The network for 'innate immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

Mus musculus
Name Description Probability Func Analog Organism
Stat1 signal transducer and activator of transcription 1 0.997
Irf9 interferon regulatory factor 9 0.988
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.982
Myd88 myeloid differentiation primary response gene 88 0.978
Ccr2 chemokine (C-C motif) receptor 2 0.974
Lyz2 lysozyme 2 0.973
Trim21 tripartite motif-containing 21 0.971
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.970
Irf7 interferon regulatory factor 7 0.967
Ctnnb1 catenin (cadherin associated protein), beta 1 0.962
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.958
Gbp2 guanylate binding protein 2 0.958
Mapk14 mitogen-activated protein kinase 14 0.956
Tlr4 toll-like receptor 4 0.956
Igtp interferon gamma induced GTPase 0.953
Gbp7 guanylate binding protein 7 0.952
Cd180 CD180 antigen 0.950
Gbp3 guanylate binding protein 3 0.949
Ccl2 chemokine (C-C motif) ligand 2 0.944
H2-DMb2 histocompatibility 2, class II, locus Mb2 0.934
Tgfbr2 transforming growth factor, beta receptor II 0.929
Cd40 CD40 antigen 0.927
H2-Eb1 histocompatibility 2, class II antigen E beta 0.923
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.917
Irf1 interferon regulatory factor 1 0.910
Irgm2 immunity-related GTPase family M member 2 0.904
Uba7 ubiquitin-like modifier activating enzyme 7 0.897
Iigp1 interferon inducible GTPase 1 0.892
H2-Aa histocompatibility 2, class II antigen A, alpha 0.891
Csf1 colony stimulating factor 1 (macrophage) 0.886
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.881
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.875
Stat3 signal transducer and activator of transcription 3 0.872
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.869
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.865
Ciita class II transactivator 0.862
Ikbkg inhibitor of kappaB kinase gamma 0.860
H2-K1 histocompatibility 2, K1, K region 0.856
Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) 0.856
Ifitm3 interferon induced transmembrane protein 3 0.855
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.850
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.842
Irgm1 immunity-related GTPase family M member 1 0.841
Icos inducible T-cell co-stimulator 0.839
Parp14 poly (ADP-ribose) polymerase family, member 14 0.836
Il6 interleukin 6 0.833
Cxcl10 chemokine (C-X-C motif) ligand 10 0.824
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.824
Tnf tumor necrosis factor 0.817
Ncoa3 nuclear receptor coactivator 3 0.816
Ccl5 chemokine (C-C motif) ligand 5 0.802
Rac1 RAS-related C3 botulinum substrate 1 0.801
Tapbp TAP binding protein 0.789
Bcl3 B-cell leukemia/lymphoma 3 0.787
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.784
Nf1 neurofibromatosis 1 0.783
Ifng interferon gamma 0.782
Cd19 CD19 antigen 0.780
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.770
Socs1 suppressor of cytokine signaling 1 0.765
Casp1 caspase 1 0.763
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.757
AW112010 expressed sequence AW112010 0.751
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.745
Oasl2 2'-5' oligoadenylate synthetase-like 2 0.744
Efnb2 ephrin B2 0.743
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.739
Ikbkb inhibitor of kappaB kinase beta 0.739
H2-Q7 histocompatibility 2, Q region locus 7 0.736
Xcl1 chemokine (C motif) ligand 1 0.735
Birc3 baculoviral IAP repeat-containing 3 0.732
Usp18 ubiquitin specific peptidase 18 0.721
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.714
Cxcl9 chemokine (C-X-C motif) ligand 9 0.714
Gzma granzyme A 0.711
Slamf1 signaling lymphocytic activation molecule family member 1 0.708
Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 0.707
Ifi44 interferon-induced protein 44 0.704
Il1rn interleukin 1 receptor antagonist 0.704
H2-Q6 histocompatibility 2, Q region locus 6 0.702
Axl AXL receptor tyrosine kinase 0.701
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.696
Il2rg interleukin 2 receptor, gamma chain 0.694
Inpp5d inositol polyphosphate-5-phosphatase D 0.694
Parp9 poly (ADP-ribose) polymerase family, member 9 0.675
Ifi47 interferon gamma inducible protein 47 0.674
Itga4 integrin alpha 4 0.670
H2-D1 histocompatibility 2, D region locus 1 0.669
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.661
Ifih1 interferon induced with helicase C domain 1 0.659
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.658
Itk IL2-inducible T-cell kinase 0.658
Ms4a4c membrane-spanning 4-domains, subfamily A, member 4C 0.656
Ncr1 natural cytotoxicity triggering receptor 1 0.656
Tlr2 toll-like receptor 2 0.654
Rtp4 receptor transporter protein 4 0.650
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.650
Sfpi1 SFFV proviral integration 1 0.646
Ccr9 chemokine (C-C motif) receptor 9 0.643
Ccl4 chemokine (C-C motif) ligand 4 0.637
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
dod-24 Protein DOD-24 0.995
C34H4.2 Protein C34H4.2 0.984
C18E9.9 Protein C18E9.9 0.981
lys-2 Protein LYS-2 0.979
CELE_C17H12.8 Protein C17H12.8 0.975
C34H4.1 Protein C34H4.1 0.955
F08G5.6 Protein F08G5.6 0.927
dod-17 Protein DOD-17 0.920
ugt-44 Protein UGT-44 0.893
lys-1 Protein LYS-1 0.891
hsp-17 Protein HSP-17 0.890
clec-67 Protein CLEC-67 0.890
CELE_F55G11.2 Protein F55G11.2 0.879
clec-265 Protein CLEC-265 0.877
T01D3.6 Protein T01D3.6 0.867
tag-244 Protein TAG-244 0.862
C29F3.7 Protein C29F3.7 0.855
tag-120 Protein TAG-120 0.847
T24C4.4 Protein T24C4.4 0.844
gst-7 Protein GST-7 0.843
CELE_K08D8.6 Protein K08D8.6 0.838
CELE_C32H11.4 Protein C32H11.4 0.828
CELE_K08D8.5 Protein K08D8.5 0.816
hpo-6 Protein HPO-6 0.816
T28D9.3 Protein T28D9.3 0.804
lys-3 Protein LYS-3 0.789
CELE_F55G11.8 Protein F55G11.8 0.788
T20D3.2 Protein T20D3.2 0.773
zip-5 Protein ZIP-5 0.762
gst-6 Protein GST-6 0.758
clec-66 Protein CLEC-66 0.751
his-5 Protein HIS-5 0.737
CELE_Y40D12A.2 Protein Y40D12A.2 0.725
T19D12.4 Protein T19D12.4 0.715
C49C8.5 Protein C49C8.5 0.702
dod-22 Protein DOD-22 0.697
cpr-1 Protein CPR-1 0.696
clc-1 Protein CLC-1 0.695
CELE_F55G11.4 Protein F55G11.4 0.692
cyp-35C1 Protein CYP-35C1 0.691
gst-22 Protein GST-22 0.681
CELE_F53C11.1 Protein F53C11.1 0.672
F09A5.4 Protein F09A5.4 0.669
K06G5.1 Protein K06G5.1 0.667
cpr-3 Protein CPR-3 0.666
CELE_F35E12.5 Protein F35E12.5 0.664
CELE_F53B2.8 Protein F53B2.8 0.663
lec-10 Protein LEC-10 0.657
cdr-4 Protein CDR-4 0.649
ttm-5 Protein TTM-5 0.647
dod-19 Protein DOD-19 0.631
col-157 Protein COL-157 0.630
asp-6 Protein ASP-6 0.621
his-39 Protein HIS-39 0.615
his-4 Protein HIS-4 0.615
sqt-1 Protein SQT-1 0.613
CELE_F19B2.5 Protein F19B2.5 0.612
ncs-2 Protein NCS-2 0.610
CELE_C29F7.2 Protein C29F7.2 0.606
lys-8 Protein LYS-8 0.602
sek-1 Protein SEK-1 0.592
C18H9.6 Protein C18H9.6 0.591
his-16 Protein HIS-16 0.587
CELE_F35E12.8 Protein F35E12.8 0.582
gst-4 Protein GST-4 0.580
his-52 Protein HIS-52 0.580
clec-41 Protein CLEC-41 0.578
CELE_ZK1320.3 Protein ZK1320.3 0.577
zip-2 Protein ZIP-2 0.567
C16B8.3 Protein C16B8.3 0.567
F53A9.1 Protein F53A9.1 0.566
dpy-4 Protein DPY-4 0.565
clec-83 Protein CLEC-83 0.562
col-17 Protein COL-17 0.541
col-92 Protein COL-92 0.540
K11H12.4 Protein K11H12.4 0.532
Y37D8A.16 Protein Y37D8A.16 0.529
his-3 Protein HIS-3 0.528
F58A6.1 Protein F58A6.1 0.525
CELE_F35E12.6 Protein F35E12.6 0.524
CELE_F49F1.6 Protein F49F1.6 0.522
ugt-1 Protein UGT-1 0.521
acbp-3 Protein ACBP-3 0.518
W01A11.1 Protein W01A11.1 0.503
F46G10.1 Protein F46G10.1 0.501
CELE_K09D9.1 Protein K09D9.1 0.495
CELE_C17H12.6 Protein C17H12.6 0.488
ugt-22 Protein UGT-22 0.486
CELE_F54D5.4 Protein F54D5.4 0.484
CELE_F01D5.1 Protein F01D5.1 0.480
F54E2.1 Protein F54E2.1 0.479
rol-6 Protein ROL-6 0.476
Y77E11A.2 Protein Y77E11A.2 0.472
col-119 Protein COL-119 0.470
CELE_Y41D4B.17 Protein Y41D4B.17 0.466
C35B1.5 Protein C35B1.5 0.464
col-43 Protein COL-43 0.464
ZK970.7 Protein ZK970.7 0.460
col-140 Protein COL-140 0.457
C16D9.4 Protein C16D9.4 0.455
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cdh1 cadherin 1, epithelial 0.444
notch3 notch homolog 3 0.308
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.242
ptgds prostaglandin D2 synthase 0.225
ef1a elongation factor 1-alpha 0.200
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.199
nanos3 nanos homolog 3 0.196
irf11 interferon regulatory factor 11 0.185
LOC100151531 zinc finger protein Gfi-1b-like 0.184
pcsk2 proprotein convertase subtilisin/kexin type 2 0.159
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.155
apob apolipoprotein B 0.150
nod1 nucleotide-binding oligomerization domain containing 1 0.145
pcsk1 proprotein convertase subtilisin/kexin type 1 0.134
mmp9 matrix metalloproteinase 9 0.128
cyt1 type I cytokeratin, enveloping layer 0.125
coro1a coronin, actin binding protein, 1A 0.118
aldob aldolase b, fructose-bisphosphate 0.116
cd63 Cd63 antigen 0.114
foxi3a forkhead box I3a 0.113
tlr21 toll-like receptor 21 0.111
tlr3 toll-like receptor 3 0.102
rarga retinoic acid receptor gamma a 0.098
tlr9 toll-like receptor 9 0.093
vasa vasa homolog 0.093
pycard PYD and CARD domain containing 0.092
caspa caspase a 0.090
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.087
stat5.1 signal transducer and activator of transcription 5.1 0.085
itm2bb integral membrane protein 2Bb 0.084
foxa1 forkhead box A1 0.084
atf3 activating transcription factor 3 0.082
pcsk7 proprotein convertase subtilisin/kexin type 7 0.081
pcsk9 proprotein convertase subtilisin/kexin type 9 0.079
nfe2 nuclear factor, erythroid-derived 2 0.074
cdx1b caudal type homeobox 1 b 0.071
sox7 SRY-box containing gene 7 0.071
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.067
furinb furin (paired basic amino acid cleaving enzyme) b 0.064
upp2 uridine phosphorylase 2 0.064
ptgs1 prostaglandin-endoperoxide synthase 1 0.064
comta catechol-O-methyltransferase a 0.063
adra2b adrenergic, alpha-2B-, receptor 0.063
kdrl kinase insert domain receptor like 0.062
tnfb tumor necrosis factor b (TNF superfamily, member 2) 0.062
sult3st1 sulfotransferase family 3, cytosolic sulfotransferase 1 0.061
LOC557072 caspase recruitment domain-containing protein 11-like 0.060
plagl2 pleiomorphic adenoma gene-like 2 0.058
cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 0.058
cbr1l carbonyl reductase 1-like 0.057
nos2a nitric oxide synthase 2a, inducible 0.057
efnb3b ephrin B3b 0.056
boc brother of CDO 0.056
stat3 signal transduction and activation of transcription 3 0.055
b2m beta-2-microglobulin 0.055
keap1a kelch-like ECH-associated protein 1a 0.054
mat2a methionine adenosyltransferase II, alpha 0.054
eif3hb eukaryotic translation initiation factor 3, subunit H, b 0.052
rhogb ras homolog gene family, member Gb 0.051
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.051
c1qc complement component 1, q subcomponent, C chain 0.049
sgpp1 sphingosine-1-phosphate phosphatase 1 0.049
hdr hematopoietic death receptor 0.049
adra2a adrenergic, alpha-2A-, receptor 0.048
sh3gl1b SH3-domain GRB2-like 1b 0.048
psme1 proteasome activator subunit 1 0.047
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.046
