arpc4	actin related protein 2/3 complex, subunit 4	0.045
Jup	junction plakoglobin	0.045
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.045
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.045
Cyr61	cysteine rich protein 61	0.044
Dlx1	distal-less homeobox 1	0.044
Sh3rf1	SH3 domain containing ring finger 1	0.044
Esr2	estrogen receptor 2 (beta)	0.044
Fgfr1	fibroblast growth factor receptor 1	0.043
Porcn	porcupine homolog (Drosophila)	0.043
Tnks1bp1	tankyrase 1 binding protein 1	0.041
Sim2	single-minded homolog 2 (Drosophila)	0.041
Smad3	MAD homolog 3 (Drosophila)	0.041	Rat
Smad4	MAD homolog 4 (Drosophila)	0.041
Pou3f1	POU domain, class 3, transcription factor 1	0.040
Mdm2	transformed mouse 3T3 cell double minute 2	0.039
Srcin1	SRC kinase signaling inhibitor 1	0.039
Drd2	dopamine receptor D2	0.038
Vdr	vitamin D receptor	0.038
Smad2	MAD homolog 2 (Drosophila)	0.038
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.038
Acan	aggrecan	0.038
Src	Rous sarcoma oncogene	0.037
Emx1	empty spiracles homolog 1 (Drosophila)	0.037
Lrp6	low density lipoprotein receptor-related protein 6	0.036
Arf1	ADP-ribosylation factor 1	0.036
Rtkn	rhotekin	0.035
Fjx1	four jointed box 1 (Drosophila)	0.035
Cttn	cortactin	0.035
Sfrp1	secreted frizzled-related protein 1	0.034
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.034
Tgfb1	transforming growth factor, beta 1	0.034
Wnt10b	wingless related MMTV integration site 10b	0.034	Mouse
Mark4	MAP/microtubule affinity-regulating kinase 4	0.033
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.033
Pxn	paxillin	0.033
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.032
Dmgdh	dimethylglycine dehydrogenase precursor	0.031
Pou3f2	POU domain, class 3, transcription factor 2	0.031
Tead2	TEA domain family member 2	0.031
Dab1	disabled homolog 1 (Drosophila)	0.031
Wnt2b	wingless related MMTV integration site 2b	0.031	Mouse
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.031
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.031
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.031
Efna3	ephrin A3	0.031
Rptor	regulatory associated protein of MTOR, complex 1	0.030
Fzd1	frizzled homolog 1 (Drosophila)	0.030
Cd28	CD28 antigen	0.029
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.029
Wnt1	wingless-related MMTV integration site 1	0.029	Mouse
Wnt7b	wingless-related MMTV integration site 7B	0.029	Mouse
Apc2	adenomatosis polyposis coli 2	0.029
Scube1	signal peptide, CUB domain, EGF-like 1	0.028
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.028
Capzb	capping protein (actin filament) muscle Z-line, beta	0.027
Zap70	zeta-chain (TCR) associated protein kinase	0.027
Cdh6	cadherin 6	0.027
Lhb	luteinizing hormone beta	0.026
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.026	Fly
Otx1	orthodenticle homolog 1 (Drosophila)	0.026
Gdpd5	glycerophosphodiester phosphodiesterase domain containing 5	0.026
Plcg1	phospholipase C, gamma 1	0.025
Thbs1	thrombospondin 1	0.025
En1	engrailed 1	0.025
Sfrp2	secreted frizzled-related protein 2	0.025
Efna5	ephrin A5	0.025
Caskin2	CASK-interacting protein 2	0.025
Rara	retinoic acid receptor, alpha	0.024
Lef1	lymphoid enhancer binding factor 1	0.024
Hdac7	histone deacetylase 7	0.024
Fam83g	family with sequence similarity 83, member G	0.024
Col13a1	collagen, type XIII, alpha 1	0.024
Gdnf	glial cell line derived neurotrophic factor	0.024
Fam84a	family with sequence similarity 84, member A	0.023
Pvrl1	poliovirus receptor-related 1	0.023
Fgfr3	fibroblast growth factor receptor 3	0.023
Adamtsl5	ADAMTS-like 5	0.023
Hspa1a	heat shock protein 1A	0.023
Emid2	EMI domain containing 2	0.023
Ctnnd2	catenin (cadherin associated protein), delta 2	0.023
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.022
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.022
Apaf1	apoptotic peptidase activating factor 1	0.022
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.022
Pthlh	parathyroid hormone-like peptide	0.021
Grid1	glutamate receptor, ionotropic, delta 1	0.021
Plxna4	plexin A4	0.021
Phlda3	pleckstrin homology-like domain, family A, member 3	0.021
Clic3	chloride intracellular channel 3	0.021
