IMP

Process View

Mus musculus

4 genes annotated in mouse

positive regulation of protein autophosphorylation

GO:0031954

Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of protein autophosphorylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of protein autophosphorylation" (in gray)

Name	Description	Probability	Func Analog Organism
Nos3	nitric oxide synthase 3, endothelial cell	0.692
Notch2	Notch gene homolog 2 (Drosophila)	0.418
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.284
Pxn	paxillin	0.279
Mdm2	transformed mouse 3T3 cell double minute 2	0.258
Prkce	protein kinase C, epsilon	0.253
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.240
Itga3	integrin alpha 3	0.236
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.223
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.212
Sept7	septin 7	0.177
Kdr	kinase insert domain protein receptor	0.175
Ece1	endothelin converting enzyme 1	0.169
Ptk2	PTK2 protein tyrosine kinase 2	0.145
Rb1	retinoblastoma 1	0.137
Igh	immunoglobulin heavy chain complex	0.135
Brca1	breast cancer 1	0.130
Chmp1b	chromatin modifying protein 1B	0.129
Tgfbr2	transforming growth factor, beta receptor II	0.129
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.125
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.096
Igfbp6	insulin-like growth factor binding protein 6	0.090
Emp2	epithelial membrane protein 2	0.090
Csf1	colony stimulating factor 1 (macrophage)	0.089
Trp53	transformation related protein 53	0.078
Ptgs2	prostaglandin-endoperoxide synthase 2	0.078
Wt1	Wilms tumor 1 homolog	0.076
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.073
Acvr1	activin A receptor, type 1	0.070
Nbn	nibrin	0.070	Human
Plxna1	plexin A1	0.070
Cav1	caveolin 1, caveolae protein	0.068
Sdcbp	syndecan binding protein	0.066
Jag1	jagged 1	0.064
Nrp1	neuropilin 1	0.059
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.058
Egln1	EGL nine homolog 1 (C. elegans)	0.057
Pax3	paired box gene 3	0.057
Plcg1	phospholipase C, gamma 1	0.057
Pdgfb	platelet derived growth factor, B polypeptide	0.056	Human
Fbln1	fibulin 1	0.053
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.053
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.049
Jak2	Janus kinase 2	0.047
Lama5	laminin, alpha 5	0.045
Rxra	retinoid X receptor alpha	0.045
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.045
Fzd4	frizzled homolog 4 (Drosophila)	0.044
Hbegf	heparin-binding EGF-like growth factor	0.043
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.043
Fgf8	fibroblast growth factor 8	0.042
Cbfb	core binding factor beta	0.041
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.041
Gata4	GATA binding protein 4	0.041
Bmp4	bone morphogenetic protein 4	0.039
Dram2	VDNA-damage regulated autophagy modulator 2	0.039
Bcar1	breast cancer anti-estrogen resistance 1	0.037
Plxnd1	plexin D1	0.036
Pdcd10	programmed cell death 10	0.036
Brca2	breast cancer 2	0.035
Phlda3	pleckstrin homology-like domain, family A, member 3	0.035
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.034
Stk17b	serine/threonine kinase 17b (apoptosis-inducing)	0.033
Trim3	tripartite motif-containing 3	0.033
Atm	ataxia telangiectasia mutated homolog (human)	0.033
Egfr	epidermal growth factor receptor	0.032
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.031
Ednra	endothelin receptor type A	0.031
Rap1b	RAS related protein 1b	0.030	Mouse
Apln	apelin	0.030
Mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.030	Human
Rbm7	RNA binding motif protein 7	0.030
Gata6	GATA binding protein 6	0.030
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.030
Rap2c	RAP2C, member of RAS oncogene family	0.030
Tspan12	tetraspanin 12	0.029
Tmed5	transmembrane emp24 protein transport domain containing 5	0.029
Fgfr1	fibroblast growth factor receptor 1	0.028
Mgp	matrix Gla protein	0.028
Ctnnbip1	catenin beta interacting protein 1	0.028
Dlg4	discs, large homolog 4 (Drosophila)	0.028
Pdgfc	platelet-derived growth factor, C polypeptide	0.028
Samd4b	sterile alpha motif domain containing 4B	0.028
Sox13	SRY-box containing gene 13	0.028
Tnks1bp1	tankyrase 1 binding protein 1	0.028
Sufu	suppressor of fused homolog (Drosophila)	0.027
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.027
Tgfb2	transforming growth factor, beta 2	0.027
Skil	SKI-like	0.027
Rab1	RAB1, member RAS oncogene family	0.026
Wwtr1	WW domain containing transcription regulator 1	0.026
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.026
Hif1a	hypoxia inducible factor 1, alpha subunit	0.026
Efnb1	ephrin B1	0.026
Pitx2	paired-like homeodomain transcription factor 2	0.026
Hoxa3	homeobox A3	0.025
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.025
Zfp651	zinc finger protein 651	0.024
Mbd2	methyl-CpG binding domain protein 2	0.024
Arpc5	actin related protein 2/3 complex, subunit 5	0.023
2810008M24Rik	RIKEN cDNA 2810008M24 gene	0.023
Crlf1	cytokine receptor-like factor 1	0.023
Gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting 3	0.023
Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2	0.023
Jup	junction plakoglobin	0.023
Chpf	chondroitin polymerizing factor	0.023
Nipsnap3b	nipsnap homolog 3B (C. elegans)	0.023
Cbs	cystathionine beta-synthase	0.023
Wnt4	wingless-related MMTV integration site 4	0.022
Shc2	SHC (Src homology 2 domain containing) transforming protein 2	0.022
Meox2	mesenchyme homeobox 2	0.022
Hiatl1	hippocampus abundant transcript-like 1	0.022
Yap1	yes-associated protein 1	0.022
Fam49b	family with sequence similarity 49, member B	0.022
Apoe	apolipoprotein E	0.021
Smtn	smoothelin	0.021
Usp25	ubiquitin specific peptidase 25	0.021
Stx7	syntaxin 7	0.021
Phldb1	pleckstrin homology-like domain, family B, member 1	0.021
Fosl2	fos-like antigen 2	0.021
Ralgds	ral guanine nucleotide dissociation stimulator	0.021
Ephb2	Eph receptor B2	0.021
Lrp1	low density lipoprotein receptor-related protein 1	0.020
Akirin1	akirin 1	0.020
Fli1	Friend leukemia integration 1	0.020
Nipa2	non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)	0.020
Nos1	nitric oxide synthase 1, neuronal	0.020
Tmem123	transmembrane protein 123	0.020
Sorbs3	sorbin and SH3 domain containing 3	0.020
Tpm4	tropomyosin 4	0.020
Mcl1	myeloid cell leukemia sequence 1	0.019
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.019
Efs	embryonal Fyn-associated substrate	0.019
Rnf115	ring finger protein 115	0.019
Acvrl1	activin A receptor, type II-like 1	0.019
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.019
Ehd4	EH-domain containing 4	0.019
Ncs1	neuronal calcium sensor 1	0.019
Nab1	Ngfi-A binding protein 1	0.018
Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	0.018
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.018
Dnm1	dynamin 1	0.018
Tspan9	tetraspanin 9	0.018
Ptp4a2	protein tyrosine phosphatase 4a2	0.018
Clip2	CAP-GLY domain containing linker protein 2	0.018
Adam17	a disintegrin and metallopeptidase domain 17	0.017
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.017
Tmem168	transmembrane protein 168	0.017
Sat1	spermidine/spermine N1-acetyl transferase 1	0.017
Krcc1	lysine-rich coiled-coil 1	0.017
Tgfbr1	transforming growth factor, beta receptor I	0.017
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.017
Npdc1	neural proliferation, differentiation and control gene 1	0.016
Foxc2	forkhead box C2	0.016
Flt4	FMS-like tyrosine kinase 4	0.016
Smad2	MAD homolog 2 (Drosophila)	0.016
Vim	vimentin	0.016
Socs5	suppressor of cytokine signaling 5	0.016
Gja1	gap junction protein, alpha 1	0.016
Lmna	lamin A	0.016
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.016
Bmp2k	BMP2 inducible kinase	0.016
Htra1	HtrA serine peptidase 1	0.016
Syap1	synapse associated protein 1	0.016
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.016
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.015
Cldn5	claudin 5	0.015
Hic1	hypermethylated in cancer 1	0.015
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.015
Ppp1r12c	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.015
Sox18	SRY-box containing gene 18	0.015
Rara	retinoic acid receptor, alpha	0.015
Tgfb1	transforming growth factor, beta 1	0.015
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.015
Gja4	gap junction protein, alpha 4	0.015
Psen1	presenilin 1	0.015
Cd44	CD44 antigen	0.015
Rtkn	rhotekin	0.015
Cabp7	calcium binding protein 7	0.015
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.015
Sh3bgrl	SH3-binding domain glutamic acid-rich protein like	0.014
App	amyloid beta (A4) precursor protein	0.014
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.014
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.014
Snx2	sorting nexin 2	0.014
Fgfr2	fibroblast growth factor receptor 2	0.014
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.014
Epas1	endothelial PAS domain protein 1	0.014
Zcchc6	zinc finger, CCHC domain containing 6	0.014
Ptgfrn	prostaglandin F2 receptor negative regulator	0.014
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.014
Sox4	SRY-box containing gene 4	0.014
Klf10	Kruppel-like factor 10	0.014
Golga7	golgi autoantigen, golgin subfamily a, 7	0.014
Abi1	abl-interactor 1	0.014
Igfbp2	insulin-like growth factor binding protein 2	0.014
Cd151	CD151 antigen	0.013
Rarg	retinoic acid receptor, gamma	0.013
Hoxa1	homeobox A1	0.013
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.013
Fyn	Fyn proto-oncogene	0.013
Mapre3	microtubule-associated protein, RP/EB family, member 3	0.013
Wnt7b	wingless-related MMTV integration site 7B	0.013
Pdgfa	platelet derived growth factor, alpha	0.013	Human
Ripply3	ripply3 homolog (zebrafish)	0.013
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.013
Yaf2	YY1 associated factor 2	0.013
Flt1	FMS-like tyrosine kinase 1	0.013
Ptrf	polymerase I and transcript release factor	0.013
Mlh1	mutL homolog 1 (E. coli)	0.013
Kifc3	kinesin family member C3	0.013
Cops2	COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)	0.013
Xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.013
Agtr1a	angiotensin II receptor, type 1a	0.013
Ren1	renin 1 structural	0.013
Mkl2	MKL/myocardin-like 2	0.013
Etfa	electron transferring flavoprotein, alpha polypeptide	0.012
Nptx1	neuronal pentraxin 1	0.012
Ddr2	discoidin domain receptor family, member 2	0.012
Dsg1a	desmoglein 1 alpha	0.012
Stxbp3a	syntaxin binding protein 3A	0.012
Nrp2	neuropilin 2	0.012
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.012
Fuz	fuzzy homolog (Drosophila)	0.012
Slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.012
Rasl10a	RAS-like, family 10, member A	0.012
Thbd	thrombomodulin	0.012
Asah1	N-acylsphingosine amidohydrolase 1	0.012
Tagln	transgelin	0.012
Ret	ret proto-oncogene	0.012
Foxn2	forkhead box N2	0.012
Snai1	snail homolog 1 (Drosophila)	0.012
Mdfic	MyoD family inhibitor domain containing	0.011
Prkci	protein kinase C, iota	0.011
Ltbp4	latent transforming growth factor beta binding protein 4	0.011
Rasip1	Ras interacting protein 1	0.011
Fstl3	follistatin-like 3	0.011
S100a16	S100 calcium binding protein A16	0.011
Tank	TRAF family member-associated Nf-kappa B activator	0.011
Emcn	endomucin	0.011
Nf1	neurofibromatosis 1	0.011
Chrd	chordin	0.011
Adra2a	adrenergic receptor, alpha 2a	0.011
Zfp277	zinc finger protein 277	0.011
Vhl	von Hippel-Lindau tumor suppressor	0.011
Arfip1	ADP-ribosylation factor interacting protein 1	0.011
Pmepa1	prostate transmembrane protein, androgen induced 1	0.011
Rap2b	RAP2B, member of RAS oncogene family	0.011
Snap23	synaptosomal-associated protein 23	0.011
Lhx6	LIM homeobox protein 6	0.011
Rheb	Ras homolog enriched in brain	0.011
Arl8a	ADP-ribosylation factor-like 8A	0.011
Timp2	tissue inhibitor of metalloproteinase 2	0.011
Pvr	poliovirus receptor	0.011
Lama4	laminin, alpha 4	0.011
Cbl	Casitas B-lineage lymphoma	0.011
Rap1a	RAS-related protein-1a	0.010	Mouse
Inhbb	inhibin beta-B	0.010
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.010
Pparg	peroxisome proliferator activated receptor gamma	0.010
Nodal	nodal	0.010
Bcl10	B-cell leukemia/lymphoma 10	0.010
Bok	BCL2-related ovarian killer protein	0.010
Cxcl14	chemokine (C-X-C motif) ligand 14	0.010
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.010
Wdr26	WD repeat domain 26	0.010
Rfwd2	ring finger and WD repeat domain 2	0.010
Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2	0.010
Sh3bp4	SH3-domain binding protein 4	0.010
Serp1	stress-associated endoplasmic reticulum protein 1	0.010
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.010
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.010
Dmd	dystrophin, muscular dystrophy	0.010
Acot9	acyl-CoA thioesterase 9	0.010