IMP

Process View

Mus musculus

12 genes annotated in mouse

cardiac myofibril assembly

The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cardiac myofibril assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cardiac myofibril assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.997
Hand2	heart and neural crest derivatives expressed transcript 2	0.997
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.994
Shh	sonic hedgehog	0.959
Vegfa	vascular endothelial growth factor A	0.955
Sox9	SRY-box containing gene 9	0.918
Hand1	heart and neural crest derivatives expressed transcript 1	0.905
Myl3	myosin, light polypeptide 3	0.899	Zebrafish
Actc1	actin, alpha, cardiac muscle 1	0.893
Myl9	myosin, light polypeptide 9, regulatory	0.881	Mouse
Foxc2	forkhead box C2	0.860
Nos3	nitric oxide synthase 3, endothelial cell	0.844
Tagln	transgelin	0.841
Kdr	kinase insert domain protein receptor	0.827	Mouse
Tgfb2	transforming growth factor, beta 2	0.824
Actn2	actinin alpha 2	0.794
Fgf8	fibroblast growth factor 8	0.765
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.736
Gata4	GATA binding protein 4	0.689
Fgfr2	fibroblast growth factor receptor 2	0.664
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.624
Ldb3	LIM domain binding 3	0.599
Cnn2	calponin 2	0.580
Bmp4	bone morphogenetic protein 4	0.570
Csf1	colony stimulating factor 1 (macrophage)	0.548
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.537
Pitx2	paired-like homeodomain transcription factor 2	0.536
Foxc1	forkhead box C1	0.484
Msx1	homeobox, msh-like 1	0.477
Prrx1	paired related homeobox 1	0.461
Tbx5	T-box 5	0.423
Cnn1	calponin 1	0.419
Mef2c	myocyte enhancer factor 2C	0.367	Mouse
Actg2	actin, gamma 2, smooth muscle, enteric	0.345	Mouse
Tnnc1	troponin C, cardiac/slow skeletal	0.336
Hrc	histidine rich calcium binding protein	0.328
Gata6	GATA binding protein 6	0.319
Meox2	mesenchyme homeobox 2	0.313
Pfn1	profilin 1	0.293
Acvr1	activin A receptor, type 1	0.280
Mesp1	mesoderm posterior 1	0.275
Tbx1	T-box 1	0.262
Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	0.251
Isl1	ISL1 transcription factor, LIM/homeodomain	0.247
Gja1	gap junction protein, alpha 1	0.245
Mybpc3	myosin binding protein C, cardiac	0.203
Ntf3	neurotrophin 3	0.202
Gli2	GLI-Kruppel family member GLI2	0.182
Tbx3	T-box 3	0.182
Pax3	paired box gene 3	0.177
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.172
Casq2	calsequestrin 2	0.170
Csrp3	cysteine and glycine-rich protein 3	0.165
Art1	ADP-ribosyltransferase 1	0.165
Gsc	goosecoid homeobox	0.161
Alx4	aristaless-like homeobox 4	0.160
Tgfbr2	transforming growth factor, beta receptor II	0.152
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.151
Actg1	actin, gamma, cytoplasmic 1	0.148	Mouse
Actb	actin, beta	0.144	Mouse
Hdac4	histone deacetylase 4	0.140
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.140	Mouse
Tnnt3	troponin T3, skeletal, fast	0.134
Scn5a	sodium channel, voltage-gated, type V, alpha	0.134
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.133
Des	desmin	0.130
Ednra	endothelin receptor type A	0.122
Col1a1	collagen, type I, alpha 1	0.119
Nkx6-1	NK6 homeobox 1	0.119
Tnni2	troponin I, skeletal, fast 2	0.118
Lmna	lamin A	0.115
Cdh5	cadherin 5	0.114
Tgfb1	transforming growth factor, beta 1	0.111
Runx2	runt related transcription factor 2	0.108
Nrp1	neuropilin 1	0.108
Tnnc2	troponin C2, fast	0.108
Nrap	nebulin-related anchoring protein	0.106	Mouse
