IMP

Process View

Mus musculus

8 genes annotated in mouse

Multi-species View

regulation of defense response to virus by host

GO:0050691

Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of defense response to virus by host"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of defense response to virus by host" (in gray)

Name	Description	Probability	Func Analog Organism
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.998	Fly
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.994
Gbp7	guanylate binding protein 7	0.986
Stat1	signal transducer and activator of transcription 1	0.979
Irgm1	immunity-related GTPase family M member 1	0.976
Irgm2	immunity-related GTPase family M member 2	0.945
Gbp3	guanylate binding protein 3	0.945
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.937
Usp18	ubiquitin specific peptidase 18	0.930
Gbp2	guanylate binding protein 2	0.928
Trim21	tripartite motif-containing 21	0.925
Tnf	tumor necrosis factor	0.919
Ikbkg	inhibitor of kappaB kinase gamma	0.900
Casp1	caspase 1	0.896	Fly
Igtp	interferon gamma induced GTPase	0.893
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.874
Irf1	interferon regulatory factor 1	0.857	Mouse
Ifih1	interferon induced with helicase C domain 1	0.856
Trim30a	tripartite motif-containing 30A	0.825
Stat5a	signal transducer and activator of transcription 5A	0.821	Fly
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.796
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.751
Gbp5	guanylate binding protein 5	0.743
Irf9	interferon regulatory factor 9	0.717	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.716
Uba7	ubiquitin-like modifier activating enzyme 7	0.687
Stat3	signal transducer and activator of transcription 3	0.672
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.655	Human
Iigp1	interferon inducible GTPase 1	0.646
Ifi47	interferon gamma inducible protein 47	0.627
Lyz2	lysozyme 2	0.555
Isg15	ISG15 ubiquitin-like modifier	0.554
Ikzf1	IKAROS family zinc finger 1	0.469
Tgtp2	T-cell specific GTPase 2	0.447
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.419
Rtp4	receptor transporter protein 4	0.416
Mndal	myeloid nuclear differentiation antigen like	0.396
Trim25	tripartite motif-containing 25	0.392
Parp14	poly (ADP-ribose) polymerase family, member 14	0.363
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.342
Pycard	PYD and CARD domain containing	0.323
Rsad2	radical S-adenosyl methionine domain containing 2	0.317
AW112010	expressed sequence AW112010	0.315
Tor3a	torsin family 3, member A	0.309
Stat5b	signal transducer and activator of transcription 5B	0.309	Fly
Igh	immunoglobulin heavy chain complex	0.307
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.304
Sp100	nuclear antigen Sp100	0.301
Ikbkb	inhibitor of kappaB kinase beta	0.296	Fly
Irf7	interferon regulatory factor 7	0.281	Mouse
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.271
Zbp1	Z-DNA binding protein 1	0.262
Aim2	absent in melanoma 2	0.260
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.242
Myd88	myeloid differentiation primary response gene 88	0.221
Parp9	poly (ADP-ribose) polymerase family, member 9	0.207
Ifi35	interferon-induced protein 35	0.194
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.158
Stat2	signal transducer and activator of transcription 2	0.154
Cd40	CD40 antigen	0.139
Samd9l	sterile alpha motif domain containing 9-like	0.125
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.124
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.120	Fly
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.111
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.107
Il10	interleukin 10	0.105
Trp53	transformation related protein 53	0.104
Nmi	N-myc (and STAT) interactor	0.093
Il15ra	interleukin 15 receptor, alpha chain	0.089
Unc93b1	unc-93 homolog B1 (C. elegans)	0.089
Mx1	myxovirus (influenza virus) resistance 1	0.088
Mx2	myxovirus (influenza virus) resistance 2	0.085
Ifi44	interferon-induced protein 44	0.081
Cd19	CD19 antigen	0.080
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.077
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.076
Tapbp	TAP binding protein	0.071
Ifng	interferon gamma	0.070
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.068
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.065
Foxn1	forkhead box N1	0.060
BC006779	cDNA sequence BC006779	0.059
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.058
Znfx1	zinc finger, NFX1-type containing 1	0.056
