The network for 'regulation of ion transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of ion transport

Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 1.000
Dlg4 discs, large homolog 4 (Drosophila) 0.998
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.979
Ryr2 ryanodine receptor 2, cardiac 0.978
Kl klotho 0.975
Vegfa vascular endothelial growth factor A 0.967
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.963
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.962
Scn5a sodium channel, voltage-gated, type V, alpha 0.962
Cd19 CD19 antigen 0.952
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.952
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.948
Pten phosphatase and tensin homolog 0.942
Drd2 dopamine receptor D2 0.939
Inpp5d inositol polyphosphate-5-phosphatase D 0.933
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.930
Tnf tumor necrosis factor 0.928
Nos1 nitric oxide synthase 1, neuronal 0.927
Gja1 gap junction protein, alpha 1 0.921
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.914
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.904
Bcl2 B-cell leukemia/lymphoma 2 0.903
Ldb3 LIM domain binding 3 0.901
Adra2c adrenergic receptor, alpha 2c 0.896
Grm1 glutamate receptor, metabotropic 1 0.881
Ank1 ankyrin 1, erythroid 0.878
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.874
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.870
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.842
Sult4a1 sulfotransferase family 4A, member 1 0.830
Igh immunoglobulin heavy chain complex 0.827
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.819
Ache acetylcholinesterase 0.818
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.818
Dtna dystrobrevin alpha 0.818
Kcnk3 potassium channel, subfamily K, member 3 0.814
Cckbr cholecystokinin B receptor 0.813
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.810
Lrp1 low density lipoprotein receptor-related protein 1 0.809
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.803
Emx1 empty spiracles homolog 1 (Drosophila) 0.788
Nos3 nitric oxide synthase 3, endothelial cell 0.788
Grb2 growth factor receptor bound protein 2 0.785
Neurod2 neurogenic differentiation 2 0.781
Homer1 homer homolog 1 (Drosophila) 0.772
Lepr leptin receptor 0.770
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.769
Prkce protein kinase C, epsilon 0.761
Clock circadian locomotor output cycles kaput 0.754
Kcna6 potassium voltage-gated channel, shaker-related, subfamily, member 6 0.739
Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 0.738
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.737
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.733
Smyd1 SET and MYND domain containing 1 0.732
Rnf112 ring finger protein 112 0.730
Hrh1 histamine receptor H1 0.727
Hif1a hypoxia inducible factor 1, alpha subunit 0.717
Atoh7 atonal homolog 7 (Drosophila) 0.705
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.702
Ltb lymphotoxin B 0.701
Lhx3 LIM homeobox protein 3 0.700
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.700
Cbl Casitas B-lineage lymphoma 0.693
Grb10 growth factor receptor bound protein 10 0.693
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.691
Pcsk2 proprotein convertase subtilisin/kexin type 2 0.685
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.685
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 0.680
B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 0.673
Skil SKI-like 0.666
Actn2 actinin alpha 2 0.666
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.666
Was Wiskott-Aldrich syndrome homolog (human) 0.665
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.658
Oprm1 opioid receptor, mu 1 0.658
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.654
Pvalb parvalbumin 0.654
Egfr epidermal growth factor receptor 0.652
