IMP

Process View

Danio rerio

3 genes annotated in zebrafish

atrioventricular valve formation

The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "atrioventricular valve formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "atrioventricular valve formation" (in gray)

Name	Description	Probability	Func Analog Organism
tal1	T-cell acute lymphocytic leukemia 1	0.982
hnf1ba	HNF1 homeobox Ba	0.974
tbx5a	T-box 5a	0.958
tbx20	T-box 20	0.955	Zebrafish
tbx16	T-box gene 16	0.952	Zebrafish
gata6	GATA-binding protein 6	0.938
hand2	heart and neural crest derivatives expressed transcript 2	0.917
pax2a	paired box gene 2a	0.899
tbx1	T-box 1	0.895	Zebrafish
bmp4	bone morphogenetic protein 4	0.894
kdrl	kinase insert domain receptor like	0.884
nkx2.5	NK2 transcription factor related 5	0.759
tbx18	T-box 18	0.707	Zebrafish
hhex	hematopoietically expressed homeobox	0.684
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.683
fgf8a	fibroblast growth factor 8 a	0.651
cdh2	cadherin 2, neuronal	0.644
fli1a	friend leukemia integration 1a	0.633
gata2a	GATA-binding protein 2a	0.625
cdx4	caudal type homeo box transcription factor 4	0.598
tbx2a	T-box gene 2a	0.574	Zebrafish
ntla	no tail a	0.572	Zebrafish
flh	floating head	0.561
gata5	GATA-binding protein 5	0.550	Zebrafish
myl7	myosin, light polypeptide 7, regulatory	0.531
lhx1a	LIM homeobox 1a	0.516
bmp2b	bone morphogenetic protein 2b	0.514
shha	sonic hedgehog a	0.489
has2	hyaluronan synthase 2	0.483
wnt11	wingless-type MMTV integration site family, member 11	0.476
lft2	lefty2	0.466
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.431	Mouse
her7	hairy and enhancer of split related-7	0.431
oep	one-eyed pinhead	0.429
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.403
dld	deltaD	0.383
ptch1	patched 1	0.371
gata1a	GATA binding protein 1a	0.368	Zebrafish
isl1	islet1	0.356
chd	chordin	0.353
foxh1	forkhead box H1	0.340
tcf21	transcription factor 21	0.323
runx1	runt-related transcription factor 1	0.308
pitx2	paired-like homeodomain transcription factor 2	0.284
notch1b	notch homolog 1b	0.275	Human
dlx2a	distal-less homeobox gene 2a	0.275
drl	draculin	0.265
fn1	fibronectin 1	0.253
her1	hairy-related 1	0.252
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.244
myod1	myogenic differentiation 1	0.238
dlc	deltaC	0.229
crip2	cysteine-rich protein 2	0.212
foxa1	forkhead box A1	0.212
foxi1	forkhead box I1	0.205
otx2	orthodenticle homolog 2	0.202
tbx6	T-box gene 6	0.194	Zebrafish
mib	mind bomb	0.180
notch1a	notch homolog 1a	0.175	Human
pou5f1	POU domain, class 5, transcription factor 1	0.174
lmo2	LIM domain only 2 (rhombotin-like 1)	0.165
znfl2a	zinc finger-like gene 2a	0.163
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.155
myf5	myogenic factor 5	0.154
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.149
nppa	natriuretic peptide precursor A	0.138
pcdh8	protocadherin 8	0.137
barhl2	BarH-like 2	0.126
tbx24	T-box 24	0.125	Zebrafish
irx3a	iroquois homeobox protein 3a	0.125
ndr2	nodal-related 2	0.123
nkx2.2a	NK2 transcription factor related 2a	0.123
foxn4	forkhead box N4	0.120
lft1	lefty1	0.119
sox32	SRY-box containing gene 32	0.119
klf2a	Kruppel-like factor 2a	0.117
isl2a	islet2a	0.114
eve1	even-skipped-like1	0.114
fgf10a	fibroblast growth factor 10a	0.113
olfm2	olfactomedin 2	0.110
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.107
tfap2a	transcription factor AP-2 alpha	0.105
hoxb1b	homeo box B1b	0.105
foxa3	forkhead box A3	0.101
mef2cb	myocyte enhancer factor 2cb	0.101
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.092
trim33	tripartite motif-containing 33	0.089
lhx5	LIM homeobox 5	0.089
etv2	ets variant gene 2	0.086
prox1	prospero-related homeobox gene 1	0.086
cmlc1	cardiac myosin light chain-1	0.084
osr1	odd-skipped related 1 (Drosophila)	0.084
msgn1	mesogenin 1	0.081
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.081
