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Process View

Mus musculus

3 genes annotated in mouse

lateral mesoderm formation

The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lateral mesoderm formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lateral mesoderm formation" (in gray)

Name	Description	Probability	Func Analog Organism
Foxc1	forkhead box C1	0.999
Bmp4	bone morphogenetic protein 4	0.999
Shh	sonic hedgehog	0.996
Fgfr2	fibroblast growth factor receptor 2	0.996	Mouse
Sox9	SRY-box containing gene 9	0.995
Tgfbr2	transforming growth factor, beta receptor II	0.995	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.994
Tgfb2	transforming growth factor, beta 2	0.989
Gli3	GLI-Kruppel family member GLI3	0.984
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.973
Pax3	paired box gene 3	0.964
Apc	adenomatosis polyposis coli	0.959
Fgf8	fibroblast growth factor 8	0.931
Acvr1	activin A receptor, type 1	0.913	Mouse
Rarg	retinoic acid receptor, gamma	0.875
Fgfr1	fibroblast growth factor receptor 1	0.867
Ednra	endothelin receptor type A	0.859
Foxc2	forkhead box C2	0.856
Prrx1	paired related homeobox 1	0.829
Tgfbr1	transforming growth factor, beta receptor I	0.823	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.797
Chrd	chordin	0.747
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.743
Hand2	heart and neural crest derivatives expressed transcript 2	0.710
Bmp7	bone morphogenetic protein 7	0.710
Zeb1	zinc finger E-box binding homeobox 1	0.686
Tbx1	T-box 1	0.683
Smo	smoothened homolog (Drosophila)	0.654
Vegfa	vascular endothelial growth factor A	0.653
Pten	phosphatase and tensin homolog	0.632
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.605
Smad3	MAD homolog 3 (Drosophila)	0.590
Jag1	jagged 1	0.580
Nos3	nitric oxide synthase 3, endothelial cell	0.569
Pitx2	paired-like homeodomain transcription factor 2	0.460
Fgf10	fibroblast growth factor 10	0.456
Rxra	retinoid X receptor alpha	0.443
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.432
Rarb	retinoic acid receptor, beta	0.421
Fgfr3	fibroblast growth factor receptor 3	0.394	Mouse
Gli2	GLI-Kruppel family member GLI2	0.391
Tcfap2a	transcription factor AP-2, alpha	0.386
Msx1	homeobox, msh-like 1	0.384
Pax2	paired box gene 2	0.375
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.343
Dlx5	distal-less homeobox 5	0.338
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.327
Prrx2	paired related homeobox 2	0.313
Pbx1	pre B-cell leukemia transcription factor 1	0.291
Ece1	endothelin converting enzyme 1	0.278
Hoxa1	homeobox A1	0.274
Eng	endoglin	0.254
Egfr	epidermal growth factor receptor	0.250
Rara	retinoic acid receptor, alpha	0.250
Esr1	estrogen receptor 1 (alpha)	0.235
Efnb2	ephrin B2	0.231
Vangl2	vang-like 2 (van gogh, Drosophila)	0.227
Smad4	MAD homolog 4 (Drosophila)	0.225
Hoxa3	homeobox A3	0.201
Ptch1	patched homolog 1	0.185
Esr2	estrogen receptor 2 (beta)	0.179
Foxg1	forkhead box G1	0.177
Gsc	goosecoid homeobox	0.176
Otx2	orthodenticle homolog 2 (Drosophila)	0.154
Hand1	heart and neural crest derivatives expressed transcript 1	0.148
Tbx3	T-box 3	0.147
Bmp5	bone morphogenetic protein 5	0.145
Tgfbr3	transforming growth factor, beta receptor III	0.141
Pgr	progesterone receptor	0.136
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.135
Meox2	mesenchyme homeobox 2	0.126
Bmp2	bone morphogenetic protein 2	0.119
Pax8	paired box gene 8	0.114
Nog	noggin	0.112
Ar	androgen receptor	0.111
Msx2	homeobox, msh-like 2	0.109
Pax6	paired box gene 6	0.106
Nf1	neurofibromatosis 1	0.103
Npr3	natriuretic peptide receptor 3	0.102
Runx2	runt related transcription factor 2	0.101
Wnt3a	wingless-related MMTV integration site 3A	0.097
Wnt7a	wingless-related MMTV integration site 7A	0.088
Lmx1b	LIM homeobox transcription factor 1 beta	0.082
Adam17	a disintegrin and metallopeptidase domain 17	0.073
Fzd1	frizzled homolog 1 (Drosophila)	0.073
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.068
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.067
Gpc3	glypican 3	0.067
Nodal	nodal	0.061
Sox2	SRY-box containing gene 2	0.061
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.060
Mesp1	mesoderm posterior 1	0.059
