IMP
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negative regulation of gene expression epigenetic
Any epigenetic process that stops, prevents or reduces the rate of gene expression.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of gene expression epigenetic"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Rnf2 | ring finger protein 2 | 0.999 | Worm Fly | |
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.996 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.996 | Human | |
| Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.993 | ||
| Rbbp4 | retinoblastoma binding protein 4 | 0.970 | Yeast Fly | |
| Hdac1 | histone deacetylase 1 | 0.960 | Fly | |
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.896 | Human | |
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.886 | Mouse | |
| Mcm2 | minichromosome maintenance deficient 2 mitotin (S. cerevisiae) | 0.813 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.801 | ||
| Ctcf | CCCTC-binding factor | 0.789 | ||
| Rybp | RING1 and YY1 binding protein | 0.670 | ||
| Trp53 | transformation related protein 53 | 0.655 | ||
| Mcm4 | minichromosome maintenance deficient 4 homolog (S. cerevisiae) | 0.565 | ||
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.559 | Yeast | |
| H3f3a | H3 histone, family 3A | 0.542 | ||
| Brca1 | breast cancer 1 | 0.508 | ||
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.502 | ||
| Smc1a | structural maintenance of chromosomes 1A | 0.489 | ||
| Smc3 | structural maintenace of chromosomes 3 | 0.467 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.434 | ||
| Hdac2 | histone deacetylase 2 | 0.410 | Human Fly | |
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.376 | ||
| Wdr5 | WD repeat domain 5 | 0.369 | ||
| Uhrf1 | ubiquitin-like, containing PHD and RING finger domains, 1 | 0.366 | ||
| Cbx5 | chromobox homolog 5 (Drosophila HP1a) | 0.355 | Fly | |
| Igh | immunoglobulin heavy chain complex | 0.348 | ||
| Ep400 | E1A binding protein p400 | 0.346 | ||
| Ep300 | E1A binding protein p300 | 0.316 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.310 | ||
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.304 | ||
| Stag1 | stromal antigen 1 | 0.292 | ||
| Tcf3 | transcription factor 3 | 0.286 | ||
| Ash2l | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.271 | ||
| Nanog | Nanog homeobox | 0.269 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.256 | Human Yeast | |
| Mcm5 | minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 0.240 | Yeast | |
| Kdm2b | lysine (K)-specific demethylase 2B | 0.240 | ||
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.234 | Yeast | |
| Mta2 | metastasis-associated gene family, member 2 | 0.229 | ||
| Cdt1 | chromatin licensing and DNA replication factor 1 | 0.170 | ||
| Dnmt3b | DNA methyltransferase 3B | 0.158 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.154 | ||
| Sp1 | trans-acting transcription factor 1 | 0.149 | ||
| Arid2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.136 | Fly | |
| Timeless | timeless homolog (Drosophila) | 0.129 | ||
| Trim28 | tripartite motif-containing 28 | 0.127 | ||
| Cdk1 | cyclin-dependent kinase 1 | 0.121 | ||
| Pold1 | polymerase (DNA directed), delta 1, catalytic subunit | 0.119 | ||
| Rcc2 | regulator of chromosome condensation 2 | 0.117 | ||
| Mta1 | metastasis associated 1 | 0.106 | ||
| Hells | helicase, lymphoid specific | 0.106 | ||
| Hist1h3g | histone cluster 1, H3g | 0.105 | ||
| Crebbp | CREB binding protein | 0.105 | ||
| Ccna2 | cyclin A2 | 0.101 | ||
| E2f1 | E2F transcription factor 1 | 0.101 | ||
| Bmi1 | Bmi1 polycomb ring finger oncogene | 0.101 | Fly | |
| Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.097 | Fly | |
| Lig1 | ligase I, DNA, ATP-dependent | 0.094 | ||
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.086 | ||
| Mga | MAX gene associated | 0.082 | ||
| Cbx8 | chromobox homolog 8 (Drosophila Pc class) | 0.073 | ||
| Dnmt3a | DNA methyltransferase 3A | 0.071 | ||
| Brd4 | bromodomain containing 4 | 0.070 | ||
| Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.069 | Yeast Mouse | |
| Brca2 | breast cancer 2 | 0.065 | ||
