IMP

Process View

Mus musculus

4 genes annotated in mouse

skeletal myofibril assembly

The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "skeletal myofibril assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "skeletal myofibril assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.998
Pfn1	profilin 1	0.996
Actc1	actin, alpha, cardiac muscle 1	0.985
Tnnt3	troponin T3, skeletal, fast	0.958	Fly
Ldb3	LIM domain binding 3	0.944
Actn2	actinin alpha 2	0.892
Myl3	myosin, light polypeptide 3	0.833
Tnni2	troponin I, skeletal, fast 2	0.823
Acta1	actin, alpha 1, skeletal muscle	0.813	Human Mouse
Rac1	RAS-related C3 botulinum substrate 1	0.777
Tagln	transgelin	0.768
Tnnc1	troponin C, cardiac/slow skeletal	0.740
Csrp3	cysteine and glycine-rich protein 3	0.710
Tnnc2	troponin C2, fast	0.697
Myom1	myomesin 1	0.649
Myl9	myosin, light polypeptide 9, regulatory	0.643
Actg1	actin, gamma, cytoplasmic 1	0.620	Mouse
Ckmt2	creatine kinase, mitochondrial 2	0.613
Casq2	calsequestrin 2	0.607
Pgam2	phosphoglycerate mutase 2	0.606
Hrc	histidine rich calcium binding protein	0.589
Cnn1	calponin 1	0.502
Hdac4	histone deacetylase 4	0.500
Tpm4	tropomyosin 4	0.497
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.466
Myl1	myosin, light polypeptide 1	0.465
Capzb	capping protein (actin filament) muscle Z-line, beta	0.430
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.421
Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	0.420	Zebrafish Mouse Worm Fly
Tnnt2	troponin T2, cardiac	0.413	Fly
Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	0.404
Ttn	titin	0.371
Des	desmin	0.323
Cox8b	cytochrome c oxidase, subunit VIIIb	0.318
Actb	actin, beta	0.282	Mouse
Cfl1	cofilin 1, non-muscle	0.281
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.275	Fly
Actg2	actin, gamma 2, smooth muscle, enteric	0.273	Mouse
Tnnt1	troponin T1, skeletal, slow	0.266	Fly
Tpm2	tropomyosin 2, beta	0.264
Wdr1	WD repeat domain 1	0.253	Worm
Myom2	myomesin 2	0.251
Ryr1	ryanodine receptor 1, skeletal muscle	0.241
Pdlim3	PDZ and LIM domain 3	0.237
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.218
Hspb2	heat shock protein 2	0.217
Nrap	nebulin-related anchoring protein	0.212
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.191
Cav3	caveolin 3	0.185
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.184
Rpgrip1l	Rpgrip1-like	0.179
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.171
Tuba1a	tubulin, alpha 1A	0.171
Arf1	ADP-ribosylation factor 1	0.170
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.168
Actn3	actinin alpha 3	0.160
Ckm	creatine kinase, muscle	0.157
Acta2	actin, alpha 2, smooth muscle, aorta	0.156	Mouse
Cryab	crystallin, alpha B	0.155
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.153
Prkce	protein kinase C, epsilon	0.147
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.146
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.144
Kbtbd5	kelch repeat and BTB (POZ) domain containing 5	0.135
Csrp1	cysteine and glycine-rich protein 1	0.135
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.130
Myh9	myosin, heavy polypeptide 9, non-muscle	0.129
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.123
Vasp	vasodilator-stimulated phosphoprotein	0.121
Itgb1bp2	integrin beta 1 binding protein 2	0.120
Flnc	filamin C, gamma	0.119
Msn	moesin	0.118
Myoz2	myozenin 2	0.118
Mef2c	myocyte enhancer factor 2C	0.117	Zebrafish
Casq1	calsequestrin 1	0.110
Mrvi1	MRV integration site 1	0.110
Xirp1	xin actin-binding repeat containing 1	0.108
Tmsb4x	thymosin, beta 4, X chromosome	0.107
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.095
Trim54	tripartite motif-containing 54	0.093
Cnn2	calponin 2	0.093
Tnni3	troponin I, cardiac 3	0.092
Arhgap1	Rho GTPase activating protein 1	0.089
Srpk3	serine/arginine-rich protein specific kinase 3	0.087
Hdac5	histone deacetylase 5	0.087
