IMP

Process View

Danio rerio

22 genes annotated in zebrafish

fibroblast growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "fibroblast growth factor receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "fibroblast growth factor receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
fgf3	fibroblast growth factor 3	0.879	Mouse Worm
twist3	twist3	0.424
wnt8b	wingless-type MMTV integration site family, member 8b	0.422	Zebrafish
dlx5a	distal-less homeobox gene 5a	0.416
chd	chordin	0.411
tbx1	T-box 1	0.402
wnt4a	wingless-type MMTV integration site family, member 4a	0.297	Zebrafish Mouse
fgf17	fibroblast growth factor 17	0.291	Mouse
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.279
ptch2	patched 2	0.278
robo3	roundabout homolog 3	0.261
cdx1b	caudal type homeobox 1 b	0.202
dharma	dharma	0.199
bmp4	bone morphogenetic protein 4	0.179
spry4	sprouty (Drosophila) homolog 4	0.176
dusp6	dual specificity phosphatase 6	0.173
wnt1	wingless-type MMTV integration site family, member 1	0.159	Zebrafish
wnt10a	wingless-type MMTV integration site family, member 10a	0.139	Zebrafish
sulf1	sulfatase 1	0.126	Human Mouse
wnt5b	wingless-type MMTV integration site family, member 5b	0.115	Zebrafish Mouse
bmp2a	bone morphogenetic protein 2a	0.102
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.099
fzd7a	frizzled homolog 7a	0.099
bmp2b	bone morphogenetic protein 2b	0.097
ndr1	nodal-related 1	0.095
foxa2	forkhead box A2	0.093
flh	floating head	0.091
spns2	spinster homolog 2 (Drosophila)	0.089
etv5a	ets variant 5a	0.088
dkk1b	dickkopf 1b	0.086
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.086
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.083
wnt9a	wingless-type MMTV integration site family, member 9A	0.078	Zebrafish
lft1	lefty1	0.077
smad9	MAD homolog 9 (Drosophila)	0.075
wnt3a	wingless-type MMTV integration site family, member 3A	0.075	Zebrafish
wif1	wnt inhibitory factor 1	0.071
bmp1a	bone morphogenetic protein 1a	0.066
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.065
pea3	ETS-domain transcription factor pea3	0.061
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.059
fgf4	fibroblast growth factor 4	0.059	Human Mouse Worm
zbtb4	zinc finger and BTB domain containing 4	0.057
bon	bonnie and clyde	0.055
wnt10b	wingless-type MMTV integration site family, member 10b	0.053	Zebrafish
ephb4b	eph receptor B4b	0.052
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.051
tbx2b	T-box 2b	0.051
brd4	bromodomain containing 4	0.049
shha	sonic hedgehog a	0.049	Fly
twist1b	twist1b	0.048
gata2a	GATA-binding protein 2a	0.047	Zebrafish
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.044
lft2	lefty2	0.044
smox	spermine oxidase	0.044
sec24d	SEC24 family, member D (S. cerevisiae)	0.044
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.044
fgf8a	fibroblast growth factor 8 a	0.044	Mouse
wnt2	wingless-type MMTV integration site family member 2	0.043	Zebrafish
foxd3	forkhead box D3	0.043
emx3	empty spiracles homeobox 3	0.042
fn1	fibronectin 1	0.041
foxa1	forkhead box A1	0.041
ihha	Indian hedgehog homolog a	0.040	Fly
aplnrb	apelin receptor b	0.040
wnt3	wingless-type MMTV integration site family, member 3	0.040	Zebrafish
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.039	Zebrafish
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.039
lef1	lymphocyte enhancer binding factor 1	0.038
sfrp1a	secreted frizzled-related protein 1a	0.038
runx2b	runt-related transcription factor 2b	0.037	Mouse
mmp15b	matrix metallopeptidase 15b	0.037
og9x	OG9 homeobox gene	0.037
boc	brother of CDO	0.037
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.037
si:dkey-273o13.1	si:dkey-273o13.1	0.036
runx3	runt-related transcription factor 3	0.036
wnt9b	wingless-type MMTV integration site family, member 9B	0.035	Zebrafish
grhl2b	grainyhead-like 2b (Drosophila)	0.035
frzb	frizzled-related protein	0.035
pcdh8	protocadherin 8	0.034
gli2a	GLI-Kruppel family member GLI2a	0.034
gpc4	glypican 4	0.033
spon2a	spondin 2a, extracellular matrix protein	0.033
wnt5a	wingless-type MMTV integration site family, member 5a	0.033	Zebrafish
