IMP
Process View
negative regulation of peptidyl tyrosine phosphorylation
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of peptidyl tyrosine phosphorylation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 1.000 | Human | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 1.000 | Human | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 1.000 | Human Fly | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.999 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.999 | Fly | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.998 | Human | |
| EGFR | epidermal growth factor receptor | 0.986 | ||
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.983 | Human | |
| GHR | growth hormone receptor | 0.933 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.922 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.900 | Human | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.889 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.860 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.819 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.730 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.708 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.582 | ||
| SYK | spleen tyrosine kinase | 0.557 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.541 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.499 | ||
| SFN | stratifin | 0.434 | ||
| NCK1 | NCK adaptor protein 1 | 0.421 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.387 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.350 | ||
| PRKCZ | protein kinase C, zeta | 0.308 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.300 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.277 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.267 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.257 | ||
| SH2D1A | SH2 domain containing 1A | 0.236 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.217 | ||
| SPRR2A | small proline-rich protein 2A | 0.215 | ||
| MUC1 | mucin 1, cell surface associated | 0.209 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.208 | ||
| PSEN1 | presenilin 1 | 0.202 | Mouse | |
| EZR | ezrin | 0.202 | Human | |
| ZNF496 | zinc finger protein 496 | 0.192 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.188 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.173 | Human Mouse | |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.162 | ||
| BLNK | B-cell linker | 0.160 | ||
| PRKCB | protein kinase C, beta | 0.154 | ||
| CD44 | CD44 molecule (Indian blood group) | 0.152 | ||
| NOXA1 | NADPH oxidase activator 1 | 0.151 | ||
| ITK | IL2-inducible T-cell kinase | 0.147 | ||
| IRS1 | insulin receptor substrate 1 | 0.144 | ||
| EPOR | erythropoietin receptor | 0.141 | ||
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.140 | ||
| LAT | linker for activation of T cells | 0.137 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.137 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.130 | ||
| TFF1 | trefoil factor 1 | 0.128 | ||
| SH2D3A | SH2 domain containing 3A | 0.117 | ||
| JAK2 | Janus kinase 2 | 0.115 | ||
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.115 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.096 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.092 | Human | |
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.086 | ||
| PROX1 | prospero homeobox 1 | 0.080 | ||
| SCHIP1 | schwannomin interacting protein 1 | 0.078 | ||
| MED28 | mediator complex subunit 28 | 0.078 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.078 | Human | |
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.074 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.070 | ||
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.069 | ||
| PTEN | phosphatase and tensin homolog | 0.066 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.064 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.063 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.062 | Mouse | |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.060 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.059 | ||
| CUL2 | cullin 2 | 0.059 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.058 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.057 | ||
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.055 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.053 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.053 | ||
| FLNA | filamin A, alpha | 0.051 | ||
| CD84 | CD84 molecule | 0.046 | ||
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.045 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.042 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.042 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.041 | ||
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.039 | ||
| TNS4 | tensin 4 | 0.037 | ||
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.037 | ||
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.037 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.037 | ||
| NCSTN | nicastrin | 0.036 | ||
| NRG1 | neuregulin 1 | 0.036 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.036 | ||
| PRKCA | protein kinase C, alpha | 0.035 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.035 | ||
| CD2AP | CD2-associated protein | 0.035 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.033 | ||
| CDCP1 | CUB domain containing protein 1 | 0.033 | ||
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.032 | ||
| FLNB | filamin B, beta | 0.032 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.031 | ||
| CAV2 | caveolin 2 | 0.030 | ||
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.030 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.029 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.028 | ||
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.027 | ||
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.027 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.026 | Mouse | |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.026 | ||
| SH2D2A | SH2 domain containing 2A | 0.026 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.025 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.024 | ||
| SLA | Src-like-adaptor | 0.024 | ||
| JAK3 | Janus kinase 3 | 0.024 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.024 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.024 | ||
| CD247 | CD247 molecule | 0.023 | ||
| CSK | c-src tyrosine kinase | 0.023 | ||
| APH1A | anterior pharynx defective 1 homolog A (C. elegans) | 0.022 | ||
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.021 | ||
| MAPT | microtubule-associated protein tau | 0.020 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.020 | ||
| APP | amyloid beta (A4) precursor protein | 0.020 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.020 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.019 | ||
| HCK | hemopoietic cell kinase | 0.019 | Human | |
| CD28 | CD28 molecule | 0.019 | ||
| PICK1 | protein interacting with PRKCA 1 | 0.018 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.018 | ||
| ESR1 | estrogen receptor 1 | 0.018 | ||
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.018 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.018 | ||
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.018 | ||
| RPL10 | ribosomal protein L10 | 0.017 | ||
| TNS3 | tensin 3 | 0.017 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.017 | ||
| NF2 | neurofibromin 2 (merlin) | 0.017 | ||
| NACAD | NAC alpha domain containing | 0.017 | ||
| CD22 | CD22 molecule | 0.016 | ||
| NTF3 | neurotrophin 3 | 0.016 | ||
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.016 | ||
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.015 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.015 | ||
| TRIM9 | tripartite motif containing 9 | 0.015 | ||
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.014 | ||
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.014 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.014 | ||
| CD33 | CD33 molecule | 0.014 | ||
| SORBS2 | sorbin and SH3 domain containing 2 | 0.014 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.014 | ||
| BLK | B lymphoid tyrosine kinase | 0.014 | Human | |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.014 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.014 | ||
| PRKCQ | protein kinase C, theta | 0.014 | Human | |
| CRY1 | cryptochrome 1 (photolyase-like) | 0.014 | ||
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.014 | ||
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.014 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.014 | ||
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.014 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.013 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.013 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.013 | ||
| EGF | epidermal growth factor | 0.013 | ||
| FES | feline sarcoma oncogene | 0.013 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.013 | ||
| NUMB | numb homolog (Drosophila) | 0.013 | ||
| DOK4 | docking protein 4 | 0.013 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.013 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.013 | ||
| BDNF | brain-derived neurotrophic factor | 0.012 | Human | |
| CISH | cytokine inducible SH2-containing protein | 0.012 | Human | |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.012 | Mouse | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.012 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.012 | ||
| DLG5 | discs, large homolog 5 (Drosophila) | 0.012 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.012 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.012 | ||
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.011 | Human | |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.011 | ||
| CTTN | cortactin | 0.011 | ||
| BAD | BCL2-associated agonist of cell death | 0.011 | ||
| MAP1S | microtubule-associated protein 1S | 0.011 | ||
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.011 | ||
| NSF | N-ethylmaleimide-sensitive factor | 0.011 | ||
| PXN | paxillin | 0.011 | ||
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.011 | ||
| GRAP2 | GRB2-related adaptor protein 2 | 0.011 | Fly | |
| DLG4 | discs, large homolog 4 (Drosophila) | 0.011 | ||
| RIN1 | Ras and Rab interactor 1 | 0.011 | ||
| CYTB | cytochrome b | 0.010 | ||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.010 | ||
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.010 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.010 | ||
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.010 |