nr2f5 nuclear receptor subfamily 2, group F, member 5 0.046
lpp LIM domain containing preferred translocation partner in lipoma 0.046
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.046
fgfr3 fibroblast growth factor receptor 3 0.045
six1b sine oculis homeobox homolog 1b 0.045
tie1 endothelium-specific receptor tyrosine kinase 1 0.044
smad1 MAD homolog 1 (Drosophila) 0.044
sp2 sp2 transcription factor 0.042
lipc lipase, hepatic 0.042
shbg sex hormone binding globulin 0.042
sfrp5 secreted frizzled-related protein 5 0.042
itln3 intelectin 3 0.041
pknox1.2 pbx/knotted 1 homeobox 1.2 0.041
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.041
irak4 interleukin-1 receptor-associated kinase 4 0.041
il6st interleukin 6 signal transducer 0.041
LOC100000934 hypothetical protein LOC100000934 0.040
tlr4bb toll-like receptor 4b, duplicate b 0.040
cldn2 claudin 2 0.040
hpx hemopexin 0.039
cldng claudin g 0.039
copb2 coatomer protein complex, subunit beta 2 0.039
tgfb3 transforming growth factor, beta 3 0.039
mitfa microphthalmia-associated transcription factor a 0.039
mmp14a matrix metalloproteinase 14a (membrane-inserted) 0.038
ncor1 nuclear receptor co-repressor 1 0.038
mapk3 mitogen-activated protein kinase 3 0.038
tal1 T-cell acute lymphocytic leukemia 1 0.037
hspa5 heat shock protein 5 0.037
si:ch211-212m21.5 si:ch211-212m21.5 0.036
mga MAX gene associated 0.035
yars tyrosyl-tRNA synthetase 0.035
wasa Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a 0.035
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
PGRP-LC Peptidoglycan recognition protein LC 1.000
Rel Relish 0.992
AttA Attacin-A 0.987
Spn27A Serpin 27A 0.973
fon fondue 0.968
spz spatzle 0.963
Jon99Ciii Jonah 99Ciii 0.937
p38b CG7393 gene product from transcript CG7393-RA 0.915
DptB Diptericin B 0.910
PGRP-SA Peptidoglycan recognition protein SA 0.904
AGO2 Argonaute 2 0.872
Dcr-2 Dicer-2 0.868
CG18594 CG18594 gene product from transcript CG18594-RA 0.868
Akt1 CG4006 gene product from transcript CG4006-RA 0.868
grass Gram-positive Specific Serine protease 0.867
Sp7 Serine protease 7 0.862
Dredd Death related ced-3/Nedd2-like protein 0.848
CG6361 CG6361 gene product from transcript CG6361-RA 0.846
BG4 CG12297 gene product from transcript CG12297-RA 0.791
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.790
Dhc64C Dynein heavy chain 64C 0.787
proPO-A1 prophenol oxidase A1 0.784
Lcp3 Larval cuticle protein 3 0.734
IM18 Immune induced molecule 18 0.730
Flo-2 flotillin 2 0.674
Lsp1alpha Larval serum protein 1 alpha 0.672
Spn1 Serine protease inhibitor 1 0.671
Mekk1 CG7717 gene product from transcript CG7717-RB 0.661
Irc Immune-regulated catalase 0.661
yip7 yippee interacting protein 7 0.644
imd immune deficiency 0.640
put punt 0.635
GNBP3 Gram-negative bacteria binding protein 3 0.631
alphaTry alphaTrypsin 0.626
lic licorne 0.626
Mtk Metchnikowin 0.623
Nrx-IV Neurexin IV 0.619
Jon65Ai Jonah 65Ai 0.612
Ras85D Ras oncogene at 85D 0.605
pzg putzig 0.596
Glt Glutactin 0.596
CG32185 CG32185 gene product from transcript CG32185-RA 0.594
CG8193 CG8193 gene product from transcript CG8193-RA 0.586
CG15917 CG15917 gene product from transcript CG15917-RA 0.584
SPE Spatzle-Processing Enzyme 0.582
Rac2 CG8556 gene product from transcript CG8556-RA 0.581
eater CG6124 gene product from transcript CG6124-RB 0.573
Spn28D Serpin 28D 0.571
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.560
Duox Dual oxidase 0.548
Pli Pellino 0.545
Lis-1 Lissencephaly-1 0.545
dia diaphanous 0.541
Tl Toll 0.533
Mpk2 CG5475 gene product from transcript CG5475-RB 0.515
CG6295 CG6295 gene product from transcript CG6295-RA 0.512
stck steamer duck 0.510
l(3)mbn lethal (3) malignant blood neoplasm 0.498