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.063 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.062 | ||
| Lrwd1 | leucine-rich repeats and WD repeat domain containing 1 | 0.062 | ||
| Phc2 | polyhomeotic-like 2 (Drosophila) | 0.061 | ||
| Matr3 | matrin 3 | 0.061 | ||
| Csnk1a1 | casein kinase 1, alpha 1 | 0.060 | ||
| Skp1a | S-phase kinase-associated protein 1A | 0.059 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.059 | ||
| Trim24 | tripartite motif-containing 24 | 0.057 | ||
| Safb | scaffold attachment factor B | 0.054 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.054 | ||
| Ccnb2 | cyclin B2 | 0.053 | ||
| Supt16h | suppressor of Ty 16 homolog (S. cerevisiae) | 0.052 | ||
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.052 | ||
| Erg | avian erythroblastosis virus E-26 (v-ets) oncogene related | 0.050 | ||
| Hmgb1 | high mobility group box 1 | 0.050 | ||
| Tfdp1 | transcription factor Dp 1 | 0.048 | ||
| Krit1 | KRIT1, ankyrin repeat containing | 0.047 | ||
| H2afz | H2A histone family, member Z | 0.045 | Yeast | |
| Suds3 | suppressor of defective silencing 3 homolog (S. cerevisiae) | 0.044 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.043 | Yeast | |
| Rrm1 | ribonucleotide reductase M1 | 0.043 | ||
| Rest | RE1-silencing transcription factor | 0.042 | ||
| Sae1 | SUMO1 activating enzyme subunit 1 | 0.042 | ||
| Pcgf2 | polycomb group ring finger 2 | 0.041 | Fly | |
| Sp4 | trans-acting transcription factor 4 | 0.041 | ||
| Ilf3 | interleukin enhancer binding factor 3 | 0.039 | ||
| Eed | embryonic ectoderm development | 0.039 | Fly | |
| Jarid2 | jumonji, AT rich interactive domain 2 | 0.037 | ||
| Scaf11 | SR-related CTD-associated factor 11 | 0.037 | ||
| Lmnb1 | lamin B1 | 0.037 | Fly | |
| Pcgf6 | polycomb group ring finger 6 | 0.037 | ||
| Nucks1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.037 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.036 | ||
| Orc6 | origin recognition complex, subunit 6 | 0.036 | ||
| Bptf | bromodomain PHD finger transcription factor | 0.035 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.035 | ||
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.035 | ||
| Mbtd1 | mbt domain containing 1 | 0.034 | Fly | |
| Ncapd2 | non-SMC condensin I complex, subunit D2 | 0.033 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.033 | Fly | |
| Atm | ataxia telangiectasia mutated homolog (human) | 0.032 | Fly | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.032 | ||
| Hcfc1 | host cell factor C1 | 0.032 | ||
| Tcf12 | transcription factor 12 | 0.032 | ||
| L3mbtl2 | l(3)mbt-like 2 (Drosophila) | 0.031 | Fly | |
| Cdca8 | cell division cycle associated 8 | 0.031 | ||
| Rcc1 | regulator of chromosome condensation 1 | 0.031 | ||
| Baz1b | bromodomain adjacent to zinc finger domain, 1B | 0.031 | ||
| Usp7 | ubiquitin specific peptidase 7 | 0.031 | Fly | |
| Runx1 | runt related transcription factor 1 | 0.030 | ||
| Cdca7 | cell division cycle associated 7 | 0.030 | ||
| Sos2 | son of sevenless homolog 2 (Drosophila) | 0.030 | ||
| Ddx3y | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked | 0.030 | ||
| Ptma | prothymosin alpha | 0.030 | ||
| Ncaph | non-SMC condensin I complex, subunit H | 0.030 | ||
| Rb1 | retinoblastoma 1 | 0.029 | ||
| Orc1 | origin recognition complex, subunit 1 | 0.029 | ||
| Ehmt1 | euchromatic histone methyltransferase 1 | 0.028 | ||
| Ncor1 | nuclear receptor co-repressor 1 | 0.028 | ||
| Anp32e | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.028 | ||
| Hdac3 | histone deacetylase 3 | 0.028 | ||
| Sfpq | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | 0.028 | ||
| Whsc1 | Wolf-Hirschhorn syndrome candidate 1 (human) | 0.027 | ||
| Fbxo5 | F-box protein 5 | 0.026 | ||
| Ring1 | ring finger protein 1 | 0.026 | Worm Fly | |
| Smc2 | structural maintenance of chromosomes 2 | 0.026 | ||
| Nipbl | Nipped-B homolog (Drosophila) | 0.026 | ||
| Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.026 | ||
| Rrm2 | ribonucleotide reductase M2 | 0.026 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.025 | ||