osr2	odd-skipped related 2 (Drosophila)	0.080
jag2	jagged 2	0.079
meis3	myeloid ecotropic viral integration site 3	0.078
hspb12	heat shock protein, alpha-crystallin-related, b12	0.077
wnt9a	wingless-type MMTV integration site family, member 9A	0.074
rx3	retinal homeobox gene 3	0.072
pkd2	polycystic kidney disease 2	0.068
rnasel1	ribonuclease like 1	0.067
neo1	neogenin 1	0.067
aplnrb	apelin receptor b	0.066
irx1a	iroquois homeobox protein 1, a	0.066
rbm24a	RNA binding motif protein 24a	0.065
eomesa	eomesodermin homolog a	0.063	Zebrafish
hoxd11a	homeo box D11a	0.061
foxa2	forkhead box A2	0.059
bmp2a	bone morphogenetic protein 2a	0.059
ndrg4	N-myc downstream regulated gene 4	0.058
LOC566708	FL cytokine receptor-like	0.058
sulf1	sulfatase 1	0.057
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.057
notch2	notch homolog 2	0.056
ttna	titin a	0.056
hoxa9b	homeo box A9b	0.056
gja3	gap junction protein, alpha 3	0.055
tnni1b	troponin I, skeletal, slow b	0.055
hoxa9a	homeo box A9a	0.053
sox10	SRY-box containing gene 10	0.053
cdh5	cadherin 5	0.052
six3a	sine oculis homeobox homolog 3a	0.051
ndr1	nodal-related 1	0.051
gfi1.1	growth factor independent 1.1	0.051
six4b	sine oculis homeobox homolog 4b	0.050
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.050
scube2	signal peptide, CUB domain, EGF-like 2	0.050
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.048
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.048
tnnc1a	troponin C type 1a (slow)	0.048
foxc1a	forkhead box C1a	0.047
bmper	BMP binding endothelial regulator	0.047
foxd3	forkhead box D3	0.046
spaw	southpaw	0.046
dlx4b	distal-less homeobox gene 4b	0.046
smyd1b	SET and MYND domain containing 1b	0.046
gata3	GATA-binding protein 3	0.046	Zebrafish
gbx2	gastrulation brain homeo box 2	0.045
raraa	retinoic acid receptor, alpha a	0.045
tp63	tumor protein p63	0.045
lmo4a	LIM domain only 4a	0.044
wnt11r	wingless-type MMTV integration site family, member 11, related	0.044
hoxc8a	homeo box C8a	0.043
ins	preproinsulin	0.043
fzd10	frizzled homolog 10	0.042
zic4	zic family member 4	0.040
wnt5b	wingless-type MMTV integration site family, member 5b	0.040
tbx5b	T-box 5b	0.040
hoxd13a	homeo box D13a	0.039
tp53	tumor protein p53	0.039
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.039
otx1b	orthodenticle homolog 1b	0.039
vasa	vasa homolog	0.039
lmna	lamin A	0.039
hoxd12a	homeo box D12a	0.038
cmyb	transcription factor cmyb	0.038
gamt	guanidinoacetate N-methyltransferase	0.038
trpv4	transient receptor potential cation channel, subfamily V, member 4	0.038
dlx3b	distal-less homeobox gene 3b	0.037
vent	ventral expressed homeobox	0.037
tll1	tolloid-like 1	0.037
sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.037
bcdo2l	beta-carotene 15, 15-dioxygenase 2, like	0.037
slc25a37	solute carrier family 25, member 37	0.037
gli2a	GLI-Kruppel family member GLI2a	0.036
col12a1	collagen, type XII, alpha 1	0.035
hoxa10b	homeo box A10b	0.035
hoxa11a	homeo box A11a	0.035
klf4	Kruppel-like factor 4	0.035
nkx2.3	NK2 transcription factor related 3	0.035
vsx2	visual system homeobox 2	0.035
vmhc	ventricular myosin heavy chain	0.035
prrx1b	paired related homeobox 1b	0.035
sp5l	Sp5 transcription factor-like	0.033
dcc	deleted in colorectal carcinoma	0.033
tjp1	tight junction protein 1 (zona occludens 1)	0.032
esr1	estrogen receptor 1	0.032
dusp5	dual specificity phosphatase 5	0.032
prdm1a	PR domain containing 1a, with ZNF domain	0.032
mnx1	motor neuron and pancreas homeobox 1	0.032
wnt8a	wingless-type MMTV integration site family, member 8a	0.032
sp5	Sp5 transcription factor	0.031
vox	ventral homeobox	0.031
twist1a	twist1a	0.031
pcdh10b	protocadherin 10b	0.031
dlx5a	distal-less homeobox gene 5a	0.030
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.030
si:ch73-60e21.1	si:ch73-60e21.1	0.029
wt1a	wilms tumor 1a	0.029
pdlim2	PDZ and LIM domain 2 (mystique)	0.029
tgfb3	transforming growth factor, beta 3	0.029
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.029
fhla	four and a half LIM domains a	0.029
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.029
lrrc6	leucine rich repeat containing 6	0.028
atp2a2a	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a	0.028
sox4b	SRY-box containing gene 4b	0.028
jag1b	jagged 1b	0.028
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.028
ptch2	patched 2	0.028
hes6	hairy and enhancer of split 6 (Drosophila)	0.027
mef2ca	myocyte enhancer factor 2ca	0.026
nanos3	nanos homolog 3	0.026
rp42-pen	rp42 homolog (pending) and rp42 homolog	0.026
lamb1a	laminin, beta 1a	0.025
wu:fb01h12	wu:fb01h12	0.025
bmp3	bone morphogenetic protein 3	0.025
foxd5	forkhead box D5	0.025
ihha	Indian hedgehog homolog a	0.025
apc	adenomatosis polyposis coli	0.025
dlx6a	distal-less homeobox gene 6a	0.025
vcana	versican a	0.024
metap2	methionyl aminopeptidase 2	0.024
hoxd10a	homeo box D10a	0.024
prrx1a	paired related homeobox 1a	0.024
lhx1b	LIM homeobox 1b	0.024
mespa	mesoderm posterior a	0.024
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.023
LOC100151531	zinc finger protein Gfi-1b-like	0.023
rag1	recombination activating gene 1	0.023
vangl2	vang-like 2 (van gogh, Drosophila)	0.023
pax6a	paired box gene 6a	0.023
gdf6b	growth differentiation factor 6b	0.023
limk1	LIM domain kinase 1	0.023
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.022
tie1	endothelium-specific receptor tyrosine kinase 1	0.022
tfr1a	transferrin receptor 1a	0.022
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.022
pdlim4	PDZ and LIM domain 4	0.022
trim3a	tripartite motif-containing 3a	0.021
foxg1a	forkhead box G1a	0.021
gsc	goosecoid	0.021
szl	sizzled	0.021
evx1	even-skipped homeobox 1	0.021
ptgs1	prostaglandin-endoperoxide synthase 1	0.021
snai1a	snail homolog 1a (Drosophila)	0.021
hspb1	heat shock protein, alpha-crystallin-related, 1	0.021
wt1b	wilms tumor 1b	0.020
zic6	zic family member 6	0.020
zeb1	zinc finger E-box binding homeobox 1	0.020
twist3	twist3	0.020
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.020
tp73	tumor protein p73	0.020
axin1	axin 1	0.019
her6	hairy-related 6	0.019
msxc	muscle segment homeobox C	0.019
gata4	GATA-binding protein 4	0.019	Zebrafish Mouse
pdlim3b	PDZ and LIM domain 3b	0.019
fbp1b	fructose-1,6-bisphosphatase 1b	0.018
LOC100001530	isotocin receptor-like 2	0.018
alcama	activated leukocyte cell adhesion molecule a	0.018
zgc:111821	zgc:111821	0.018
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.018
rarab	retinoic acid receptor, alpha b	0.018
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.018
supt6h	suppressor of Ty 6 homolog	0.017
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.017
cldng	claudin g	0.017
alas2	aminolevulinate, delta-, synthetase 2	0.017
rest	RE1-silencing transcription factor	0.017
hoxd9a	homeo box D9a	0.017
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.017
fzd8a	frizzled homolog 8a	0.016
slc8a1a	solute carrier family 8 (sodium/calcium exchanger), member 1a	0.016
shhb	sonic hedgehog b	0.016
fgfr4	fibroblast growth factor receptor 4	0.016
loxl3b	lysyl oxidase-like 3b	0.016
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.016
f2r	coagulation factor II (thrombin) receptor	0.016
irf6	interferon regulatory factor 6	0.016
hoxb5a	homeo box B5a	0.016
fezf2	FEZ family zinc finger 2	0.016
siah1	seven in absentia homolog 1 (Drosophila)	0.016
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.016
olig2	oligodendrocyte lineage transcription factor 2	0.016
dla	deltaA	0.016
si:ch211-235f6.2	si:ch211-235f6.2	0.016
tbx3	T-box 3	0.016	Zebrafish
dharma	dharma	0.015
dachb	dachshund b	0.015
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.015
pdlim3a	PDZ and LIM domain 3a	0.015
stab2	stabilin 2	0.015
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.014
