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Process View

Mus musculus

15 genes annotated in mouse

segment specification

The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "segment specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "segment specification" (in gray)

Name	Description	Probability	Func Analog Organism
Notch1	Notch gene homolog 1 (Drosophila)	1.000
Vangl2	vang-like 2 (van gogh, Drosophila)	0.999
Psen1	presenilin 1	0.996
Dll1	delta-like 1 (Drosophila)	0.980
Foxc1	forkhead box C1	0.979	Fly
Rnf2	ring finger protein 2	0.965
Pax2	paired box gene 2	0.964
Eya1	eyes absent 1 homolog (Drosophila)	0.950
Hoxa3	homeobox A3	0.940
Foxg1	forkhead box G1	0.936
Pax3	paired box gene 3	0.929
Foxc2	forkhead box C2	0.923	Fly
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.920
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.907
Emx2	empty spiracles homolog 2 (Drosophila)	0.906
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.901
Jag1	jagged 1	0.854	Mouse
Hoxa1	homeobox A1	0.828	Mouse Fly
Hoxb2	homeobox B2	0.813	Mouse Fly
Stat5b	signal transducer and activator of transcription 5B	0.811	Fly
Gata3	GATA binding protein 3	0.774
Chd7	chromodomain helicase DNA binding protein 7	0.773	Fly
Notch2	Notch gene homolog 2 (Drosophila)	0.747
Tbx1	T-box 1	0.737
Pitx2	paired-like homeodomain transcription factor 2	0.732
Uncx	UNC homeobox	0.666
Hoxd3	homeobox D3	0.664
Rb1	retinoblastoma 1	0.622
Fgf8	fibroblast growth factor 8	0.619
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.616	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.583	Mouse
Jarid2	jumonji, AT rich interactive domain 2	0.505
Ednra	endothelin receptor type A	0.500
Vangl1	vang-like 1 (van gogh, Drosophila)	0.478
Hoxb1	homeobox B1	0.468	Mouse Fly
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.448
Irx5	Iroquois related homeobox 5 (Drosophila)	0.445	Mouse
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.437
Sox2	SRY-box containing gene 2	0.396
Otx2	orthodenticle homolog 2 (Drosophila)	0.396
Fgfr1	fibroblast growth factor receptor 1	0.395
Hoxa2	homeobox A2	0.390
Stat5a	signal transducer and activator of transcription 5A	0.385	Fly
Gli3	GLI-Kruppel family member GLI3	0.374
Pax1	paired box gene 1	0.369
Tbx10	T-box 10	0.340
Ptk7	PTK7 protein tyrosine kinase 7	0.326
Gbx2	gastrulation brain homeobox 2	0.326
Hoxb3	homeobox B3	0.309
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.283	Zebrafish
Emx1	empty spiracles homolog 1 (Drosophila)	0.282
Rybp	RING1 and YY1 binding protein	0.245
Tbx6	T-box 6	0.244
Stat3	signal transducer and activator of transcription 3	0.243
Hmx3	H6 homeobox 3	0.238
Rarg	retinoic acid receptor, gamma	0.237
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.234	Fly
Dll3	delta-like 3 (Drosophila)	0.231	Zebrafish Mouse
Mecom	MDS1 and EVI1 complex locus	0.229
T	brachyury	0.216
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.214	Mouse
Nog	noggin	0.213
Shh	sonic hedgehog	0.205
Hes3	hairy and enhancer of split 3 (Drosophila)	0.203	Mouse
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.199
Pcgf2	polycomb group ring finger 2	0.196
Hoxb6	homeobox B6	0.191
Neurog1	neurogenin 1	0.185
Lmx1a	LIM homeobox transcription factor 1 alpha	0.185
Efnb2	ephrin B2	0.163