Ifi203	interferon activated gene 203	0.055	Mouse
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.051
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.051
Fas	Fas (TNF receptor superfamily member 6)	0.051
Parp10	poly (ADP-ribose) polymerase family, member 10	0.046
Rnf31	ring finger protein 31	0.045
Cxcl10	chemokine (C-X-C motif) ligand 10	0.043
Plcg2	phospholipase C, gamma 2	0.041
Ifnar2	interferon (alpha and beta) receptor 2	0.041
Parp12	poly (ADP-ribose) polymerase family, member 12	0.041
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.041
Daxx	Fas death domain-associated protein	0.040
Il4ra	interleukin 4 receptor, alpha	0.040
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.038
Dtx3l	deltex 3-like (Drosophila)	0.038
Ticam1	toll-like receptor adaptor molecule 1	0.036
Traf3	TNF receptor-associated factor 3	0.036
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.035
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.034
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.034
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.033
Lta	lymphotoxin A	0.033
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.032
Nlrp3	NLR family, pyrin domain containing 3	0.031
Tlr4	toll-like receptor 4	0.031
H2-M3	histocompatibility 2, M region locus 3	0.030
Pyhin1	pyrin and HIN domain family, member 1	0.030
Prkcd	protein kinase C, delta	0.030
Trim30d	tripartite motif-containing 30D	0.030
Vdr	vitamin D receptor	0.029
Gvin1	GTPase, very large interferon inducible 1	0.029
Bcl3	B-cell leukemia/lymphoma 3	0.029
Traf6	TNF receptor-associated factor 6	0.029
Sfpi1	SFFV proviral integration 1	0.028
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.028
Il18	interleukin 18	0.026
Skil	SKI-like	0.025
Lgals9	lectin, galactose binding, soluble 9	0.025
Adar	adenosine deaminase, RNA-specific	0.024
Rnf135	ring finger protein 135	0.024
Herc6	hect domain and RLD 6	0.023
Sfn	stratifin	0.023
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.022
Traf2	TNF receptor-associated factor 2	0.022
Prf1	perforin 1 (pore forming protein)	0.021
Casp8	caspase 8	0.021
Pml	promyelocytic leukemia	0.020	Human
Samhd1	SAM domain and HD domain, 1	0.020
Irf8	interferon regulatory factor 8	0.019	Mouse
Slfn2	schlafen 2	0.019
Tnip1	TNFAIP3 interacting protein 1	0.019
Foxp3	forkhead box P3	0.019
Ncoa3	nuclear receptor coactivator 3	0.019
Ciita	class II transactivator	0.018
Il23a	interleukin 23, alpha subunit p19	0.018
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.018
Prlr	prolactin receptor	0.018
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.018
Birc3	baculoviral IAP repeat-containing 3	0.017
Bcl6	B-cell leukemia/lymphoma 6	0.017
Csf1	colony stimulating factor 1 (macrophage)	0.016
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.016
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.016	Human
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.016
Oas1a	2'-5' oligoadenylate synthetase 1A	0.016
Dock2	dedicator of cyto-kinesis 2	0.015
Blnk	B-cell linker	0.015
Erap1	endoplasmic reticulum aminopeptidase 1	0.015
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.015
Il2rg	interleukin 2 receptor, gamma chain	0.015
Ankfy1	ankyrin repeat and FYVE domain containing 1	0.014
Tlr3	toll-like receptor 3	0.014
Ikbke	inhibitor of kappaB kinase epsilon	0.014
Il15	interleukin 15	0.014
Mnda	myeloid cell nuclear differentiation antigen	0.014
Il27ra	interleukin 27 receptor, alpha	0.014
Sp1	trans-acting transcription factor 1	0.014
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.014
Il2rb	interleukin 2 receptor, beta chain	0.013
H2-T24	histocompatibility 2, T region locus 24	0.013
Il12b	interleukin 12b	0.013
Nckap1l	NCK associated protein 1 like	0.013
Aim1	absent in melanoma 1	0.012
Gbp6	guanylate binding protein 6	0.012
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.012
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.012
Trp63	transformation related protein 63	0.011
Stk4	serine/threonine kinase 4	0.011
Jak3	Janus kinase 3	0.011
Trim34a	tripartite motif-containing 34A	0.011
Irf4	interferon regulatory factor 4	0.011	Mouse
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.011
Prdm1	PR domain containing 1, with ZNF domain	0.011
Esr1	estrogen receptor 1 (alpha)	0.011
Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	0.011
Sykb	spleen tyrosine kinase	0.010
Chuk	conserved helix-loop-helix ubiquitous kinase	0.010	Fly
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.010