IMP

Process View

Danio rerio

14 genes annotated in zebrafish

dorsal convergence

The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dorsal convergence"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dorsal convergence" (in gray)

Name	Description	Probability	Func Analog Organism
bmp4	bone morphogenetic protein 4	0.966	Zebrafish
wnt5b	wingless-type MMTV integration site family, member 5b	0.941
wnt4a	wingless-type MMTV integration site family, member 4a	0.936	Zebrafish
tbx1	T-box 1	0.861
wnt10a	wingless-type MMTV integration site family, member 10a	0.774	Zebrafish
bmp2a	bone morphogenetic protein 2a	0.761	Zebrafish
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.757	Zebrafish
wnt9b	wingless-type MMTV integration site family, member 9B	0.676	Zebrafish
twist1a	twist1a	0.570
dkk1b	dickkopf 1b	0.532
bmp2b	bone morphogenetic protein 2b	0.527
ved	ventrally expressed dharma/bozozok antagonist	0.513
wnt3	wingless-type MMTV integration site family, member 3	0.479	Zebrafish
dharma	dharma	0.472
map2k4a	mitogen-activated protein kinase kinase 4a	0.429
spry2	sprouty homolog 2	0.418
nrg2a	neuregulin 2a	0.403
lef1	lymphocyte enhancer binding factor 1	0.403
hhip	hedgehog interacting protein	0.385
wnt10b	wingless-type MMTV integration site family, member 10b	0.383	Zebrafish
igf1rb	insulin-like growth factor 1b receptor	0.369
foxp1b	forkhead box P1b	0.356
ephb4b	eph receptor B4b	0.351
hnf1ba	HNF1 homeobox Ba	0.331
gata5	GATA-binding protein 5	0.313
fgf17	fibroblast growth factor 17	0.302
fbn2b	fibrillin 2b	0.295
foxd5	forkhead box D5	0.294
spns2	spinster homolog 2 (Drosophila)	0.285
smad5	MAD homolog 5 (Drosophila)	0.268
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.254	Zebrafish
wnt11r	wingless-type MMTV integration site family, member 11, related	0.238	Zebrafish
cast	calpastatin	0.229
gro1	groucho 1	0.226
oep	one-eyed pinhead	0.201
fn1	fibronectin 1	0.201
smad9	MAD homolog 9 (Drosophila)	0.193	Zebrafish
plxnb2a	plexin b2a	0.190
mapk3	mitogen-activated protein kinase 3	0.190
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.186	Zebrafish
ctnnb1	catenin (cadherin-associated protein), beta 1	0.185
mapk4	mitogen-activated protein kinase 4	0.184
flh	floating head	0.184
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.183	Zebrafish
msxc	muscle segment homeobox C	0.181
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.178
wnt2	wingless-type MMTV integration site family member 2	0.174	Zebrafish
ntla	no tail a	0.166
hoxd4a	homeo box D4a	0.165
msxb	muscle segment homeobox B	0.156
mapk1	mitogen-activated protein kinase 1	0.155
vent	ventral expressed homeobox	0.153
ccm2	cerebral cavernous malformation 2	0.141
zbtb4	zinc finger and BTB domain containing 4	0.136
tnnt2a	troponin T2a, cardiac	0.129
prickle1a	prickle-like 1 (Drosophila) a	0.129
rnd1l	Rho family GTPase 1 like	0.129
twist3	twist3	0.120
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.119
eve1	even-skipped-like1	0.119
tmem2	transmembrane protein 2	0.117
cdh2	cadherin 2, neuronal	0.116
brd4	bromodomain containing 4	0.115
wnt3a	wingless-type MMTV integration site family, member 3A	0.110	Zebrafish
gro2	groucho 2	0.105
foxa3	forkhead box A3	0.104
rarga	retinoic acid receptor gamma a	0.104
nog1	noggin 1	0.101
fgf3	fibroblast growth factor 3	0.101
snai1b	snail homolog 1b (Drosophila)	0.098
myod1	myogenic differentiation 1	0.088
her5	hairy-related 5	0.088
tbx2a	T-box gene 2a	0.087
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.085
gbx2	gastrulation brain homeo box 2	0.084
per3	period homolog 3 (Drosophila)	0.083
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.080
slit3	slit (Drosophila) homolog 3	0.078
raraa	retinoic acid receptor, alpha a	0.077
pcdh8	protocadherin 8	0.077
snai1a	snail homolog 1a (Drosophila)	0.076
osr1	odd-skipped related 1 (Drosophila)	0.076
tbx16	T-box gene 16	0.075
fbln1	fibulin 1	0.074
pdlim3b	PDZ and LIM domain 3b	0.073
osr2	odd-skipped related 2 (Drosophila)	0.072
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.070	Zebrafish
nkd1	naked cuticle homolog 1 (Drosophila)	0.069