Wdr1	WD repeat domain 1	0.104
Kitl	kit ligand	0.102
Xirp1	xin actin-binding repeat containing 1	0.098
Acta2	actin, alpha 2, smooth muscle, aorta	0.096	Mouse
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.095
Cxadr	coxsackie virus and adenovirus receptor	0.095
Bmp2	bone morphogenetic protein 2	0.093
Zeb1	zinc finger E-box binding homeobox 1	0.091
Prkce	protein kinase C, epsilon	0.089
Rxra	retinoid X receptor alpha	0.089
Efnb2	ephrin B2	0.088
Ryr2	ryanodine receptor 2, cardiac	0.087
Hdac5	histone deacetylase 5	0.083
Nf1	neurofibromatosis 1	0.083
Nppa	natriuretic peptide type A	0.082
Tmsb4x	thymosin, beta 4, X chromosome	0.081
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.081
Kcnk3	potassium channel, subfamily K, member 3	0.080
Tpm2	tropomyosin 2, beta	0.076
Ckm	creatine kinase, muscle	0.072
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.072
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.072
Tpm1	tropomyosin 1, alpha	0.069
Ckmt2	creatine kinase, mitochondrial 2	0.068
Tcf15	transcription factor 15	0.067
Bmp7	bone morphogenetic protein 7	0.067
Pdx1	pancreatic and duodenal homeobox 1	0.066
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.065
Flna	filamin, alpha	0.065
Ttn	titin	0.064
Srebf2	sterol regulatory element binding factor 2	0.063
Ilk	integrin linked kinase	0.062
Acta1	actin, alpha 1, skeletal muscle	0.062	Mouse
Flt4	FMS-like tyrosine kinase 4	0.060	Mouse
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.059
Gja5	gap junction protein, alpha 5	0.058
Ptch1	patched homolog 1	0.058
Cbl	Casitas B-lineage lymphoma	0.053
Zfpm2	zinc finger protein, multitype 2	0.052
Tcfap2a	transcription factor AP-2, alpha	0.052
Pgam2	phosphoglycerate mutase 2	0.051
Plxnd1	plexin D1	0.051
Pitx1	paired-like homeodomain transcription factor 1	0.050
Smtn	smoothelin	0.049
Actn1	actinin, alpha 1	0.048
Flnc	filamin C, gamma	0.048
Tnnt2	troponin T2, cardiac	0.048
Rarb	retinoic acid receptor, beta	0.048
Casq1	calsequestrin 1	0.048
Capzb	capping protein (actin filament) muscle Z-line, beta	0.047
Ighmbp2	immunoglobulin mu binding protein 2	0.047
Eya1	eyes absent 1 homolog (Drosophila)	0.046
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.046
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.046
Hoxd13	homeobox D13	0.046
Myom1	myomesin 1	0.045
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.045
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.045	Mouse
Gata5	GATA binding protein 5	0.045
Hspb2	heat shock protein 2	0.044
Ctnnb1	catenin (cadherin associated protein), beta 1	0.044
Myo1c	myosin IC	0.044
Otp	orthopedia homolog (Drosophila)	0.043
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.043
Myh9	myosin, heavy polypeptide 9, non-muscle	0.042	Mouse
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.042
Tcap	titin-cap	0.042	Human
Cotl1	coactosin-like 1 (Dictyostelium)	0.041
Lmx1b	LIM homeobox transcription factor 1 beta	0.040
Jup	junction plakoglobin	0.039
Fbn2	fibrillin 2	0.039
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.039
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.038
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.037
Cfl1	cofilin 1, non-muscle	0.037
Foxa2	forkhead box A2	0.037
Ank1	ankyrin 1, erythroid	0.037
Vegfc	vascular endothelial growth factor C	0.036
Popdc3	popeye domain containing 3	0.036
Vcl	vinculin	0.036
Srpk3	serine/arginine-rich protein specific kinase 3	0.035
Pdlim3	PDZ and LIM domain 3	0.035
