Process View
The network for 'regulation of fever generation by regulation of prostaglandin secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tnf | tumor necrosis factor | 0.997 | |
| Lta | lymphotoxin A | 0.982 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.973 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.963 | |
| Ifng | interferon gamma | 0.893 | |
| Il10 | interleukin 10 | 0.846 | |
| Ltb | lymphotoxin B | 0.640 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.499 | |
| Cd19 | CD19 antigen | 0.474 | |
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.284 | |
| Cd40 | CD40 antigen | 0.173 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.172 | |
| Il7 | interleukin 7 | 0.161 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.110 | |
| Il4 | interleukin 4 | 0.107 | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.105 | |
| Il6 | interleukin 6 | 0.101 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.080 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.076 | |
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.073 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.064 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.063 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.059 | |
| Igh | immunoglobulin heavy chain complex | 0.051 | |
| Gpr132 | G protein-coupled receptor 132 | 0.051 | |
| Tox | thymocyte selection-associated high mobility group box | 0.049 | |
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.042 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.041 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.038 | |
| Icos | inducible T-cell co-stimulator | 0.035 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.034 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.034 | |
| Cd40lg | CD40 ligand | 0.034 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.033 | |
| Il1r1 | interleukin 1 receptor, type I | 0.030 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.027 | |
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.026 | |
| Traf6 | TNF receptor-associated factor 6 | 0.026 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.025 | |
| Il2 | interleukin 2 | 0.024 | |
| Il1b | interleukin 1 beta | 0.024 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.021 | |
| Il1rn | interleukin 1 receptor antagonist | 0.020 | |
| Traf2 | TNF receptor-associated factor 2 | 0.020 | |
| Tlr4 | toll-like receptor 4 | 0.020 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.020 | |
| Irg1 | immunoresponsive gene 1 | 0.019 | |
| Il2rg | interleukin 2 receptor, gamma chain | 0.018 | |
| Il12b | interleukin 12b | 0.017 | |
| Ubd | ubiquitin D | 0.017 | |
| Spp1 | secreted phosphoprotein 1 | 0.016 | |
| Rel | reticuloendotheliosis oncogene | 0.015 | |
| Prf1 | perforin 1 (pore forming protein) | 0.015 | |
| Ikbkg | inhibitor of kappaB kinase gamma | 0.014 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.014 | |
| Cd28 | CD28 antigen | 0.014 | |
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.014 | |
| Gzmb | granzyme B | 0.014 | |
| Pdcd1 | programmed cell death 1 | 0.013 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.013 | |
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.013 | |
| Cd160 | CD160 antigen | 0.012 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.012 | |
| Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.012 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.012 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.011 | |
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.011 | |
| Itk | IL2-inducible T-cell kinase | 0.011 | |
| Tnfsf8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.011 | |
| Cd80 | CD80 antigen | 0.010 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.010 |