IMP

Process View

Homo sapiens

20 genes annotated in human

response to hexose

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to hexose"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to hexose" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.622
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.580
PLAUR	plasminogen activator, urokinase receptor	0.553
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.520
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.507
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.434	Rat
PLAU	plasminogen activator, urokinase	0.411	Rat
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.321
AXL	AXL receptor tyrosine kinase	0.304
FYN	FYN oncogene related to SRC, FGR, YES	0.297
ENG	endoglin	0.279
SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	0.262	Rat
SMAD3	SMAD family member 3	0.262
FN1	fibronectin 1	0.247	Rat
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.211
HLA-DMB	major histocompatibility complex, class II, DM beta	0.210
IL1B	interleukin 1, beta	0.209	Rat
PDX1	pancreatic and duodenal homeobox 1	0.187	Mouse
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.182
BBS1	Bardet-Biedl syndrome 1	0.174
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.172
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.163
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.154	Rat
VIM	vimentin	0.152
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.142
CCNY	cyclin Y	0.142
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.109
HNF4A	hepatocyte nuclear factor 4, alpha	0.104	Mouse Rat
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.101	Human
NCF1	neutrophil cytosolic factor 1	0.086
NOSTRIN	nitric oxide synthase trafficker	0.083
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.078
IL8	interleukin 8	0.076
SPTBN4	spectrin, beta, non-erythrocytic 4	0.071
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.070
HIPK2	homeodomain interacting protein kinase 2	0.065
NEUROD1	neurogenic differentiation 1	0.065
SNAP25	synaptosomal-associated protein, 25kDa	0.061
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.060
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.060
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.060
PRDX1	peroxiredoxin 1	0.057
SOD2	superoxide dismutase 2, mitochondrial	0.056
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.056
IER3	immediate early response 3	0.056
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.053
IL1R1	interleukin 1 receptor, type I	0.052	Rat
HDAC3	histone deacetylase 3	0.051
STX5	syntaxin 5	0.049
ONECUT1	one cut homeobox 1	0.048
S100B	S100 calcium binding protein B	0.047
MPDZ	multiple PDZ domain protein	0.047
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.047
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.046
SREBF2	sterol regulatory element binding transcription factor 2	0.046
SNAI1	snail homolog 1 (Drosophila)	0.046
CRHR1	corticotropin releasing hormone receptor 1	0.045
IL1RAP	interleukin 1 receptor accessory protein	0.044
FADD	Fas (TNFRSF6)-associated via death domain	0.043
SNAP23	synaptosomal-associated protein, 23kDa	0.043
MAPT	microtubule-associated protein tau	0.041
HDAC1	histone deacetylase 1	0.039
BCL3	B-cell CLL/lymphoma 3	0.038
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.037
MKL1	megakaryoblastic leukemia (translocation) 1	0.037
HNF1B	HNF1 homeobox B	0.037	Mouse
BHLHE40	basic helix-loop-helix family, member e40	0.035
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.035	Rat
VEGFA	vascular endothelial growth factor A	0.034
CYR61	cysteine-rich, angiogenic inducer, 61	0.033
EGR3	early growth response 3	0.033
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.033
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.033
ESR1	estrogen receptor 1	0.033
HNF1A	HNF1 homeobox A	0.033	Mouse
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.032
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.031	Human
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.031
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.031
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.031
CREBBP	CREB binding protein	0.030
ARRB2	arrestin, beta 2	0.030
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.030
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.030
AMBP	alpha-1-microglobulin/bikunin precursor	0.030
SPRR2A	small proline-rich protein 2A	0.029
EP300	E1A binding protein p300	0.029
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.029
INCENP	inner centromere protein antigens 135/155kDa	0.029
IL1RN	interleukin 1 receptor antagonist	0.028
MUC1	mucin 1, cell surface associated	0.028
AGXT2	alanine--glyoxylate aminotransferase 2	0.028
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.027
NCF4	neutrophil cytosolic factor 4, 40kDa	0.027
SETD8	SET domain containing (lysine methyltransferase) 8	0.027
IRS1	insulin receptor substrate 1	0.026
CD44	CD44 molecule (Indian blood group)	0.025
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.025
CDCP1	CUB domain containing protein 1	0.025
GADD45B	growth arrest and DNA-damage-inducible, beta	0.025
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.025
IQGAP1	IQ motif containing GTPase activating protein 1	0.024
BTBD2	BTB (POZ) domain containing 2	0.024
RNASE4	ribonuclease, RNase A family, 4	0.023
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.023
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.023
GRB10	growth factor receptor-bound protein 10	0.022
APAF1	apoptotic peptidase activating factor 1	0.022
MYOD1	myogenic differentiation 1	0.022
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.022
TGFB3	transforming growth factor, beta 3	0.022
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.022
PROX1	prospero homeobox 1	0.021
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.021
RYR2	ryanodine receptor 2 (cardiac)	0.020