Myd88 CG2078 gene product from transcript CG2078-RA 0.489
CG10472 CG10472 gene product from transcript CG10472-RA 0.480
pie pineapple eye 0.452
PGRP-LF Peptidoglycan recognition protein LF 0.452
krz kurtz 0.443
AttC Attacin-C 0.432
betaTry betaTrypsin 0.412
dome domeless 0.411
CHORD CG6198 gene product from transcript CG6198-RA 0.402
CG5794 CG5794 gene product from transcript CG5794-RB 0.400
Exn Ephexin 0.399
Drs Drosomycin 0.390
Rac1 CG2248 gene product from transcript CG2248-RA 0.382
modSP modular serine protease 0.379
Cdc42 CG12530 gene product from transcript CG12530-RA 0.378
Hml Hemolectin 0.376
Mcr Macroglobulin complement-related 0.375
Atg1 Autophagy-specific gene 1 0.360
cact cactus 0.359
epsilonTry epsilonTrypsin 0.355
Mad Mothers against dpp 0.353
LysE Lysozyme E 0.345
Cpr49Ae Cuticular protein 49Ae 0.338
CG17633 CG17633 gene product from transcript CG17633-RA 0.338
Lcp2 Larval cuticle protein 2 0.336
ird1 immune response deficient 1 0.332
Pvf2 PDGF- and VEGF-related factor 2 0.330
CG16718 CG16718 gene product from transcript CG16718-RA 0.325
Krn Keren 0.324
GNBP1 Gram-negative bacteria binding protein 1 0.322
Adh Alcohol dehydrogenase 0.317
mael maelstrom 0.314
Top2 Topoisomerase 2 0.312
PGRP-LB Peptidoglycan recognition protein LB 0.311
vav CG7893 gene product from transcript CG7893-RB 0.310
Parp Poly-(ADP-ribose) polymerase 0.310
pnt pointed 0.309
LysD Lysozyme D 0.308
p53 CG33336 gene product from transcript CG33336-RB 0.305
CG15515 CG15515 gene product from transcript CG15515-RA 0.296
Nipped-A CG33554 gene product from transcript CG33554-RE 0.294
TM9SF4 CG7364 gene product from transcript CG7364-RA 0.289
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.000
MYD88 myeloid differentiation primary response gene (88) 0.999
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.999
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.997
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.990
TRAF6 TNF receptor-associated factor 6 0.990
RIPK2 receptor-interacting serine-threonine kinase 2 0.984
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.981
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.980
IRAK1 interleukin-1 receptor-associated kinase 1 0.978
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.977
UBC ubiquitin C 0.967
BIRC3 baculoviral IAP repeat containing 3 0.965
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.965
SP110 SP110 nuclear body protein 0.958
IFI44 interferon-induced protein 44 0.956
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.954
IFIH1 interferon induced with helicase C domain 1 0.945
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.944
B2M beta-2-microglobulin 0.943
NCF1 neutrophil cytosolic factor 1 0.937
BIRC2 baculoviral IAP repeat containing 2 0.935
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.935
MAPK14 mitogen-activated protein kinase 14 0.932
IRF9 interferon regulatory factor 9 0.928
EGFR epidermal growth factor receptor 0.917
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.915
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.914
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.914
HLA-C major histocompatibility complex, class I, C 0.900
LAT linker for activation of T cells 0.899
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.896
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.890
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.889
HIST1H2BD histone cluster 1, H2bd 0.884
JAK2 Janus kinase 2 0.884
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.872
SMN1 survival of motor neuron 1, telomeric 0.870
RXRA retinoid X receptor, alpha 0.869
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.865