| Yy1 | YY1 transcription factor | 0.025 | Fly | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.025 | ||
| Hnrnpk | heterogeneous nuclear ribonucleoprotein K | 0.025 | ||
| Pou2f1 | POU domain, class 2, transcription factor 1 | 0.025 | ||
| Rfc5 | replication factor C (activator 1) 5 | 0.025 | ||
| Max | Max protein | 0.025 | ||
| Hnrnpu | heterogeneous nuclear ribonucleoprotein U | 0.024 | ||
| Kdm5b | lysine (K)-specific demethylase 5B | 0.024 | ||
| Cry1 | cryptochrome 1 (photolyase-like) | 0.024 | ||
| Pcna | proliferating cell nuclear antigen | 0.024 | ||
| Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.023 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.023 | ||
| Smarcc2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.023 | ||
| Csnk2a1 | casein kinase 2, alpha 1 polypeptide | 0.023 | ||
| Hist1h2bc | histone cluster 1, H2bc | 0.022 | ||
| Ccne1 | cyclin E1 | 0.022 | ||
| Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.022 | ||
| Fen1 | flap structure specific endonuclease 1 | 0.022 | ||
| Chaf1a | chromatin assembly factor 1, subunit A (p150) | 0.021 | ||
| Nono | non-POU-domain-containing, octamer binding protein | 0.021 | ||
| Cbx7 | chromobox homolog 7 | 0.021 | ||
| Dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.021 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.021 | ||
| Bcor | BCL6 interacting corepressor | 0.021 | ||
| BC005537 | cDNA sequence BC005537 | 0.021 | ||
| Plcg2 | phospholipase C, gamma 2 | 0.020 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.020 | ||
| Mybbp1a | MYB binding protein (P160) 1a | 0.020 | ||
| Pold3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.020 | ||
| Fmr1 | fragile X mental retardation syndrome 1 homolog | 0.020 | ||
| Pten | phosphatase and tensin homolog | 0.020 | ||
| Hnrnpr | heterogeneous nuclear ribonucleoprotein R | 0.020 | ||
| Mms22l | MMS22-like, DNA repair protein | 0.019 | ||
| Cdca5 | cell division cycle associated 5 | 0.019 | ||
| Ckap5 | cytoskeleton associated protein 5 | 0.019 | ||
| Xrn1 | 5'-3' exoribonuclease 1 | 0.019 | ||
| Rpa2 | replication protein A2 | 0.019 | ||
| Eftud2 | elongation factor Tu GTP binding domain containing 2 | 0.019 | ||
| Pabpn1 | poly(A) binding protein, nuclear 1 | 0.019 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.019 | ||
| H2afx | H2A histone family, member X | 0.018 | Yeast | |
| Zc3h18 | zinc finger CCCH-type containing 18 | 0.018 | ||
| Rbm14 | RNA binding motif protein 14 | 0.018 | ||
| Smarce1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 0.018 | ||
| Cbx2 | chromobox homolog 2 (Drosophila Pc class) | 0.018 | ||
| Pabpc1 | poly(A) binding protein, cytoplasmic 1 | 0.018 | ||
| Ptges3 | prostaglandin E synthase 3 (cytosolic) | 0.018 | ||
| Dek | DEK oncogene (DNA binding) | 0.017 | ||
| Nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.017 | ||
| Jmjd1c | jumonji domain containing 1C | 0.017 | Fly | |
| Ccnf | cyclin F | 0.017 | ||
| Arid4b | AT rich interactive domain 4B (RBP1-like) | 0.016 | ||
| Ppp2ca | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 0.016 | ||
| Smc6 | structural maintenance of chromosomes 6 | 0.016 | ||
| Rnf220 | ring finger protein 220 | 0.016 | ||
| Acin1 | apoptotic chromatin condensation inducer 1 | 0.016 | ||
| Brd8 | bromodomain containing 8 | 0.016 | ||
| Sox2 | SRY-box containing gene 2 | 0.016 | ||
| Pcgf1 | polycomb group ring finger 1 | 0.016 | ||
| Atad2b | ATPase family, AAA domain containing 2B | 0.016 | ||
| Nup85 | nucleoporin 85 | 0.016 | ||
| Gnb2 | guanine nucleotide binding protein (G protein), beta 2 | 0.015 | ||
| Kdm6a | 4lysine (K)-specific demethylase 6A | 0.015 | Mouse | |
| Top2b | topoisomerase (DNA) II beta | 0.015 | Fly | |
| Morf4l1 | mortality factor 4 like 1 | 0.015 | ||
| Suv39h1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.015 | Human | |
| Myf5 | myogenic factor 5 | 0.015 | ||
| Spast | spastin | 0.015 | ||
| Rev3l | REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) | 0.014 | ||
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.014 | Yeast | |
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.014 | ||
| Rbbp6 | retinoblastoma binding protein 6 | 0.014 | ||