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.020
SOCS1	suppressor of cytokine signaling 1	0.020
GATA2	GATA binding protein 2	0.020
COASY	CoA synthase	0.019
CDX2	caudal type homeobox 2	0.018
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.018
MED15	mediator complex subunit 15	0.018
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.018
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.018
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.018
AEBP1	AE binding protein 1	0.018
KLF6	Kruppel-like factor 6	0.018
CCND3	cyclin D3	0.018
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.017
TBX5	T-box 5	0.017
PIM1	pim-1 oncogene	0.017
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.017
DERL1	Der1-like domain family, member 1	0.017
IRF2	interferon regulatory factor 2	0.017
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.017
PLAT	plasminogen activator, tissue	0.017
PXN	paxillin	0.016
ULK1	unc-51-like kinase 1 (C. elegans)	0.016
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.016
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.016	Rat
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.016
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.016	Human
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.016
TCF12	transcription factor 12	0.016
SPHK1	sphingosine kinase 1	0.016
RGS2	regulator of G-protein signaling 2, 24kDa	0.016
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.016	Rat
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.016
AR	androgen receptor	0.015
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.015
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.015
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.015
CCL2	chemokine (C-C motif) ligand 2	0.015
ATN1	atrophin 1	0.015
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.015
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.014
EMP1	epithelial membrane protein 1	0.014
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.014
GAS2L3	growth arrest-specific 2 like 3	0.014
APOA1	apolipoprotein A-I	0.014
SETD7	SET domain containing (lysine methyltransferase) 7	0.014
SRCIN1	SRC kinase signaling inhibitor 1	0.014
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.014
NME3	non-metastatic cells 3, protein expressed in	0.014
CAV1	caveolin 1, caveolae protein, 22kDa	0.014
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.014
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.013
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.013
TRIB1	tribbles homolog 1 (Drosophila)	0.013
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.013
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.013
HMGA1	high mobility group AT-hook 1	0.013
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.013
FEV	FEV (ETS oncogene family)	0.013
PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	0.013
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.013	Rat
FSTL1	follistatin-like 1	0.013
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.013
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.013
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.012
SLC38A2	solute carrier family 38, member 2	0.012
AKAP11	A kinase (PRKA) anchor protein 11	0.012
RIPK2	receptor-interacting serine-threonine kinase 2	0.012
POU4F2	POU class 4 homeobox 2	0.012
DAXX	death-domain associated protein	0.012
NCOR2	nuclear receptor corepressor 2	0.012
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.012
BCAR1	breast cancer anti-estrogen resistance 1	0.012
MSN	moesin	0.012
COL18A1	collagen, type XVIII, alpha 1	0.012
XIAP	X-linked inhibitor of apoptosis	0.012
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.012
RIF1	RAP1 interacting factor homolog (yeast)	0.012
GJA1	gap junction protein, alpha 1, 43kDa	0.012
HMG20B	high mobility group 20B	0.012
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.012
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.012
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.012
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.011
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.011
C16orf75	chromosome 16 open reading frame 75	0.011
PCOLCE	procollagen C-endopeptidase enhancer	0.011
ALB	albumin	0.011
TGFBR1	transforming growth factor, beta receptor 1	0.011
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.011
PSEN2	presenilin 2 (Alzheimer disease 4)	0.011
ADM	adrenomedullin	0.011
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.011
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.011
NME4	non-metastatic cells 4, protein expressed in	0.011
SFTPC	surfactant protein C	0.011
FKBP8	FK506 binding protein 8, 38kDa	0.011
ARRDC3	arrestin domain containing 3	0.011
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.011	Rat
MYO16	myosin XVI	0.011
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.011
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.011
BAI1	brain-specific angiogenesis inhibitor 1	0.011
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.011
YY1	YY1 transcription factor	0.011
BCKDK	branched chain ketoacid dehydrogenase kinase	0.011
PRKCA	protein kinase C, alpha	0.011
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.011
F2	coagulation factor II (thrombin)	0.011
NKX6-1	NK6 homeobox 1	0.011
HCFC1	host cell factor C1 (VP16-accessory protein)	0.011
ND5	NADH dehydrogenase, subunit 5 (complex I)	0.011
CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.011
MT1A	metallothionein 1A	0.010
SP1	Sp1 transcription factor	0.010
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.010
MAPK8	mitogen-activated protein kinase 8	0.010
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.010
MYT1	myelin transcription factor 1	0.010
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.010
COL6A1	collagen, type VI, alpha 1	0.010
RUNX1	runt-related transcription factor 1	0.010