Art5	ADP-ribosyltransferase 5	0.035
Ptprb	protein tyrosine phosphatase, receptor type, B	0.035
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.035
Tln1	talin 1	0.034
Tnnt1	troponin T1, skeletal, slow	0.034
Ikzf1	IKAROS family zinc finger 1	0.034
Mrvi1	MRV integration site 1	0.033
Ednrb	endothelin receptor type B	0.033
Myl1	myosin, light polypeptide 1	0.033
Pthlh	parathyroid hormone-like peptide	0.033
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.033
Smo	smoothened homolog (Drosophila)	0.031
U46068	cDNA sequence U46068	0.031
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.031
Kbtbd5	kelch repeat and BTB (POZ) domain containing 5	0.031
Ece1	endothelin converting enzyme 1	0.031
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.030
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.030
Foxe1	forkhead box E1	0.029
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.029
Popdc2	popeye domain containing 2	0.028
Tnni1	troponin I, skeletal, slow 1	0.028
Btbd17	BTB (POZ) domain containing 17	0.028
Plcg1	phospholipase C, gamma 1	0.027
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.027
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.027
Sox4	SRY-box containing gene 4	0.027
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.026
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.025
Myom2	myomesin 2	0.025
Myocd	myocardin	0.025
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.024
Iqcb1	IQ calmodulin-binding motif containing 1	0.024
Hoxa13	homeobox A13	0.024
Jag1	jagged 1	0.024
C1qb	complement component 1, q subcomponent, beta polypeptide	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.023
Smyd1	SET and MYND domain containing 1	0.023
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.023
Myl7	myosin, light polypeptide 7, regulatory	0.022	Zebrafish Mouse
Mylk	myosin, light polypeptide kinase	0.022
Plec	plectin	0.022
Myh10	myosin, heavy polypeptide 10, non-muscle	0.022
Hlx	H2.0-like homeobox	0.022
Dlx2	distal-less homeobox 2	0.022
Trim54	tripartite motif-containing 54	0.022
Ebf2	early B-cell factor 2	0.022
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.022
Gli3	GLI-Kruppel family member GLI3	0.021
Actn3	actinin alpha 3	0.021
Msx2	homeobox, msh-like 2	0.021
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.021
Tuba1a	tubulin, alpha 1A	0.021
Fgfr3	fibroblast growth factor receptor 3	0.020
Vax1	ventral anterior homeobox containing gene 1	0.020
Mn1	meningioma 1	0.020
She	src homology 2 domain-containing transforming protein E	0.020
Fgf17	fibroblast growth factor 17	0.020
Epor	erythropoietin receptor	0.020
Mef2d	myocyte enhancer factor 2D	0.020	Mouse
Mitf	microphthalmia-associated transcription factor	0.020
Rpgrip1l	Rpgrip1-like	0.020
Fgfr1	fibroblast growth factor receptor 1	0.020
Alx1	ALX homeobox 1	0.019
Tuba4a	tubulin, alpha 4A	0.019
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.019
Alx3	aristaless-like homeobox 3	0.019
Fgfrl1	fibroblast growth factor receptor-like 1	0.019
Sox7	SRY-box containing gene 7	0.019
Vangl2	vang-like 2 (van gogh, Drosophila)	0.019
Notch2	Notch gene homolog 2 (Drosophila)	0.019
Kctd10	potassium channel tetramerisation domain containing 10	0.018
Tcf21	transcription factor 21	0.018
Nog	noggin	0.018
Dlx6	distal-less homeobox 6	0.018
Epas1	endothelial PAS domain protein 1	0.018
Msn	moesin	0.018
Insm1	insulinoma-associated 1	0.018
Pax9	paired box gene 9	0.018
Fitm1	fat storage-inducing transmembrane protein 1	0.018