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.014
si:dkeyp-66d7.2	si:dkeyp-66d7.2	0.014
tbx2b	T-box 2b	0.014	Zebrafish
sox9b	SRY-box containing gene 9b	0.014
cpox	coproporphyrinogen oxidase	0.014
aldob	aldolase b, fructose-bisphosphate	0.014
lama4	laminin, alpha 4	0.014
tgfb2	transforming growth factor, beta 2	0.014
col9a2	procollagen, type IX, alpha 2	0.014
lef1	lymphocyte enhancer binding factor 1	0.014
scn12ab	sodium channel, voltage gated, type XII, alpha b	0.014
nr5a2	nuclear receptor subfamily 5, group A, member 2	0.014
mecom	MDS1 and EVI1 complex locus	0.014
bmp7a	bone morphogenetic protein 7a	0.014
gdf6a	growth differentiation factor 6a	0.014
tph2	tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)	0.014
flt4	fms-related tyrosine kinase 4	0.014
cx43	connexin 43	0.014
sox17	SRY-box containing gene 17	0.013
traf4a	tnf receptor-associated factor 4a	0.013
gli1	GLI-Kruppel family member 1	0.013
notch3	notch homolog 3	0.013
vsx1	visual system homeobox 1 homolog, chx10-like	0.013
pax9	paired box gene 9	0.013
krt5	keratin 5	0.013
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.013
rbm24b	RNA binding motif protein 24b	0.013
mespb	mesoderm posterior b	0.013
stat1b	signal transducer and activator of transcription 1b	0.013
and1	actinodin1	0.013
fancd2	Fanconi anemia, complementation group D2	0.013
tfeb	transcription factor EB	0.013
cd8a	CD8 antigen, alpha polypeptide	0.013
sf3b1	splicing factor 3b, subunit 1	0.013
nkx2.2b	NK2 transcription factor related 2b	0.013
nos1	nitric oxide synthase 1 (neuronal)	0.013
dlx1a	distal-less homeobox gene 1a	0.013
tmem88a	transmembrane protein 88 a	0.013
elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.012
ihhb	Indian hedgehog homolog b	0.012
rgma	RGM domain family, member A	0.012
pdcd2	programmed cell death 2	0.012
plagx	pleiomorphic adenoma gene X	0.012
LOC565649	FYVE and coiled-coil domain-containing protein 1-like	0.012
cbfb	core-binding factor, beta subunit	0.012
desma	desmin a	0.012
rhoua	ras homolog gene family, member Ua	0.012
gmcl1	germ cell-less homolog 1 (Drosophila)	0.012
plag1	pleiomorphic adenoma gene 1	0.012
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.012
ogg1	8-oxoguanine DNA glycosylase	0.012
mib2	mind bomb 2	0.012
zgc:63938	zgc:63938	0.012
smyd3	SET and MYND domain containing 3	0.012
rxrga	retinoid x receptor, gamma a	0.012
neurod6b	neurogenic differentiation 6b	0.012
ifnphi1	interferon phi 1	0.012
pdcd4b	programmed cell death 4b	0.012
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.012
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.011
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.011
amotl2a	angiomotin like 2a	0.011
tie2	endothelium-specific receptor tyrosine kinase 2	0.011
agfg1a	ArfGAP with FG repeats 1a	0.011
fabp2	fatty acid binding protein 2, intestinal	0.011
ptprb	protein tyrosine phosphatase, receptor type, b	0.011
runx2b	runt-related transcription factor 2b	0.011
barx1	BarH-like homeobox 1	0.011
e2f7	E2F transcription factor 7	0.011
pth2	parathyroid hormone 2	0.011
hoxa13a	homeo box A13a	0.011
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.011
irx7	iroquois homeobox protein 7	0.011
dbx1b	developing brain homeobox 1b	0.011
zgc:161979	zgc:161979	0.011
gpia	glucose phosphate isomerase a	0.011
fetub	fetuin B	0.011
nkx2.1b	NK2 homeobox 1b	0.011
gro2	groucho 2	0.011
cyp2p6	cytochrome P450, family 2, subfamily P, polypeptide 6	0.011
ctbp2	C-terminal binding protein 2	0.011
gdnf	glial cell derived neurotrophic factor	0.010
dll4	delta-like 4 (Drosophila)	0.010
vcanb	versican b	0.010
col8a1a	collagen, type VIII, alpha 1a	0.010
spon1b	spondin 1b	0.010
cdh1	cadherin 1, epithelial	0.010
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.010
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.010
mbtps1	membrane-bound transcription factor protease, site 1	0.010
hbbe1.1	hemoglobin beta embryonic-1.1	0.010