The network for 'organ morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
ESR1 estrogen receptor 1 1.000
TP53 tumor protein p53 1.000
YAP1 Yes-associated protein 1 0.999
FLNA filamin A, alpha 0.999
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.999
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.999
FN1 fibronectin 1 0.998
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.998
SP1 Sp1 transcription factor 0.997
CDK2 cyclin-dependent kinase 2 0.997
CREBBP CREB binding protein 0.997
NCOR1 nuclear receptor corepressor 1 0.996
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.994
FGFR2 fibroblast growth factor receptor 2 0.994
SMAD2 SMAD family member 2 0.994
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.993
SFN stratifin 0.992
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.991
HDAC1 histone deacetylase 1 0.990
MYOD1 myogenic differentiation 1 0.987
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.986
CAV1 caveolin 1, caveolae protein, 22kDa 0.986
RUNX1 runt-related transcription factor 1 0.984
TAL1 T-cell acute lymphocytic leukemia 1 0.979
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.976
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.976
MYH9 myosin, heavy chain 9, non-muscle 0.975
THBS1 thrombospondin 1 0.972
CTGF connective tissue growth factor 0.972
NOTCH1 notch 1 0.971
PDX1 pancreatic and duodenal homeobox 1 0.966
JAG1 jagged 1 0.966
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.964
HDAC2 histone deacetylase 2 0.962
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.962
COL1A1 collagen, type I, alpha 1 0.957
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.955
TIMP3 TIMP metallopeptidase inhibitor 3 0.953
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.952
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.949
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.946
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.943
YY1 YY1 transcription factor 0.942
TP63 tumor protein p63 0.941
SMAD7 SMAD family member 7 0.940
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.935
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.935
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.933
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.930
RB1 retinoblastoma 1 0.925
FGF1 fibroblast growth factor 1 (acidic) 0.924
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.918
TCF4 transcription factor 4 0.917
SMAD4 SMAD family member 4 0.915
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.913
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.909
AR androgen receptor 0.908
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.905
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.901
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.897
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.894
FGFR1 fibroblast growth factor receptor 1 0.893
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.891
GATA4 GATA binding protein 4 0.891
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.889
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.884
HOXB5 homeobox B5 0.883
POU3F2 POU class 3 homeobox 2 0.882
CDK6 cyclin-dependent kinase 6 0.881
RBBP4 retinoblastoma binding protein 4 0.880
VEGFA vascular endothelial growth factor A 0.876
KLK10 kallikrein-related peptidase 10 0.870
EPAS1 endothelial PAS domain protein 1 0.868
NOTCH3 notch 3 0.868
GRB7 growth factor receptor-bound protein 7 0.868
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.867
PPARA peroxisome proliferator-activated receptor alpha 0.864
CCND1 cyclin D1 0.862
COL1A2 collagen, type I, alpha 2 0.851
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.848
NRP1 neuropilin 1 0.848
TP73 tumor protein p73 0.847
FHL2 four and a half LIM domains 2 0.847