Hic1	hypermethylated in cancer 1	0.021
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.021
Epha2	Eph receptor A2	0.021	Mouse
Gpr3	G-protein coupled receptor 3	0.021
Gata6	GATA binding protein 6	0.021
Amotl2	angiomotin-like 2	0.021
Lama5	laminin, alpha 5	0.020
Jag2	jagged 2	0.020
Bin1	bridging integrator 1	0.020
Socs1	suppressor of cytokine signaling 1	0.020
Grip1	glutamate receptor interacting protein 1	0.020
Skil	SKI-like	0.020
Msn	moesin	0.020
Axin2	axin2	0.020
Telo2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.019
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.019
Meis3	Meis homeobox 3	0.019
Wnt2	wingless-related MMTV integration site 2	0.019	Mouse
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.019
Nynrin	NYN domain and retroviral integrase containing	0.018
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.018
Gpr153	G protein-coupled receptor 153	0.018
Ccdc24	coiled-coil domain containing 24	0.018
Stk11	serine/threonine kinase 11	0.018
Fzd2	frizzled homolog 2 (Drosophila)	0.018
Mpz	myelin protein zero	0.018
Trp63	transformation related protein 63	0.018
T	brachyury	0.018
Zfpm2	zinc finger protein, multitype 2	0.018
Ppl	periplakin	0.018
6330403K07Rik	RIKEN cDNA 6330403K07 gene	0.018
Gsx1	GS homeobox 1	0.018
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.018
Ptk7	PTK7 protein tyrosine kinase 7	0.018
Fzd10	frizzled homolog 10 (Drosophila)	0.018
Gnao1	guanine nucleotide binding protein, alpha O	0.018
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.017
Efs	embryonal Fyn-associated substrate	0.017
Vav3	vav 3 oncogene	0.017
Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)	0.017
Il6st	interleukin 6 signal transducer	0.017
Wnt11	wingless-related MMTV integration site 11	0.017	Mouse
Lhx5	LIM homeobox protein 5	0.017
Grb10	growth factor receptor bound protein 10	0.017
Plxna2	plexin A2	0.017
Cfl1	cofilin 1, non-muscle	0.017
Gp1bb	glycoprotein Ib, beta polypeptide	0.017
Foxf2	forkhead box F2	0.017
Dlg1	discs, large homolog 1 (Drosophila)	0.017
Zfhx4	zinc finger homeodomain 4	0.017
Amh	anti-Mullerian hormone	0.017
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.016
Pkn2	protein kinase N2	0.016
Efna1	ephrin A1	0.016
Wasf1	WASP family 1	0.016
Apoc3	apolipoprotein C-III	0.016
Nf2	neurofibromatosis 2	0.016	Human
Capn2	calpain 2	0.016
Efna2	ephrin A2	0.016
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.016
Ptk2	PTK2 protein tyrosine kinase 2	0.016
Hif1a	hypoxia inducible factor 1, alpha subunit	0.016
Nes	nestin	0.016
Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	0.016
Gcgr	glucagon receptor	0.015
Atoh8	atonal homolog 8 (Drosophila)	0.015
H1fx	H1 histone family, member X	0.015
Tbx3	T-box 3	0.015
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.015
Pcgf2	polycomb group ring finger 2	0.015
Chst2	carbohydrate sulfotransferase 2	0.015
Gsk3b	glycogen synthase kinase 3 beta	0.015
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.015
Limk1	LIM-domain containing, protein kinase	0.015
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.015
Alx4	aristaless-like homeobox 4	0.015
Ihh	Indian hedgehog	0.014
Cdh4	cadherin 4	0.014
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.014
Foxf1a	forkhead box F1a	0.014
Clip2	CAP-GLY domain containing linker protein 2	0.014
Zic1	zinc finger protein of the cerebellum 1	0.014
Hoxd11	homeobox D11	0.014
Fosl2	fos-like antigen 2	0.014
Hhip	Hedgehog-interacting protein	0.014
Apoa2	apolipoprotein A-II	0.014
Mmp15	matrix metallopeptidase 15	0.014
Map2k2	mitogen-activated protein kinase kinase 2	0.014
Guca2b	guanylate cyclase activator 2b (retina)	0.014
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.014
Plec	plectin	0.014
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.014
Sorcs3	sortilin-related VPS10 domain containing receptor 3	0.014
Zeb1	zinc finger E-box binding homeobox 1	0.014
Stag2	stromal antigen 2	0.014
Foxn4	forkhead box N4	0.014
Emx2	empty spiracles homolog 2 (Drosophila)	0.014
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.014
Emp2	epithelial membrane protein 2	0.013
Ryk	receptor-like tyrosine kinase	0.013