Rhoa	ras homolog gene family, member A	0.077	Worm
Lmod2	leiomodin 2 (cardiac)	0.074
Pygm	muscle glycogen phosphorylase	0.073
Fbxo32	F-box protein 32	0.071
Popdc3	popeye domain containing 3	0.069
Calm1	calmodulin 1	0.068
Hopx	HOP homeobox	0.067
Gnb1	guanine nucleotide binding protein (G protein), beta 1	0.067
Mef2d	myocyte enhancer factor 2D	0.064	Zebrafish
Arpc4	actin related protein 2/3 complex, subunit 4	0.064
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.062
Myl7	myosin, light polypeptide 7, regulatory	0.061
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.060	Zebrafish Mouse Worm Fly
Lmod3	leiomodin 3 (fetal)	0.059
Tpm1	tropomyosin 1, alpha	0.058
Myh2	myosin, heavy polypeptide 2, skeletal muscle, adult	0.058
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.053
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.053
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.052
Fhl2	four and a half LIM domains 2	0.052
Rrad	Ras-related associated with diabetes	0.051
Rtn2	reticulon 2 (Z-band associated protein)	0.050
Trdn	triadin	0.049
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.048
Tpm3	tropomyosin 3, gamma	0.047
Ryr2	ryanodine receptor 2, cardiac	0.046
Pdlim7	PDZ and LIM domain 7	0.046
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.045
Cltc	clathrin, heavy polypeptide (Hc)	0.045
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.044	Mouse Worm Fly
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.043
Trim63	tripartite motif-containing 63	0.042
Clec3b	C-type lectin domain family 3, member b	0.042
Txlnb	taxilin beta	0.042
Fabp3	fatty acid binding protein 3, muscle and heart	0.040
Smpx	small muscle protein, X-linked	0.040
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.039
Arpc2	actin related protein 2/3 complex, subunit 2	0.038
Hspb1	heat shock protein 1	0.037
Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.036
Itch	itchy, E3 ubiquitin protein ligase	0.036
Hspb3	heat shock protein 3	0.036
Cotl1	coactosin-like 1 (Dictyostelium)	0.035
Kbtbd10	kelch repeat and BTB (POZ) domain containing 10	0.035
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.035
Krt15	keratin 15	0.035
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.035
Cttn	cortactin	0.034
Tagln2	transgelin 2	0.034
Tcap	titin-cap	0.034	Human
Tubb2a	tubulin, beta 2A	0.034
Synpo2l	synaptopodin 2-like	0.034
Bves	blood vessel epicardial substance	0.033
Mlf1	myeloid leukemia factor 1	0.033
Hdac9	histone deacetylase 9	0.032
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.032
Myl4	myosin, light polypeptide 4	0.032
Asb2	ankyrin repeat and SOCS box-containing 2	0.031
Myom3	myomesin family, member 3	0.031
Mustn1	musculoskeletal, embryonic nuclear protein 1	0.031
Pdlim5	PDZ and LIM domain 5	0.030
Mef2a	myocyte enhancer factor 2A	0.030
Myot	myotilin	0.029
Art1	ADP-ribosyltransferase 1	0.029
Hspa8	heat shock protein 8	0.029
Rps28	ribosomal protein S28	0.028
Actn1	actinin, alpha 1	0.028
Fbn2	fibrillin 2	0.027
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.026
Glipr2	GLI pathogenesis-related 2	0.026
Pvalb	parvalbumin	0.026
Capn3	calpain 3	0.026
Sh3bgr	SH3-binding domain glutamic acid-rich protein	0.026
Ppia	peptidylprolyl isomerase A	0.025
Ptma	prothymosin alpha	0.025
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.024
Anxa2	annexin A2	0.024
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.024
Rpl3l	ribosomal protein L3-like	0.023
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.023
Murc	muscle-related coiled-coil protein	0.023
Crabp2	cellular retinoic acid binding protein II	0.023
Clec1b	C-type lectin domain family 1, member b	0.023
Mylk4	myosin light chain kinase family, member 4	0.023
Flna	filamin, alpha	0.023
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.023
Obscn	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.023	Worm
Rbm24	RNA binding motif protein 24	0.022