FOXA2 forkhead box A2 0.841
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.840
PAX7 paired box 7 0.837
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.832
CDX2 caudal type homeobox 2 0.831
SCHIP1 schwannomin interacting protein 1 0.829
BCOR BCL6 corepressor 0.828
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.828
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.827
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.825
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.824
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
pha-4 Protein PHA-4 0.928
unc-73 Protein UNC-73 0.919
hlh-1 Protein HLH-1 0.915
egl-18 Protein EGL-18 0.886
epi-1 Protein EPI-1 0.780
sem-5 Protein SEM-5 0.745
atn-1 Protein ATN-1 0.736
che-13 Protein CHE-13 0.705
egl-46 Protein EGL-46 0.574
egl-15 Protein EGL-15 0.564
unc-62 Protein UNC-62 0.552
egl-5 Protein EGL-5 0.540
wrm-1 Protein WRM-1 0.462
fkh-2 Protein FKH-2 0.460
unc-52 Protein UNC-52 0.453
vab-3 Protein VAB-3 0.450
hlh-2 Protein HLH-2 0.436
hbl-1 Protein HBL-1 0.425
lin-12 Protein LIN-12 0.422
ten-1 Protein TEN-1 0.422
ifb-2 Protein IFB-2 0.418
lin-17 Protein LIN-17 0.394
egl-44 Protein EGL-44 0.378
nhr-67 Protein NHR-67 0.362
pry-1 Protein PRY-1 0.359
ajm-1 Protein AJM-1 0.354
irx-1 Protein IRX-1 0.349
sel-12 Protein SEL-12 0.344
T28F4.1 Protein T28F4.1 0.341
osm-5 Protein OSM-5 0.341
rig-6 Protein RIG-6 0.339
egl-27 Protein EGL-27 0.338
bbs-1 Protein BBS-1 0.330
elt-6 Protein ELT-6 0.328
H43E16.1 Protein H43E16.1 0.313
bar-1 Protein BAR-1 0.299
eya-1 Protein EYA-1 0.293
myo-3 Protein MYO-3 0.288
ina-1 Protein INA-1 0.287
plc-1 Protein PLC-1 0.283
eat-6 Protein EAT-6 0.282
sax-7 Protein SAX-7 0.273
clh-5 Protein CLH-5 0.264
ain-1 Protein AIN-1 0.259
ifd-1 Protein IFD-1 0.252
lam-2 Protein LAM-2 0.248
lag-1 Protein LAG-1 0.246
dim-1 Protein DIM-1 0.245
trim-9 Protein TRIM-9 0.239
inx-5 Protein INX-5 0.235
apl-1 Protein APL-1 0.229
pac-1 Protein PAC-1 0.227
mig-6 Protein MIG-6 0.226
nhr-34 Protein NHR-34 0.226
aph-2 Protein APH-2 0.223
cam-1 Protein CAM-1 0.220
goa-1 Protein GOA-1 0.218
unc-98 Protein UNC-98 0.218
lin-29 Protein LIN-29 0.215
vbh-1 Protein VBH-1 0.215
mig-5 Protein MIG-5 0.205
unc-42 Protein UNC-42 0.203
mab-5 Protein MAB-5 0.203
spc-1 Protein SPC-1 0.191
emb-9 Protein EMB-9 0.187
nfi-1 Protein NFI-1 0.186
hmg-1.2 Protein HMG-1.2 0.184
aspm-1 Protein ASPM-1 0.182
sma-6 Protein SMA-6 0.182
attf-2 Protein ATTF-2 0.180
dre-1 Protein DRE-1 0.180
unc-130 Protein UNC-130 0.177
T21B6.3 Protein T21B6.3 0.177
gly-12 Protein GLY-12 0.175
sel-10 Protein SEL-10 0.171
cwn-1 Protein CWN-1 0.171
fasn-1 Protein FASN-1 0.164
unc-37 Protein UNC-37 0.163
abu-15 Protein ABU-15 0.158
imb-2 Protein IMB-2 0.158
T12D8.9 Protein T12D8.9 0.158
npp-1 Protein NPP-1 0.157
gon-4 Protein GON-4 0.157
tra-1 Protein TRA-1 0.155
CELE_F54D5.5 Protein F54D5.5 0.154
hrpf-2 Protein HRPF-2 0.151
nhr-25 Protein NHR-25 0.151
che-2 Protein CHE-2 0.149
ida-1 Protein IDA-1 0.147
tax-6 Protein TAX-6 0.146
B0336.3 Protein B0336.3 0.145
C53C9.2 Protein C53C9.2 0.143
gei-18 Protein GEI-18 0.143
pup-2 Protein PUP-2 0.142
T20F5.6 Protein T20F5.6 0.141
dnc-2 Protein DNC-2 0.141
lin-14 Protein LIN-14 0.140
nrde-3 Protein NRDE-3 0.140
unc-6 Protein UNC-6 0.139
emb-5 Protein EMB-5 0.138
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hoxb7 homeo box B7 0.533
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.507
Col3a1 collagen, type III, alpha 1 0.386
Ednrb endothelin receptor type B 0.374
Actc1 actin, alpha, cardiac muscle 1 0.363
Fgfr2 fibroblast growth factor receptor 2 0.356
Col1a1 collagen, type I, alpha 1 0.314
Mrgprf MAS-related GPR, member F 0.298
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.285
Sirpa signal-regulatory protein alpha 0.283
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.280
