IMP

Process View

Drosophila melanogaster

3 genes annotated in fly

substrate dependent cell migration

The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "substrate dependent cell migration"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "substrate dependent cell migration" (in gray)

Name	Description	Probability	Func Analog Organism
lea	leak	0.925	Human
sli	slit	0.921	Human
numb	CG3779 gene product from transcript CG3779-RB	0.874
robo	roundabout	0.703	Human
Abl	Abl tyrosine kinase	0.566	Mouse
bnl	branchless	0.424
zfh1	Zn finger homeodomain 1	0.413
ena	enabled	0.410
Ptp69D	Protein tyrosine phosphatase 69D	0.395	Human
comm	commissureless	0.390
cno	canoe	0.389
wb	wing blister	0.345
fra	frazzled	0.344
shg	shotgun	0.316
stumps	CG31317 gene product from transcript CG31317-RC	0.279
Rac1	CG2248 gene product from transcript CG2248-RA	0.268
baz	bazooka	0.257
trio	CG18214 gene product from transcript CG18214-RA	0.251
Hem	HEM-protein	0.213
gcm	glial cells missing	0.194
mys	myospheroid	0.190
mbc	myoblast city	0.185
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.178
aop	anterior open	0.176
Cdc42	CG12530 gene product from transcript CG12530-RA	0.170
sr	stripe	0.166
LanA	Laminin A	0.161
mam	mastermind	0.156
ed	echinoid	0.136
DAAM	Dishevelled Associated Activator of Morphogenesis	0.134
pyd	polychaetoid	0.132
flw	flapwing	0.130
neur	neuralized	0.129
CG5694	CG5694 gene product from transcript CG5694-RA	0.116
foi	fear-of-intimacy	0.115
jing	CG9397 gene product from transcript CG9397-RI	0.112
sim	single-minded	0.111
Wnt5	Wnt oncogene analog 5	0.109
crb	crumbs	0.087
Mrtf	Myocardin-related transcription factor	0.087
ptc	patched	0.082
Nrx-IV	Neurexin IV	0.081
scb	scab	0.080	Human Mouse
spi	spitz	0.077
sw	short wing	0.076
repo	reversed polarity	0.076
unc-5	CG8166 gene product from transcript CG8166-RA	0.074
par-1	CG8201 gene product from transcript CG8201-RA	0.073
rok	Rho-kinase	0.071
ush	u-shaped	0.070
rap	retina aberrant in pattern	0.069
CG9795	CG9795 gene product from transcript CG9795-RD	0.066
twi	twist	0.064
hts	hu li tai shao	0.064
babo	baboon	0.062
ttk	tramtrack	0.059
hyd	hyperplastic discs	0.059
arr	arrow	0.059
fas	faint sausage	0.058
lilli	lilliputian	0.058
if	inflated	0.057
retn	retained	0.056
plexB	plexin B	0.056
Tom	Twin of m4	0.055
rst	roughest	0.054
Lasp	CG3849 gene product from transcript CG3849-RB	0.053
ec	echinus	0.051
sdt	stardust	0.050
hbs	hibris	0.049
pnr	pannier	0.049
robo3	CG5423 gene product from transcript CG5423-RA	0.049	Human
tld	tolloid	0.045
lola	longitudinals lacking	0.045
dock	dreadlocks	0.044	Mouse
tgo	tango	0.044
plexA	plexin A	0.043
pod1	CG4532 gene product from transcript CG4532-RF	0.040
msn	misshapen	0.040
bsk	basket	0.040
rib	ribbon	0.039
hkb	huckebein	0.038
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.037
pnt	pointed	0.035
kuz	kuzbanian	0.034
capt	capulet	0.033
Ptp52F	CG18243 gene product from transcript CG18243-RB	0.033
Mical	Molecule interacting with CasL	0.033
mid	midline	0.032
Nrg	Neuroglian	0.032
tutl	turtle	0.032
Tsp96F	Tetraspanin 96F	0.031
scny	scrawny	0.030
htl	heartless	0.029	Rat
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.029
drk	downstream of receptor kinase	0.029
Cul-2	Cullin-2	0.028
esg	escargot	0.028	Mouse
shn	schnurri	0.027
ewg	erect wing	0.027
Dscam	Down syndrome cell adhesion molecule	0.027
mira	miranda	0.027
vvl	ventral veins lacking	0.026
os	outstretched	0.026
nvy	nervy	0.026
spdo	sanpodo	0.025
vnd	ventral nervous system defective	0.025
CG11376	CG11376 gene product from transcript CG11376-RA	0.025
Rho1	CG8416 gene product from transcript CG8416-RB	0.025
tkv	thickveins	0.024
Kr	Kruppel	0.024
insc	inscuteable	0.024
Gef26	CG9491 gene product from transcript CG9491-RB	0.024
tbce	tubulin-specific chaperone E	0.024
Sra-1	specifically Rac1-associated protein 1	0.023
noc	no ocelli	0.023
tai	taiman	0.023
NetB	Netrin-B	0.023
Hmgcr	HMG Coenzyme A reductase	0.022
hh	hedgehog	0.022
ems	empty spiracles	0.022
E(bx)	Enhancer of bithorax	0.021
Src64B	Src oncogene at 64B	0.021
Fak56D	Focal Adhesion Kinase	0.021
N	Notch	0.021
Ced-12	CG5336 gene product from transcript CG5336-RA	0.020
pxb	CG33207 gene product from transcript CG33207-RB	0.020
Fas3	Fasciclin 3	0.020
ab	abrupt	0.020
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.020
unk	unkempt	0.020
CadN	Cadherin-N	0.020
spin	spinster	0.020
slpr	slipper	0.019
Pvr	PDGF- and VEGF-receptor related	0.019
RhoGAP71E	CG32149 gene product from transcript CG32149-RD	0.019
kon	kon-tiki	0.019
Lim3	CG10699 gene product from transcript CG10699-RB	0.019
CG32016	CG32016 gene product from transcript CG32016-RB	0.018
sqz	squeeze	0.018
kkv	krotzkopf verkehrt	0.018
egh	egghead	0.018
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.018
bchs	blue cheese	0.018
Dad	Daughters against dpp	0.018
tll	tailless	0.018
nau	nautilus	0.018
svp	seven up	0.018
byn	brachyenteron	0.017
Six4	CG3871 gene product from transcript CG3871-RA	0.017
bru-3	bruno-3	0.017
CG9650	CG9650 gene product from transcript CG9650-RG	0.017
E(spl)	Enhancer of split	0.017
da	daughterless	0.017
rols	rolling pebbles	0.017
stan	starry night	0.016
salm	spalt major	0.016
Src42A	Src oncogene at 42A	0.016
Jra	Jun-related antigen	0.016
nerfin-1	nervous fingers 1	0.016
mmy	mummy	0.016
mew	multiple edematous wings	0.016
pcs	parcas	0.016
CG3563	CG3563 gene product from transcript CG3563-RA	0.016
CG10543	CG10543 gene product from transcript CG10543-RA	0.016
l(2)05510	lethal (2) 05510	0.016
dally	division abnormally delayed	0.015
sktl	skittles	0.015
Mef2	Myocyte enhancer factor 2	0.015
tup	tailup	0.015
ari-1	ariadne	0.015
Ptp10D	Protein tyrosine phosphatase 10D	0.015
Pvf1	PDGF- and VEGF-related factor 1	0.015	Mouse
fdl	fused lobes	0.015
gfA	giant fibre A	0.015
Pvf2	PDGF- and VEGF-related factor 2	0.015
sqh	spaghetti squash	0.015
NFAT	NFAT homolog	0.014
betaInt-nu	beta[nu] integrin	0.014
lt	light	0.014
lab	labial	0.014
cher	cheerio	0.014
CG12029	CG12029 gene product from transcript CG12029-RB	0.014
bur	burgundy	0.014
wor	worniu	0.014
exex	extra-extra	0.014
Trim9	CG31721 gene product from transcript CG31721-RB	0.013
eg	eagle	0.013
HLH54F	CG5005 gene product from transcript CG5005-RA	0.013
CG10984	CG10984 gene product from transcript CG10984-RC	0.013
Cul-3	Cullin-3	0.013
RN-tre	tre oncogene-related protein	0.013
Mhc	Myosin heavy chain	0.013
blow	blown fuse	0.013
ck	crinkled	0.013
par-6	CG5884 gene product from transcript CG5884-RA	0.013
cora	coracle	0.013
tsh	teashirt	0.013
stet	stem cell tumor	0.013
Smg5	CG8954 gene product from transcript CG8954-RA	0.013
Syx1A	Syntaxin 1A	0.013
trn	tartan	0.013
gfzf	GST-containing FLYWCH zinc-finger protein	0.013
ro	rough	0.013
CG8176	CG8176 gene product from transcript CG8176-RD	0.013
chb	chromosome bows	0.013
slbo	slow border cells	0.013
Galpha73B	G protein alpha 73B	0.013
nrm	neuromusculin	0.013
Btk29A	Btk family kinase at 29A	0.013
oaf	out at first	0.012
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.012
sls	sallimus	0.012
chic	chickadee	0.012
Pkn	Protein kinase related to protein kinase N	0.012
aux	auxillin	0.012
CG6051	CG6051 gene product from transcript CG6051-RB	0.012
pros	prospero	0.012
wls	wntless	0.012
Abi	Abelson interacting protein	0.012
ken	ken and barbie	0.011
btl	breathless	0.011	Rat
lmd	lame duck	0.011
l(2)k16918	lethal (2) k16918	0.011
Slip1	CG1783 gene product from transcript CG1783-RA	0.011
zpg	zero population growth	0.011
put	punt	0.011
Mtl	Mig-2-like	0.011
mol	moladietz	0.011
CG5727	CG5727 gene product from transcript CG5727-RA	0.011
cv-c	crossveinless c	0.011
Npc1b	Niemann-Pick type C-1b	0.011
RhoL	rho-like	0.011
mas	masquerade	0.011
wntD	wnt inhibitor of Dorsal	0.011
fs(1)h	female sterile (1) homeotic	0.011
Arf51F	ADP ribosylation factor 51F	0.011
eya	eyes absent	0.011
drl	derailed	0.010
hfw	halfway	0.010
CG2747	CG2747 gene product from transcript CG2747-RD	0.010
LIMK1	LIM-kinase1	0.010
Act5C	Actin 5C	0.010
4EHP	CG33100 gene product from transcript CG33100-RA	0.010
nimC3	nimrod C3	0.010
Wnt2	Wnt oncogene analog 2	0.010
drpr	draper	0.010