The network for 'regulation of t cell mediated immunity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of t cell mediated immunity

Any process that modulates the frequency, rate, or extent of T cell mediated immunity.

Mus musculus
Name Description Probability Func Analog Organism
B2m beta-2 microglobulin 0.988
H2-K1 histocompatibility 2, K1, K region 0.951
H2-D1 histocompatibility 2, D region locus 1 0.947
Cd40 CD40 antigen 0.883
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.845
H2-Q7 histocompatibility 2, Q region locus 7 0.821
Casp8 caspase 8 0.752
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.673
Lyz2 lysozyme 2 0.666
Clec4d C-type lectin domain family 4, member d 0.648
Tnf tumor necrosis factor 0.614
Pnp2 purine-nucleoside phosphorylase 2 0.576
Irf1 interferon regulatory factor 1 0.518
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.518
Fyn Fyn proto-oncogene 0.479
Tcra T-cell receptor alpha chain 0.462
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.429
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.427
Il1b interleukin 1 beta 0.378
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.376
Foxp3 forkhead box P3 0.374
Traf6 TNF receptor-associated factor 6 0.356
Ccl2 chemokine (C-C motif) ligand 2 0.353
Ccl8 chemokine (C-C motif) ligand 8 0.351
Ccl3 chemokine (C-C motif) ligand 3 0.351
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.328
Tapbp TAP binding protein 0.323
Cd209b CD209b antigen 0.312
Ccl4 chemokine (C-C motif) ligand 4 0.301
Ccr1 chemokine (C-C motif) receptor 1 0.300
Ccl22 chemokine (C-C motif) ligand 22 0.290
Mmp12 matrix metallopeptidase 12 0.275
Ubd ubiquitin D 0.243
H2-Aa histocompatibility 2, class II antigen A, alpha 0.213
Ccl5 chemokine (C-C motif) ligand 5 0.207
Itgb2 integrin beta 2 0.201
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.173
Clec4e C-type lectin domain family 4, member e 0.164
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.160
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.160
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.159
H2-Q6 histocompatibility 2, Q region locus 6 0.159
Birc3 baculoviral IAP repeat-containing 3 0.151
Itgax integrin alpha X 0.141
Cd28 CD28 antigen 0.137
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.137
Lck lymphocyte protein tyrosine kinase 0.136
Ccl6 chemokine (C-C motif) ligand 6 0.133
Cd247 CD247 antigen 0.126
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.125
Ccr7 chemokine (C-C motif) receptor 7 0.119
H2-Eb1 histocompatibility 2, class II antigen E beta 0.119
Ikzf1 IKAROS family zinc finger 1 0.116
Ifngr1 interferon gamma receptor 1 0.114
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.114
Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) 0.111
Lat linker for activation of T cells 0.105
Tspo2 translocator protein 2 0.102
Msr1 macrophage scavenger receptor 1 0.100
Cd209g CD209g antigen 0.098
Ccr2 chemokine (C-C motif) receptor 2 0.097
Il2rg interleukin 2 receptor, gamma chain 0.097
Cxcl2 chemokine (C-X-C motif) ligand 2 0.097
Ccl12 chemokine (C-C motif) ligand 12 0.095
Ccl7 chemokine (C-C motif) ligand 7 0.095
Il23a interleukin 23, alpha subunit p19 0.092
Cd4 CD4 antigen 0.091
Ciita class II transactivator 0.090
Il27ra interleukin 27 receptor, alpha 0.087
Cd209d CD209d antigen 0.086
Ikbkg inhibitor of kappaB kinase gamma 0.085
Casp1 caspase 1 0.085
Clec4n C-type lectin domain family 4, member n 0.084
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.084
Myd88 myeloid differentiation primary response gene 88 0.079
Gzma granzyme A 0.079
Folr2 folate receptor 2 (fetal) 0.078
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.077
Ccl9 chemokine (C-C motif) ligand 9 0.076
Selp selectin, platelet 0.075
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.075
Cd14 CD14 antigen 0.075
Cd44 CD44 antigen 0.073
Batf basic leucine zipper transcription factor, ATF-like 0.072
Il12b interleukin 12b 0.072
Cxcl16 chemokine (C-X-C motif) ligand 16 0.071
Fas Fas (TNF receptor superfamily member 6) 0.069
Pycard PYD and CARD domain containing 0.066
Tectb tectorin beta 0.065
H2-Q8 histocompatibility 2, Q region locus 8 0.065
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.064
Btk Bruton agammaglobulinemia tyrosine kinase 0.064
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.060
Map3k5 mitogen-activated protein kinase kinase kinase 5 0.058
Pik3cg phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.058
Fcna ficolin A 0.058
Irf7 interferon regulatory factor 7 0.056
Gdf15 growth differentiation factor 15 0.056
Cxcl10 chemokine (C-X-C motif) ligand 10 0.056
Havcr2 hepatitis A virus cellular receptor 2 0.055
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HLA-A major histocompatibility complex, class I, A 0.986
HLA-G major histocompatibility complex, class I, G 0.976
B2M beta-2-microglobulin 0.960
HLA-B major histocompatibility complex, class I, B 0.948
HLA-C major histocompatibility complex, class I, C 0.897
TRAF6 TNF receptor-associated factor 6 0.834
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.827
TRAF1 TNF receptor-associated factor 1 0.782
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.686
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.672
TAPBP TAP binding protein (tapasin) 0.658
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.636
BIRC3 baculoviral IAP repeat containing 3 0.406
CCL4 chemokine (C-C motif) ligand 4 0.392
HLA-E major histocompatibility complex, class I, E 0.327
CFLAR CASP8 and FADD-like apoptosis regulator 0.317
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.277
HLA-F major histocompatibility complex, class I, F 0.265
CCR5 chemokine (C-C motif) receptor 5 0.260
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.252
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.197
CD40 CD40 molecule, TNF receptor superfamily member 5 0.184
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.179
CCL5 chemokine (C-C motif) ligand 5 0.176
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.160
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.150
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.079
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.079
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.074
CXCL9 chemokine (C-X-C motif) ligand 9 0.071
CCL8 chemokine (C-C motif) ligand 8 0.062
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 0.060
CXCL11 chemokine (C-X-C motif) ligand 11 0.059
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.059
CCR7 chemokine (C-C motif) receptor 7 0.059
TNF tumor necrosis factor 0.058
CCL2 chemokine (C-C motif) ligand 2 0.057
OASL 2'-5'-oligoadenylate synthetase-like 0.051
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 0.048
PVRL4 poliovirus receptor-related 4 0.047
IL2RG interleukin 2 receptor, gamma 0.047
PILRA paired immunoglobin-like type 2 receptor alpha 0.044
CD163 CD163 molecule 0.041
VAMP4 vesicle-associated membrane protein 4 0.041
CCL13 chemokine (C-C motif) ligand 13 0.040
IL1B interleukin 1, beta 0.040
ZMYND11 zinc finger, MYND-type containing 11 0.037
CCR1 chemokine (C-C motif) receptor 1 0.037
IDE insulin-degrading enzyme 0.037
SIGLEC7 sialic acid binding Ig-like lectin 7 0.036
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.036
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.035
IL6 interleukin 6 (interferon, beta 2) 0.035
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.031
TGIF1 TGFB-induced factor homeobox 1 0.031
CALCOCO2 calcium binding and coiled-coil domain 2 0.030
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.030
CXCL13 chemokine (C-X-C motif) ligand 13 0.029
CD33 CD33 molecule 0.028
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.028
FASLG Fas ligand (TNF superfamily, member 6) 0.028
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.027
FAS Fas (TNF receptor superfamily, member 6) 0.027
BIRC2 baculoviral IAP repeat containing 2 0.027
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.026
SQSTM1 sequestosome 1 0.025
TRAF3 TNF receptor-associated factor 3 0.024
CCL7 chemokine (C-C motif) ligand 7 0.023
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.023
NUMBL numb homolog (Drosophila)-like 0.023
HK3 hexokinase 3 (white cell) 0.022
RIPK2 receptor-interacting serine-threonine kinase 2 0.022
PVRL3 poliovirus receptor-related 3 0.021
CD22 CD22 molecule 0.020
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.020
TRAF2 TNF receptor-associated factor 2 0.020
PTAFR platelet-activating factor receptor 0.019
IL10 interleukin 10 0.019
CD48 CD48 molecule 0.018
CCR4 chemokine (C-C motif) receptor 4 0.018
IFNG interferon, gamma 0.018
CCL19 chemokine (C-C motif) ligand 19 0.017
HSPH1 heat shock 105kDa/110kDa protein 1 0.017
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.017
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.016
IL10RA interleukin 10 receptor, alpha 0.016
IL2RB interleukin 2 receptor, beta 0.016
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.016
CCL22 chemokine (C-C motif) ligand 22 0.016
FPR3 formyl peptide receptor 3 0.015
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.015
TJP1 tight junction protein 1 (zona occludens 1) 0.015
CD80 CD80 molecule 0.015
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.014
CD86 CD86 molecule 0.014
SMAD3 SMAD family member 3 0.014
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.013
IL4R interleukin 4 receptor 0.013
NLRP3 NLR family, pyrin domain containing 3 0.013
CLEC10A C-type lectin domain family 10, member A 0.013
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hsph1 heat shock 105/110 protein 1 0.228
RT1-EC2 RT1 class Ib, locus EC2 0.064
Stip1 stress-induced phosphoprotein 1 0.017
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.013
RT1-CE12 RT1 class I, locus CE12 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism