IMP

Process View

Mus musculus

9 genes annotated in mouse

endothelial cell apoptotic process

Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endothelial cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endothelial cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Mdm2	transformed mouse 3T3 cell double minute 2	0.976
Vegfa	vascular endothelial growth factor A	0.714
Vhl	von Hippel-Lindau tumor suppressor	0.690
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.628
Fgg	fibrinogen gamma chain	0.616	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.609
Fas	Fas (TNF receptor superfamily member 6)	0.505
Esam	endothelial cell-specific adhesion molecule	0.427
Cdh5	cadherin 5	0.392
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.390
Adcy4	adenylate cyclase 4	0.374
Flt4	FMS-like tyrosine kinase 4	0.306
Nf1	neurofibromatosis 1	0.297
Col4a2	collagen, type IV, alpha 2	0.268
Ptprb	protein tyrosine phosphatase, receptor type, B	0.253
Emcn	endomucin	0.249
Eng	endoglin	0.242
Kdr	kinase insert domain protein receptor	0.239	Human
Nid1	nidogen 1	0.211
Nos3	nitric oxide synthase 3, endothelial cell	0.210
Tek	endothelial-specific receptor tyrosine kinase	0.199
Col4a1	collagen, type IV, alpha 1	0.193
Sox18	SRY-box containing gene 18	0.164
Fga	fibrinogen alpha chain	0.159	Human
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.155	Mouse
Rassf1	Ras association (RalGDS/AF-6) domain family member 1	0.147
Smad3	MAD homolog 3 (Drosophila)	0.145
Apoe	apolipoprotein E	0.121
Apc	adenomatosis polyposis coli	0.109
Ccl2	chemokine (C-C motif) ligand 2	0.108
Egfr	epidermal growth factor receptor	0.107
Ambp	alpha 1 microglobulin/bikunin	0.107
Cd151	CD151 antigen	0.097
Bcl2	B-cell leukemia/lymphoma 2	0.097
Ptch1	patched homolog 1	0.096
Sox4	SRY-box containing gene 4	0.095
Wt1	Wilms tumor 1 homolog	0.093
Mt2	metallothionein 2	0.092
Eln	elastin	0.091
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.090
Mdm4	transformed mouse 3T3 cell double minute 4	0.090
Ptgs2	prostaglandin-endoperoxide synthase 2	0.089
Adm	adrenomedullin	0.089
Trp53	transformation related protein 53	0.087
Col1a2	collagen, type I, alpha 2	0.087
Gdf10	growth differentiation factor 10	0.085
Mt1	metallothionein 1	0.083
Pecam1	platelet/endothelial cell adhesion molecule 1	0.082
Cd44	CD44 antigen	0.080
Myct1	myc target 1	0.079
Shh	sonic hedgehog	0.079
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.074
Mfap2	microfibrillar-associated protein 2	0.073
Fgfr2	fibroblast growth factor receptor 2	0.072
Traf2	TNF receptor-associated factor 2	0.063
Nphs2	nephrosis 2 homolog, podocin (human)	0.062
Icam2	intercellular adhesion molecule 2	0.062
Lepr	leptin receptor	0.062
Aff1	AF4/FMR2 family, member 1	0.062
Tbx2	T-box 2	0.061
Rb1	retinoblastoma 1	0.055
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.052
Hif1a	hypoxia inducible factor 1, alpha subunit	0.049
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.046
Mcam	melanoma cell adhesion molecule	0.045
Foxf1a	forkhead box F1a	0.043
Ces1c	carboxylesterase 1C	0.043
Acvrl1	activin A receptor, type II-like 1	0.042
Grb2	growth factor receptor bound protein 2	0.042
Sdpr	serum deprivation response	0.041
Stab1	stabilin 1	0.039
She	src homology 2 domain-containing transforming protein E	0.038
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.037
Rasip1	Ras interacting protein 1	0.037
Col6a3	collagen, type VI, alpha 3	0.037
Fgb	fibrinogen beta chain	0.036	Human
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.036
Vav2	vav 2 oncogene	0.035
Col1a1	collagen, type I, alpha 1	0.035
Braf	Braf transforming gene	0.034