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.059
Lrp6	low density lipoprotein receptor-related protein 6	0.058
Fbn1	fibrillin 1	0.056
Trp53	transformation related protein 53	0.055
Isl1	ISL1 transcription factor, LIM/homeodomain	0.054
Gja1	gap junction protein, alpha 1	0.054
Fgf9	fibroblast growth factor 9	0.053
Nkx2-1	NK2 homeobox 1	0.053
Gdnf	glial cell line derived neurotrophic factor	0.052
Twist2	twist homolog 2 (Drosophila)	0.052
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.052
Kl	klotho	0.052
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.051
Tcf21	transcription factor 21	0.051
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.049
Lhx1	LIM homeobox protein 1	0.048
Hmx1	H6 homeobox 1	0.048
Gbx2	gastrulation brain homeobox 2	0.047
Foxf1a	forkhead box F1a	0.047
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.045
Foxf2	forkhead box F2	0.045	Mouse
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.044
Kif3a	kinesin family member 3A	0.043
Hoxa13	homeobox A13	0.043
Itga8	integrin alpha 8	0.043
Hoxd13	homeobox D13	0.043
Tbx15	T-box 15	0.042
Foxa2	forkhead box A2	0.042
Mgat3	mannoside acetylglucosaminyltransferase 3	0.041
Hoxa2	homeobox A2	0.040
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.039
Fgfrl1	fibroblast growth factor receptor-like 1	0.039
Fshr	follicle stimulating hormone receptor	0.036
Ptgs2	prostaglandin-endoperoxide synthase 2	0.036
Braf	Braf transforming gene	0.035
Acvrl1	activin A receptor, type II-like 1	0.035	Mouse
Gata6	GATA binding protein 6	0.035
Shc1	src homology 2 domain-containing transforming protein C1	0.033
Wnt4	wingless-related MMTV integration site 4	0.033
Grb10	growth factor receptor bound protein 10	0.032
Wwc2	WW, C2 and coiled-coil domain containing 2	0.032
Inha	inhibin alpha	0.032
Chd7	chromodomain helicase DNA binding protein 7	0.031
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.030
Kiss1	KiSS-1 metastasis-suppressor	0.030
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.030
Ext1	exostoses (multiple) 1	0.030
Col13a1	collagen, type XIII, alpha 1	0.029
Psen1	presenilin 1	0.029
Wls	wntless homolog (Drosophila)	0.029
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.028
Trp63	transformation related protein 63	0.028
Ret	ret proto-oncogene	0.027
Alx4	aristaless-like homeobox 4	0.027
Smad6	MAD homolog 6 (Drosophila)	0.027
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.027
Cdh5	cadherin 5	0.026
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.026	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.025
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.025
Kiss1r	KISS1 receptor	0.025
Sox11	SRY-box containing gene 11	0.025
Fgf18	fibroblast growth factor 18	0.024
Lep	leptin	0.024
Il6st	interleukin 6 signal transducer	0.024
Itgav	integrin alpha V	0.024
Hoxa5	homeobox A5	0.024
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.024
Jag2	jagged 2	0.023
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.023
Clic3	chloride intracellular channel 3	0.023
Foxe3	forkhead box E3	0.023
Idua	iduronidase, alpha-L-	0.023
Pcdh12	protocadherin 12	0.023
Ntf3	neurotrophin 3	0.023
Dlx6	distal-less homeobox 6	0.023
Bdnf	brain derived neurotrophic factor	0.022
Col12a1	collagen, type XII, alpha 1	0.022
Wnt11	wingless-related MMTV integration site 11	0.021
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.021
Bmper	BMP-binding endothelial regulator	0.021
Smad2	MAD homolog 2 (Drosophila)	0.020
Angpt1	angiopoietin 1	0.020
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.020
Gata4	GATA binding protein 4	0.020
Inhbb	inhibin beta-B	0.019
Hoxa11	homeobox A11	0.019
Lox	lysyl oxidase	0.019
Ptk7	PTK7 protein tyrosine kinase 7	0.019
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.018
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.018
Smad5	MAD homolog 5 (Drosophila)	0.018
Vcl	vinculin	0.017
Adam10	a disintegrin and metallopeptidase domain 10	0.017
Bmi1	Bmi1 polycomb ring finger oncogene	0.017
Rem1	rad and gem related GTP binding protein 1	0.017
Itga3	integrin alpha 3	0.017
Hoxd11	homeobox D11	0.017
Rdh10	retinol dehydrogenase 10 (all-trans)	0.017
Kcnk3	potassium channel, subfamily K, member 3	0.017
Thrb	thyroid hormone receptor beta	0.017
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.016
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.016
Ids	iduronate 2-sulfatase	0.016
Csf1	colony stimulating factor 1 (macrophage)	0.016
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.016
Cnn1	calponin 1	0.016
Lepr	leptin receptor	0.016
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.016
Gli1	GLI-Kruppel family member GLI1	0.016
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.016
Ager	advanced glycosylation end product-specific receptor	0.016
Tbx2	T-box 2	0.015
Gdf11	growth differentiation factor 11	0.015
Srcin1	SRC kinase signaling inhibitor 1	0.015
Ghr	growth hormone receptor	0.015
Oprd1	opioid receptor, delta 1	0.015
Wnt5a	wingless-related MMTV integration site 5A	0.015
Xiap	X-linked inhibitor of apoptosis	0.015
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.015
Sftpb	surfactant associated protein B	0.015
Rb1	retinoblastoma 1	0.015
Col4a3	collagen, type IV, alpha 3	0.015
Podxl	podocalyxin-like	0.015
Otx1	orthodenticle homolog 1 (Drosophila)	0.014
Cpd	carboxypeptidase D	0.014
Pitx1	paired-like homeodomain transcription factor 1	0.014
Hif1a	hypoxia inducible factor 1, alpha subunit	0.014
Tgfa	transforming growth factor alpha	0.014
Snai1	snail homolog 1 (Drosophila)	0.014
Yap1	yes-associated protein 1	0.014
Ddr2	discoidin domain receptor family, member 2	0.014
Irs2	insulin receptor substrate 2	0.014
Bdkrb2	bradykinin receptor, beta 2	0.013
Btbd3	BTB (POZ) domain containing 3	0.013
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.013
Col2a1	collagen, type II, alpha 1	0.013
Gata3	GATA binding protein 3	0.013
Fzd4	frizzled homolog 4 (Drosophila)	0.013
Prkg1	protein kinase, cGMP-dependent, type I	0.013
Bcl2	B-cell leukemia/lymphoma 2	0.013
Plxna1	plexin A1	0.013
Hipk3	homeodomain interacting protein kinase 3	0.013
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.013
Atf2	activating transcription factor 2	0.013
Wnt6	wingless-related MMTV integration site 6	0.013
Pou4f3	POU domain, class 4, transcription factor 3	0.013
Dlg1	discs, large homolog 1 (Drosophila)	0.013
Gpr182	G protein-coupled receptor 182	0.013
Krt19	keratin 19	0.013
Hoxb3	homeobox B3	0.013
Prlr	prolactin receptor	0.012
Eda	ectodysplasin-A	0.012
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.012
Hoxa7	homeobox A7	0.012
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.012
Hamp	hepcidin antimicrobial peptide	0.012
Hmx2	H6 homeobox 2	0.012
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.012
Cdk14	cyclin-dependent kinase 14	0.012
Hoxa10	homeobox A10	0.012
Smad7	MAD homolog 7 (Drosophila)	0.012
Fst	follistatin	0.012
Shc3	src homology 2 domain-containing transforming protein C3	0.012
Dmrt1	doublesex and mab-3 related transcription factor 1	0.012
Mkl2	MKL/myocardin-like 2	0.012
Kit	kit oncogene	0.011
Pkd1	polycystic kidney disease 1 homolog	0.011
Akt3	thymoma viral proto-oncogene 3	0.011
Mme	membrane metallo endopeptidase	0.011
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.011
Aff2	AF4/FMR2 family, member 2	0.011
Dll1	delta-like 1 (Drosophila)	0.011
Ptprg	protein tyrosine phosphatase, receptor type, G	0.011
Stat3	signal transducer and activator of transcription 3	0.011
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.011
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.011
Npr2	natriuretic peptide receptor 2	0.011
Emp2	epithelial membrane protein 2	0.011
Wnt9b	wingless-type MMTV integration site 9B	0.011
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.011
Epha1	Eph receptor A1	0.011
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.011
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Syt7	synaptotagmin VII	0.011
Grem1	gremlin 1	0.011
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.011
Acan	aggrecan	0.010
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.010
Myoz3	myozenin 3	0.010
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.010
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.010
Ptrf	polymerase I and transcript release factor	0.010
Barx2	BarH-like homeobox 2	0.010
Il10ra	interleukin 10 receptor, alpha	0.010
Lmx1a	LIM homeobox transcription factor 1 alpha	0.010
Emx2	empty spiracles homolog 2 (Drosophila)	0.010