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.069	Zebrafish
wif1	wnt inhibitory factor 1	0.068
itga3b	integrin, alpha 3b	0.066
mapk6	mitogen-activated protein kinase 6	0.065
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.065
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.064
frzb	frizzled-related protein	0.063
cdh6	cadherin 6	0.063
wnt5a	wingless-type MMTV integration site family, member 5a	0.061	Zebrafish
mical3	flavoprotein oxidoreductase MICAL3	0.060
sfrp1b	secreted frizzled-related protein 1b	0.059
wnt16	wingless-type MMTV integration site family, member 16	0.057
map2k4b	mitogen-activated protein kinase kinase 4b	0.056
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.056
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.056
perp	PERP, TP53 apoptosis effector	0.055
gpr126	G protein-coupled receptor 126	0.054
shhb	sonic hedgehog b	0.053
ncor1	nuclear receptor co-repressor 1	0.052
nkd2	naked cuticle homolog 2 and naked 2a	0.052
kdrl	kinase insert domain receptor like	0.052
admp	anti-dorsalizing morphogenic protein	0.051
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.051	Zebrafish
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.049
map2k7	mitogen-activated protein kinase kinase 7	0.049
myf5	myogenic factor 5	0.048
smad1	MAD homolog 1 (Drosophila)	0.048	Zebrafish
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.047
fzd10	frizzled homolog 10	0.047
spry4	sprouty (Drosophila) homolog 4	0.047
dspa	desmoplakin a	0.045
si:ch211-173o4.2	si:ch211-173o4.2	0.045
sema3aa	semaphorin 3aa	0.045
hoxa13b	homeo box A13b	0.044
zfyve26	zinc finger, FYVE domain containing 26	0.044
nrarpa	notch-regulated ankyrin repeat protein a	0.044
boc	brother of CDO	0.044
arhgap29a	Rho GTPase activating protein 29a	0.043
bmp1a	bone morphogenetic protein 1a	0.042
si:dkey-273o13.1	si:dkey-273o13.1	0.042
krit1	KRIT1, ankyrin repeat containing	0.041
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.040
pcdh18a	protocadherin 18a	0.040
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.040
wnt1	wingless-type MMTV integration site family, member 1	0.039	Zebrafish
sox17	SRY-box containing gene 17	0.039
dusp6	dual specificity phosphatase 6	0.038
axin1	axin 1	0.037
emx3	empty spiracles homeobox 3	0.037
skia	nuclear oncoprotein skia	0.037
mapk12	mitogen-activated protein kinase 12	0.037
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.036
ntn1b	netrin 1b	0.035
lft2	lefty2	0.035
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.035
ptk2.1	protein tyrosine kinase 2a	0.035
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.034
epb4.1l4	erythrocyte protein band 4.1-like 4	0.033
hgfa	hepatocyte growth factor a	0.033
itgav	integrin, alpha V	0.033
f2r	coagulation factor II (thrombin) receptor	0.032
foxo3b	forkhead box O3b	0.032
acta2	actin, alpha 2, smooth muscle, aorta	0.032
zgc:193613	zgc:193613	0.032
sfrp1a	secreted frizzled-related protein 1a	0.032
runx3	runt-related transcription factor 3	0.032
fbp1b	fructose-1,6-bisphosphatase 1b	0.031
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.031
wnt11	wingless-type MMTV integration site family, member 11	0.031	Zebrafish
rbfox1l	RNA binding protein, fox-1 homolog (C. elegans) 1-like	0.031
zeb2a	zinc finger E-box binding homeobox 2a	0.031
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.031
hand2	heart and neural crest derivatives expressed transcript 2	0.031
msxd	muscle segment homeobox D	0.031
smo	smoothened homolog (Drosophila)	0.031
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.031
prkci	protein kinase C, iota	0.030
lzts2a	leucine zipper, putative tumor suppressor 2a	0.030
sulf1	sulfatase 1	0.030
klf4a	Kruppel-like transcription factor 4a	0.030
nadl1.2	neural adhesion molecule L1.2	0.030
brd2a	bromodomain-containing 2a	0.030
nrg1	neuregulin 1	0.029
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.029
selp	selectin P	0.029
szl	sizzled	0.028
bon	bonnie and clyde	0.028
col11a2	collagen type XI alpha-2	0.028
pax7a	paired box gene 7a	0.028
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.028	Zebrafish
tgfb1a	transforming growth factor, beta 1a	0.028
lhx2b	LIM homeobox 2b	0.028
pkd2	polycystic kidney disease 2	0.027
igf1ra	insulin-like growth factor 1a receptor	0.027
tp63	tumor protein p63	0.027
siah2l	seven in absentia homolog 2 (Drosophila)-like	0.027
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.027
ldb2a	LIM-domain binding factor 2a	0.027
runx2b	runt-related transcription factor 2b	0.027
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.026
LOC566708	FL cytokine receptor-like	0.026
tbx6	T-box gene 6	0.026
oprm1	opioid receptor, mu 1	0.025
mespb	mesoderm posterior b	0.025
csnk1da	casein kinase 1, delta a	0.025
htra1a	HtrA serine peptidase 1a	0.024
tbx20	T-box 20	0.024
notum3	notum 3	0.024
mmp2	matrix metalloproteinase 2	0.024
lox	lysyl oxidase	0.024
vox	ventral homeobox	0.023
p4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2	0.023
fmnl2a	formin-like 2a	0.023
hspa12b	heat shock protein 12B	0.023
plcg1	phospholipase C, gamma 1	0.023
rnd3a	Rho family GTPase 3a	0.023
stat1b	signal transducer and activator of transcription 1b	0.023
slit2	slit (Drosophila) homolog 2	0.023
antxr2a	anthrax toxin receptor 2a	0.023
bmp16	bone morphogenetic protein 16	0.022
gata2a	GATA-binding protein 2a	0.022
ptpra	protein tyrosine phosphatase, receptor type, A	0.022
met	met proto-oncogene (hepatocyte growth factor receptor)	0.022
metrn	meteorin, glial cell differentiation regulator	0.022
zgc:194131	zgc:194131	0.022
igfbp3	insulin-like growth factor binding protein 3	0.021
cdx4	caudal type homeo box transcription factor 4	0.021
mapk8b	mitogen-activated protein kinase 8b	0.021
chd	chordin	0.021
ndr2	nodal-related 2	0.021
apoa1	apolipoprotein A-I	0.021
vhl	von Hippel-Lindau tumor suppressor	0.021
frem2a	Fras1 related extracellular matrix protein 2a	0.020
bhlhe41	basic helix-loop-helix family, member e41	0.020
dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.020
klf4	Kruppel-like factor 4	0.020
tbx2b	T-box 2b	0.020
gfra1a	gdnf family receptor alpha 1a	0.020
zgc:112211	zgc:112211	0.019
mapk7	mitogen-activated protein kinase 7	0.019
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.019
slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.019
ext1a	exostoses (multiple) 1a	0.019
fgf4	fibroblast growth factor 4	0.019
gyltl1b	glycosyltransferase-like 1b	0.019
igf2a	insulin-like growth factor 2a	0.019
sox19b	SRY-box containing gene 19b	0.019
znf503	zinc finger protein 503	0.019
foxa2	forkhead box A2	0.019
mos	v-mos Moloney murine sarcoma viral oncogene homolog	0.019
podxl	podocalyxin-like	0.019
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.018
tll1	tolloid-like 1	0.018
sdc2	syndecan 2	0.018
lft1	lefty1	0.018
si:dkey-236e20.2	si:dkey-236e20.2	0.018
aplnrb	apelin receptor b	0.018
cenph	centromere protein H	0.018
egr1	early growth response 1	0.018
wls	wntless homolog (Drosophila)	0.018
lama5	laminin, alpha 5	0.017
ntn2	netrin 2	0.017
evx1	even-skipped homeobox 1	0.017
efnb1	ephrin B1	0.017
sox32	SRY-box containing gene 32	0.017
efnb2a	ephrin B2a	0.017
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.017
fzd9b	frizzled homolog 9b	0.016
ca15b	carbonic anhydrase XV b	0.016
glceb	glucuronyl C5-epimerase b	0.016
npnt	nephronectin	0.016
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.016
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.016
frem1a	Fras1 related extracellular matrix 1a	0.016
jam2a	junctional adhesion molecule 2a	0.016
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.016
ltbp3	latent transforming growth factor beta binding protein 3	0.016
nkx2.5	NK2 transcription factor related 5	0.016
fzd5	frizzled homolog 5	0.016
ckap5	cytoskeleton associated protein 5	0.016
thrb	thyroid hormone receptor beta	0.016
her3	hairy-related 3	0.016
atoh8	atonal homolog 8	0.016
wtip	Wilms tumor 1 interacting protein	0.016
rasl11b	RAS-like, family 11, member B	0.016
mapk14a	mitogen-activated protein kinase 14a	0.015
sept7b	septin 7b	0.015
mastl	microtubule associated serine/threonine kinase-like	0.015
dld	deltaD	0.015