Igfbp5 insulin-like growth factor binding protein 5 0.279
Stat5b signal transducer and activator of transcription 5B 0.274
Foxd3 forkhead box D3 0.273
Klk1l kallikrein 1-like peptidase 0.269
Crisp1 cysteine-rich secretory protein 1 0.257
Hoxc4 homeo box C4 0.253
Myo1e myosin IE 0.253
Col12a1 collagen, type XII, alpha 1 0.246
Prrx1 paired related homeobox 1 0.245
Vim vimentin 0.244
Bgn biglycan 0.239
Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.237
Bmp6 bone morphogenetic protein 6 0.233
Grk1 G protein-coupled receptor kinase 1 0.231
Tacr1 tachykinin receptor 1 0.229
Eln elastin 0.222
Sod3 superoxide dismutase 3, extracellular 0.222
Mybpc1 myosin binding protein C, slow type 0.221
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.213
Ireb2 iron responsive element binding protein 2 0.212
Pla1a phospholipase A1 member A 0.209
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.205
Krt5 keratin 5 0.195
Tnni3 troponin I type 3 (cardiac) 0.194
Gata3 GATA binding protein 3 0.194
Amelx amelogenin X chromosome 0.193
Efna5 ephrin A5 0.190
Fbln5 fibulin 5 0.188
Myh3 myosin, heavy chain 3, skeletal muscle, embryonic 0.187
Vcan versican 0.181
Fn1 fibronectin 1 0.180
Klf13 Kruppel-like factor 13 0.175
Tgfbr2 transforming growth factor, beta receptor II 0.175
Trpv1 transient receptor potential cation channel, subfamily V, member 1 0.170
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.167
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.165
Shox2 short stature homeobox 2 0.164
Smad7 SMAD family member 7 0.163
Robo1 roundabout homolog 1 (Drosophila) 0.160
Dchs1 dachsous 1 (Drosophila) 0.159
Opn1sw opsin 1 (cone pigments), short-wave-sensitive 0.158
Lepr leptin receptor 0.156
Krt14 keratin 14 0.153
Col5a2 collagen, type V, alpha 2 0.153
Reg3a regenerating islet-derived 3 alpha 0.152
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.152
Sorbs1 sorbin and SH3 domain containing 1 0.152
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.152
Rara retinoic acid receptor, alpha 0.151
Col1a2 collagen, type I, alpha 2 0.149
Ptprc protein tyrosine phosphatase, receptor type, C 0.149
Nrl neural retina leucine zipper 0.149
Vat1 vesicle amine transport protein 1 homolog (T californica) 0.149
Fat2 FAT tumor suppressor homolog 2 (Drosophila) 0.146
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.145
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.144
Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 0.140
Capn6 calpain 6 0.136
Pla2g5 phospholipase A2, group V 0.135
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.134
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.133
Sdc3 syndecan 3 0.133
Lox lysyl oxidase 0.132
Adam17 ADAM metallopeptidase domain 17 0.132
Krt15 keratin 15 0.131
Dab2 disabled homolog 2 (Drosophila) 0.131
Prl3a1 Prolactin family 3, subfamily a, member 1 0.131
Nrg1 neuregulin 1 0.131
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.127
Oxtr oxytocin receptor 0.127
Ptgs2 prostaglandin-endoperoxide synthase 2 0.126
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.126
Galr3 galanin receptor 3 0.125
Lig3 ligase III, DNA, ATP-dependent 0.124
Reln reelin 0.124
Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 0.122
Irx4 iroquois homeobox 4 0.120
Ednra endothelin receptor type A 0.119
Id3 inhibitor of DNA binding 3 0.119
Bmp3 bone morphogenetic protein 3 0.118
Dlx5 distal-less homeobox 5 0.117
Cnga4 cyclic nucleotide gated channel alpha 4 0.117
Cd40lg CD40 ligand 0.116
Ahr aryl hydrocarbon receptor 0.116
Loxl1 lysyl oxidase-like 1 0.116
Psgb1 pregnancy-specific beta 1-glycoprotein 0.114
Ager advanced glycosylation end product-specific receptor 0.111
Dctn4 dynactin 4 0.111
Gata6 GATA binding protein 6 0.111
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism