IMP

Process View

Drosophila melanogaster

12 genes annotated in fly

neuron fate specification

The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neuron fate specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neuron fate specification" (in gray)

Name	Description	Probability	Func Analog Organism
ato	atonal	1.000	Mouse
eyg	eyegone	0.943	Fly
en	engrailed	0.913
ac	achaete	0.880	Mouse
E(spl)	Enhancer of split	0.862
eya	eyes absent	0.811	Mouse
amos	absent MD neurons and olfactory sensilla	0.795	Mouse
HLHm7	E(spl) region transcript m7	0.792
hh	hedgehog	0.747	Zebrafish
ey	eyeless	0.643
wg	wingless	0.612
malpha	E(spl) region transcript malpha	0.585
ro	rough	0.545
Dll	Distal-less	0.539	Zebrafish
Ser	Serrate	0.530
gsb	gooseberry	0.509
Poxn	Pox neuro	0.503	Fly
HGTX	CG13475 gene product from transcript CG13475-RB	0.502
m4	E(spl) region transcript m4	0.496
B-H2	BarH2	0.470
so	sine oculis	0.381	Mouse
sens	senseless	0.376
oc	ocelliless	0.350	Worm
ptc	patched	0.349
yki	yorkie	0.347
beat-Ia	beaten path Ia	0.339
tutl	turtle	0.331
hpo	hippo	0.330
Notum	CG13076 gene product from transcript CG13076-RB	0.317
bib	big brain	0.315
gcm	glial cells missing	0.308
HLHm5	E(spl) region transcript m5	0.296
jeb	jelly belly	0.276
ci	cubitus interruptus	0.263	Zebrafish Mouse
lz	lozenge	0.262
sim	single-minded	0.234
pb	proboscipedia	0.229
lbe	ladybird early	0.227	Mouse
Dfd	Deformed	0.218
HLHmgamma	E(spl) region transcript mgamma	0.213
lbl	ladybird late	0.210	Mouse
slp2	sloppy paired 2	0.210
HLHmdelta	E(spl) region transcript mdelta	0.208
lea	leak	0.205
prd	paired	0.204
Kr	Kruppel	0.201
nub	nubbin	0.188
Abd-B	Abdominal B	0.182
run	runt	0.181
ems	empty spiracles	0.181
nkd	naked cuticle	0.175
toy	twin of eyeless	0.165	Mouse Fly
slp1	sloppy paired 1	0.163	Worm
eve	even skipped	0.160
Antp	Antennapedia	0.150
comm	commissureless	0.147
disco	disconnected	0.139
dac	dachshund	0.136
mam	mastermind	0.135
Tom	Twin of m4	0.134
klu	klumpfuss	0.129
hth	homothorax	0.126
ss	spineless	0.118
sv	shaven	0.112
ase	asense	0.112	Mouse
bchs	blue cheese	0.109
al	aristaless	0.105
Wnt4	Wnt oncogene analog 4	0.095
sbb	scribbler	0.095
sli	slit	0.088
NetB	Netrin-B	0.083	Zebrafish
org-1	optomotor-blind-related-gene-1	0.082
Ubx	Ultrabithorax	0.081
vvl	ventral veins lacking	0.073
sc	scute	0.071	Mouse
fred	friend of echinoid	0.069
HLHmbeta	E(spl) region transcript mbeta	0.069
abd-A	abdominal A	0.069
ara	araucan	0.068
bab2	CG9102 gene product from transcript CG9102-RA	0.068
Optix	CG18455 gene product from transcript CG18455-RA	0.065
ed	echinoid	0.061
mxc	multi sex combs	0.049
arr	arrow	0.048
Lim1	CG11354 gene product from transcript CG11354-RA	0.048
Snr1	Snf5-related 1	0.048
bab1	bric a brac 1	0.045
kni	knirps	0.044
phyl	phyllopod	0.043
kibra	kibra ortholog	0.043
Cdk4	Cyclin-dependent kinase 4	0.040
dy	dusky	0.040
HLHm3	E(spl) region transcript m3	0.039
tld	tolloid	0.038
nab	CG33545 gene product from transcript CG33545-RC	0.037
argos	CG4531 gene product from transcript CG4531-RA	0.037
brk	brinker	0.037
dan	distal antenna	0.037
opa	odd paired	0.036	Worm
Su(H)	Suppressor of Hairless	0.036
sca	scabrous	0.035
m2	E(spl) region transcript m2	0.034
jub	Ajuba LIM protein	0.034
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.034
caup	caupolican	0.033
pnr	pannier	0.033
spdo	sanpodo	0.031
tll	tailless	0.030
ft	fat	0.030
trn	tartan	0.030
dally	division abnormally delayed	0.028
slou	slouch	0.027
btd	buttonhead	0.026
tin	tinman	0.026
odd	odd skipped	0.026
beat-Ic	beaten path Ic	0.024
Doc2	Dorsocross2	0.024
Hcf	Host cell factor	0.023
dlp	dally-like	0.023
byn	brachyenteron	0.023
lab	labial	0.022
crb	crumbs	0.021
mtt	mangetout	0.020
gsb-n	gooseberry-neuro	0.020
kn	knot	0.020
inv	invected	0.019
Dip1	Dorsal interacting protein 1	0.019
danr	distal antenna-related	0.018
pasha	partner of drosha	0.018
B-H1	BarH1	0.018
Eip93F	CG18389 gene product from transcript CG18389-RB	0.017
kuz	kuzbanian	0.017
side	sidestep	0.017
spo	spook	0.017
wts	warts	0.016
mid	midline	0.016
Gsc	Goosecoid	0.016
JhI-1	Juvenile hormone-inducible protein 1	0.016
hbs	hibris	0.016
Fas3	Fasciclin 3	0.016
dpn	deadpan	0.015
grim	CG4345 gene product from transcript CG4345-RA	0.015
lin	lines	0.015
SoxN	SoxNeuro	0.014
CG16813	CG16813 gene product from transcript CG16813-RA	0.014
elav	embryonic lethal abnormal vision	0.014
pdm2	POU domain protein 2	0.014
CycD	Cyclin D	0.014
grn	grain	0.014
vnd	ventral nervous system defective	0.014
noc	no ocelli	0.013
Wnt2	Wnt oncogene analog 2	0.013
sob	sister of odd and bowl	0.013
nvy	nervy	0.013
Poxm	Pox meso	0.013	Fly
wor	worniu	0.013
tup	tailup	0.013	Zebrafish Mouse
hdc	headcase	0.013
robo	roundabout	0.013
m6	E(spl) region transcript m6	0.013
Pvf2	PDGF- and VEGF-related factor 2	0.013
ru	roughoid	0.013
toe	twin of eyg	0.013	Fly
bw	brown	0.012
Wnt6	CG4969 gene product from transcript CG4969-RB	0.012
Awh	Arrowhead	0.012
NT1	Neurotrophin 1	0.012
Tollo	CG6890 gene product from transcript CG6890-RA	0.012
drm	drumstick	0.012
HLH4C	Helix loop helix protein 4C	0.012
otk	off-track	0.012
Actbeta	Activin-beta	0.012
ash2	absent, small, or homeotic discs 2	0.012
Rbf	Retinoblastoma-family protein	0.011
Pten	CG5671 gene product from transcript CG5671-RB	0.011
mas	masquerade	0.011
Pka-C1	cAMP-dependent protein kinase 1	0.011
aop	anterior open	0.011
exex	extra-extra	0.011	Zebrafish Mouse
mira	miranda	0.011
vav	CG7893 gene product from transcript CG7893-RB	0.011
CG10741	CG10741 gene product from transcript CG10741-RB	0.011
btl	breathless	0.011
bin	biniou	0.011
Hph	HIF prolyl hydroxylase	0.011
gt	giant	0.010
twi	twist	0.010
CadN	Cadherin-N	0.010
Psn	Presenilin	0.010
sll	slalom	0.010
CG13287	CG13287 gene product from transcript CG13287-RA	0.010