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.850
ARRB1 arrestin, beta 1 0.844
CXCL10 chemokine (C-X-C motif) ligand 10 0.837
CHUK conserved helix-loop-helix ubiquitous kinase 0.835
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.832
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.829
HIST1H2BF histone cluster 1, H2bf 0.825
HIST1H2BE histone cluster 1, H2be 0.818
HLA-B major histocompatibility complex, class I, B 0.812
HLA-A major histocompatibility complex, class I, A 0.809
STAT1 signal transducer and activator of transcription 1, 91kDa 0.802
GBP1 guanylate binding protein 1, interferon-inducible 0.800
XIAP X-linked inhibitor of apoptosis 0.798
CCR1 chemokine (C-C motif) receptor 1 0.793
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.785
IRAK2 interleukin-1 receptor-associated kinase 2 0.774
FYN FYN oncogene related to SRC, FGR, YES 0.772
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.766
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.766
FAS Fas (TNF receptor superfamily, member 6) 0.758
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.753
FGA fibrinogen alpha chain 0.742
PYCARD PYD and CARD domain containing 0.734
C1S complement component 1, s subcomponent 0.733
APOE apolipoprotein E 0.727
HLA-E major histocompatibility complex, class I, E 0.724
IFI44L interferon-induced protein 44-like 0.721
MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 0.712
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.708
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.700
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.700
NMI N-myc (and STAT) interactor 0.694
GRB7 growth factor receptor-bound protein 7 0.691
ICAM1 intercellular adhesion molecule 1 0.684
SH2D1A SH2 domain containing 1A 0.672
KRT15 keratin 15 0.661
S100A8 S100 calcium binding protein A8 0.657
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.656
SQSTM1 sequestosome 1 0.650
MED10 mediator complex subunit 10 0.648
CXCL9 chemokine (C-X-C motif) ligand 9 0.645
MAPK1 mitogen-activated protein kinase 1 0.638
BTK Bruton agammaglobulinemia tyrosine kinase 0.638
SIGLEC7 sialic acid binding Ig-like lectin 7 0.635
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.635
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.632
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.631
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.624
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.622
TLR2 toll-like receptor 2 0.614
TRIM21 tripartite motif containing 21 0.613
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.611
CD163 CD163 molecule 0.607
HIST1H2BH histone cluster 1, H2bh 0.599
OASL 2'-5'-oligoadenylate synthetase-like 0.593
GHR growth hormone receptor 0.580
CCR5 chemokine (C-C motif) receptor 5 0.574
FGL2 fibrinogen-like 2 0.573
MAP2K4 mitogen-activated protein kinase kinase 4 0.568
SYK spleen tyrosine kinase 0.564
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Ba RT1 class II, locus Ba 0.752
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.599
Il1b interleukin 1 beta 0.548
RT1-DMb RT1 class II, locus DMb 0.530
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 0.482
Mmp12 matrix metallopeptidase 12 0.479
Cxcl10 chemokine (C-X-C motif) ligand 10 0.467
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.432
RT1-Da RT1 class II, locus Da 0.429
Ccl4 chemokine (C-C motif) ligand 4 0.397
Cd37 CD37 molecule 0.383
Ifitm3 interferon induced transmembrane protein 3 0.349
Xcl1 chemokine (C motif) ligand 1 0.337
Cfb complement factor B 0.291
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.286
RT1-EC2 RT1 class Ib, locus EC2 0.261
Cp ceruloplasmin 0.211
Hck hemopoietic cell kinase 0.206
B2m beta-2 microglobulin 0.189