Tgfa	transforming growth factor alpha	0.013
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.013
Cdx2	caudal type homeobox 2	0.013
Acr	acrosin prepropeptide	0.013
Sh3bp1	SH3-domain binding protein 1	0.013
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.013
Cux2	cut-like homeobox 2	0.013
Fzd6	frizzled homolog 6 (Drosophila)	0.013
Npas2	neuronal PAS domain protein 2	0.013
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.013
Kcnk2	potassium channel, subfamily K, member 2	0.013
Cd44	CD44 antigen	0.013
Hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.013
Kitl	kit ligand	0.013
Arhgef40	Rho guanine nucleotide exchange factor (GEF) 40	0.013
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.013
Vstm2b	V-set and transmembrane domain containing 2B	0.013
Pax8	paired box gene 8	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Rasa1	RAS p21 protein activator 1	0.013
Smo	smoothened homolog (Drosophila)	0.013
BC018242	cDNA sequence BC018242	0.013
Slc26a4	solute carrier family 26, member 4	0.013
Ctnnbip1	catenin beta interacting protein 1	0.013
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.012
Ctnna1	catenin (cadherin associated protein), alpha 1	0.012
Fgf5	fibroblast growth factor 5	0.012
Zfp703	zinc finger protein 703	0.012
Tbxa2r	thromboxane A2 receptor	0.012
Ano1	anoctamin 1, calcium activated chloride channel	0.012
Speg	SPEG complex locus	0.012
Ccnd1	cyclin D1	0.012
Sla	src-like adaptor	0.012
Npnt	nephronectin	0.012
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.012
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.012
Adra2b	adrenergic receptor, alpha 2b	0.012
Ctnna2	catenin (cadherin associated protein), alpha 2	0.012
Mark1	MAP/microtubule affinity-regulating kinase 1	0.012
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.012
Ntn3	netrin 3	0.012
Irx4	Iroquois related homeobox 4 (Drosophila)	0.012
Barx1	BarH-like homeobox 1	0.012
Arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.012
Hsbp1	heat shock factor binding protein 1	0.012
Mgat3	mannoside acetylglucosaminyltransferase 3	0.012
Rab10	RAB10, member RAS oncogene family	0.012
Irx1	Iroquois related homeobox 1 (Drosophila)	0.012
Kalrn	kalirin, RhoGEF kinase	0.012
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.012
Apoa5	apolipoprotein A-V	0.012
Wnt10a	wingless related MMTV integration site 10a	0.011
Cish	cytokine inducible SH2-containing protein	0.011
Col2a1	collagen, type II, alpha 1	0.011
Gab2	growth factor receptor bound protein 2-associated protein 2	0.011
Cnih2	cornichon homolog 2 (Drosophila)	0.011
Wnt5a	wingless-related MMTV integration site 5A	0.011	Mouse
Dlx4	distal-less homeobox 4	0.011
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.011
Mmp17	matrix metallopeptidase 17	0.011
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.011
Twist1	twist homolog 1 (Drosophila)	0.011
Cd48	CD48 antigen	0.011
Plcb3	phospholipase C, beta 3	0.011
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.011
Nog	noggin	0.011
Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)	0.011
Epha1	Eph receptor A1	0.011
Tcf7	transcription factor 7, T-cell specific	0.011
BC024139	cDNA sequence BC024139	0.011
Neurog1	neurogenin 1	0.011
Rspo1	R-spondin homolog (Xenopus laevis)	0.011
Adra2a	adrenergic receptor, alpha 2a	0.011
Amotl1	angiomotin-like 1	0.011
Sox7	SRY-box containing gene 7	0.011
En2	engrailed 2	0.011
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.011
Gal3st1	galactose-3-O-sulfotransferase 1	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
Fgfrl1	fibroblast growth factor receptor-like 1	0.011
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.010
Wnt3	wingless-related MMTV integration site 3	0.010	Mouse
Gata4	GATA binding protein 4	0.010
Cdx1	caudal type homeobox 1	0.010
Dock1	dedicator of cytokinesis 1	0.010
Snai1	snail homolog 1 (Drosophila)	0.010
Rp2h	retinitis pigmentosa 2 homolog (human)	0.010
E2f1	E2F transcription factor 1	0.010
Barx2	BarH-like homeobox 2	0.010
Homer2	homer homolog 2 (Drosophila)	0.010
Nckap5l	NCK-associated protein 5-like	0.010
Ahr	aryl-hydrocarbon receptor	0.010
Slmap	sarcolemma associated protein	0.010