| Trrap | transformation/transcription domain-associated protein | 0.014 | ||
| Akap9 | A kinase (PRKA) anchor protein (yotiao) 9 | 0.014 | ||
| Dnmt3l | DNA (cytosine-5-)-methyltransferase 3-like | 0.014 | Mouse | |
| U2af2 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 | 0.014 | ||
| Mael | maelstrom homolog (Drosophila) | 0.014 | ||
| Prim1 | DNA primase, p49 subunit | 0.014 | ||
| Lbr | lamin B receptor | 0.014 | ||
| Blzf1 | basic leucine zipper nuclear factor 1 | 0.014 | ||
| Dnajc9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.013 | ||
| Asf1a | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.013 | ||
| Sept7 | septin 7 | 0.013 | ||
| Phc1 | polyhomeotic-like 1 (Drosophila) | 0.013 | ||
| Ctbp2 | C-terminal binding protein 2 | 0.013 | ||
| Cdc73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.013 | ||
| Zfp292 | zinc finger protein 292 | 0.013 | ||
| Tcf19 | transcription factor 19 | 0.013 | ||
| Cse1l | chromosome segregation 1-like (S. cerevisiae) | 0.013 | ||
| Tnrc6b | trinucleotide repeat containing 6b | 0.013 | ||
| Zbtb33 | zinc finger and BTB domain containing 33 | 0.013 | ||
| Rqcd1 | rcd1 (required for cell differentiation) homolog 1 (S. pombe) | 0.013 | ||
| Mcm6 | minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 0.013 | ||
| Nup188 | nucleoporin 188 | 0.013 | ||
| Mphosph9 | M-phase phosphoprotein 9 | 0.013 | ||
| Cenpn | centromere protein N | 0.013 | ||
| Cabin1 | calcineurin binding protein 1 | 0.013 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.013 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.012 | ||
| Chordc1 | cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 | 0.012 | ||
| Trim32 | tripartite motif-containing 32 | 0.012 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.012 | ||
| March7 | membrane-associated ring finger (C3HC4) 7 | 0.012 | ||
| Rpa1 | replication protein A1 | 0.012 | ||
| Ywhae | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.012 | ||
| Cbfb | core binding factor beta | 0.012 | ||
| Nacc1 | nucleus accumbens associated 1, BEN and BTB (POZ) domain containing | 0.012 | ||
| Hist2h3c1 | histone cluster 2, H3c1 | 0.012 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.012 | ||
| Rbl2 | retinoblastoma-like 2 | 0.012 | ||
| Tpr | translocated promoter region | 0.012 | ||
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.012 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.012 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.012 | ||
| C80913 | expressed sequence C80913 | 0.012 | ||
| Piwil2 | piwi-like homolog 2 (Drosophila) | 0.012 | Fly | |
| Gtf3c2 | general transcription factor IIIC, polypeptide 2, beta | 0.011 | ||
| Hn1 | hematological and neurological expressed sequence 1 | 0.011 | ||
| Ewsr1 | Ewing sarcoma breakpoint region 1 | 0.011 | ||
| Cramp1l | Crm, cramped-like (Drosophila) | 0.011 | ||
| Yaf2 | YY1 associated factor 2 | 0.011 | ||
| Wnk1 | WNK lysine deficient protein kinase 1 | 0.011 | ||
| Ncapd3 | non-SMC condensin II complex, subunit D3 | 0.011 | ||
| Cad | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.011 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.011 | ||
| Phc3 | polyhomeotic-like 3 (Drosophila) | 0.011 | ||
| Ints7 | integrator complex subunit 7 | 0.011 | ||
| Bclaf1 | BCL2-associated transcription factor 1 | 0.011 | ||
| Dtl | denticleless homolog (Drosophila) | 0.011 | ||
| Zscan4b | zinc finger and SCAN domain containing 4B | 0.011 | ||
| Kntc1 | kinetochore associated 1 | 0.011 | ||
| Casp2 | caspase 2 | 0.011 | ||
| Zfp148 | zinc finger protein 148 | 0.011 | ||
| Kif22 | kinesin family member 22 | 0.011 | ||
| Epc1 | enhancer of polycomb homolog 1 (Drosophila) | 0.010 | Human | |
| Kdm1a | lysine (K)-specific demethylase 1A | 0.010 | ||
| Bod1l | biorientation of chromosomes in cell division 1-like | 0.010 | ||
| Chtf18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) | 0.010 | ||
| Eme1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.010 | ||
| Hira | histone cell cycle regulation defective homolog A (S. cerevisiae) | 0.010 | ||
| Ankhd1 | ankyrin repeat and KH domain containing 1 | 0.010 | ||
| Rfc1 | replication factor C (activator 1) 1 | 0.010 |