Cxadr	coxsackie virus and adenovirus receptor	0.021
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.021
Tmod4	tropomodulin 4	0.021
Mybph	myosin binding protein H	0.021
Vim	vimentin	0.021
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.021
Myf6	myogenic factor 6	0.021
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.021
Canx	calnexin	0.021
Ehd1	EH-domain containing 1	0.020
Hspa5	heat shock protein 5	0.020
Rbm20	RNA binding motif protein 20	0.020
Prr13	proline rich 13	0.020
Tuba1b	tubulin, alpha 1B	0.020
Tuba4a	tubulin, alpha 4A	0.020
Tmod1	tropomodulin 1	0.019
Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.019
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.019
Fsd2	fibronectin type III and SPRY domain containing 2	0.019
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.019
Mb	myoglobin	0.019
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.019
Eno3	enolase 3, beta muscle	0.019
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.019
Klhl30	kelch-like 30 (Drosophila)	0.019
Wsb2	WD repeat and SOCS box-containing 2	0.018
Coro1c	coronin, actin binding protein 1C	0.018
2900073G15Rik	RIKEN cDNA 2900073G15 gene	0.018
Wfdc1	WAP four-disulfide core domain 1	0.018
2310046A06Rik	RIKEN cDNA 2310046A06 gene	0.018
Ptrf	polymerase I and transcript release factor	0.018
Dysfip1	dysferlin interacting protein 1	0.017
Popdc2	popeye domain containing 2	0.017
Eif4a1	eukaryotic translation initiation factor 4A1	0.017
Tubb6	tubulin, beta 6	0.017
Neb	nebulin	0.017
Tnni1	troponin I, skeletal, slow 1	0.017
Fgb	fibrinogen beta chain	0.017
Ckb	creatine kinase, brain	0.017
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.017
Psap	prosaposin	0.017
Zeb2	zinc finger E-box binding homeobox 2	0.017
Loxl2	lysyl oxidase-like 2	0.017
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.016
Mybpc1	myosin binding protein C, slow-type	0.016
Cmya5	cardiomyopathy associated 5	0.016
Nppa	natriuretic peptide type A	0.016
Hamp	hepcidin antimicrobial peptide	0.016
Dhrs7c	dehydrogenase/reductase (SDR family) member 7C	0.016
Lmod1	leiomodin 1 (smooth muscle)	0.016
Hbegf	heparin-binding EGF-like growth factor	0.016
Agr2	anterior gradient 2 (Xenopus laevis)	0.016
Pde1c	phosphodiesterase 1C	0.015
Dusp27	dual specificity phosphatase 27 (putative)	0.015
Map2k4	mitogen-activated protein kinase kinase 4	0.015
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.015
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.015
Ptgis	prostaglandin I2 (prostacyclin) synthase	0.015
Myoz1	myozenin 1	0.015
Rxrg	retinoid X receptor gamma	0.015
Hspb8	heat shock protein 8	0.015
1110002E22Rik	RIKEN cDNA 1110002E22 gene	0.015
Pja2	praja 2, RING-H2 motif containing	0.015
Tln1	talin 1	0.015
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.015
Ralb	v-ral simian leukemia viral oncogene homolog B (ras related)	0.015
Gm8894	predicted gene 8894	0.015
Gna13	guanine nucleotide binding protein, alpha 13	0.015
Tmem182	transmembrane protein 182	0.015
Nsf	N-ethylmaleimide sensitive fusion protein	0.014
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.014
Ctnnd1	catenin (cadherin associated protein), delta 1	0.014
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.014
Ubc	ubiquitin C	0.014
Myadm	myeloid-associated differentiation marker	0.014
Tmsb10	thymosin, beta 10	0.014
Fli1	Friend leukemia integration 1	0.014
Dync1li1	dynein cytoplasmic 1 light intermediate chain 1	0.014
Plxna2	plexin A2	0.013
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.013
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.013
1700113I22Rik	RIKEN cDNA 1700113I22 gene	0.013
Clic1	chloride intracellular channel 1	0.013
Lmna	lamin A	0.013
Rtkn	rhotekin	0.013
Ugcg	UDP-glucose ceramide glucosyltransferase	0.013
Ppapdc3	phosphatidic acid phosphatase type 2 domain containing 3	0.013
Pgf	placental growth factor	0.013