C1s complement component 1, s subcomponent 0.181
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.170
Cd14 CD14 molecule 0.169
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.155
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.153
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.148
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.141
Casp1 caspase 1 0.136
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.134
Cxcl3 chemokine (C-X-C motif) ligand 3 0.132
Kynu kynureninase (L-kynurenine hydrolase) 0.130
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.126
Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 0.126
Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 0.124
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.123
Cd2 Cd2 molecule 0.123
Gckr glucokinase (hexokinase 4) regulator 0.122
Dnase1l3 deoxyribonuclease 1-like 3 0.122
Il6 interleukin 6 0.120
Neurl3 neuralized homolog 3 (Drosophila) 0.114
Ccr5 chemokine (C-C motif) receptor 5 0.103
Il2rb interleukin 2 receptor, beta 0.103
Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.101
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.100
Pax8 paired box 8 0.095
Scaf1 SR-related CTD-associated factor 1 0.094
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.091
Lcn2 lipocalin 2 0.091
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.089
Sell selectin L 0.088
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.088
Ncr1 natural cytotoxicity triggering receptor 1 0.087
Prf1 perforin 1 (pore forming protein) 0.086
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.086
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.085
Gfi1 growth factor independent 1 transcription repressor 0.085
Ptbp1 polypyrimidine tract binding protein 1 0.085
Il7r interleukin 7 receptor 0.084
Iapp islet amyloid polypeptide 0.083
Aqp9 aquaporin 9 0.083
Casp12 caspase 12 0.083
Csf1 colony stimulating factor 1 (macrophage) 0.082
Ifng interferon gamma 0.082
Gimap4 GTPase, IMAP family member 4 0.081
Arf6 ADP-ribosylation factor 6 0.081
Irf1 interferon regulatory factor 1 0.081
Eif4h eukaryotic translation initiation factor 4H 0.081
Rgs1 regulator of G-protein signaling 1 0.080
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.080
Apol3 apolipoprotein L, 3 0.079
Gbp2 guanylate binding protein 2 0.079
Stat3 signal transducer and activator of transcription 3 0.079
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.079
Scarb1 scavenger receptor class B, member 1 0.077
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.076
Edn1 endothelin 1 0.076
Nkg7 natural killer cell group 7 sequence 0.076
LOC100363783 rCG53773-like 0.076
Notch2 Notch homolog 2 (Drosophila) 0.073
RT1-Db1 RT1 class II, locus Db1 0.073
Oas1i 2 ' -5 ' oligoadenylate synthetase 1I 0.071
Gzmm granzyme M (lymphocyte met-ase 1) 0.069
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.069
Ahsg alpha-2-HS-glycoprotein 0.069
Lig3 ligase III, DNA, ATP-dependent 0.068
C7 complement component 7 0.067
Igsf6 immunoglobulin superfamily, member 6 0.067
Cxcl9 chemokine (C-X-C motif) ligand 9 0.067
Asgr2 asialoglycoprotein receptor 2 0.066
Icam1 intercellular adhesion molecule 1 0.066
C1r complement component 1, r subcomponent 0.066
Adora3 adenosine A3 receptor 0.066
Tchh trichohyalin 0.065
RGD1564599 RGD1564599 0.063
Hpgds hematopoietic prostaglandin D synthase 0.063
Cpb1 carboxypeptidase B1 (tissue) 0.063
Vav1 vav 1 guanine nucleotide exchange factor 0.063
Phkg1 phosphorylase kinase, gamma 1 0.061
Ifitm1 interferon induced transmembrane protein 1 0.061
Il8rb interleukin 8 receptor, beta 0.061
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.061
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism