IMP

Process View

Mus musculus

4 genes annotated in mouse

wnt signaling pathway involved in somitogenesis

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "wnt signaling pathway involved in somitogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "wnt signaling pathway involved in somitogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Vangl2	vang-like 2 (van gogh, Drosophila)	0.999
Shh	sonic hedgehog	0.997
Bmp4	bone morphogenetic protein 4	0.996
Gsk3b	glycogen synthase kinase 3 beta	0.995
Lrp6	low density lipoprotein receptor-related protein 6	0.994
Fgfr1	fibroblast growth factor receptor 1	0.994
Sfrp1	secreted frizzled-related protein 1	0.979
Sfrp2	secreted frizzled-related protein 2	0.975
Smo	smoothened homolog (Drosophila)	0.940
Gli2	GLI-Kruppel family member GLI2	0.925
Gas1	growth arrest specific 1	0.917
Foxc1	forkhead box C1	0.904
Tbx3	T-box 3	0.895
Wnt5a	wingless-related MMTV integration site 5A	0.863
Pitx2	paired-like homeodomain transcription factor 2	0.845
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.833
Smad6	MAD homolog 6 (Drosophila)	0.832
Pbx1	pre B-cell leukemia transcription factor 1	0.821
Apc	adenomatosis polyposis coli	0.796
Otx2	orthodenticle homolog 2 (Drosophila)	0.781
Foxc2	forkhead box C2	0.772
Sox11	SRY-box containing gene 11	0.768
Msx1	homeobox, msh-like 1	0.762
Psen1	presenilin 1	0.715
Gpc3	glypican 3	0.694
Prrx1	paired related homeobox 1	0.670
Fgfr3	fibroblast growth factor receptor 3	0.568
Ptk7	PTK7 protein tyrosine kinase 7	0.562
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.561
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.540
Meox2	mesenchyme homeobox 2	0.535
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.502
Axin1	axin 1	0.486	Zebrafish
Bmp7	bone morphogenetic protein 7	0.484
Pkd1	polycystic kidney disease 1 homolog	0.477
Wnt3a	wingless-related MMTV integration site 3A	0.466
T	brachyury	0.458
Pax3	paired box gene 3	0.452
Tcfap2a	transcription factor AP-2, alpha	0.409
Lrp5	low density lipoprotein receptor-related protein 5	0.403	Mouse
Msx2	homeobox, msh-like 2	0.403
Tgfb2	transforming growth factor, beta 2	0.395
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.361
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.347
Sox2	SRY-box containing gene 2	0.336
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.312
Prrx2	paired related homeobox 2	0.303
Twist2	twist homolog 2 (Drosophila)	0.297
Zeb1	zinc finger E-box binding homeobox 1	0.297
Ptch1	patched homolog 1	0.297
Smad7	MAD homolog 7 (Drosophila)	0.285
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.284
Smad3	MAD homolog 3 (Drosophila)	0.267
Rarg	retinoic acid receptor, gamma	0.257
Fzd2	frizzled homolog 2 (Drosophila)	0.223
Apoe	apolipoprotein E	0.215
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.211
Pax2	paired box gene 2	0.209
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.205
Jag1	jagged 1	0.205
Rnf111	ring finger 111	0.202
Hes1	hairy and enhancer of split 1 (Drosophila)	0.194
En1	engrailed 1	0.192
Fgf8	fibroblast growth factor 8	0.187
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.184
Hoxa1	homeobox A1	0.173
Egfr	epidermal growth factor receptor	0.172
Hoxa2	homeobox A2	0.167
Lef1	lymphoid enhancer binding factor 1	0.163
Crtc3	CREB regulated transcription coactivator 3	0.159
Fzd1	frizzled homolog 1 (Drosophila)	0.157
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.155
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.142
Apaf1	apoptotic peptidase activating factor 1	0.142
Lrp4	low density lipoprotein receptor-related protein 4	0.137	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	0.136
Efnb1	ephrin B1	0.133
Eya1	eyes absent 1 homolog (Drosophila)	0.130
Dab2	disabled homolog 2 (Drosophila)	0.125
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.123
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.119
Capn6	calpain 6	0.113
Cachd1	cache domain containing 1	0.106
Npc1	Niemann Pick type C1	0.099
Efnb2	ephrin B2	0.098
Trp63	transformation related protein 63	0.095
Runx2	runt related transcription factor 2	0.095
Lrp2	low density lipoprotein receptor-related protein 2	0.093	Mouse
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.093
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.092
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.092
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.089
Hoxc8	homeobox C8	0.085
Tbx1	T-box 1	0.084
Nynrin	NYN domain and retroviral integrase containing	0.084
Tbx2	T-box 2	0.083
Efs	embryonal Fyn-associated substrate	0.082
Meis2	Meis homeobox 2	0.082
Efna4	ephrin A4	0.080
Notch3	Notch gene homolog 3 (Drosophila)	0.080
Col1a1	collagen, type I, alpha 1	0.079
Twist1	twist homolog 1 (Drosophila)	0.077
Foxa2	forkhead box A2	0.077
Hoxa5	homeobox A5	0.077
Npr3	natriuretic peptide receptor 3	0.076
Bmp1	bone morphogenetic protein 1	0.075
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.074
Foxg1	forkhead box G1	0.073
Rarb	retinoic acid receptor, beta	0.072
Zfp503	zinc finger protein 503	0.071
Mks1	Meckel syndrome, type 1	0.069
Agtr2	angiotensin II receptor, type 2	0.064
Umod	uromodulin	0.062
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.061
Hoxb6	homeobox B6	0.060
Htt	huntingtin	0.059
Tead2	TEA domain family member 2	0.057
Bmp5	bone morphogenetic protein 5	0.057
Notch2	Notch gene homolog 2 (Drosophila)	0.056
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.056
Sertad2	SERTA domain containing 2	0.055
Gbx2	gastrulation brain homeobox 2	0.055
Bnc1	basonuclin 1	0.053
Zfp185	zinc finger protein 185	0.053
Nodal	nodal	0.051
Pax6	paired box gene 6	0.051
Hoxd11	homeobox D11	0.050
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.050
Dlx5	distal-less homeobox 5	0.050
Dll1	delta-like 1 (Drosophila)	0.049
Fzd8	frizzled homolog 8 (Drosophila)	0.049
Tbx15	T-box 15	0.049
Nog	noggin	0.048
Itga3	integrin alpha 3	0.047
Wls	wntless homolog (Drosophila)	0.046
Sox9	SRY-box containing gene 9	0.046
Ddr2	discoidin domain receptor family, member 2	0.045
Chd7	chromodomain helicase DNA binding protein 7	0.045
Zfhx3	zinc finger homeobox 3	0.045
Plin1	perilipin 1	0.045
Otx1	orthodenticle homolog 1 (Drosophila)	0.044
App	amyloid beta (A4) precursor protein	0.044
Tcf21	transcription factor 21	0.044
Bcl2	B-cell leukemia/lymphoma 2	0.044
Notch1	Notch gene homolog 1 (Drosophila)	0.042
Tcfap2c	transcription factor AP-2, gamma	0.041
Hoxa10	homeobox A10	0.041
Col11a1	collagen, type XI, alpha 1	0.040
Igfbp4	insulin-like growth factor binding protein 4	0.040
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.040
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.040
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.039
Adam17	a disintegrin and metallopeptidase domain 17	0.039
Pten	phosphatase and tensin homolog	0.038
Zic3	zinc finger protein of the cerebellum 3	0.037
Fgf9	fibroblast growth factor 9	0.037
Hoxc4	homeobox C4	0.037
Fbln1	fibulin 1	0.037
Emx2	empty spiracles homolog 2 (Drosophila)	0.036
Fzd7	frizzled homolog 7 (Drosophila)	0.036
Lpar3	lysophosphatidic acid receptor 3	0.036
Pofut1	protein O-fucosyltransferase 1	0.036
Esr1	estrogen receptor 1 (alpha)	0.035
Hoxd4	homeobox D4	0.034
Col2a1	collagen, type II, alpha 1	0.034
Rara	retinoic acid receptor, alpha	0.034
Igf1r	insulin-like growth factor I receptor	0.034
Sox4	SRY-box containing gene 4	0.033
Hoxd13	homeobox D13	0.032
Hoxd8	homeobox D8	0.032
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.031
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.031
Zfhx4	zinc finger homeodomain 4	0.030
Hoxd9	homeobox D9	0.030
Pax8	paired box gene 8	0.030
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.030
Nfib	nuclear factor I/B	0.029
Efna2	ephrin A2	0.029
Hoxc6	homeobox C6	0.029
Bmper	BMP-binding endothelial regulator	0.029
Gli1	GLI-Kruppel family member GLI1	0.028
Cldn8	claudin 8	0.028
Irx3	Iroquois related homeobox 3 (Drosophila)	0.028
Ptprf	protein tyrosine phosphatase, receptor type, F	0.028
Lama5	laminin, alpha 5	0.028
Hoxa9	homeobox A9	0.027
Peg3	paternally expressed 3	0.027
Kif3a	kinesin family member 3A	0.027
Fgf10	fibroblast growth factor 10	0.026
Pthlh	parathyroid hormone-like peptide	0.026
Plagl1	pleiomorphic adenoma gene-like 1	0.026
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.026
Hoxa11	homeobox A11	0.026
Rhod	ras homolog gene family, member D	0.025
Cldn6	claudin 6	0.025
Crebbp	CREB binding protein	0.025
Yap1	yes-associated protein 1	0.025
Wnt1	wingless-related MMTV integration site 1	0.024
Bmp2	bone morphogenetic protein 2	0.024
Pkdcc	protein kinase domain containing, cytoplasmic	0.024
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.024
Rdh10	retinol dehydrogenase 10 (all-trans)	0.023
Numb	numb gene homolog (Drosophila)	0.023
Hoxb3	homeobox B3	0.023
Fjx1	four jointed box 1 (Drosophila)	0.023
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.022
Mrc2	mannose receptor, C type 2	0.022
Ephb3	Eph receptor B3	0.022
Axin2	axin2	0.022
Sox13	SRY-box containing gene 13	0.022
Dlk1	delta-like 1 homolog (Drosophila)	0.022
Ephb4	Eph receptor B4	0.022
Hoxb2	homeobox B2	0.022
Nos3	nitric oxide synthase 3, endothelial cell	0.022
Pparg	peroxisome proliferator activated receptor gamma	0.022
Hoxd10	homeobox D10	0.021
Gata3	GATA binding protein 3	0.021
Nfia	nuclear factor I/A	0.021
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.021
Sall4	sal-like 4 (Drosophila)	0.021
Gata6	GATA binding protein 6	0.021
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.021
Wnt5b	wingless-related MMTV integration site 5B	0.021
Srpx	sushi-repeat-containing protein	0.020
Wt1	Wilms tumor 1 homolog	0.020
Alx1	ALX homeobox 1	0.020
Ctf1	cardiotrophin 1	0.020
Acvr1	activin A receptor, type 1	0.020
Lama1	laminin, alpha 1	0.020
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.020
Folr1	folate receptor 1 (adult)	0.020
Lrrk2	leucine-rich repeat kinase 2	0.020
Hoxb5	homeobox B5	0.019
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.019
Itga8	integrin alpha 8	0.019
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.019	Mouse
Aebp1	AE binding protein 1	0.019
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.019
Cav1	caveolin 1, caveolae protein	0.018
Irf6	interferon regulatory factor 6	0.018
Neo1	neogenin	0.018
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.018
Cdh1	cadherin 1	0.018
Col12a1	collagen, type XII, alpha 1	0.018
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.018
Amotl2	angiomotin-like 2	0.017
Mmp11	matrix metallopeptidase 11	0.017
Cxadr	coxsackie virus and adenovirus receptor	0.017
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.017
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.017
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.017
Smad2	MAD homolog 2 (Drosophila)	0.017
Mecom	MDS1 and EVI1 complex locus	0.017
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.017
Fn1	fibronectin 1	0.017
Ext1	exostoses (multiple) 1	0.017
Foxa1	forkhead box A1	0.017
Tll1	tolloid-like	0.017
Vnn1	vanin 1	0.016
Gja3	gap junction protein, alpha 3	0.016
Ihh	Indian hedgehog	0.016
Ltbr	lymphotoxin B receptor	0.016
Irs1	insulin receptor substrate 1	0.016
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.016
Hhat	hedgehog acyltransferase	0.016
Col4a3	collagen, type IV, alpha 3	0.016
She	src homology 2 domain-containing transforming protein E	0.016
Plekha7	pleckstrin homology domain containing, family A member 7	0.016
Ptms	parathymosin	0.016
Frem1	Fras1 related extracellular matrix protein 1	0.016
Cdh11	cadherin 11	0.016
Lmx1a	LIM homeobox transcription factor 1 alpha	0.016
Col4a4	collagen, type IV, alpha 4	0.015
Trp53	transformation related protein 53	0.015
Pick1	protein interacting with C kinase 1	0.015
Sox7	SRY-box containing gene 7	0.015
Anpep	alanyl (membrane) aminopeptidase	0.015
Ptn	pleiotrophin	0.015
Tpbg	trophoblast glycoprotein	0.015
Lhx1	LIM homeobox protein 1	0.015
Grb10	growth factor receptor bound protein 10	0.015
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.015
Col8a1	collagen, type VIII, alpha 1	0.015
Pitx1	paired-like homeodomain transcription factor 1	0.015
Nrk	Nik related kinase	0.015
Heph	hephaestin	0.015
Unc5c	unc-5 homolog C (C. elegans)	0.015
Irx5	Iroquois related homeobox 5 (Drosophila)	0.014
Fst	follistatin	0.014
Dmrt2	doublesex and mab-3 related transcription factor 2	0.014
Hoxb8	homeobox B8	0.014
Cic	capicua homolog (Drosophila)	0.014
Rxra	retinoid X receptor alpha	0.014
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.014
Shox2	short stature homeobox 2	0.014
Mertk	c-mer proto-oncogene tyrosine kinase	0.014
Klf15	Kruppel-like factor 15	0.014
Ldlr	low density lipoprotein receptor	0.014
Lpar1	lysophosphatidic acid receptor 1	0.014
Hoxb4	homeobox B4	0.014
Hoxc5	homeobox C5	0.014
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.013
Tnks1bp1	tankyrase 1 binding protein 1	0.013
Wwc2	WW, C2 and coiled-coil domain containing 2	0.013
Hmga2	high mobility group AT-hook 2	0.013
Alx3	aristaless-like homeobox 3	0.013
Gsc	goosecoid homeobox	0.013
Isl1	ISL1 transcription factor, LIM/homeodomain	0.013
Snai1	snail homolog 1 (Drosophila)	0.013
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.013
Thbs1	thrombospondin 1	0.013
Ano1	anoctamin 1, calcium activated chloride channel	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Kl	klotho	0.013
Tmprss2	transmembrane protease, serine 2	0.013
Aif1l	allograft inflammatory factor 1-like	0.012
Col4a5	collagen, type IV, alpha 5	0.012
Smad4	MAD homolog 4 (Drosophila)	0.012
Gpc6	glypican 6	0.012
Barx1	BarH-like homeobox 1	0.012
Grik1	glutamate receptor, ionotropic, kainate 1	0.012
Igfbp5	insulin-like growth factor binding protein 5	0.012
Id4	inhibitor of DNA binding 4	0.012
Emx1	empty spiracles homolog 1 (Drosophila)	0.012
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.012
Vangl1	vang-like 1 (van gogh, Drosophila)	0.012
Gdf5	growth differentiation factor 5	0.012
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.012
Mmp2	matrix metallopeptidase 2	0.012
Glg1	golgi apparatus protein 1	0.012
Fzd6	frizzled homolog 6 (Drosophila)	0.011
Pax9	paired box gene 9	0.011
Upk3b	uroplakin 3B	0.011
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.011
Gm98	predicted gene 98	0.011
Cldn7	claudin 7	0.011
Vegfa	vascular endothelial growth factor A	0.011
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.011
Thbs3	thrombospondin 3	0.011
Sh3rf1	SH3 domain containing ring finger 1	0.011
Ncam1	neural cell adhesion molecule 1	0.011
Ski	ski sarcoma viral oncogene homolog (avian)	0.011
Ncoa3	nuclear receptor coactivator 3	0.011
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.011
Irx2	Iroquois related homeobox 2 (Drosophila)	0.011
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.011
Fzd3	frizzled homolog 3 (Drosophila)	0.011
Hoxd1	homeobox D1	0.011
Bcar1	breast cancer anti-estrogen resistance 1	0.011
Crh	corticotropin releasing hormone	0.011
Lpar4	lysophosphatidic acid receptor 4	0.011
Mkrn3	makorin, ring finger protein, 3	0.011
Gjb3	gap junction protein, beta 3	0.010
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.010
Cldn4	claudin 4	0.010
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.010
Gdf10	growth differentiation factor 10	0.010
Hoxd3	homeobox D3	0.010
Tcfap2b	transcription factor AP-2 beta	0.010
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.010
Psors1c2	psoriasis susceptibility 1 candidate 2 (human)	0.010
Edar	ectodysplasin-A receptor	0.010
Igfbp2	insulin-like growth factor binding protein 2	0.010
Cldn3	claudin 3	0.010
Ntf3	neurotrophin 3	0.010
Zcchc14	zinc finger, CCHC domain containing 14	0.010
Ptk2	PTK2 protein tyrosine kinase 2	0.010
Tead3	TEA domain family member 3	0.010
Krt7	keratin 7	0.010
Peg10	paternally expressed 10	0.010