Mypn	myopalladin	0.013
Fxyd1	FXYD domain-containing ion transport regulator 1	0.013
Map2k1	mitogen-activated protein kinase kinase 1	0.013
Art3	ADP-ribosyltransferase 3	0.013
Stac3	SH3 and cysteine rich domain 3	0.013
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.013
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.013
Iqgap1	IQ motif containing GTPase activating protein 1	0.013
Synpo2	synaptopodin 2	0.013
Asb10	ankyrin repeat and SOCS box-containing 10	0.013
Tceal7	transcription elongation factor A (SII)-like 7	0.013
Nexn	nexilin	0.013
Abra	actin-binding Rho activating protein	0.012
Cox7a1	cytochrome c oxidase, subunit VIIa 1	0.012
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.012
Asb14	ankyrin repeat and SOCS box-containing 14	0.012
Scn4b	sodium channel, type IV, beta	0.012
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.012
Clic4	chloride intracellular channel 4 (mitochondrial)	0.012
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.012
Rab4b	RAB4B, member RAS oncogene family	0.012
Ankrd23	ankyrin repeat domain 23	0.012
Unc45b	unc-45 homolog B (C. elegans)	0.012
Tcea3	transcription elongation factor A (SII), 3	0.012
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.012
Thbs4	thrombospondin 4	0.012
Mylk3	myosin light chain kinase 3	0.012
Spnb2	spectrin beta 2	0.012
Alpk2	alpha-kinase 2	0.012
Pvr	poliovirus receptor	0.012
Car3	carbonic anhydrase 3	0.012
Clic5	chloride intracellular channel 5	0.012
Mylk	myosin, light polypeptide kinase	0.012
Srl	sarcalumenin	0.012
Xiap	X-linked inhibitor of apoptosis	0.011
Tekt1	tektin 1	0.011
S100a6	S100 calcium binding protein A6 (calcyclin)	0.011
Spop	speckle-type POZ protein	0.011
4930548H24Rik	RIKEN cDNA 4930548H24 gene	0.011
Prkcq	protein kinase C, theta	0.011
Camta2	calmodulin binding transcription activator 2	0.011
Igfbp6	insulin-like growth factor binding protein 6	0.011
Adm	adrenomedullin	0.011
Ahi1	Abelson helper integration site 1	0.011
Bag2	BCL2-associated athanogene 2	0.011
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.011
Tecrl	trans-2,3-enoyl-CoA reductase-like	0.011
2310002L09Rik	RIKEN cDNA 2310002L09 gene	0.011
Neurl2	neuralized-like 2 (Drosophila)	0.011
Kif1b	kinesin family member 1B	0.011
Serpinb3a	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A	0.011
Tes	testis derived transcript	0.011
Mug1	murinoglobulin 1	0.011
Ivl	involucrin	0.011
Palm2	paralemmin 2	0.011
Higd1b	HIG1 domain family, member 1B	0.011
Myh7b	myosin, heavy chain 7B, cardiac muscle, beta	0.011
Mapk10	mitogen-activated protein kinase 10	0.011
Lrrc2	leucine rich repeat containing 2	0.011
1700061J05Rik	RIKEN cDNA 1700061J05 gene	0.011
Pecam1	platelet/endothelial cell adhesion molecule 1	0.011
Rragd	Ras-related GTP binding D	0.011
Timp1	tissue inhibitor of metalloproteinase 1	0.011
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.011
Actn4	actinin alpha 4	0.011
Tceal3	transcription elongation factor A (SII)-like 3	0.011
4930578I06Rik	RIKEN cDNA 4930578I06 gene	0.010
Mtap4	microtubule-associated protein 4	0.010
Pde4d	phosphodiesterase 4D, cAMP specific	0.010
Gmfb	glia maturation factor, beta	0.010
Rasl10a	RAS-like, family 10, member A	0.010
Myadml2	myeloid-associated differentiation marker-like 2	0.010
Tmem38a	transmembrane protein 38A	0.010
Col1a2	collagen, type I, alpha 2	0.010
Junb	Jun-B oncogene	0.010
Clip4	CAP-GLY domain containing linker protein family, member 4	0.010
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.010
Myocd	myocardin	0.010
Pde4dip	phosphodiesterase 4D interacting protein (myomegalin)	0.010
Fbn1	fibrillin 1	0.010
Mks1	Meckel syndrome, type 1	0.010
C030019I05Rik	RIKEN cDNA C030019I05 gene	0.010
Wnt11	wingless-related MMTV integration site 11	0.010
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.010
Trpc6	transient receptor potential cation channel, subfamily C, member 6	0.010