Col13a1	collagen, type XIII, alpha 1	0.034
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.034
Ushbp1	Usher syndrome 1C binding protein 1	0.034
Vdr	vitamin D receptor	0.033
Angptl4	angiopoietin-like 4	0.033
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.033
Il4ra	interleukin 4 receptor, alpha	0.031
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.031
Gja4	gap junction protein, alpha 4	0.031
Thbd	thrombomodulin	0.030	Mouse
Lrp2	low density lipoprotein receptor-related protein 2	0.030
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.030
Ifngr1	interferon gamma receptor 1	0.029
Hmox1	heme oxygenase (decycling) 1	0.029
Lamb2	laminin, beta 2	0.028
Cyr61	cysteine rich protein 61	0.028
Vwf	Von Willebrand factor homolog	0.028
Aqp1	aquaporin 1	0.027
Angptl3	angiopoietin-like 3	0.027	Mouse
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.027
Itga3	integrin alpha 3	0.026
Traf6	TNF receptor-associated factor 6	0.026
Mylk	myosin, light polypeptide kinase	0.026
En1	engrailed 1	0.026
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.026
Itga1	integrin alpha 1	0.025
Pten	phosphatase and tensin homolog	0.025
Pvr	poliovirus receptor	0.025
Gc	group specific component	0.025
Matn4	matrilin 4	0.025
Clec14a	C-type lectin domain family 14, member a	0.024	Mouse
Ptk2	PTK2 protein tyrosine kinase 2	0.024
Clec3b	C-type lectin domain family 3, member b	0.024
Bcl6b	B-cell CLL/lymphoma 6, member B	0.024
Selp	selectin, platelet	0.024
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.023
Tgfb1	transforming growth factor, beta 1	0.023
Bgn	biglycan	0.023
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.023
Fgfr1	fibroblast growth factor receptor 1	0.023
Mmp11	matrix metallopeptidase 11	0.022
Igfbp4	insulin-like growth factor binding protein 4	0.022
Atf3	activating transcription factor 3	0.022
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.022
Mmp9	matrix metallopeptidase 9	0.022
Nos1	nitric oxide synthase 1, neuronal	0.022
Plaur	plasminogen activator, urokinase receptor	0.021
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.021
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.021
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.021	Human
Col6a2	collagen, type VI, alpha 2	0.021
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.021
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.021
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.021
Robo4	roundabout homolog 4 (Drosophila)	0.021
Dpep1	dipeptidase 1 (renal)	0.020
Podxl	podocalyxin-like	0.020
Pparg	peroxisome proliferator activated receptor gamma	0.020
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.020
Hpx	hemopexin	0.020
Kit	kit oncogene	0.020
Dab2	disabled homolog 2 (Drosophila)	0.020
Flt1	FMS-like tyrosine kinase 1	0.019
Col6a1	collagen, type VI, alpha 1	0.019
Ctnnb1	catenin (cadherin associated protein), beta 1	0.019
Dmtf1	cyclin D binding myb-like transcription factor 1	0.019
Gpx3	glutathione peroxidase 3	0.019
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.019
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.018
Prkcd	protein kinase C, delta	0.018
Proc	protein C	0.018
Loxl1	lysyl oxidase-like 1	0.018
Egfl7	EGF-like domain 7	0.018
Notch2	Notch gene homolog 2 (Drosophila)	0.018
Epas1	endothelial PAS domain protein 1	0.018
Lama4	laminin, alpha 4	0.018
Bmp6	bone morphogenetic protein 6	0.017
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.017
Cxcl12	chemokine (C-X-C motif) ligand 12	0.017
Sox17	SRY-box containing gene 17	0.017
Col14a1	collagen, type XIV, alpha 1	0.017
Cd160	CD160 antigen	0.017
Ier3	immediate early response 3	0.017
Epha2	Eph receptor A2	0.016
Timp3	tissue inhibitor of metalloproteinase 3	0.016
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.016
Pim1	proviral integration site 1	0.016
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.016
Tnc	tenascin C	0.016
Tcf21	transcription factor 21	0.016
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.016
Gbx2	gastrulation brain homeobox 2	0.016
Pth1r	parathyroid hormone 1 receptor	0.016
C1qtnf3	C1q and tumor necrosis factor related protein 3	0.016
Tgfbr3	transforming growth factor, beta receptor III	0.016
Runx1	runt related transcription factor 1	0.015
Fgf3	fibroblast growth factor 3	0.015
Skil	SKI-like	0.015
Kng1	kininogen 1	0.015
Traf3ip2	TRAF3 interacting protein 2	0.015
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.015
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015
Trip6	thyroid hormone receptor interactor 6	0.015
Tnxb	tenascin XB	0.015
Igfbp7	insulin-like growth factor binding protein 7	0.015
Gpc3	glypican 3	0.015
Bmp1	bone morphogenetic protein 1	0.015
Ch25h	cholesterol 25-hydroxylase	0.014
Lama2	laminin, alpha 2	0.014
Cldn5	claudin 5	0.014
Plvap	plasmalemma vesicle associated protein	0.014
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.013
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.013
Col4a4	collagen, type IV, alpha 4	0.013
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.013
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.013
Tfpi2	tissue factor pathway inhibitor 2	0.013
Llgl1	lethal giant larvae homolog 1 (Drosophila)	0.013
Plxnd1	plexin D1	0.013
Ramp2	receptor (calcitonin) activity modifying protein 2	0.012
Col16a1	collagen, type XVI, alpha 1	0.012
Aplnr	apelin receptor	0.012
Aoc3	amine oxidase, copper containing 3	0.012
Ikzf4	IKAROS family zinc finger 4	0.012
Tmem204	transmembrane protein 204	0.012
Kank3	KN motif and ankyrin repeat domains 3	0.012
Procr	protein C receptor, endothelial	0.012
Apom	apolipoprotein M	0.012
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.012
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.012
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.012
Prx	periaxin	0.012
C3	complement component 3	0.011
Osmr	oncostatin M receptor	0.011
Myo6	myosin VI	0.011
Prodh2	proline dehydrogenase (oxidase) 2	0.011
Pzp	pregnancy zone protein	0.011
Sod3	superoxide dismutase 3, extracellular	0.011
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.011
Fzd1	frizzled homolog 1 (Drosophila)	0.011
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.011
Ldb2	LIM domain binding 2	0.011
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.011
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.011
Ccl17	chemokine (C-C motif) ligand 17	0.011
Upk3b	uroplakin 3B	0.011
Actn1	actinin, alpha 1	0.011
Blnk	B-cell linker	0.011
Arsi	arylsulfatase i	0.011
Tnip1	TNFAIP3 interacting protein 1	0.011
Vegfc	vascular endothelial growth factor C	0.011
Ccl7	chemokine (C-C motif) ligand 7	0.011
Socs3	suppressor of cytokine signaling 3	0.011
Calcrl	calcitonin receptor-like	0.011
Cfi	complement component factor i	0.011
Tagln	transgelin	0.011
Pbx1	pre B-cell leukemia transcription factor 1	0.011
Bhlhe40	basic helix-loop-helix family, member e40	0.011
Itga8	integrin alpha 8	0.011
Actn4	actinin alpha 4	0.010
Chd7	chromodomain helicase DNA binding protein 7	0.010
Vav3	vav 3 oncogene	0.010
Sox7	SRY-box containing gene 7	0.010
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.010
Hoxb6	homeobox B6	0.010
Thbs2	thrombospondin 2	0.010
Hspa1b	heat shock protein 1B	0.010