Tcf15	transcription factor 15	0.162
Hoxd13	homeobox D13	0.160
Ctnnb1	catenin (cadherin associated protein), beta 1	0.159
Gsc	goosecoid homeobox	0.156
Rxra	retinoid X receptor alpha	0.155
H3f3a	H3 histone, family 3A	0.142
Isl1	ISL1 transcription factor, LIM/homeodomain	0.142
Fgf10	fibroblast growth factor 10	0.140
Tcfap2a	transcription factor AP-2, alpha	0.135
Trp53	transformation related protein 53	0.135
Bcor	BCL6 interacting corepressor	0.133
Foxp3	forkhead box P3	0.129
Rbbp4	retinoblastoma binding protein 4	0.124	Fly
Hes5	hairy and enhancer of split 5 (Drosophila)	0.117
Hoxa13	homeobox A13	0.111
Meox2	mesenchyme homeobox 2	0.110
Rara	retinoic acid receptor, alpha	0.107
Jag2	jagged 2	0.100	Mouse
En1	engrailed 1	0.098
Wnt3a	wingless-related MMTV integration site 3A	0.096
Hmx1	H6 homeobox 1	0.092
Dlx5	distal-less homeobox 5	0.092
Dll4	delta-like 4 (Drosophila)	0.088	Mouse
Snai1	snail homolog 1 (Drosophila)	0.087
Hand2	heart and neural crest derivatives expressed transcript 2	0.083
Irx1	Iroquois related homeobox 1 (Drosophila)	0.080
Pitx3	paired-like homeodomain transcription factor 3	0.077
Tlx3	T-cell leukemia, homeobox 3	0.074
Ikbkb	inhibitor of kappaB kinase beta	0.073
Zeb1	zinc finger E-box binding homeobox 1	0.073
Il4ra	interleukin 4 receptor, alpha	0.071
Ptf1a	pancreas specific transcription factor, 1a	0.071
Sox3	SRY-box containing gene 3	0.070
Hoxd11	homeobox D11	0.070
Zfp503	zinc finger protein 503	0.068
Wnt6	wingless-related MMTV integration site 6	0.068
Hoxd1	homeobox D1	0.064	Mouse Fly
Pax6	paired box gene 6	0.063
Irx3	Iroquois related homeobox 3 (Drosophila)	0.062
Otx1	orthodenticle homolog 1 (Drosophila)	0.061
Lhx5	LIM homeobox protein 5	0.060
Sall3	sal-like 3 (Drosophila)	0.060
Phc2	polyhomeotic-like 2 (Drosophila)	0.059
Hmga1	high mobility group AT-hook 1	0.059
Foxn1	forkhead box N1	0.059
Psen2	presenilin 2	0.059
Hmx2	H6 homeobox 2	0.058
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.058
Hoxa5	homeobox A5	0.058
Pten	phosphatase and tensin homolog	0.057
Stk38	serine/threonine kinase 38	0.056
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.055
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.054
Cnga3	cyclic nucleotide gated channel alpha 3	0.054
Ring1	ring finger protein 1	0.053
D930020E02Rik	RIKEN cDNA D930020E02 gene	0.053
Sox11	SRY-box containing gene 11	0.050
Foxf1a	forkhead box F1a	0.048
Efna2	ephrin A2	0.048
Mesp2	mesoderm posterior 2	0.047	Mouse
Irx2	Iroquois related homeobox 2 (Drosophila)	0.045
Bmi1	Bmi1 polycomb ring finger oncogene	0.045
Phlda2	pleckstrin homology-like domain, family A, member 2	0.045
Pitx1	paired-like homeodomain transcription factor 1	0.044
Fgf15	fibroblast growth factor 15	0.043
Tcfap2c	transcription factor AP-2, gamma	0.042
Hoxb4	homeobox B4	0.042	Fly
Ikbkg	inhibitor of kappaB kinase gamma	0.042
Neurog2	neurogenin 2	0.041
Fosl2	fos-like antigen 2	0.040
Hoxb5	homeobox B5	0.039
Ebf3	early B-cell factor 3	0.039	Fly
Zfp36	zinc finger protein 36	0.037
Fgf3	fibroblast growth factor 3	0.037
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.036
Pax7	paired box gene 7	0.035
Pdx1	pancreatic and duodenal homeobox 1	0.035
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.035
Lhx3	LIM homeobox protein 3	0.034
