IMP

Process View

Homo sapiens

19 genes annotated in human

mitotic cytokinesis

A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitotic cytokinesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitotic cytokinesis" (in gray)

Name	Description	Probability	Func Analog Organism
RHOA	ras homolog gene family, member A	0.979	Fly
CDK1	cyclin-dependent kinase 1	0.897
ACTB	actin, beta	0.851
SNX9	sorting nexin 9	0.739
ARHGAP1	Rho GTPase activating protein 1	0.629
MYH9	myosin, heavy chain 9, non-muscle	0.594	Human Worm Fly
ANKRD28	ankyrin repeat domain 28	0.547
TSG101	tumor susceptibility gene 101	0.472
AURKB	aurora kinase B	0.461	Fly
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.440
ADAM15	ADAM metallopeptidase domain 15	0.394
PLK1	polo-like kinase 1	0.390
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.321
CCNB1	cyclin B1	0.304	Fly
RACGAP1	Rac GTPase activating protein 1	0.297
CENPA	centromere protein A	0.229
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.227
INCENP	inner centromere protein antigens 135/155kDa	0.207
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.197
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.190
FASLG	Fas ligand (TNF superfamily, member 6)	0.175
PTTG1	pituitary tumor-transforming 1	0.168
CCNA2	cyclin A2	0.167
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.158
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.152
TUBB	tubulin, beta	0.149
SKA1	spindle and kinetochore associated complex subunit 1	0.140
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.134
SNX33	sorting nexin 33	0.132
DNM1	dynamin 1	0.130	Fly
WASL	Wiskott-Aldrich syndrome-like	0.130
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.118
ANLN	anillin, actin binding protein	0.117
SEPT2	septin 2	0.116	Yeast
SFN	stratifin	0.115
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.111
SNAP25	synaptosomal-associated protein, 25kDa	0.109	Zebrafish
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.107
MKI67	antigen identified by monoclonal antibody Ki-67	0.107
ITSN1	intersectin 1 (SH3 domain protein)	0.102
DCK	deoxycytidine kinase	0.099
SGOL1	shugoshin-like 1 (S. pombe)	0.098
KIF4A	kinesin family member 4A	0.092
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.090
BIRC5	baculoviral IAP repeat containing 5	0.089
CDCA2	cell division cycle associated 2	0.088
SKA2	spindle and kinetochore associated complex subunit 2	0.087
SPAG5	sperm associated antigen 5	0.086
GAS2L3	growth arrest-specific 2 like 3	0.085
STX1A	syntaxin 1A (brain)	0.085	Fly
CDK2	cyclin-dependent kinase 2	0.081
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.074
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.074
UBC	ubiquitin C	0.073
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.073
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.065
EHD1	EH-domain containing 1	0.065
SEPT7	septin 7	0.064	Yeast Fly
TACC3	transforming, acidic coiled-coil containing protein 3	0.063
YY1	YY1 transcription factor	0.061
EXOC4	exocyst complex component 4	0.061
SKA3	spindle and kinetochore associated complex subunit 3	0.060
ACTA2	actin, alpha 2, smooth muscle, aorta	0.057
FOXM1	forkhead box M1	0.057
TUBA1C	tubulin, alpha 1c	0.055
CP110	CP110 protein	0.053
TUBA1B	tubulin, alpha 1b	0.052
KIF23	kinesin family member 23	0.052	Zebrafish Fly
CDCA8	cell division cycle associated 8	0.050	Fly
RBBP4	retinoblastoma binding protein 4	0.050	Fly
CDKN3	cyclin-dependent kinase inhibitor 3	0.047
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.047
MPRIP	myosin phosphatase Rho interacting protein	0.047
PTPRN	protein tyrosine phosphatase, receptor type, N	0.047
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.045
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.043	Worm Fly
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.043
KIF1B	kinesin family member 1B	0.043
PCM1	pericentriolar material 1	0.043
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.042
RBBP7	retinoblastoma binding protein 7	0.041	Fly
KIF20A	kinesin family member 20A	0.041
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.038
CENPE	centromere protein E, 312kDa	0.038
TP53	tumor protein p53	0.037
HJURP	Holliday junction recognition protein	0.037
ANAPC5	anaphase promoting complex subunit 5	0.036
KDM1A	lysine (K)-specific demethylase 1A	0.036
GTSE1	G-2 and S-phase expressed 1	0.036
CKAP2L	cytoskeleton associated protein 2-like	0.035	Human
HTT	huntingtin	0.034
TTK	TTK protein kinase	0.034
KIF2C	kinesin family member 2C	0.033
RFWD2	ring finger and WD repeat domain 2	0.032
ZRANB1	zinc finger, RAN-binding domain containing 1	0.032
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.032
ECT2	epithelial cell transforming sequence 2 oncogene	0.031	Worm Fly
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.030
CKS2	CDC28 protein kinase regulatory subunit 2	0.030
CUL7	cullin 7	0.030
CUL9	cullin 9	0.030	Human
ANAPC4	anaphase promoting complex subunit 4	0.030
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.029
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.029
DEPDC1B	DEP domain containing 1B	0.028
ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.028
NCAPG2	non-SMC condensin II complex, subunit G2	0.028
MYL12B	myosin, light chain 12B, regulatory	0.028	Worm Fly
CCNE1	cyclin E1	0.028
CCNB2	cyclin B2	0.028	Fly
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.028
DMAP1	DNA methyltransferase 1 associated protein 1	0.027
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.027
TUBB3	tubulin, beta 3	0.027