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.641
Adam11 a disintegrin and metallopeptidase domain 11 0.641
Shh sonic hedgehog 0.640
Ccr1 chemokine (C-C motif) receptor 1 0.635
Sstr4 somatostatin receptor 4 0.633
Srpk3 serine/arginine-rich protein specific kinase 3 0.631
Cd28 CD28 antigen 0.627
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.625
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.619
Nos2 nitric oxide synthase 2, inducible 0.618
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.616
Fgf13 fibroblast growth factor 13 0.611
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.610
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.609
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.607
Dnm1 dynamin 1 0.606
Pthlh parathyroid hormone-like peptide 0.601
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.598
Il6 interleukin 6 0.595
Syn2 synapsin II 0.595
Scn7a sodium channel, voltage-gated, type VII, alpha 0.594
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.594
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pkg-1 Protein PKG-1 0.484
unc-36 Protein UNC-36 0.385
spc-1 Protein SPC-1 0.285
unc-9 Protein UNC-9 0.256
nlg-1 Protein NLG-1 0.251
eat-4 Protein EAT-4 0.229
vav-1 Protein VAV-1 0.182
itr-1 Protein ITR-1 0.179
gar-3 Protein GAR-3 0.136
dpy-23 Protein DPY-23 0.132
eat-6 Protein EAT-6 0.128
unc-115 Protein UNC-115 0.120
dyc-1 Protein DYC-1 0.109
eps-8 Protein EPS-8 0.107
F39G3.5 Protein F39G3.5 0.103
ist-1 Protein IST-1 0.096
insc-1 Protein INSC-1 0.083
unc-7 Protein UNC-7 0.081
sym-4 Protein SYM-4 0.081
K10D6.2 Protein K10D6.2 0.081
vab-3 Protein VAB-3 0.073
inx-4 Protein INX-4 0.073
egl-8 Protein EGL-8 0.072
pes-7 Protein PES-7 0.072
ger-1 Protein GER-1 0.070
inx-12 Protein INX-12 0.070
lim-9 Protein LIM-9 0.066
gpb-1 Protein GPB-1 0.062
R11G1.6 Protein R11G1.6 0.062
pkn-1 Protein PKN-1 0.061
inx-1 Protein INX-1 0.058
efn-2 Protein EFN-2 0.058
F49E2.5 Protein F49E2.5 0.056
plc-1 Protein PLC-1 0.055
R90.1 Protein R90.1 0.053
egl-19 Protein EGL-19 0.052
tax-6 Protein TAX-6 0.050
ifd-1 Protein IFD-1 0.049
F32B5.7 Protein F32B5.7 0.048
madd-4 Protein MADD-4 0.046
ncs-2 Protein NCS-2 0.046
cah-2 Protein CAH-2 0.045
sma-6 Protein SMA-6 0.044
C24A3.2 Protein C24A3.2 0.043
sdha-1 Protein SDHA-1 0.042
vha-13 Protein VHA-13 0.042
srv-1 Protein SRV-1 0.041
ace-1 Protein ACE-1 0.041
T28B4.1 Protein T28B4.1 0.040
ajm-1 Protein AJM-1 0.040
slo-1 Protein SLO-1 0.040
dys-1 Protein DYS-1 0.040
csnk-1 Protein CSNK-1 0.039
F28E10.1 Protein F28E10.1 0.039
plc-3 Protein PLC-3 0.039
sli-1 Protein SLI-1 0.038
slt-1 Protein SLT-1 0.038
nhr-31 Protein NHR-31 0.038
CELE_F59C6.11 Protein F59C6.11 0.037
syg-1 Protein SYG-1 0.037
CELE_F17C11.12 Protein F17C11.12 0.036
CELE_W05H12.1 Protein W05H12.1 0.036
sol-1 Protein SOL-1 0.036
sup-12 Protein SUP-12 0.036
feh-1 Protein FEH-1 0.034
unc-83 Protein UNC-83 0.034
prl-1 Protein PRL-1 0.034
gcy-28 Protein GCY-28 0.034
twk-18 Protein TWK-18 0.034
ncr-1 Protein NCR-1 0.033
C06E4.2 Protein C06E4.2 0.033
vha-16 Protein VHA-16 0.033
Y71H10A.1 Protein Y71H10A.1 0.033
nrx-1 Protein NRX-1 0.033
lec-1 Protein LEC-1 0.032
rig-3 Protein RIG-3 0.032
F54E4.3 Protein F54E4.3 0.031
aak-2 Protein AAK-2 0.031
T05G5.1 Protein T05G5.1 0.031
CELE_C56A3.6 Protein C56A3.6 0.031
cmd-1 Protein CMD-1 0.031
mod-1 Protein MOD-1 0.031
CELE_Y37A1B.17 Protein Y37A1B.17 0.031
ZC449.5 Protein ZC449.5 0.031
tmc-2 Protein TMC-2 0.031
egl-13 Protein EGL-13 0.031
F49E10.4 Protein F49E10.4 0.030
mec-18 Protein MEC-18 0.029
mltn-1 Protein MLTN-1 0.029
glr-5 Protein GLR-5 0.028
B0507.1 Protein B0507.1 0.028
bar-1 Protein BAR-1 0.028
ipp-5 Protein IPP-5 0.028
sax-7 Protein SAX-7 0.028
T25C12.3 Protein T25C12.3 0.028
egl-15 Protein EGL-15 0.027
rgs-2 Protein RGS-2 0.027
mec-2 Protein MEC-2 0.027
adt-2 Protein ADT-2 0.027
stim-1 Protein STIM-1 0.026
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cldni claudin i 0.504
cldnb claudin b 0.396
scn12ab sodium channel, voltage gated, type XII, alpha b 0.379
gfra1a gdnf family receptor alpha 1a 0.316
ptmaa prothymosin, alpha a 0.266
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.265
osr2 odd-skipped related 2 (Drosophila) 0.233
gpia glucose phosphate isomerase a 0.231
gja3 gap junction protein, alpha 3 0.222
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.222
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.211
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.208
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.199
cdh23 cadherin-like 23 0.169
fgf20a fibroblast growth factor 20a 0.158
scn1ba sodium channel, voltage-gated, type I, beta a 0.154
cpla2 cytosolic phospholipase a2 0.142
cldnh claudin h 0.134
ndrg4 N-myc downstream regulated gene 4 0.126
nlgn2b neuroligin 2b 0.112
sh3gl1b SH3-domain GRB2-like 1b 0.101
aldh1a3 aldehyde dehydrogenase 1 family, member A3 0.097
kitb kit receptor b 0.094
kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.089
dpysl5b dihydropyrimidinase-like 5b 0.087
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.087
cdh17 cadherin 17, LI cadherin (liver-intestine) 0.087
cntn1a contactin 1a 0.087
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.087
cdh1 cadherin 1, epithelial 0.081
epcam epithelial cell adhesion molecule 0.081
drd2b dopamine receptor D2b 0.081
hspa5 heat shock protein 5 0.081
cldn2 claudin 2 0.080
tnnc1b troponin C type 1b (slow) 0.072
atp2b1a ATPase, Ca++ transporting, plasma membrane 1a 0.071
olig1 oligodendrocyte lineage transcription factor 1 0.070
hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.068
hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.068
nlgn2a neuroligin 2a 0.068
il6st interleukin 6 signal transducer 0.067
slc4a4a solute carrier family 4, member 4a 0.067
efna5b ephrin A5b 0.066
cntn2 contactin 2 0.064
hspb1 heat shock protein, alpha-crystallin-related, 1 0.063
mapk1 mitogen-activated protein kinase 1 0.063
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.062
slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.061
inha inhibin, alpha 0.060
ryr1b ryanodine receptor 1b (skeletal) 0.059
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.058
cyfip2 cytoplasmic FMR1 interacting protein 2 0.058
il6r interleukin 6 receptor 0.058
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.058
rag1 recombination activating gene 1 0.058
chrm2a cholinergic receptor, muscarinic 2a 0.057
cx55.5 connexin 55.5 0.057
prkcq protein kinase C, theta 0.056
gpr126 G protein-coupled receptor 126 0.056
plp1b proteolipid protein 1b 0.055
zp2.2 zona pellucida glycoprotein 2.2 0.055
igfbp3 insulin-like growth factor binding protein 3 0.055
eya4 eyes absent homolog 4 (Drosophila) 0.053
prkcz protein kinase C, zeta 0.052
s1pr2 sphingosine-1-phosphate receptor 2 0.051
scn12aa sodium channel, voltage gated, type XII, alpha a 0.051
penka proenkephalin a 0.050
si:dkeyp-51c11.1 si:dkeyp-51c11.1 0.049
ckbb creatine kinase, brain b 0.049
bdnf brain-derived neurotrophic factor 0.047
cx39.9 connexin 39.9 0.047
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.046
nlgn1 neuroligin 1 0.046
flj13639 flj13639 0.045
scn4ba sodium channel, voltage-gated, type IV, beta a 0.045
dlg2 discs, large (Drosophila) homolog 2 0.044
hmx2 H6 family homeobox 2 0.044
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.043
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.040
osr1 odd-skipped related 1 (Drosophila) 0.040
pvalb8 parvalbumin 8 0.040
runx1 runt-related transcription factor 1 0.040
hpca hippocalcin 0.040
mef2ca myocyte enhancer factor 2ca 0.039
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.039
tsc22d3 TSC22 domain family, member 3 0.039
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.039
ntrk3b neurotrophic tyrosine kinase, receptor, type 3b 0.038
cyp1b1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.037
hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.037
rspo1 R-spondin homolog (Xenopus laevis) 0.037
scn8ab sodium channel, voltage-gated, type VIII, alpha b 0.036
psen1 presenilin 1 0.036
stc1l stanniocalcin 1, like 0.036
tnnt2a troponin T2a, cardiac 0.036
agr2 anterior gradient homolog 2 (Xenopus laevis) 0.035
bik BCL2-interacting killer (apoptosis-inducing) 0.035
zgc:56382 zgc:56382 0.034
fabp7a fatty acid binding protein 7, brain, a 0.034
tnnc2 troponin C type 2 (fast) 0.034
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
bsk basket 0.482
cac cacophony 0.386
TER94 CG2331 gene product from transcript CG2331-RA 0.375
rut rutabaga 0.364
Alk CG8250 gene product from transcript CG8250-RA 0.351
Nrg Neuroglian 0.349
amon amontillado 0.346
Ca-P60A Calcium ATPase at 60A 0.321
Dcr-2 Dicer-2 0.320
fng fringe 0.293
ClC-b Chloride channel-b 0.267
nwk nervous wreck 0.266
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.242
dnc dunce 0.240
S6k RPS6-p70-protein kinase 0.225
Sara Smad anchor for receptor activation 0.216
CG32635 CG32635 gene product from transcript CG32635-RA 0.210
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.193
norpA no receptor potential A 0.187
Ork1 Open rectifier K[+] channel 1 0.165
Tbh Tyramine beta hydroxylase 0.156
Rdl Resistant to dieldrin 0.151
Ace Acetylcholine esterase 0.145
CG34400 CG34400 gene product from transcript CG34400-RD 0.137
comt comatose 0.134
Sema-1a CG18405 gene product from transcript CG18405-RD 0.129
mbc myoblast city 0.126
CdsA CDP diglyceride synthetase 0.124
Stam Signal transducing adaptor molecule 0.109
fd85E forkhead domain 85E 0.107
Irk3 Inwardly rectifying potassium channel 3 0.103
Tak1 TGF-beta activated kinase 1 0.098
plx pollux 0.094
Pkn Protein kinase related to protein kinase N 0.094
tws twins 0.085
egh egghead 0.084
G-oalpha47A G protein oalpha 47A 0.082
Amph Amphiphysin 0.079
para paralytic 0.077
Nmdar2 NMDA receptor 2 0.076
Syx1A Syntaxin 1A 0.076
Atpalpha Na pump alpha subunit 0.073
tai taiman 0.070
CG42629 CG42629 gene product from transcript CG42629-RB 0.070
nudE CG8104 gene product from transcript CG8104-RB 0.069
dos daughter of sevenless 0.069
inaD inactivation no afterpotential D 0.068
CG11448 CG11448 gene product from transcript CG11448-RA 0.068
Gad1 Glutamic acid decarboxylase 1 0.066
usp ultraspiracle 0.066
RanBPM Ran-binding protein M 0.065
Dab Disabled 0.064
trp transient receptor potential 0.064
Rac1 CG2248 gene product from transcript CG2248-RA 0.063
rdgC retinal degeneration C 0.061
Fas2 Fasciclin 2 0.059
egr eiger 0.058
gfA giant fibre A 0.056
Nrx-1 Neurexin 1 0.056
baz bazooka 0.054
CkIalpha Casein kinase Ialpha 0.054
GluRIIA Glutamate receptor IIA 0.054
Rh6 Rhodopsin 6 0.053
ST6Gal Sialyltransferase 0.052
Ca-beta Ca2+-channel-protein-beta-subunit 0.051
Mpk2 CG5475 gene product from transcript CG5475-RB 0.050
Galpha49B G protein alpha49B 0.049
Dad Daughters against dpp 0.047
5-HT7 Serotonin receptor 7 0.045
Fatp Fatty acid (long chain) transport protein 0.045
Hk Hyperkinetic 0.045
Sdc Syndecan 0.044
Actn alpha actinin 0.042
Hnf4 Hepatocyte nuclear factor 4 0.041
wit wishful thinking 0.040
nAcRalpha-7E nicotinic Acetylcholine Receptor alpha 7E 0.040
wgn wengen 0.039
Gr43a Gustatory receptor 43a 0.039
Snap25 Synapse protein 25 0.039
CG13253 CG13253 gene product from transcript CG13253-RB 0.039
Mad Mothers against dpp 0.038
ppk11 pickpocket 11 0.038
Pgk Phosphoglycerate kinase 0.037
Adar Adenosine deaminase acting on RNA 0.037
VAChT CG32848 gene product from transcript CG32848-RA 0.037
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.037
Clk Clock 0.037