zgc:171495	zgc:171495	0.015
txlnba	taxilin beta a	0.015
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.015
syk	spleen tyrosine kinase	0.015
bty	bloodthirsty	0.015
jag2	jagged 2	0.015
ripply1	ripply1	0.015
ism1	isthmin 1	0.015
foxd3	forkhead box D3	0.015
irgq1	immunity-related GTPase family, q1	0.015
dlx3b	distal-less homeobox gene 3b	0.014
bmp3	bone morphogenetic protein 3	0.014
a2ml	alpha-2-macroglobulin-like	0.014
fgfr4	fibroblast growth factor receptor 4	0.014
rasgrp3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	0.014
krt18	keratin 18	0.014
antxr1	anthrax toxin receptor 1	0.014
zgc:66242	zgc:66242	0.014
lama4	laminin, alpha 4	0.014
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.014
LOC100359374	BCL-WAV	0.014
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.014
csnk1g2a	casein kinase 1, gamma 2a	0.014
runx1	runt-related transcription factor 1	0.014
mmp15a	matrix metallopeptidase 15a	0.014
myh10	myosin, heavy polypeptide 10, non-muscle and myosin, heavy chain 10, non-muscle	0.013
igf2b	insulin-like growth factor 2b	0.013
igfbp5a	insulin-like growth factor binding protein 5a	0.013
im:7165141	im:7165141	0.013
supt6h	suppressor of Ty 6 homolog	0.013
fgf24	fibroblast growth factor 24	0.013
kop	askopos	0.013
aplp2	amyloid beta (A4) precursor-like protein 2	0.013
sh3gl1b	SH3-domain GRB2-like 1b	0.013
efna3b	ephrin A3b	0.013
ppp4cb	protein phosphatase 4 (formerly X), catalytic subunit b	0.013
appa	amyloid beta (A4) precursor protein a	0.013
fabp2	fatty acid binding protein 2, intestinal	0.013
dsg2	desmoglein 2	0.013
lhx1b	LIM homeobox 1b	0.013
prickle2	prickle-like 2 (Drosophila)	0.013
lamb1a	laminin, beta 1a	0.012
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.012
rhov	ras homolog gene family, member V	0.012
bmp7a	bone morphogenetic protein 7a	0.012
id:ibd2050	id:ibd2050	0.012
ptmab	prothymosin, alpha b	0.012
ift46	intraflagellar transport protein 46	0.012
cx44.2	connexin 44.2	0.012
dusp4	dual specificity phosphatase 4	0.012
hmx4	H6 family homeobox 4	0.012
lpp	LIM domain containing preferred translocation partner in lipoma	0.012
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.012
arl4ab	ADP-ribosylation factor-like 4ab	0.012
si:ch73-60e21.1	si:ch73-60e21.1	0.012
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.012
and1	actinodin1	0.012
sp5l	Sp5 transcription factor-like	0.011
hoxc6a	homeo box C6a	0.011
zgc:123296	zgc:123296	0.011
ppp1r3ca	protein phosphatase 1, regulatory (inhibitor) subunit 3Ca	0.011
zmynd11	zinc finger, MYND domain containing 11	0.011
fyna	FYN oncogene related to SRC, FGR, YES a	0.011
six4b	sine oculis homeobox homolog 4b	0.011
spon2a	spondin 2a, extracellular matrix protein	0.011
igf1	insulin-like growth factor 1	0.011
synpo2lb	synaptopodin 2-like b	0.011
ripply2	ripply2	0.011
araf	v-raf murine sarcoma 3611 viral oncogene homolog	0.011
zgc:100933	zgc:100933	0.011
LOC572344	hypothetical protein LOC572344	0.011
thop1	thimet oligopeptidase 1	0.011
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.011
klf2a	Kruppel-like factor 2a	0.011
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.011
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.011
ier2	immediate early response 2	0.011
LOC567965	rho GTPase-activating protein 7-like	0.011
fas	Fas (TNF receptor superfamily, member 6)	0.011
sb:cb81	sb:cb81	0.011
foxj1a	forkhead box J1a	0.011
eng1a	engrailed 1a	0.011
wu:fj62d01	wu:fj62d01	0.011
max	myc-associated factor X	0.010
hoxd11a	homeo box D11a	0.010
si:ch1073-351m12.1	si:ch1073-351m12.1	0.010
rbp4	retinol binding protein 4, plasma	0.010
smad6a	SMAD family member 6a	0.010	Zebrafish
gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.010
csk	c-src tyrosine kinase	0.010
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.010
ptk2.2	protein tyrosine kinase 2b	0.010
tcf21	transcription factor 21	0.010
aplnra	apelin receptor a	0.010
pla2g12b	phospholipase A2, group XIIB	0.010
hoxa13a	homeo box A13a	0.010
ndr1	nodal-related 1	0.010
nnr	nanor	0.010
mespa	mesoderm posterior a	0.010
celf1	cugbp, Elav-like family member 1	0.010