TUBGCP3	tubulin, gamma complex associated protein 3	0.027
SEC31A	SEC31 homolog A (S. cerevisiae)	0.026
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.025
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.024
RBL1	retinoblastoma-like 1 (p107)	0.024
AURKA	aurora kinase A	0.023
CDCA3	cell division cycle associated 3	0.023
TOP2B	topoisomerase (DNA) II beta 180kDa	0.022
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.022
DHCR7	7-dehydrocholesterol reductase	0.022
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.022
CDCA5	cell division cycle associated 5	0.022
C20orf20	chromosome 20 open reading frame 20	0.021
ZNF512B	zinc finger protein 512B	0.021
PRKCI	protein kinase C, iota	0.021
TK1	thymidine kinase 1, soluble	0.020
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.020
DNM2	dynamin 2	0.020	Fly
EXOC7	exocyst complex component 7	0.020
USP45	ubiquitin specific peptidase 45	0.020
FAM64A	family with sequence similarity 64, member A	0.019
CHMP1B	chromatin modifying protein 1B	0.019
KIF11	kinesin family member 11	0.019
INO80	INO80 homolog (S. cerevisiae)	0.019
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.019
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.019
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.018
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.018
SEPT11	septin 11	0.018
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.018
APLP1	amyloid beta (A4) precursor-like protein 1	0.018
SEPT1	septin 1	0.017	Yeast
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.016	Yeast
ACACA	acetyl-CoA carboxylase alpha	0.016
TUBA1A	tubulin, alpha 1a	0.016
GPSM2	G-protein signaling modulator 2	0.016
STAMBP	STAM binding protein	0.016
SYT1	synaptotagmin I	0.016
IQGAP1	IQ motif containing GTPase activating protein 1	0.016
PDCD6IP	programmed cell death 6 interacting protein	0.016
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.016
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.016
FADS1	fatty acid desaturase 1	0.015
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.015
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.015
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.015
DEPDC1	DEP domain containing 1	0.015
ACTG1	actin, gamma 1	0.015
NUSAP1	nucleolar and spindle associated protein 1	0.015
BBS2	Bardet-Biedl syndrome 2	0.014
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.014
AMPH	amphiphysin	0.014
BIRC6	baculoviral IAP repeat containing 6	0.014
CRIP2	cysteine-rich protein 2	0.014
KIF5B	kinesin family member 5B	0.014
MED12	mediator complex subunit 12	0.014
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.014
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.014
POC1A	POC1 centriolar protein homolog A (Chlamydomonas)	0.014
PRNP	prion protein	0.013
TMSB4X	thymosin beta 4, X-linked	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
TRPM7	transient receptor potential cation channel, subfamily M, member 7	0.013
PBX1	pre-B-cell leukemia homeobox 1	0.013
RRM2	ribonucleotide reductase M2	0.013
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.013
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.013
SMAD2	SMAD family member 2	0.013
KIF18A	kinesin family member 18A	0.013
NEURL4	neuralized homolog 4 (Drosophila)	0.013
HUWE1	HECT, UBA and WWE domain containing 1	0.013
GFI1B	growth factor independent 1B transcription repressor	0.013
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.013
MELK	maternal embryonic leucine zipper kinase	0.013
KIF20B	kinesin family member 20B	0.013
SEPT6	septin 6	0.012	Fly
ANAPC7	anaphase promoting complex subunit 7	0.012
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.012	Worm
FLNA	filamin A, alpha	0.012
SERTAD4	SERTA domain containing 4	0.012
TRIM59	tripartite motif containing 59	0.012
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.012
PLRG1	pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)	0.012
DIAPH3	diaphanous homolog 3 (Drosophila)	0.012	Fly
HDAC1	histone deacetylase 1	0.012
FNBP1	formin binding protein 1	0.012
TUBB2C	tubulin, beta 2C	0.012
PRRT2	proline-rich transmembrane protein 2	0.012
CAPZA1	capping protein (actin filament) muscle Z-line, alpha 1	0.012
TNIK	TRAF2 and NCK interacting kinase	0.012
SPTBN1	spectrin, beta, non-erythrocytic 1	0.012
TFDP1	transcription factor Dp-1	0.012
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.012
CUL2	cullin 2	0.011
PRC1	protein regulator of cytokinesis 1	0.011	Fly
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.011
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.011
NCAPD2	non-SMC condensin I complex, subunit D2	0.011
UBE2C	ubiquitin-conjugating enzyme E2C	0.011
DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	0.011
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.011
ANAPC11	anaphase promoting complex subunit 11	0.011
NCOR1	nuclear receptor corepressor 1	0.011
PSRC1	proline/serine-rich coiled-coil 1	0.011
TPM1	tropomyosin 1 (alpha)	0.011
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.011
SHCBP1	SHC SH2-domain binding protein 1	0.011
FAM83D	family with sequence similarity 83, member D	0.011
DEK	DEK oncogene	0.011
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.011
CHUK	conserved helix-loop-helix ubiquitous kinase	0.011
SEPT9	septin 9	0.011
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.010
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.010
MAGOHB	mago-nashi homolog B (Drosophila)	0.010
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.010
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.010