CG42542 CG42542 gene product from transcript CG42542-RE 0.037
spas spastin 0.036
dhd deadhead 0.036
Nmdar1 NMDA receptor 1 0.036
Cat Catalase 0.036
Traf6 TNF-receptor-associated factor 6 0.035
Ank2 Ankyrin 2 0.035
Stim Stromal interaction molecule 0.034
por porcupine 0.034
slo slowpoke 0.034
spz spatzle 0.034
CG34139 CG34139 gene product from transcript CG34139-RD 0.034
Vha26 Vacuolar H[+]-ATPase 26kD E subunit 0.033
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
DLG4 discs, large homolog 4 (Drosophila) 1.000
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.999
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.998
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.992
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.990
KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 0.985
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.982
CCR5 chemokine (C-C motif) receptor 5 0.977
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.975
IL8 interleukin 8 0.968
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.953
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.942
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.926
GSTM1 glutathione S-transferase mu 1 0.915
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.913
BCL2 B-cell CLL/lymphoma 2 0.897
ARRB1 arrestin, beta 1 0.894
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.887
TJP1 tight junction protein 1 (zona occludens 1) 0.880
SFN stratifin 0.880
LRRK2 leucine-rich repeat kinase 2 0.870
MAPT microtubule-associated protein tau 0.863
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.857
TBX5 T-box 5 0.850
GSTM2 glutathione S-transferase mu 2 (muscle) 0.831
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.829
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.825
APP amyloid beta (A4) precursor protein 0.824
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.821
PTPRN protein tyrosine phosphatase, receptor type, N 0.811
S100B S100 calcium binding protein B 0.794
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.794
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.765
CSK c-src tyrosine kinase 0.753
INSR insulin receptor 0.749
CABP1 calcium binding protein 1 0.745
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.743
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.739
CCKBR cholecystokinin B receptor 0.731
DMD dystrophin 0.727
GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) 0.727
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.703
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.700
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.699
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.698
GOPC golgi-associated PDZ and coiled-coil motif containing 0.693
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.691
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.685
CXCL3 chemokine (C-X-C motif) ligand 3 0.684
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.684
KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 0.679
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.678
CXCL9 chemokine (C-X-C motif) ligand 9 0.677
ACTL6B actin-like 6B 0.658
YAP1 Yes-associated protein 1 0.657
CXCL2 chemokine (C-X-C motif) ligand 2 0.654
ACTN2 actinin, alpha 2 0.650
BIRC3 baculoviral IAP repeat containing 3 0.647
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.645
KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 0.644
PLAU plasminogen activator, urokinase 0.639
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.638
CCL8 chemokine (C-C motif) ligand 8 0.637
CXCL5 chemokine (C-X-C motif) ligand 5 0.637
PRKCG protein kinase C, gamma 0.625
CCL7 chemokine (C-C motif) ligand 7 0.613
SPTB spectrin, beta, erythrocytic 0.612
THBS1 thrombospondin 1 0.608
BCL2L1 BCL2-like 1 0.606
HP haptoglobin 0.598
