Process View
The network for 'organ morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
EGFR | epidermal growth factor receptor | 1.000 | |
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1.000 | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 1.000 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | |
TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 1.000 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 1.000 | |
ESR1 | estrogen receptor 1 | 1.000 | |
TP53 | tumor protein p53 | 1.000 | |
YAP1 | Yes-associated protein 1 | 0.999 | |
FLNA | filamin A, alpha | 0.999 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.999 | |
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.999 | |
FN1 | fibronectin 1 | 0.998 | |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.998 | |
SP1 | Sp1 transcription factor | 0.997 | |
CDK2 | cyclin-dependent kinase 2 | 0.997 | |
CREBBP | CREB binding protein | 0.997 | |
NCOR1 | nuclear receptor corepressor 1 | 0.996 | |
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.994 | |
FGFR2 | fibroblast growth factor receptor 2 | 0.994 | |
SMAD2 | SMAD family member 2 | 0.994 | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.993 | |
SFN | stratifin | 0.992 | |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.991 | |
HDAC1 | histone deacetylase 1 | 0.990 | |
MYOD1 | myogenic differentiation 1 | 0.987 | |
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.986 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.986 | |
RUNX1 | runt-related transcription factor 1 | 0.984 | |
TAL1 | T-cell acute lymphocytic leukemia 1 | 0.979 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.976 | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.976 | |
MYH9 | myosin, heavy chain 9, non-muscle | 0.975 | |
THBS1 | thrombospondin 1 | 0.972 | |
CTGF | connective tissue growth factor | 0.972 | |
NOTCH1 | notch 1 | 0.971 | |
PDX1 | pancreatic and duodenal homeobox 1 | 0.966 | |
JAG1 | jagged 1 | 0.966 | |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.964 | |
HDAC2 | histone deacetylase 2 | 0.962 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.962 | |
COL1A1 | collagen, type I, alpha 1 | 0.957 | |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.955 | |
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.953 | |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.952 | |
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.949 | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.946 | |
MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.943 | |
YY1 | YY1 transcription factor | 0.942 | |
TP63 | tumor protein p63 | 0.941 | |
SMAD7 | SMAD family member 7 | 0.940 | |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.935 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.935 | |
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.933 | |
HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.930 | |
RB1 | retinoblastoma 1 | 0.925 | |
FGF1 | fibroblast growth factor 1 (acidic) | 0.924 | |
CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.918 | |
TCF4 | transcription factor 4 | 0.917 | |
SMAD4 | SMAD family member 4 | 0.915 | |
DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.913 | |
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.909 | |
AR | androgen receptor | 0.908 | |
DDX3X | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 0.905 | |
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.901 | |
NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.897 | |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.894 | |
FGFR1 | fibroblast growth factor receptor 1 | 0.893 | |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.891 | |
GATA4 | GATA binding protein 4 | 0.891 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.889 | |
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.884 | |
HOXB5 | homeobox B5 | 0.883 | |
POU3F2 | POU class 3 homeobox 2 | 0.882 | |
CDK6 | cyclin-dependent kinase 6 | 0.881 | |
RBBP4 | retinoblastoma binding protein 4 | 0.880 | |
VEGFA | vascular endothelial growth factor A | 0.876 | |
KLK10 | kallikrein-related peptidase 10 | 0.870 | |
EPAS1 | endothelial PAS domain protein 1 | 0.868 | |
NOTCH3 | notch 3 | 0.868 | |
GRB7 | growth factor receptor-bound protein 7 | 0.868 | |
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.867 | |
PPARA | peroxisome proliferator-activated receptor alpha | 0.864 | |
CCND1 | cyclin D1 | 0.862 | |
COL1A2 | collagen, type I, alpha 2 | 0.851 | |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.848 | |
NRP1 | neuropilin 1 | 0.848 | |
TP73 | tumor protein p73 | 0.847 | |
FHL2 | four and a half LIM domains 2 | 0.847 | |
FOXA2 | forkhead box A2 | 0.841 | |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.840 | |
PAX7 | paired box 7 | 0.837 | |
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.832 | |
CDX2 | caudal type homeobox 2 | 0.831 | |
SCHIP1 | schwannomin interacting protein 1 | 0.829 | |
BCOR | BCL6 corepressor | 0.828 | |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.828 | |
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.827 | |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.825 | |
CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.824 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
pha-4 | Protein PHA-4 | 0.928 | |
unc-73 | Protein UNC-73 | 0.919 | |
hlh-1 | Protein HLH-1 | 0.915 | |
egl-18 | Protein EGL-18 | 0.886 | |
epi-1 | Protein EPI-1 | 0.780 | |
sem-5 | Protein SEM-5 | 0.745 | |
atn-1 | Protein ATN-1 | 0.736 | |
che-13 | Protein CHE-13 | 0.705 | |
egl-46 | Protein EGL-46 | 0.574 | |
egl-15 | Protein EGL-15 | 0.564 | |
unc-62 | Protein UNC-62 | 0.552 | |
egl-5 | Protein EGL-5 | 0.540 | |
wrm-1 | Protein WRM-1 | 0.462 | |
fkh-2 | Protein FKH-2 | 0.460 | |
unc-52 | Protein UNC-52 | 0.453 | |
vab-3 | Protein VAB-3 | 0.450 | |
hlh-2 | Protein HLH-2 | 0.436 | |
hbl-1 | Protein HBL-1 | 0.425 | |
lin-12 | Protein LIN-12 | 0.422 | |
ten-1 | Protein TEN-1 | 0.422 | |
ifb-2 | Protein IFB-2 | 0.418 | |
lin-17 | Protein LIN-17 | 0.394 | |
egl-44 | Protein EGL-44 | 0.378 | |
nhr-67 | Protein NHR-67 | 0.362 | |
pry-1 | Protein PRY-1 | 0.359 | |
ajm-1 | Protein AJM-1 | 0.354 | |
irx-1 | Protein IRX-1 | 0.349 | |
sel-12 | Protein SEL-12 | 0.344 | |
T28F4.1 | Protein T28F4.1 | 0.341 | |
osm-5 | Protein OSM-5 | 0.341 | |
rig-6 | Protein RIG-6 | 0.339 | |
egl-27 | Protein EGL-27 | 0.338 | |
bbs-1 | Protein BBS-1 | 0.330 | |
elt-6 | Protein ELT-6 | 0.328 | |
H43E16.1 | Protein H43E16.1 | 0.313 | |
bar-1 | Protein BAR-1 | 0.299 | |
eya-1 | Protein EYA-1 | 0.293 | |
myo-3 | Protein MYO-3 | 0.288 | |
ina-1 | Protein INA-1 | 0.287 | |
plc-1 | Protein PLC-1 | 0.283 | |
eat-6 | Protein EAT-6 | 0.282 | |
sax-7 | Protein SAX-7 | 0.273 | |
clh-5 | Protein CLH-5 | 0.264 | |
ain-1 | Protein AIN-1 | 0.259 | |
ifd-1 | Protein IFD-1 | 0.252 | |
lam-2 | Protein LAM-2 | 0.248 | |
lag-1 | Protein LAG-1 | 0.246 | |
dim-1 | Protein DIM-1 | 0.245 | |
trim-9 | Protein TRIM-9 | 0.239 | |
inx-5 | Protein INX-5 | 0.235 | |
apl-1 | Protein APL-1 | 0.229 | |
pac-1 | Protein PAC-1 | 0.227 | |
mig-6 | Protein MIG-6 | 0.226 | |
nhr-34 | Protein NHR-34 | 0.226 | |
aph-2 | Protein APH-2 | 0.223 | |
cam-1 | Protein CAM-1 | 0.220 | |
goa-1 | Protein GOA-1 | 0.218 | |
unc-98 | Protein UNC-98 | 0.218 | |
lin-29 | Protein LIN-29 | 0.215 | |
vbh-1 | Protein VBH-1 | 0.215 | |
mig-5 | Protein MIG-5 | 0.205 | |
unc-42 | Protein UNC-42 | 0.203 | |
mab-5 | Protein MAB-5 | 0.203 | |
spc-1 | Protein SPC-1 | 0.191 | |
emb-9 | Protein EMB-9 | 0.187 | |
nfi-1 | Protein NFI-1 | 0.186 | |
hmg-1.2 | Protein HMG-1.2 | 0.184 | |
aspm-1 | Protein ASPM-1 | 0.182 | |
sma-6 | Protein SMA-6 | 0.182 | |
attf-2 | Protein ATTF-2 | 0.180 | |
dre-1 | Protein DRE-1 | 0.180 | |
unc-130 | Protein UNC-130 | 0.177 | |
T21B6.3 | Protein T21B6.3 | 0.177 | |
gly-12 | Protein GLY-12 | 0.175 | |
sel-10 | Protein SEL-10 | 0.171 | |
cwn-1 | Protein CWN-1 | 0.171 | |
fasn-1 | Protein FASN-1 | 0.164 | |
unc-37 | Protein UNC-37 | 0.163 | |
abu-15 | Protein ABU-15 | 0.158 | |
imb-2 | Protein IMB-2 | 0.158 | |
T12D8.9 | Protein T12D8.9 | 0.158 | |
npp-1 | Protein NPP-1 | 0.157 | |
gon-4 | Protein GON-4 | 0.157 | |
tra-1 | Protein TRA-1 | 0.155 | |
CELE_F54D5.5 | Protein F54D5.5 | 0.154 | |
hrpf-2 | Protein HRPF-2 | 0.151 | |
nhr-25 | Protein NHR-25 | 0.151 | |
che-2 | Protein CHE-2 | 0.149 | |
ida-1 | Protein IDA-1 | 0.147 | |
tax-6 | Protein TAX-6 | 0.146 | |
B0336.3 | Protein B0336.3 | 0.145 | |
C53C9.2 | Protein C53C9.2 | 0.143 | |
gei-18 | Protein GEI-18 | 0.143 | |
pup-2 | Protein PUP-2 | 0.142 | |
T20F5.6 | Protein T20F5.6 | 0.141 | |
dnc-2 | Protein DNC-2 | 0.141 | |
lin-14 | Protein LIN-14 | 0.140 | |
nrde-3 | Protein NRDE-3 | 0.140 | |
unc-6 | Protein UNC-6 | 0.139 | |
emb-5 | Protein EMB-5 | 0.138 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Hoxb7 | homeo box B7 | 0.533 | |
Ankrd1 | ankyrin repeat domain 1 (cardiac muscle) | 0.507 | |
Col3a1 | collagen, type III, alpha 1 | 0.386 | |
Ednrb | endothelin receptor type B | 0.374 | |
Actc1 | actin, alpha, cardiac muscle 1 | 0.363 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.356 | |
Col1a1 | collagen, type I, alpha 1 | 0.314 | |
Mrgprf | MAS-related GPR, member F | 0.298 | |
Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.285 | |
Sirpa | signal-regulatory protein alpha | 0.283 | |
Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.280 | |
Igfbp5 | insulin-like growth factor binding protein 5 | 0.279 | |
Stat5b | signal transducer and activator of transcription 5B | 0.274 | |
Foxd3 | forkhead box D3 | 0.273 | |
Klk1l | kallikrein 1-like peptidase | 0.269 | |
Crisp1 | cysteine-rich secretory protein 1 | 0.257 | |
Hoxc4 | homeo box C4 | 0.253 | |
Myo1e | myosin IE | 0.253 | |
Col12a1 | collagen, type XII, alpha 1 | 0.246 | |
Prrx1 | paired related homeobox 1 | 0.245 | |
Vim | vimentin | 0.244 | |
Bgn | biglycan | 0.239 | |
Dbh | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 0.237 | |
Bmp6 | bone morphogenetic protein 6 | 0.233 | |
Grk1 | G protein-coupled receptor kinase 1 | 0.231 | |
Tacr1 | tachykinin receptor 1 | 0.229 | |
Eln | elastin | 0.222 | |
Sod3 | superoxide dismutase 3, extracellular | 0.222 | |
Mybpc1 | myosin binding protein C, slow type | 0.221 | |
Gna12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.213 | |