Gab2	growth factor receptor bound protein 2-associated protein 2	0.017
Tnni3	troponin I, cardiac 3	0.017
Fyn	Fyn proto-oncogene	0.017
Csrp1	cysteine and glycine-rich protein 1	0.017	Mouse
Lmod2	leiomodin 2 (cardiac)	0.017
Gh	growth hormone	0.017
Tagln2	transgelin 2	0.017
Rxrg	retinoid X receptor gamma	0.017
Mylip	myosin regulatory light chain interacting protein	0.017
Rac1	RAS-related C3 botulinum substrate 1	0.016
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.016
Cox8b	cytochrome c oxidase, subunit VIIIb	0.016
Capn3	calpain 3	0.016
Lepr	leptin receptor	0.016
Tbx20	T-box 20	0.016
Chrm2	cholinergic receptor, muscarinic 2, cardiac	0.016
Txlnb	taxilin beta	0.016
Podxl	podocalyxin-like	0.016
Krt4	keratin 4	0.016
Hes2	hairy and enhancer of split 2 (Drosophila)	0.015
Mks1	Meckel syndrome, type 1	0.015
Rara	retinoic acid receptor, alpha	0.015
Gja3	gap junction protein, alpha 3	0.015
Pdgfb	platelet derived growth factor, B polypeptide	0.015
Icam2	intercellular adhesion molecule 2	0.015
Arpc2	actin related protein 2/3 complex, subunit 2	0.015
Heg1	HEG homolog 1 (zebrafish)	0.015
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.014
Pygm	muscle glycogen phosphorylase	0.014
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.014
Iqgap1	IQ motif containing GTPase activating protein 1	0.014
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.014
Hoxa3	homeobox A3	0.014
Tek	endothelial-specific receptor tyrosine kinase	0.014
Aplnr	apelin receptor	0.014
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.014
Barx1	BarH-like homeobox 1	0.014
Wnt11	wingless-related MMTV integration site 11	0.014
Wnk2	WNK lysine deficient protein kinase 2	0.014
Ryr1	ryanodine receptor 1, skeletal muscle	0.014
Foxg1	forkhead box G1	0.013
Emp2	epithelial membrane protein 2	0.013
Vasp	vasodilator-stimulated phosphoprotein	0.013
Pdlim7	PDZ and LIM domain 7	0.013
Hdac7	histone deacetylase 7	0.013
Xirp2	xin actin-binding repeat containing 2	0.013
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.013
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.013
Barx2	BarH-like homeobox 2	0.013
Akap6	A kinase (PRKA) anchor protein 6	0.012
Dlx5	distal-less homeobox 5	0.012
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012
Prf1	perforin 1 (pore forming protein)	0.012
Ltbp1	latent transforming growth factor beta binding protein 1	0.012
Adcy4	adenylate cyclase 4	0.012
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.011
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.011
Nkx3-2	NK3 homeobox 2	0.011	Mouse
Krt15	keratin 15	0.011
Fbxo32	F-box protein 32	0.011
Fgf10	fibroblast growth factor 10	0.011
Zeb2	zinc finger E-box binding homeobox 2	0.011
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Thbd	thrombomodulin	0.011
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.011
Zmynd11	zinc finger, MYND domain containing 11	0.011
Kbtbd10	kelch repeat and BTB (POZ) domain containing 10	0.011
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.011
Hopx	HOP homeobox	0.011
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.010
Tmem204	transmembrane protein 204	0.010
Dmpk	dystrophia myotonica-protein kinase	0.010
Mybph	myosin binding protein H	0.010
a	nonagouti	0.010
Alpk3	alpha-kinase 3	0.010
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.010	Mouse
Myadm	myeloid-associated differentiation marker	0.010
Pten	phosphatase and tensin homolog	0.010