MPZL2 myelin protein zero-like 2 0.597
KCNJ9 potassium inwardly-rectifying channel, subfamily J, member 9 0.597
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.595
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.568
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A 0.562
ACHE acetylcholinesterase 0.561
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.557
A2M alpha-2-macroglobulin 0.556
BAD BCL2-associated agonist of cell death 0.550
FLNA filamin A, alpha 0.546
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.546
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.543
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.541
IFNG interferon, gamma 0.539
PDZK1 PDZ domain containing 1 0.538
GSK3B glycogen synthase kinase 3 beta 0.537
PRKCA protein kinase C, alpha 0.534
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.531
IL6 interleukin 6 (interferon, beta 2) 0.528
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.522
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.521
CCL20 chemokine (C-C motif) ligand 20 0.519
CCL5 chemokine (C-C motif) ligand 5 0.519
RYR2 ryanodine receptor 2 (cardiac) 0.513
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.511
CAB39 calcium binding protein 39 0.511
PTEN phosphatase and tensin homolog 0.510
SCN5A sodium channel, voltage-gated, type V, alpha subunit 0.508
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.497
CCL2 chemokine (C-C motif) ligand 2 0.495
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Grm7 glutamate receptor, metabotropic 7 0.927
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.923
Hrh3 histamine receptor H3 0.779
Ccl4 chemokine (C-C motif) ligand 4 0.714
Olr1082 olfactory receptor 1082 0.708
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.706
Spt1 salivary protein 1 0.685
Dlg4 discs, large homolog 4 (Drosophila) 0.682
Folh1 folate hydrolase 1 0.677
Oxtr oxytocin receptor 0.667
Sstr1 somatostatin receptor 1 0.658
Accn2 amiloride-sensitive cation channel 2, neuronal 0.646
Drd1a dopamine receptor D1A 0.638
Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 0.636
Mag myelin-associated glycoprotein 0.619
Hrh4 histamine receptor H4 0.617
Ncan neurocan 0.614
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.609
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.599
Gja1 gap junction protein, alpha 1 0.596
Neu2 sialidase 2 (cytosolic sialidase) 0.594
Adam2 ADAM metallopeptidase domain 2 0.594
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.590
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.575
LOC60591 calcium-activated potassium channel beta subunit 0.575
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.575
Pnlip pancreatic lipase 0.570
Aqp4 aquaporin 4 0.565
Inhba inhibin beta-A 0.559
P2rx6 purinergic receptor P2X, ligand-gated ion channel, 6 0.550
Gpr83 G protein-coupled receptor 83 0.548
Psp parotid secretory protein 0.541
Syt4 synaptotagmin IV 0.538
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.536
Mep1b meprin 1 beta 0.532
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.531
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.527
Myl7 myosin, light chain 7, regulatory 0.521
Neurl3 neuralized homolog 3 (Drosophila) 0.510
Grik1 glutamate receptor, ionotropic, kainate 1 0.510
Gfra2 GDNF family receptor alpha 2 0.506
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.502
Pde3a phosphodiesterase 3A, cGMP inhibited 0.491
Pdyn prodynorphin 0.491
Fgfr2 fibroblast growth factor receptor 2 0.490
Rims1 regulating synaptic membrane exocytosis 1 0.488
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.479
Cav1 caveolin 1, caveolae protein 0.478
Acr acrosin 0.469
Avpr1b arginine vasopressin receptor 1B 0.468
Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 0.464
Calcrl calcitonin receptor-like 0.463
Oprd1 opioid receptor, delta 1 0.461
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.458
Gucy2d guanylate cyclase 2d 0.452
Kl Klotho 0.450
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.447
Plcd4 phospholipase C, delta 4 0.446
Ccl20 chemokine (C-C motif) ligand 20 0.444
Oprk1 opioid receptor, kappa 1 0.435
Slc22a25 solute carrier family 22, member 25 0.435
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.434
Itgam integrin, alpha M 0.434
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.424
Ptafr platelet-activating factor receptor 0.422
Pftk1 PFTAIRE protein kinase 1 0.418
Epo erythropoietin 0.415
Crybb3 crystallin, beta B3 0.415
Tbxa2r thromboxane A2 receptor 0.405
Cnksr2 connector enhancer of kinase suppressor of Ras 2 0.405
Gzmk granzyme K 0.404
Ldb3 LIM domain binding 3 0.401
Grid2 glutamate receptor, ionotropic, delta 2 0.399
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.399
Cacng4 calcium channel, voltage-dependent, gamma subunit 4 0.398
P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.391
Kif6 kinesin family member 6 0.389
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.383
Nlrp6 NLR family, pyrin domain containing 6 0.381
Sstr5 somatostatin receptor 5 0.377
Strn striatin, calmodulin binding protein 0.376
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.376
Omp olfactory marker protein 0.375
Ccr3 chemokine (C-C motif) receptor 3 0.372
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.371
Pex5l peroxisomal biogenesis factor 5-like 0.371
Gfra1 GDNF family receptor alpha 1 0.369
Catsper2 cation channel, sperm associated 2 0.369
Kcnh5 potassium voltage-gated channel, subfamily H (eag-related), member 5 0.367
Ckm creatine kinase, muscle 0.366
Shank2 SH3 and multiple ankyrin repeat domains 2 0.365
Aqp6 aquaporin 6, kidney specific 0.364
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.363
Nrxn1 neurexin 1 0.362
Capn13 calpain 13 0.359
Tff1 trefoil factor 1 0.355
Sirpa signal-regulatory protein alpha 0.354
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.352
Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.351
Plin perilipin 0.350
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MOB1 Mob1p 0.082
AQY2 Aqy2p 0.075
APL3 Apl3p 0.066
MIG1 Mig1p 0.047
CRZ1 Crz1p 0.038
YPK1 Ypk1p 0.037
MLC1 Mlc1p 0.032
MDS3 Mds3p 0.031
PMR1 Pmr1p 0.026
PAM1 Pam1p 0.025
HOF1 Hof1p 0.023
MSN4 Msn4p 0.021
MGA2 Mga2p 0.021
SNF1 Snf1p 0.021
HAL5 Hal5p 0.020
URA2 Ura2p 0.019
RIM101 Rim101p 0.019
SMP1 Smp1p 0.019
TOR2 Tor2p 0.018
EAR1 Ear1p 0.018
SBH1 Sbh1p 0.018
GLN3 Gln3p 0.018
ACH1 Ach1p 0.018
RGD2 Rgd2p 0.017
HXT3 Hxt3p 0.017
BUD4 Bud4p 0.016
UBP9 Ubp9p 0.016
YPK2 Ypk2p 0.015
YAK1 Yak1p 0.015
GIP2 Gip2p 0.015
EHT1 Eht1p 0.015
SSK2 Ssk2p 0.015
NDE1 Nde1p 0.014
MBR1 Mbr1p 0.014
GPT2 Gpt2p 0.014
SKO1 Sko1p 0.014
YKR075C hypothetical protein 0.014
YTA6 Yta6p 0.014
CUE4 Cue4p 0.014
SAT4 Sat4p 0.014
GAT2 Gat2p 0.013
FPK1 Fpk1p 0.013
ZAP1 Zap1p 0.013
UPS3 Ups3p 0.013
TUB1 Tub1p 0.013
SWI5 Swi5p 0.013
NUP157 Nup157p 0.013
NEM1 Nem1p 0.013
TPO2 Tpo2p 0.013
HRK1 Hrk1p 0.013
PCL9 Pcl9p 0.013
RMA1 Rma1p 0.013
CBK1 Cbk1p 0.012
YPR157W hypothetical protein 0.012
MIR1 Mir1p 0.012
PRS2 Prs2p 0.012
MSN5 Msn5p 0.012
STE18 Ste18p 0.012
TRA1 Tra1p 0.012
AVT7 Avt7p 0.012
FKH1 Fkh1p 0.012
KEX1 Kex1p 0.012
GAL7 Gal7p 0.011
YPL014W hypothetical protein 0.011
YGR125W hypothetical protein 0.011
CCC1 Ccc1p 0.011
LEU5 Leu5p 0.011
YKL187C hypothetical protein 0.011
RGS2 Rgs2p 0.011
FKH2 Fkh2p 0.011
HOR2 Hor2p 0.011
DOT6 Dot6p 0.011
IES1 Ies1p 0.011
SEC4 Sec4p 0.011
STE5 Ste5p 0.011
YIP3 Yip3p 0.011
YLR297W hypothetical protein 0.011
MSG5 Msg5p 0.011
NUP1 Nup1p 0.011
ATG29 Atg29p 0.011
APM4 Apm4p 0.010
MNL1 Mnl1p 0.010
MCA1 Mca1p 0.010
ROX1 Rox1p 0.010
TOR1 Tor1p 0.010
GLT1 Glt1p 0.010
SPL2 Spl2p 0.010
YIR035C hypothetical protein 0.010