Ireb2 | iron responsive element binding protein 2 | 0.212 | |
Pla1a | phospholipase A1 member A | 0.209 | |
Atp2b3 | ATPase, Ca++ transporting, plasma membrane 3 | 0.205 | |
Krt5 | keratin 5 | 0.195 | |
Tnni3 | troponin I type 3 (cardiac) | 0.194 | |
Gata3 | GATA binding protein 3 | 0.194 | |
Amelx | amelogenin X chromosome | 0.193 | |
Efna5 | ephrin A5 | 0.190 | |
Fbln5 | fibulin 5 | 0.188 | |
Myh3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.187 | |
Vcan | versican | 0.181 | |
Fn1 | fibronectin 1 | 0.180 | |
Klf13 | Kruppel-like factor 13 | 0.175 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.175 | |
Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.170 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.167 | |
Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.165 | |
Shox2 | short stature homeobox 2 | 0.164 | |
Smad7 | SMAD family member 7 | 0.163 | |
Robo1 | roundabout homolog 1 (Drosophila) | 0.160 | |
Dchs1 | dachsous 1 (Drosophila) | 0.159 | |
Opn1sw | opsin 1 (cone pigments), short-wave-sensitive | 0.158 | |
Lepr | leptin receptor | 0.156 | |
Krt14 | keratin 14 | 0.153 | |
Col5a2 | collagen, type V, alpha 2 | 0.153 | |
Reg3a | regenerating islet-derived 3 alpha | 0.152 | |
Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform | 0.152 | |
Sorbs1 | sorbin and SH3 domain containing 1 | 0.152 | |
Atp1a1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.152 | |
Rara | retinoic acid receptor, alpha | 0.151 | |
Col1a2 | collagen, type I, alpha 2 | 0.149 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.149 | |
Nrl | neural retina leucine zipper | 0.149 | |
Vat1 | vesicle amine transport protein 1 homolog (T californica) | 0.149 | |
Fat2 | FAT tumor suppressor homolog 2 (Drosophila) | 0.146 | |
Ets1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.145 | |
Mpp3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | 0.144 | |
Lyve1 | lymphatic vessel endothelial hyaluronan receptor 1 | 0.140 | |
Capn6 | calpain 6 | 0.136 | |
Pla2g5 | phospholipase A2, group V | 0.135 | |
Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.134 | |
Fgd4 | FYVE, RhoGEF and PH domain containing 4 | 0.133 | |
Sdc3 | syndecan 3 | 0.133 | |
Lox | lysyl oxidase | 0.132 | |
Adam17 | ADAM metallopeptidase domain 17 | 0.132 | |
Krt15 | keratin 15 | 0.131 | |
Dab2 | disabled homolog 2 (Drosophila) | 0.131 | |
Prl3a1 | Prolactin family 3, subfamily a, member 1 | 0.131 | |
Nrg1 | neuregulin 1 | 0.131 | |
Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.127 | |
Oxtr | oxytocin receptor | 0.127 | |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.126 | |
Npr3 | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 0.126 | |
Galr3 | galanin receptor 3 | 0.125 | |
Lig3 | ligase III, DNA, ATP-dependent | 0.124 | |
Reln | reelin | 0.124 | |
Plod2 | procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.122 | |
Irx4 | iroquois homeobox 4 | 0.120 | |
Ednra | endothelin receptor type A | 0.119 | |
Id3 | inhibitor of DNA binding 3 | 0.119 | |
Bmp3 | bone morphogenetic protein 3 | 0.118 | |
Dlx5 | distal-less homeobox 5 | 0.117 | |
Cnga4 | cyclic nucleotide gated channel alpha 4 | 0.117 | |
Cd40lg | CD40 ligand | 0.116 | |
Ahr | aryl hydrocarbon receptor | 0.116 | |
Loxl1 | lysyl oxidase-like 1 | 0.116 | |
Psgb1 | pregnancy-specific beta 1-glycoprotein | 0.114 | |
Ager | advanced glycosylation end product-specific receptor | 0.111 | |
Dctn4 | dynactin 4 | 0.111 | |
Gata6 | GATA binding protein 6 | 0.111 |