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.034
Hoxd9	homeobox D9	0.034
Hoxa7	homeobox A7	0.033
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.033	Fly
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.033
Krt15	keratin 15	0.033
Plac1	placental specific protein 1	0.032
Smad3	MAD homolog 3 (Drosophila)	0.032
Myf5	myogenic factor 5	0.031
Barx1	BarH-like homeobox 1	0.029
Foxd3	forkhead box D3	0.029
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.028
Pou3f4	POU domain, class 3, transcription factor 4	0.028
Hoxb9	homeobox B9	0.028
Tgfbr2	transforming growth factor, beta receptor II	0.028
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.028
Zbtb7a	zinc finger and BTB domain containing 7a	0.027
Vax1	ventral anterior homeobox containing gene 1	0.027
Gata6	GATA binding protein 6	0.026
Trp73	transformation related protein 73	0.026
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.025
Cilp2	cartilage intermediate layer protein 2	0.025
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.025
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.025
Nkx3-2	NK3 homeobox 2	0.024
Nrarp	Notch-regulated ankyrin repeat protein	0.024
Btbd17	BTB (POZ) domain containing 17	0.024
Tnnc2	troponin C2, fast	0.023
Cbx3	chromobox homolog 3 (Drosophila HP1 gamma)	0.023
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.023
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.023
Hoxc6	homeobox C6	0.022
Kdm2b	lysine (K)-specific demethylase 2B	0.022	Fly
Tnnt3	troponin T3, skeletal, fast	0.022
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.022
Gata4	GATA binding protein 4	0.022
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.022
Foxo1	forkhead box O1	0.021
Ubtf	upstream binding transcription factor, RNA polymerase I	0.021
Ager	advanced glycosylation end product-specific receptor	0.021
Prph	peripherin	0.021
Tbx18	T-box18	0.020
Mnx1	motor neuron and pancreas homeobox 1	0.020
Wnt1	wingless-related MMTV integration site 1	0.020
Evx2	even skipped homeotic gene 2 homolog	0.020
Gabrr2	gamma-aminobutyric acid (GABA) C receptor, subunit rho 2	0.020
Prph2	peripherin 2	0.020
Nkx6-1	NK6 homeobox 1	0.019
Junb	Jun-B oncogene	0.019
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.019
Efnb1	ephrin B1	0.019
Myog	myogenin	0.019
Padi3	peptidyl arginine deiminase, type III	0.019
Mll2	myeloid/lymphoid or mixed-lineage leukemia 2	0.019
Pvr	poliovirus receptor	0.019
Dlx2	distal-less homeobox 2	0.019
Tgfbr3	transforming growth factor, beta receptor III	0.019
Zbtb12	zinc finger and BTB domain containing 12	0.019
Hoxa9	homeobox A9	0.018
Hoxc8	homeobox C8	0.018
Mybph	myosin binding protein H	0.018
Wnt2b	wingless related MMTV integration site 2b	0.018
Socs1	suppressor of cytokine signaling 1	0.018
Myl3	myosin, light polypeptide 3	0.018
Chd8	chromodomain helicase DNA binding protein 8	0.018	Fly
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.018
Col13a1	collagen, type XIII, alpha 1	0.018
Hoxa4	homeobox A4	0.018	Fly
Fgfr2	fibroblast growth factor receptor 2	0.017
Twist1	twist homolog 1 (Drosophila)	0.017
Rhox6	reproductive homeobox 6	0.017
Noto	notochord homolog (Xenopus laevis)	0.017
Bnc1	basonuclin 1	0.016
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.016