col5a1	procollagen, type V, alpha 1	0.033
vax1	ventral anterior homeobox 1	0.033
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.032
meis2.2	myeloid ecotropic viral integration site 2.2	0.032
ntla	no tail a	0.031
hmx4	H6 family homeobox 4	0.031
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.031
sulf2l	sulfatase 2, like	0.031	Mouse
notum3	notum 3	0.030
klf4	Kruppel-like factor 4	0.030
sfrp5	secreted frizzled-related protein 5	0.030
col11a2	collagen type XI alpha-2	0.030
hoxd4a	homeo box D4a	0.029
vent	ventral expressed homeobox	0.029
wls	wntless homolog (Drosophila)	0.029
pou5f1	POU domain, class 5, transcription factor 1	0.029
fzd10	frizzled homolog 10	0.029
tob1a	transducer of ERBB2, 1a	0.029
efnb2a	ephrin B2a	0.027
zfand5a	zinc finger, AN1-type domain 5a	0.027
gbx2	gastrulation brain homeo box 2	0.027
hmx1	H6 homeo box 1	0.026
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.026
runx2a	runt-related transcription factor 2a	0.026	Mouse
gnb1b	guanine nucleotide binding protein (G protein), beta polypeptide 1b	0.026
wnt16	wingless-type MMTV integration site family, member 16	0.026
sall1a	sal-like 1a (Drosophila)	0.026
znf711	zinc finger protein 711	0.026
lhx2b	LIM homeobox 2b	0.026
nog2	noggin 2	0.025
metrn	meteorin, glial cell differentiation regulator	0.025
extl3	exostoses (multiple)-like 3	0.025
nog1	noggin 1	0.025	Human
mapk1	mitogen-activated protein kinase 1	0.025
axin1	axin 1	0.025
LOC559454	glypican-5-like	0.025
etv2	ets variant gene 2	0.025
col11a1a	collagen, type XI, alpha 1a	0.025
mc5rb	melanocortin 5b receptor	0.024
msxd	muscle segment homeobox D	0.024
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.024
gro2	groucho 2	0.024
mapk3	mitogen-activated protein kinase 3	0.024
btg2	B-cell translocation gene 2	0.024
ptena	phosphatase and tensin homolog A	0.024
ism1	isthmin 1	0.024
eve1	even-skipped-like1	0.023
atoh1a	atonal homolog 1a	0.023
jag1b	jagged 1b	0.023
nadl1.1	neural adhesion molecule L1.1	0.023
zgc:63947	zgc:63947	0.023
sfrp1b	secreted frizzled-related protein 1b	0.022
eng1a	engrailed 1a	0.022
optc	opticin	0.022
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.022
dusp4	dual specificity phosphatase 4	0.022	Zebrafish
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.022
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.022
pcdh18a	protocadherin 18a	0.022
prickle1a	prickle-like 1 (Drosophila) a	0.021
robo1	roundabout homolog 1	0.021
vwa2	von Willebrand factor A domain containing 2	0.021
arl4ab	ADP-ribosylation factor-like 4ab	0.021
bmper	BMP binding endothelial regulator	0.021
tgfb3	transforming growth factor, beta 3	0.021
hand2	heart and neural crest derivatives expressed transcript 2	0.021
mecom	MDS1 and EVI1 complex locus	0.021
msxc	muscle segment homeobox C	0.021
notch3	notch homolog 3	0.021
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.021
dld	deltaD	0.021
lfng	lunatic fringe homolog	0.021
col8a1a	collagen, type VIII, alpha 1a	0.020
gli1	GLI-Kruppel family member 1	0.020
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.020
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.020
csnk1db	casein kinase 1, delta b	0.020
LOC100536647	disintegrin and metalloproteinase domain-containing protein 10-like	0.020
fzd7b	frizzled homolog 7b	0.020
zgc:165373	zgc:165373	0.020
cfl2l	cofilin 2, like	0.020
pigu	phosphatidylinositol glycan anchor biosynthesis, class U	0.019
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.019	Zebrafish
lama5	laminin, alpha 5	0.019
zfyve26	zinc finger, FYVE domain containing 26	0.019
hes6	hairy and enhancer of split 6 (Drosophila)	0.019
LOC556647	GDNF family receptor alpha-4-like	0.019
ryk	receptor-like tyrosine kinase	0.019
mbtps1	membrane-bound transcription factor protease, site 1	0.018
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.018
map2k4a	mitogen-activated protein kinase kinase 4a	0.018
irx3a	iroquois homeobox protein 3a	0.018
hapln3	hyaluronan and proteoglycan link protein 3	0.018
etv5b	ets variant 5b	0.018
axin2	axin 2 (conductin, axil)	0.018
fgf24	fibroblast growth factor 24	0.018
csnk1da	casein kinase 1, delta a	0.017
fzd8b	frizzled homolog 8b	0.017
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.017
sfrp2	secreted frizzled-related protein 2	0.017
zgc:100906	zgc:100906	0.017
sulf2	sulfatase 2	0.017	Mouse
pcdh19	protocadherin 19	0.017
epha4b	eph receptor A4b	0.017
mecp2	methyl CpG binding protein 2	0.017
fibpl	fibroblast growth factor (acidic) intracellular binding protein, like	0.017
sp9	sp9 transcription factor	0.017
plagl2	pleiomorphic adenoma gene-like 2	0.016
zgc:158603	zgc:158603	0.016
gata4	GATA-binding protein 4	0.016	Zebrafish
f2rl1.1	coagulation factor II (thrombin) receptor-like 1.1	0.016
hhip	hedgehog interacting protein	0.016	Mouse
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.016
cdh2	cadherin 2, neuronal	0.016
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.016
ncor1	nuclear receptor co-repressor 1	0.016
mib	mind bomb	0.016
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.016
ahr2	aryl hydrocarbon receptor 2	0.016
scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.016
pth2r	parathyroid hormone 2 receptor	0.016
hoxa13b	homeo box A13b	0.016
gli3	GLI-Kruppel family member GLI3	0.016
soul4	heme-binding protein soul4	0.015
glra1	glycine receptor, alpha 1	0.015
col2a1a	collagen type II, alpha-1a	0.015
zgc:101614	zgc:101614	0.015
notch2	notch homolog 2	0.015
spry2	sprouty homolog 2	0.015
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.015
per2	period homolog 2 (Drosophila)	0.015
shox2	short stature homeobox 2	0.015
cpa4	carboxypeptidase A4	0.015
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.015
gmnn	geminin, DNA replication inhibitor	0.015
htra1a	HtrA serine peptidase 1a	0.015
lbx1a	ladybird homeobox 1a	0.015
rasl11b	RAS-like, family 11, member B	0.015
si:ch211-57k11.10	si:ch211-57k11.10	0.015
pomca	proopiomelanocortin a	0.014
lrmp	lymphoid-restricted membrane protein	0.014
cpa2	carboxypeptidase A2 (pancreatic)	0.014
mapk6	mitogen-activated protein kinase 6	0.014
csnk1g2a	casein kinase 1, gamma 2a	0.014
map2k7	mitogen-activated protein kinase kinase 7	0.014
slc38a2	solute carrier family 38, member 2	0.014
gro1	groucho 1	0.014
mapk12	mitogen-activated protein kinase 12	0.014
atp1a3al	ATPase, Na+/K+ transporting, alpha 3a polypeptide, like	0.014
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.014
sb:cb81	sb:cb81	0.014
sox2	SRY-box containing gene 2	0.014
btbd6a	BTB (POZ) domain containing 6a	0.014
ier2	immediate early response 2	0.014
oprd1a	opioid receptor, delta 1a	0.014
onecutl	one cut domain, family member, like	0.014
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.014
msxa	muscle segment homeobox A	0.014
disp1	dispatched homolog 1 (Drosophila)	0.014
csk	c-src tyrosine kinase	0.014
junbl	jun B proto-oncogene, like	0.014
igf1rb	insulin-like growth factor 1b receptor	0.013
fli1a	friend leukemia integration 1a	0.013
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.013
fgf18a	fibroblast growth factor 18a	0.013
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.013
fgf22	fibroblast growth factor 22	0.013
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.013
im:7151712	im:7151712	0.013
odz4	odd Oz/ten-m homolog 4	0.013
nnr	nanor	0.013
msxb	muscle segment homeobox B	0.013
pbx4	pre-B-cell leukemia transcription factor 4	0.013
cpsf6	cleavage and polyadenylation specific factor 6	0.013
fosl2	fos-like antigen 2	0.013
midn	midnolin	0.013
vox	ventral homeobox	0.013
stap2a	signal transducing adaptor family member 2a	0.013
nkx2.5	NK2 transcription factor related 5	0.013
ext2	exostoses (multiple) 2	0.013
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.013
foxa3	forkhead box A3	0.013
ephb3a	eph receptor B3a	0.013
nrarpa	notch-regulated ankyrin repeat protein a	0.013
otpa	orthopedia homolog a	0.013
admp	anti-dorsalizing morphogenic protein	0.013
tal1	T-cell acute lymphocytic leukemia 1	0.013
tsen54	tRNA splicing endonuclease 54 homolog (S. cerevisiae)	0.013
ptch1	patched 1	0.013
apc	adenomatosis polyposis coli	0.013
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.012
smo	smoothened homolog (Drosophila)	0.012
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.012
dacha	dachshund a	0.012
oep	one-eyed pinhead	0.012
otomp	otolith matrix protein	0.012
unc45a	unc-45 homolog A (C. elegans)	0.012
ret1	receptor tyrosine kinase	0.012
has3	hyaluronan synthase 3	0.012
junb	jun B proto-oncogene	0.012
barx2	BarH-like homeobox 2	0.012
alas2	aminolevulinate, delta-, synthetase 2	0.012
col9a3	collagen, type IX, alpha 3	0.012
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.012	Zebrafish
nkx3.2	NK3 homeobox 2	0.012
slc35b2	solute carrier family 35, member B2	0.012
esrrgb	estrogen-related receptor gamma b	0.012
si:dkey-235k4.1	si:dkey-235k4.1	0.012
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.012
dpysl5a	dihydropyrimidinase-like 5a	0.012
amotl2a	angiomotin like 2a	0.012
pax2b	paired box gene 2b	0.012
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.012
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.012
tacc2	transforming, acidic coiled-coil containing protein 2	0.012
gle1	GLE1 RNA export mediator homolog (yeast)	0.011
pdgfaa	platelet-derived growth factor alpha a	0.011
pax8	paired box gene 8	0.011
stat1b	signal transducer and activator of transcription 1b	0.011
hmx2	H6 family homeobox 2	0.011
spry1	sprouty homolog 1 (Drosophila)	0.011
cep55l	centrosomal protein 55 like	0.011
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.011
kif5ba	kinesin family member 5B, a	0.011
mapk7	mitogen-activated protein kinase 7	0.011
lrrc6	leucine rich repeat containing 6	0.011
sppl3	signal peptide peptidase 3	0.011
col5a3	collagen, type V, alpha 3	0.011
runx1	runt-related transcription factor 1	0.011
msnb	moesin b	0.011
mapk8b	mitogen-activated protein kinase 8b	0.011
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.011
coro1b	coronin, actin binding protein, 1B	0.011
pggt1b	protein geranylgeranyltransferase type I, beta subunit	0.011
trim24	tripartite motif-containing 24	0.011
dcst2	DC-STAMP domain containing 2	0.011
cited3	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3	0.011
patl1	protein associated with topoisomerase II homolog 1 (yeast)	0.011
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.011
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.011
mknk2b	MAP kinase-interacting serine/threonine kinase 2b	0.011
osr2	odd-skipped related 2 (Drosophila)	0.011
fgf8b	fibroblast growth factor 8 b	0.011	Human Mouse
oprm1	opioid receptor, mu 1	0.011
pcdh10b	protocadherin 10b	0.011
heyl	hairy/enhancer-of-split related with YRPW motif-like	0.011
tdh	L-threonine dehydrogenase	0.011
fgf16	fibroblast growth factor 16	0.011	Rat Worm
col11a1b	collagen type XI alpha-1b and collagen, type XI, alpha 1b	0.011
lhx6	LIM homeobox 6	0.011
otx1b	orthodenticle homolog 1b	0.011
appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.011
k31	k31 gene	0.011
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.011
sh2d3cb	SH2 domain containing 3Cb	0.011
mycbp2	MYC binding protein 2	0.011
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.011
snai1b	snail homolog 1b (Drosophila)	0.011
csdc2	cold shock domain containing C2, RNA binding	0.011
wnt11	wingless-type MMTV integration site family, member 11	0.011	Zebrafish
sb:cb322	sb:cb322	0.011
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.011
plekhg4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	0.011
nkd2	naked cuticle homolog 2 and naked 2a	0.011
hhex	hematopoietically expressed homeobox	0.011
esr2a	estrogen receptor 2a	0.010
pbxip1b	pre-B-cell leukemia homeobox interacting protein 1b	0.010
vcana	versican a	0.010
phf8	PHD finger protein 8	0.010
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.010
lmo3	LIM domain only 3	0.010
znf703	zinc finger protein 703	0.010
rc3	rabconnectin 3	0.010
igfbp3	insulin-like growth factor binding protein 3	0.010
utx	ubiquitously transcribed tetratricopeptide repeat, X chromosome	0.010
sec61al1	Sec61 alpha like 1	0.010
hoxa2b	homeo box A2b	0.010
bmp7b	bone morphogenetic protein 7b	0.010
foxc1b	forkhead box C1b	0.010
tp73	tumor protein p73	0.010
pdlim3b	PDZ and LIM domain 3b	0.010
glceb	glucuronyl C5-epimerase b	0.010