Sox1	SRY-box containing gene 1	0.016
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.016
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.016
Hoxc4	homeobox C4	0.016	Fly
Pou4f3	POU domain, class 4, transcription factor 3	0.016
Ikzf2	IKAROS family zinc finger 2	0.016
Klf3	Kruppel-like factor 3 (basic)	0.016
Efna4	ephrin A4	0.016
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.016
Tulp1	tubby like protein 1	0.015
Lhx1	LIM homeobox protein 1	0.015
Zbtb33	zinc finger and BTB domain containing 33	0.015
Cldn6	claudin 6	0.015
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.015
Nkd1	naked cuticle 1 homolog (Drosophila)	0.015
Fzd1	frizzled homolog 1 (Drosophila)	0.015
Zfp865	zinc finger protein 865	0.015
Esr2	estrogen receptor 2 (beta)	0.015
Itch	itchy, E3 ubiquitin protein ligase	0.014
Foxd2	forkhead box D2	0.014
Zfp703	zinc finger protein 703	0.014
Magel2	melanoma antigen, family L, 2	0.014
Siah1a	seven in absentia 1A	0.014
Tbx4	T-box 4	0.014
Rax	retina and anterior neural fold homeobox	0.014
Ezh1	enhancer of zeste homolog 1 (Drosophila)	0.014
Il3	interleukin 3	0.014
Hesx1	homeobox gene expressed in ES cells	0.014
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.014
Sfrp2	secreted frizzled-related protein 2	0.014
Ntn1	netrin 1	0.013
Hoxc9	homeobox C9	0.013
Pax9	paired box gene 9	0.013
Epha2	Eph receptor A2	0.013
Aebp2	AE binding protein 2	0.013	Fly
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.013
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.013
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.013
Phc3	polyhomeotic-like 3 (Drosophila)	0.013
Sema6c	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.013
Krtap3-3	keratin associated protein 3-3	0.013
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.012
Glis1	GLIS family zinc finger 1	0.012
Egfr	epidermal growth factor receptor	0.012
Myoz1	myozenin 1	0.012
Npr3	natriuretic peptide receptor 3	0.012
Dlx1	distal-less homeobox 1	0.012
Hoxd10	homeobox D10	0.012
Twist2	twist homolog 2 (Drosophila)	0.012
Pyy	peptide YY	0.012
Mesp1	mesoderm posterior 1	0.012	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.012
Nrk	Nik related kinase	0.012
Efnb3	ephrin B3	0.012
Lox	lysyl oxidase	0.011
Zic2	zinc finger protein of the cerebellum 2	0.011
Crabp1	cellular retinoic acid binding protein I	0.011
Sct	secretin	0.011
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.011
Skil	SKI-like	0.011
Hrc	histidine rich calcium binding protein	0.011
Ece1	endothelin converting enzyme 1	0.011
Gcm1	glial cells missing homolog 1 (Drosophila)	0.011
Fgf17	fibroblast growth factor 17	0.011
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.011
Jun	Jun oncogene	0.011
Hoxd4	homeobox D4	0.011	Fly
Ephb2	Eph receptor B2	0.011
Grik3	glutamate receptor, ionotropic, kainate 3	0.011
Sox4	SRY-box containing gene 4	0.011
Evx1	even skipped homeotic gene 1 homolog	0.011
Cdh4	cadherin 4	0.011
Sult1c1	sulfotransferase family, cytosolic, 1C, member 1	0.011
Hoxa10	homeobox A10	0.011
Ntn3	netrin 3	0.011
Pofut1	protein O-fucosyltransferase 1	0.011
Pcdh12	protocadherin 12	0.011
Ptch1	patched homolog 1	0.010
Atoh7	atonal homolog 7 (Drosophila)	0.010
Gucy2d	guanylate cyclase 2d	0.010
Sox14	SRY-box containing gene 14	0.010